Experimental Study on Delivery Performance of an Automated Preloaded Intraocular Lens Injector System for Corneal and Sclerocorneal Incisions

Purpose. To evaluate delivery performance of an automated preloaded intraocular lens (IOL) injector systems (AutonoMe) in the porcine eyes. Methods. In the freshly excised porcine eyes, lens removal and IOL implantation were performed. There were 4 groups (10 eyes per group) with different incision site and size: 2.2-mm and 2.4-mm corneal incisions and 2.2-mm and 2.4-mm sclerocorneal incisions. Delivery performance and wound enlargement of AutonoMe were analyzed and compared with those of iTec and iSert from a previous study. Results. There were a few minor troubles associated with AutonoMe, such as overriding plunger within cartridge and trapped trailing haptic during IOL insertion, but the incidence was low. Other interactions were not observed, such as IOL adherence to plunger, sudden ejection of IOL, intrawound lens manipulation, IOL behavior, and gross damage to IOL. AutonoMe caused significantly less wound enlargement for both corneal and sclerocorneal incisions than other injector devices. Wound enlargement by using AutonoMe was significantly smaller with 2.4-mm corneal incision than with 2.2-mm corneal incision, but the final incision size was still smaller with 2.2-mm corneal incision. For sclerocorneal incisions, the amount of wound stretch was not different between 2.2 and 2.4 mm incisions. Conclusion. The wound enlargement caused by the automated preloaded insertion system, AutonoMe, was smaller than that of other preloaded injectors for both corneal and sclerocorneal incisions. There were a few minor technical events during IOL insertion, but the overall incidence was low.

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Pupil Dilation with Intracameral Epinephrine Hydrochloride during Phacoemulsification and Intraocular Lens Implantation

Journal of Ophthalmology ◽

10.1155/2016/4917659 ◽

2016 ◽

Vol 2016 ◽

pp. 1-5 ◽

Cited By ~ 2

Author(s):

A-Yong Yu ◽

Hua Guo ◽

Qin-Mei Wang ◽

Fang-Jun Bao ◽

Jing-Hai Huang

Keyword(s):

Intraocular Lens ◽

Pupil Diameter ◽

Pupil Dilation ◽

Surgical Performance ◽

Corneal Incision ◽

Iol Implantation ◽

The Mean ◽

Contralateral Eye ◽

To Receive ◽

Time Point

Objective. To investigate mydriatic effect of intracamerally injected epinephrine hydrochloride during phacoemulsification and intraocular lens (IOL) implantation.Methods. Eighteen cataract patients for bilateral phacoemulsification were enrolled. To dilate pupil, one eye was randomly selected to receive intracamerally 1 mL epinephrine hydrochloride 0.001% for 1 minute after corneal incision (intracameral group), and the contralateral eye received 3 drops of compound tropicamide 0.5% and phenylephrine 0.5% at 5-minute intervals 30 minutes before surgery (topical group). Pupil diameters were measured before corneal incision, before ophthalmic viscoelastic device (OVD) injection, after OVD injection, before IOL implantation, and at the end of surgery.Results. At each time point, the mean pupil diameter in the intracameral group was2.20±0.08,5.09±0.20,6.76±0.19,6.48±0.18, and5.97±0.24 mm, respectively, and in the topical group it was7.98±0.15,7.98±0.15,8.53±0.14,8.27±0.16, and7.93±0.20 mm, respectively. The topical group consistently had larger mydriatic effects than the intracameral group (P<0.05). The onset of mydriatic effect was rapid in the intracameral group. There was no difference in surgical performance or other parameters between groups.Conclusions. Intracameral epinephrine hydrochloride appears to be an alternative to the mydriatic modalities for phacoemulsification and IOL implantation. In comparison with topical mydriatics, intracameral epinephrine hydrochloride offers easier preoperative preparation, more rapid pupil dilation, and comparable surgical performance.

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Accuracy of theoretical IOL formulas for Panoptix intraocular lens according to axial length

Scientific Reports ◽

10.1038/s41598-021-86604-5 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Ayoung Choi ◽

Hyunggoo Kwon ◽

Sohee Jeon

Keyword(s):

Intraocular Lens ◽

Axial Length ◽

Mean Absolute Error ◽

Visual Quality ◽

Absolute Error ◽

Fort Worth ◽

Iol Implantation ◽

Multifocal Iol ◽

Study Results ◽

Study Population

AbstractThe accuracy of intraocular lens (IOL) calculations is suboptimal for long or short eyes, which results in a low visual quality after multifocal IOL implantation. The purpose of the present study is to evaluate the accuracy of IOL formulas (Barrett Universal II, SRK/T, Holladay 1, Hoffer Q, and Haigis) for the Acrysof IQ Panoptix TFNT IOL (Alcon Laboratories, Inc, Fort Worth, Texas, United States) implantation based on the axial length (AXL) from a large cohort of 2018 cases and identify the factors that are associated with a high mean absolute error (MAE). The Barrett Universal II showed the lowest MAE in the normal AXL group (0.30 ± 0.23), whereas the Holladay 1 and Hoffer Q showed the lowest MAE in the short AXL group (0.32 ± 0.22 D and 0.32 ± 0.21 D, respectively). The Haigis showed the lowest MAE in the long AXL group (0.24 ± 0.19 D). The Barrett Universal II did not perform well in short AXL eyes with higher astigmatism (P = 0.013), wider white-to-white (WTW; P < 0.001), and shorter AXL (P = 0.016). Study results suggest that the Barrett Universal II performed best for the TFNT IOL in the overall study population, except for the eyes with short AXL, particularly when the eyes had higher astigmatism, wider WTW, and shorter AXL.

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Comparative evaluation of corneal incision enlargement after intraocular lens delivery of new preloaded and manual implantation systems

European Journal of Ophthalmology ◽

10.1177/1120672119882334 ◽

2019 ◽

pp. 112067211988233

Author(s):

Lixin Wang ◽

Patricia Wolfe ◽

Sumit Paliwal ◽

Alexis Chernosky ◽

Thomas Kohnen

Keyword(s):

Delivery System ◽

Intraocular Lens ◽

Standard Of Care ◽

Human Cadaver ◽

Corneal Incision ◽

Eye Model ◽

Incision Size ◽

System P ◽

Wound Recovery

Purpose: To determine whether total corneal incision enlargement after implantation of an intraocular lens with a new preloaded delivery system is comparable to a standard-of-care manual delivery system using an in vitro human cadaver eye model, despite having a smaller initial incision size. Methods: Human cadaver phakic whole eye globes were used for these studies (n = 16 per group). Each pair of eyes was randomly assigned to a new preloaded delivery system (UltraSertTM) or a manual delivery system (MONARCH® III D). The surgical procedure included creating a 2.2- and 2.4-mm corneal incision for the preloaded and manual delivery systems, respectively, measuring intraocular pressure and pre-implantation corneal incision size, delivering the intraocular lens into the anterior chamber, and measuring the post-implantation incision size. Results: The final corneal incision enlargement after intraocular lens delivery using the preloaded delivery system was 2.33 ± 0.04 mm, compared to 2.54 ± 0.05 mm after intraocular lens delivery with the manual delivery system. The mean corneal incision enlargement was comparable between the two systems, being 0.13 ± 0.04 mm using the preloaded delivery system and 0.14 ± 0.05 mm using the manual delivery system (p = 0.432). Conclusion: In a human cadaver eye model, the preloaded delivery system demonstrated an intraocular lens delivery performance on cornea incision enlargement was noninferior to the manual, standard-of-care intraocular lens delivery system despite a smaller initial incision size. Translational relevance: Smaller incision sizes for cataract surgery improve patient outcomes via faster visual and wound recovery and decreased risk of complications such as postoperative inflammation and surgically induced astigmatism.

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Incision size changes after cataract surgery with intraocular lens implantation: comparison of 2 preloaded IOL implantation injectors

Journal of Cataract & Refractive Surgery ◽

10.1097/j.jcrs.0000000000000014 ◽

2020 ◽

Vol 46 (2) ◽

pp. 222-227 ◽

Cited By ~ 1

Author(s):

Suhas S. Haldipurkar ◽

Vijay Shetty ◽

Tanvi Haldipurkar ◽

Rita Dhamankar ◽

Nancy Sehdev ◽

...

Keyword(s):

Cataract Surgery ◽

Intraocular Lens ◽

Intraocular Lens Implantation ◽

Iol Implantation ◽

Incision Size ◽

Lens Implantation

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Clinical and Refractive Outcomes of Different Intraocular lens (IOL) Implantation after Penetrating Keratoplasty (PKP)

POINT OF VIEW EAST – WEST ◽

10.25276/2410-1257-2019-1-47-50 ◽

2019 ◽

pp. 47-50

Author(s):

M.A. Tanash ◽

◽

M.A. Frolov ◽

P.A. Gonchar ◽

L.T. Ababneh ◽

...

Keyword(s):

Intraocular Lens ◽

Penetrating Keratoplasty ◽

Iol Implantation ◽

Refractive Outcomes

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Numerical and Experimental Study of Lightning Stroke to BIPV Modules

Energies ◽

10.3390/en14030748 ◽

2021 ◽

Vol 14 (3) ◽

pp. 748

Author(s):

Xiaoyan Bian ◽

Yao Zhang ◽

Qibin Zhou ◽

Ting Cao ◽

Bengang Wei

Keyword(s):

Numerical Simulation ◽

Experimental Study ◽

Coupling Model ◽

Maximum Temperature ◽

Lightning Stroke ◽

Study Results ◽

Pv Modules ◽

New Type ◽

Metal Frame ◽

Current Flows

Building Integrated Photovoltaic (BIPV) modules are a new type of photovoltaic (PV) modules that are widely used in distributed PV stations on the roof of buildings for power generation. Due to the high installation location, BIPV modules suffer from lightning hazard greatly. In order to evaluate the risk of lightning stroke and consequent damage to BIPV modules, the studies on the lightning attachment characteristics and the lightning energy withstand capability are conducted, respectively, based on numerical and experimental methods in this paper. In the study of lightning attachment characteristics, the numerical simulation results show that it is easier for the charges to concentrate on the upper edge of the BIPV metal frame. Therefore, the electric field strength at the upper edge is enhanced to emit upward leaders and attract the lightning downward leaders. The conclusion is verified through the long-gap discharge experiment in a high voltage lab. From the experimental study of multi-discharge in the lab, it is found that the lightning interception efficiency of the BIPV module is improved by 114% compared with the traditional PV modules. In the study of lightning energy withstand capability, a thermoelectric coupling model is established. With this model, the potential, current and temperature can be calculated in the multi-physical field numerical simulation. The results show that the maximum temperature of the metal frame increases by 16.07 °C when 100 kA lightning current flows through it and does not bring any damage to the PV modules. The numerical results have a good consistency with the experimental study results obtained from the 100 kA impulse current experiment in the lab.

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Surgically induced astigmatism and coupling effect-mediated keratometric changes after conventional phacoemulsification cataract surgery

Spektrum der Augenheilkunde ◽

10.1007/s00717-021-00488-4 ◽

2021 ◽

Author(s):

Reinhard Angermann ◽

Christoph Palme ◽

Philipp Segnitz ◽

Andreas Dimmer ◽

Eduard Schmid ◽

...

Keyword(s):

Cataract Surgery ◽

Coupling Effect ◽

Case Series ◽

Corneal Incision ◽

Surgically Induced Astigmatism ◽

Incision Size ◽

Case Series Study ◽

Induced Astigmatism ◽

Surgically Induced ◽

Phacoemulsification Cataract Surgery

Summary Background The aim of the present study was to describe surgically induced astigmatism (SIA) and the coupling effect after conventional phacoemulsification cataract surgery (CPS) in relation to the incisional axis. Material and methods A total of 42 patients were included in the retrospective case series study. Corneal topography was obtained for patients with significant cataract before and 6 weeks after CPS with a main clear corneal incision size of 2.4 mm. Patients were grouped according to the relationship of the incisional axis to the position of the steep axis into a steep incisional group and a flat incisional group. Results In total, 46 eyes were included in the study. While the steep incisional group showed an SIA of −0.15 D (± 0.35), the flat incisional group had a significantly higher SIA of 0.20 D (± 0.51) (p = 0.03). The coupling ratio (CR) in the steep incisional group was −0.38 (± 1.41) and in the flat incisional group it was 0.16 (± 0.97). Correspondingly, a coupling constant (CC) of −0.25 was found for group 1 and a CC of 0.0 for group 2. Conclusion Our results suggest that the location of the main incision should be decided with consideration of the corneal astigmatism in order to minimize the SIA. The CR helps to understand the effect of induced astigmatism and the change in spherical equivalent.

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