scholarly journals Brucellosis in Camels and Humans: Seroprevalence and Associated Risk Factors in Amibara District of Afar Region, Ethiopia

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Fekadu Gutema Wegi ◽  
Kebede Amenu ◽  
Adugna Chalchisa ◽  
Gezahegne Mamo
Keyword(s):  
Risk Factors ◽  
Close Contact ◽  
Mammalian Species ◽  
Raw Milk ◽  
Cross Sectional Study ◽  
Public Health Importance ◽  
Cross Sectional ◽  
Afar Region ◽  
Human Sera ◽  
Associated Risk Factors

Brucellosis is an important neglected zoonotic disease caused by infection with bacteria of the genus Brucella affecting different mammalian species including humans. A cross-sectional study was conducted to estimate the seroprevalence of brucellosis in camels and humans and its associated risk factors in Amibara District of Afar Region in Northeast Ethiopia, from October 2019 to May 2020. A total of 250 camel and 120 human sera were serially tested using the Rose Bengal plate test (RBPT) and complement fixation test (CFT). The overall seroprevalence of camel brucellosis in this study was 7.6% (95% CI: 4.9–11.56) by RBPT and 3.2% (95% CI: 1.63–6.2) by combined RBPT and CFT. In humans, twelve (10%) of the collected sera were positive by RBPT among which only four of them (3.33%) were positive by CFT. The risk factor analysis indicated that age, body condition, number of parity, and abortion history were significantly associated with Brucella seropositivity in camel ( P  ≤ 0.05). In humans, occupation and nonprotective handling of dystocia cases showed an apparent association with Brucella seropositivity. The results of this study indicated that brucellosis is a common health problem in camels and humans in Amibara District of Afar Region. The public health importance of this disease is associated with raw milk consumption and close contact with the animals having history of recent abortion. Therefore, controlling the risk factors, establishing Brucella diagnostic service in human clinics and hospitals, continuous social training with feedback assessments, and overall implementing of One Health approach framework to attain optimal health for people and domestic animals in area are recommended to safeguard the health of society.

scholarly journals Brucellosis in camel and human: Seroprevalence and associated risk factors in Amibara district of Afar region, Ethiopia

2021 ◽  
Author(s):  
Fekadu Gutema ◽  
Prof Kebede Amenu ◽  
Adugna Chalchisa ◽  
Prof Gezahegn Mamo
Keyword(s):  
Risk Factors ◽  
Close Contact ◽  
Mammalian Species ◽  
Raw Milk ◽  
Cross Sectional Study ◽  
Public Health Importance ◽  
Cross Sectional ◽  
North East ◽  
Afar Region ◽  
Associated Risk Factors

Abstract Background: Brucellosis is an important neglected zoonotic disease caused by infection with bacteria of the genus Brucella affecting different mammalian species including man. A cross-sectional study was conducted to estimate the seroprevalence of brucellosis in camels and human and its associated risk factors in Amibara district of Afar region, North east Ethiopia from October 2019 to May 2020Result: A total of 250 camel and 120 human sera were serially tested using the Rose Bengal Plate Test (RBPT), and Complement Fixation Test (CFT). The overall seroprevalence of camel brucellosis in the current study was 7.6% (95% CI: 4.9-11.56) using RBPT and 3.2% (95% CI: 1.63-6.2) by combined RBPT and CFT. In Human twelve (10%) of the collected sera were positive by RBPT among which only four of them (3.33%) were positive by CFT. The risk factors analysis indicated that, age, body condition, number of parity and abortion history were significantly associated with brucella seropositivity in camel(P≤0.05). In human, occupation and non-protective handling of dystocia cases showed apparent association with brucella seropositivity.Conclusion: The results of the present study indicated that, brucellosis is a common health problem in camel and human in Amibara district of Afar region. The public health importance of this disease is associated with raw milk consumption and close contact with the animals having history of recent abortion. Therefore, controlling the risk factors, establishing brucella diagnostic service in human clinics and hospitals, continuous social training with feedback assessments and overall implementing of One Health approach framework to attain optimal health for people and domestic animals in area are recommended to safeguard the health of society.

scholarly journals Seroprevalence and Associated Risk Factors of Brucellosis in Livestock and Residents of New Valley Governorate, Egypt

2020 ◽  
pp. 531-539
Author(s):  
Mohamed Said Diab ◽  
Sherif Abd Allah Zidan ◽  
Nermin Abdalla A. Hassan ◽  
Haitham Elaadli ◽  
Ahmed Mohamed Bayoumi
Keyword(s):  
Risk Factors ◽  
Raw Milk ◽  
Cross Sectional Study ◽  
Enzyme Linked Immunosorbent Assay ◽  
Human Brucellosis ◽  
Human Occupation ◽  
Serum Samples ◽  
Cross Sectional ◽  
Significant Difference ◽  
Associated Risk Factors

Brucellosis is a worldwide zoonotic disease which is now considered endemic in most parts of Egypt. A cross-sectional study was carried out from December 2018 to February 2020 to investigate the seroprevalence of brucellosis in humans and livestock residing in two regions located in New Valley Governorate, Egypt. A total of 1254 animals (673 cattle, 348 sheep, and 233 goats) and 523 human serum samples were examined for brucellosis using Rose Bengal test (RBT) and then randomly selected sera (15 from cattle, 7 from sheep, 3 from goats, and 45 from humans) were further analyzed by complement fixation test, enzyme-linked immunosorbent assay to compare and detect the sensitivity and specificity of RBT. The prevalence of brucellosis was 0% in cattle, sheep, and goats while it was 23.9% in humans using RBT. Concerning humans, there was a higher percentage of infection in EL Kharga (33.6%). The prevalence of this infection was also at a higher level among individuals aged above 40 years (28.57%). Furthermore, men (26.11%) were more inclined to be inflicted, compared to women (22.5%) with no significant difference. Considering the human occupation, abattoir workers were the most predominant group of people at risk (33.3%), followed by farmers (31.25%) and animal keepers (20.6%) while the lowest prevalence was demonstrated in the housewives where the prevalence was 18.8 %. As a result, risk factors of the age range, locality, time of infection, contact with animals, and occupational groups could significantly affect the prevalence of human brucellosis in the New Valley Governorate. In conclusion, brucellosis is an alarming problem among residents of the New Valley Governorate. Thus, reducing the prevalence in humans and animals in the region of study may include restriction of the marketing the raw milk and enhancing public health awareness.

scholarly journals Prevalence and risk factors of human brucellosis and malaria among patients with fever in malaria-endemic areas, attending health institutes in Awra and Gulina district, Afar Region, Ethiopia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sintayehu Mehari ◽  
Biruk Zerfu ◽  
Kassu Desta
Keyword(s):  
Risk Factors ◽  
Significant Risk ◽  
Raw Milk ◽  
Cross Sectional Study ◽  
Elisa Test ◽  
Human Brucellosis ◽  
Cross Sectional ◽  
Afar Region ◽  
Tropical Areas ◽  
Endemic Areas

Abstract Background Brucellosis is an important neglected bacterial zoonotic disease that has been affecting animals and humans for decades. Malaria has been considered major cause of illness in tropical areas, including Ethiopia. This study aimed to identify prevalence and risk factors of human brucellosis and malaria among patients with fever in malaria-endemic areas attending health institutes in Awra and Gulina district, Afar Region, Ethiopia. Methods A purposive cross-sectional study was conducted among febrile patients who attended health institutes in Awra and Gulina district of Afar region from February to May 2019. 3–5 ml blood samples were collected, thick and thin blood films were prepared and examined for malaria; serum was separated and tested for anti-Brucella using Rose Bengal Plate Test, and the seropositives were subjected to ELISA. Data were entered using EpiData3.1 and analyses were performed using Stata SE 14. Results A total of 444 febrile individuals (59.5% female) of age ranging from 2 to 83 years (mean = 26.1, SD =  ± 11.8) were participated in this study. The overall seroprevalence of brucellosis was 31.5% (95% CI; 27.4–36.0%) by RBPT and 15.8% (95% CI; 12.7–19.7%) by ELISA, as well as the prevalence of malaria (P. falciparum) was 4.3% (95% CI; 2.7–6.6%) among febrile patients. Malaria was more common in males (7.2% 95% CI; 4.2–12.1%) than in female (2.3% 95% CI; 1.0–5.0%, p = 0.01) and in non-married than in married (7.6% 95% CI; 4.1–13.6% vs. 2.9% 95% CI; 1.5–5.4%, p = 0.02). Being male (AOR = 2.41, 95%CI: 1.36–4.26, p < 0.002), drinking raw milk (AOR = 26.68, 95%CI: 3.22- 221.13, p = 0.002) and boiled milk (AOR = 17.52, 95%CI: 2.06—149.04, p = 0.009) and touching aborted fetus/discharges without protective (AOR = 2.56, 95%CI: 1.01–6.528.50, p = 0.048) were independently associated with brucellosis among febrile patients. Conclusion The prevalence of brucellosis in fever patients in this study area is higher than malaria. Consumption of raw milk and contact with animal discharge can cause significant risk of Brucella infection. So, brucellosis disease must be sought in the differential diagnosis, like ELISA test that can be used to differentiate from other febrile diseases like malaria.

scholarly journals Sero-prevalence and risk factors of human brucellosis among febrile patients visited health institutes at Awra and Gulina district, Afar Region, Ethiopia

2020 ◽  
Author(s):  
Biruk Zerfu ◽  
Sintayehu Mehari ◽  
Kassu Desta
Keyword(s):  
Risk Factors ◽  
Public Health Problem ◽  
Raw Milk ◽  
Cross Sectional Study ◽  
Human Brucellosis ◽  
Sectional Study ◽  
Important Public Health Problem ◽  
Cross Sectional ◽  
Afar Region ◽  
Elisa Data

Abstract Background: Brucellosis is an important neglected bacterial zoonotic disease that affects animals and humans for decades. The aim of this study was to determine the sero-prevalence and risk factors of human brucellosis among febrile patients visited health institutes at Awra and Gulina district of Afar region Ethiopia.Methods: A purposive cross-sectional study was conducted among 444 febrile patients visiting two health institutes in Awra and Gulina district of Afar region from February to May 2019. A 3-5ml blood samples were collected, thick and thin blood films were examined microscopically for malaria; serum was separated and tested antibody of Brucella using Rose Bengal Plate Test (RBPT) and positives ones were further subjected to ELISA. Data were entered using EpiData3.1 and analyses were performed using StataSE 14.Results: A total of 444 febrile individuals (59.5% female) of age ranging from 2-83 years (mean= 26.1, SD = ±11.8) participated in this study. The overall sero-prevalence of brucellosis was 31.5 % and 15.8% by RBPT and ELISA, respectively and 4.3% of the patients were positive for P. falciparum. Being male (AOR=2.41, 95%CI: 1.36 – 4.26, p < 0.002), drinking raw milk (AOR=15.42, 95%CI: 5.17 - 45.95, p < 0.001) and touching aborted fetus/discharges without protectives (AOR= 3.70, 95%CI: 1.61 - 8.50, p = 0.02) were independently associated with brucellosis among febrile patients.Conclusion: Human brucellosis is highly prevalent in pastoralist patients presenting with fever in this study area. Consumption of raw milk and contamination with aborted or discharge of animals are major risk factors. Hence, brucellosis should be considered as an important public health problem in this study area.

scholarly journals Sero epidemiology of Cattle Brucellosis and Associated Risk Factors in Amibara District of Afar Region, Ethiopia

2021 ◽  
Author(s):  
Fekadu Gutema Wegi ◽  
Juhar Tesfaye Bekele
Keyword(s):  
Risk Factors ◽  
Production Systems ◽  
Vaccination Strategy ◽  
Cross Sectional Study ◽  
Economic Problem ◽  
Sample Collection ◽  
Cross Sectional ◽  
Afar Region ◽  
Potential Risk Factors ◽  
Associated Risk Factors

Abstract Bovine brucellosis is the most common but under reported bacterial diseases known to create a serious socio-economic problem in both intensive and extensive livestock production systems. A cross-sectional study was conducted to determine seroprevalence and associated risk factors of cattle brucellosis in Amibara district of Afar region, Ethiopia from October 2019 to May 2020. A total of 181 cattle sera were collected and screened using Rose Bengal Plate Test (RBPT) and reactive samples were further confirmed by complement fixation test (CFT). Risk factors associated with cattle brucellosis were assessed during serum sample collection using data collection format. As a result, the overall seroprevalence of cattle brucellosis was 10.5% and 2.2% by RBPT and CFT respectively. Assessment of potential risk factors showed that, Age (χ2=6.77, p=0.021), number of parity (χ2=9.433, p=0.004), abortion history (χ2=16, p=0.002) and history of placental retention (χ2=19.1, p=0.003) showed statistically significant association with brucellosis seropositivity in cattle. Based on firth’s bias reduced logistic regression analysis, only multiparous animal (OR=10.68, P=0.0042, 95% CI=-1.19-7.595) and animals with placental retention (OR=72.72, P=0.0026, 95% CI=1.46-9.272) showed statistically significantly association with brucella infection in cattle. In conclusion, the results of the current study indicate the presence of brucellosis in cattle in Amibara district of Afar region, Ethiopia. Hence, implementing preventive measures such as developing vaccination strategy, regular screening and culling of the reactive animal is important to create diseases free herd.

scholarly journals Magnitude of spontaneous preterm birth and its associated factors among preterm birth in NICU wards in Asella Teaching and Referral Hospital, Asella, Oromia, Ethiopia

2021 ◽  
Vol 49 (8) ◽  
pp. 030006052110346
Author(s):  
Techane Sisay Tuji ◽  
Addisu Dabi Wake ◽  
Gezahegn Badeg Adere ◽  
Aselefu Beka Wedajo ◽  
Batu Dekeba Obole ◽  
...  
Keyword(s):  
Risk Factors ◽  
Preterm Birth ◽  
Healthcare Providers ◽  
Preterm Births ◽  
Cross Sectional Study ◽  
Spontaneous Preterm Birth ◽  
Related Factors ◽  
Cross Sectional ◽  
Bivariate Logistic Regression ◽  
Associated Risk Factors

Objective To assess the prevalence of spontaneous preterm births and to identify the associated risk factors. Methods This single-centre cross-sectional study enrolled women that experienced a preterm birth as registered on the neonatal log-book between 30 December 2019 and 30 December 2020. A pre-tested structured checklist was used to collect data (sociodemographic characteristics; obstetric-related factors; medical history; and pregnancy-related factors). Bivariate logistic regression analyses were applied to identify factors associated with spontaneous preterm birth. A multivariate model identified significant independent risk factors. Results A total of 310 patients participated in the study. The prevalence of spontaneous preterm birth in this population was 67.1% (208 of 310; 95% confidence interval [CI] 61.5, 71.9). Patients without a partner (adjusted odds ratio [AOR] = 1.470, 95% CI 1.23, 4.42), patients residing in a rural area (AOR = 2.51, 95% CI 1.123, 5.513) and those with a history of PIH during their current pregnancy (AOR = 0.104, 95% CI 0.053, 0.014) were significantly more likely to have a spontaneous preterm birth. Conclusion The prevalence of spontaneous preterm birth in in this study was high. Healthcare providers and all stakeholders should focus on screening pregnant women at the risk of spontaneous preterm birth.

scholarly journals Prevalence of dysmenorrhoea, associated risk factors and its relationship with academic performance among graduating female university students in Ethiopia: a cross-sectional study

BMJ Open ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. e043814
Author(s):  
Mesfin Tadese ◽  
Andargachew Kassa ◽  
Abebaw Abeje Muluneh ◽  
Girma Altaye
Keyword(s):  
Risk Factors ◽  
Academic Performance ◽  
University Students ◽  
Cross Sectional Study ◽  
Secondary Outcome ◽  
Sectional Study ◽  
Cross Sectional ◽  
Grade Point ◽  
Significant Difference ◽  
Associated Risk Factors

ObjectivesThe study aimed to provide an association between dysmenorrhoea and academic performance among university students in Ethiopia. Further, the study attempts to determine the prevalence and associated risk factors of dysmenorrhoea.Design and methodInstitution-based cross-sectional study was conducted from 1 April to 28 April 2019. A semistructured and pretested self-administered questionnaire was used to collect data. Binary logistic regression analysis and one-way analysis of variance were performed to model dysmenorrhoea and academic performance, respectively.Setting and participantsEthiopia (2019: n=647 female university students).OutcomesThe primary outcome is dysmenorrhoea, which has been defined as painful menses that prevents normal activity and requires medication. The self-reported cumulative grade point average of students was used as a proxy measure of academic performance, which is the secondary outcome.ResultsThe prevalence of dysmenorrhoea was 317 (51.5%). The educational status of father (adjusted OR (AOR) (95% CI) 2.64 (1.04 to 6.66)), chocolate consumption (AOR (95% CI) 3.39 (95% 1.28 to 8.93)), daily breakfast intake (<5 days/week) (AOR (95% CI) 0.63 (0.42 to 0.95)), irregular menstrual cycle AOR (95% CI) 2.34 (1.55 to 3.54)) and positive family history of dysmenorrhoea AOR (95% CI) 3.29 (2.25 to 4.81)) had statistically significant association with dysmenorrhoea. There was no statistically significant difference in academic performance among students with and without dysmenorrhoea (F (3611)=1.276, p=0.28)).ConclusionsDysmenorrhoea was a common health problem among graduating University students. However, it has no statistically significant impact on academic performance. Reproductive health officers should educate and undermine the negative academic consequences of dysmenorrhoea to reduce the physical and psychological stress that happens to females and their families.

scholarly journals Occurrence, associated risk factors, and treatment of surgical site infections in Pakistan

2020 ◽  
Vol 18 ◽  
pp. 205873922096054
Author(s):  
Faiz Ullah Khan ◽  
Yu Fang ◽  
Zakir Khan ◽  
Farman Ullah Khan ◽  
Zafar Iqbal Malik ◽  
...  
Keyword(s):  
Risk Factors ◽  
Transurethral Resection ◽  
Surgical Site Infections ◽  
Exploratory Laparotomy ◽  
Cross Sectional Study ◽  
Surgical Patients ◽  
Related Factors ◽  
Cross Sectional ◽  
Mortality And Morbidity ◽  
Associated Risk Factors

Globally, surgical site infections are one of the common infections which lead to a large amount of mortality and morbidity in postsurgical care. The risk for surgical site infection is multidimensional which includes mainly; patient, surgery, and hospital-related factors. This study is aimed to determine the burden of SSIs along with contributed risk factors. A prospective observational cross-sectional study was conducted in one of the largest public-sector hospitals in Pakistan. A total of 412 patients were recruited in the study with full consent and monitored for 30 days after surgery with direct and indirect surveillance. Overall, in seven different surgical procedures the incidence (29.8%) rate of SSI was observed; in appendectomy ( n = 17, 4.1%), exploratory laparotomy ( n = 51, 12.6%), laparoscopic cholecystectomy ( n = 12, 2.90%), mesh repair ( n = 17, 4.01%), thyroidectomy (5, 1.2%), transurethral resection of the prostate ( n = 11, 2.6%), and transurethral resection of the bladder (10, 2.4%). The average SSI rate in every single procedure was about 18 (4.27%) per surgical procedure out of 123 (29.85%) SSI cases. Types of SSI identified were superficial, deep incisional and organ/space ( n = 76, 18.4%, n = 23, 5.5%, and n = 24, 5.7%). Incidence of SSIs during admission, at readmission, and post-surveillance cases were ( n = 50, 12.1%, n = 25, 6.0% and n = 48, 11.6%). Associated risk factors found contributed to the incidence of SSI ( p < 0.05). Pre-operative ( n = 348, 84.5%) and 6 (1.5%) surgical patients did not received the post-operative antibiotics. The P. aeruginosa ( n = 15, 12.1%) and S. aureus (13, 10.5%). Cefoperazone and sulbactam were the most prescribed antibiotics. Associated risk factors and treatment outcomes of surgical patients have a direct association with the incidence of SSI. Hospital-based antimicrobial stewardship, implementation of surgical guidelines, patient care, and education are needed to develop at wards level in hospitals.

scholarly journals Seroprevalence of AsymptomaticLeishmania donovaniamong Laborers and Associated Risk Factors in Agricultural Camps of West Armachiho District, Northwest Ethiopia: A Cross-Sectional Study

2018 ◽  
Vol 2018 ◽  
pp. 1-8
Author(s):  
Animen Ayehu ◽  
Yibeltal Aschale ◽  
Wossenseged Lemma ◽  
Animut Alebel ◽  
Ligabaw Worku ◽  
...  
Keyword(s):  
Risk Factors ◽  
Leishmania Donovani ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
Northwest Ethiopia ◽  
Control Measures ◽  
Sectional Study ◽  
Cross Sectional ◽  
Associated Risk Factors ◽  
Study Participants

Background. Visceral leishmaniasis (VL, also called kala-azar) is a public health problem in Ethiopia, especially in sesame and sorghum growing areas. Compared to other populations, labor migrants are the most exposed. Knowing the seroprevalence ofLeishmania donovaniand associated risk factors is essential to design appropriate control measures. The main aim of this study was to assess the seroprevalence of asymptomaticL. donovaniamong laborers and associated risk factors in agricultural camps of West Armachiho district, Northwest Ethiopia. Therefore, this study was conducted to know the seroprevalence and associated risk factors ofL. donovaniinfection.Method. A cross-sectional study was conducted among 185 laborers from October to December 2017. A simple random sampling technique was used to select study participants from selected agricultural camps. After obtaining written informed consent, data were collected using a structured pretested Amharic version questionnaire using the interview technique. A single finger prick blood sample was collected from the study participants and the blood samples were subjected to the serological diagnostic method using the rk39 kit. The multivariable logistic regression model was used to identify risk factors associated withL. donovaniinfection.Result. Among 185 participants examined using rk39, 14 (7.6%) were seroreactive forL. donovani.Leishmania donovaniinfection had a statistically significant association with sleeping underBalanitestrees (AOR: 4.36, 95%CI: 1.186-16.06), presence of domestic animals near sleeping place (AOR: 4.68, 95% CI: 1.25-17.56), and lack of knowledge about VL transmission (AOR: 3.79, 95% CI: 1.07-13.47).Conclusion. Seroprevalence of asymptomaticL. donovaniamong laborers in agricultural camps of West Armachiho was low. Prevention measures and health education about risk factors that expose toL. donovaniinfection for the laborers are essential to prevent the spread of the disease.

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