Prevalence of Carotid Artery Stenosis in Southern China: A Retrospective, Cross-Sectional Study

ObjectiveSerum uric acid (SUA) has been associated with cardiovascular diseases, including atherosclerosis and carotid artery stenosis. However, data on the relationship between SUA level and proximal extracranial artery stenosis (PEAS) are limited. Therefore, this study investigates the association between SUA levels and the risk of PEAS in asymptomatic Chinese population.SettingThis community-based cross-sectional study was conducted in Jidong Community Hospital, Tangshan, Hebei, China between July 2013 and August 2014.ParticipantsThe study examined 3325 asymptomatic participants (40–60 years) to evaluate the risk of PEAS.ResultsFor the participants stratified into quartiles based on gender-specific SUA levels, the prevalence of PEAS increased from Q1 to Q4 from 12.3% to 29.8% in the vertebral artery (VA), and from 2.8% to 5.8% in the common carotid artery. The proportion of PEAS relative to the detected number of arterial stenosis was lower in Q1 than in Q2–Q4. The multivariable ORs and 95% CI of PEAS in the second through fourth compared with the lowest quartiles for arterial stenosis were 1.278 (0.980 to 1.665), 1.117 (0.851 to 1.468) and 1.375 (1.033 to 1.830) (ptrend=0.0399); and for VA stenosis, 1.285 (0.966 to 1.709), 1.085 (0.808 to 1.457) and 1.439 (1.061 to 1.952) (ptrend=0.0235).ConclusionElevated SUA concentration is significantly associated with PEAS in an asymptomatic middle-aged Chinese population, and vertebral arteries appeared to be the most vulnerable vessels.

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Carotid Artery Stenosis in Diabetic Patients Presenting With Acute Ischemic Stroke

Pakistan Journal of Medicine and Dentistry ◽

10.36283/pjmd9-1/010 ◽

2020 ◽

Author(s):

Ahsan Ashfaq

Keyword(s):

Ischemic Stroke ◽

Carotid Artery ◽

Acute Ischemic Stroke ◽

Carotid Artery Stenosis ◽

Cross Sectional Study ◽

Artery Stenosis ◽

P Value ◽

Diabetic Patients ◽

Chi Square ◽

Cross Sectional

Background: Stroke is the commonest life-threatening neurological disorder. The Abnormal narrowing or stenosis of the Carotid Artery is a major determinant of ischemic stroke in diabetic patients. The main objective of study was to estimate the frequency of carotid artery stenosis in diabetic patients presenting with acute ischemic stroke. Methods: This was a Cross-Sectional study conducted at Medicine wards Jinnah Post-Graduate Medical Centre, Karachi from 5th December 2014 to 5th June 2015. Total 101 patients were included. During the hospitalization, patients were subjected to carotid Doppler ultrasonography to assess carotid artery stenosis. Patients were provided routine medical care during the hospitalization. Data was analyzed using SPSS v23.0. Chi-Square was used to analyze the differences between the categories. The p-value of <0.05 was considered as significance. Results: Total 101 patients were included in the study. There were 71.8% males and 28.2% females. The mean age was 53.7±10.2 years. On analysis of risk factors, it was observed that 59% patients had hypertension, 34.2% patients were obese, 34.2% patients had dyslipidemia, 51.3% patients had history of smoking. On analysis of carotid artery stenosis among the diabetics, it was observed that 20.8% diabetics had carotid artery stenosis. Conclusion: Stenosis of Carotid artery was common in patients suffering from acute ischemic stroke and diabetes mellitus. Among modifiable risk factor in patients with stroke having carotid artery stenosis, Hypertension was most common whereas fasting blood sugar FBS level greater than 100 g/dl lead to increased chances of having carotid artery stenosis.

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The association between metabolic syndrome and asymptomatic carotid artery stenosis in menopausal women: a cross-sectional study in a Chinese population

Therapeutics and Clinical Risk Management ◽

10.2147/tcrm.s177265 ◽

2018 ◽

Vol Volume 14 ◽

pp. 2183-2188 ◽

Cited By ~ 3

Author(s):

Bin Zhu ◽

Lei Zhang ◽

Xiao Ping Cheng ◽

Lei Wang ◽

Yue Tian ◽

...

Keyword(s):

Metabolic Syndrome ◽

Carotid Artery ◽

Carotid Artery Stenosis ◽

Chinese Population ◽

Cross Sectional Study ◽

Sectional Study ◽

Asymptomatic Carotid ◽

Cross Sectional ◽

Menopausal Women ◽

Asymptomatic Carotid Artery Stenosis

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Plaque Length Predicts the Incidence of Microembolic Signals in Acute Anterior Circulation Stroke

Disease Markers ◽

10.1155/2021/2005369 ◽

2021 ◽

Vol 2021 ◽

pp. 1-7

Author(s):

Liming Zhao ◽

Hongqin Zhao ◽

Yicheng Xu ◽

Aijuan Zhang ◽

Jiatang Zhang ◽

...

Keyword(s):

Carotid Artery ◽

Carotid Artery Stenosis ◽

Carotid Plaque ◽

Intima Media Thickness ◽

Roc Curves ◽

Cross Sectional Study ◽

Artery Stenosis ◽

Anterior Circulation ◽

Cross Sectional ◽

The Relationship

Microembolic signals (MES) of the carotid artery are associated with plaque destabilization and reoccurrence of stroke. Previous studies have focused primarily on the degree of carotid artery stenosis and plaque components, and the relationship between plaque length and microembolic sign has received little attention. We aimed to find the association between carotid plaque length (CPL) and the presence of MES. We conducted a retrospective observational cross-sectional study. A total of 84 acute anterior-circulation ischemic stroke/transient ischemic attack (TIA) patients with carotid artery atherosclerosis were classified into an MES-positive (MES+) group and MES-negative (MES−) group. We measured multiple parameters of carotid plaque size (length, thickness) in each patient and evaluated the relationship between different plaque parameters and occurrence of MES. We found that male, carotid artery stenosis (CAS), CPL, carotid plaque thickness (CPT), and intima-media thickness (IMT) of the carotid artery were each significantly different between two groups (all P < 0.05 ). The multivariate analysis showed CPL (odds ratio (OR), 1.109; 95% CI, 1.044–1.177; P = 0.001 ) to be independently associated with the presence of MES. The areas under the ROC curves (AUCs) for CPL for predicting MES were 0.777 (95% CI, 0.640–0.914; P < 0.001 ). The cutoff value of CPL for predicting MES was 16.7 mm, with a sensitivity of 88.2% and a specificity of 77.6%. We found that CPL was a meaningful independent predictor of MES. Therefore, CPL may be useful for risk stratification of long and nonstenotic plaques in anterior circulation stroke.

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