scholarly journals Study on Potential of Meridian Acupoints of Traditional Chinese Medicine

2021 ◽  
Vol 2021 ◽  
pp. 1-16
Author(s):  
Qiuping Li ◽  
Tianxia Zhao ◽  
Xin’an Wang ◽  
Changpei Qiu ◽  
Bing Zhou ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Electric Potential ◽  
Classification Accuracy ◽  
Low Cost ◽  
Principal Component ◽  
Accuracy Rate ◽  
Good Therapeutic Effect ◽  
Acquisition Scheme ◽  
Potential Signal

In recent years, Traditional Chinese Medicine (TCM) has attracted more and more attention due to its good therapeutic effect, low cost, and convenience. This research is also a part of the goal of the modernization of TCM. Based on the meridian electric potential acquisition system independently developed by our project team, in this paper, we designed the human body's meridian electric potential acquisition scheme. We use principal component analysis (PCA) to prove that the meridional potential signal is derived from the ECG signal. Then, Inception ResNet V2 was used to classify acupoints and nonacupoints. Finally, the classification accuracy rate reached 86.59045265, and the F1 score = 0.72161642. This shows that acupoints and nonacupoints can be distinguished by their surface potential.

Opening up a New Field of Modern Medical Research 1

2020 ◽  
Author(s):  
Xiaoguang Li
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Human Body ◽  
Low Cost ◽  
Acupuncture Point ◽  
Modern Medicine ◽  
Body Structure ◽  
Special Effect ◽  
Special Knowledge ◽  
Opening Up

Modern medicine tells us that the human body is an organism composed of heart, lung, liver, kidney, spleen, stomach, brain, nerves, muscles, bones, blood vessels, blood and so on, while traditional Chinese medicine believes that besides these tissues and organs, the human body still has another part of the structure, traditional Chinese medicine calls them Jing Luo and Shu Xue. Jing Luo means the longitudinal line of the human body and the accompanying net, translated into English Meridians and Collaterals. Shu Xue means holes distributed on Jing Luo and outside Jing Luo, because stimulating Shu Xue's position by acupuncture, massage and other methods can cure diseases, so Shu Xue is translated into English acupuncture point, abbreviated as acupoint or point. Meridians and acupoints are the special knowledge of human body structure in traditional Chinese medicine. Traditional Chinese medicine not only draws the distribution map of the meridians and acupoints in the human body, but also has been using them to treat diseases for thousands of years. There are hundreds of these acupoints, stimulating each one by acupuncture, massage or other methods will have a special effect on the human body and can treat various diseases. But what effect does stimulating every acupoint have on the human body so that it can treat various diseases? The discussion of traditional Chinese medicine is vague and incomprehensible, and can not be proved by experiments. According to the author's research for more than 30 years, this paper makes a clear and accurate exposition of the effects on the human body and diseases that can be treated with acupoint massage. These statements can be proved by experiments, so they are believed to be reliable. It is hoped that meridians, acupoints and massage therapy can be incorporated into modern medicine and become a part of modern medicine after being proved by others through experiments. Massaging acupoints can not only treat many diseases that are difficult to be treated with drugs, but also have simple methods and low cost.

scholarly journals Measuring Productivity and Efficiency of Traditional Chinese Medicine Hospitals from 2009 to 2016: A Bootstrap-Data Envelopment Analysis

2021 ◽  
Author(s):  
Xinliang Liu ◽  
Rui Chen ◽  
Shaopeng Wu ◽  
Jian Wang ◽  
Jianan Li ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Total Factor Productivity ◽  
High Efficiency ◽  
Low Cost ◽  
Statistical Significance ◽  
Scale Efficiency ◽  
Productivity Change ◽  
Factor Productivity ◽  
Average Growth

Abstract Objective: It was to estimate the productivity and efficiency of Traditional Chinese Medicine (TCM) hospitals to provide empirical evidence for hospital managers and policy-makers to improve the management and quality of TCM service.Methods: The data of the individual tertiary public TCM hospitals were collected from official Yearbooks of Traditional Chinese Medicine of China (2010-2017). Bootstrap-Malmquist-DEA was employed to measure the productivity and efficiency (2009-2016). SPSS23.0 was used to conduct the descriptive analysis of the input and output indicators. R3.2.1 was applied to calculate the productivity and efficiency with FEAR package. The statistical significance was set at P < 0.05.Results: The annual average growth rates of each indicator were 6.61% (health professionals), 8.15% (actual open beds), 7.08% (outpatients and inpatients) and 12.50% (discharged patients) respectively from 2009 to 2016. Except the total factor productivity change (TFPC) between 2014 and 2015, more than half of the TCM hospitals had TFPC scores over 1.000. The overall annual geo-mean TFPC score was 1.0379.Conclusions: The overall annual rate of the TFPC of the tertiary public TCM hospitals was slightly increased. The technological progress was the main driver to improve the total factor productivity. The decreased technical efficiency was more affected by the decreased scale efficiency. The TCM hospitals need to pay attention to the development and innovation of the TCM technology, thereby improving the competitiveness. The TCM hospitals managers should pursuit the high quality, high efficiency and low cost of the TCM services.

scholarly journals An Integrated Strategy for Effective-Component Discovery of Astragali Radix in the Treatment of Lung Cancer

2021 ◽  
Vol 11 ◽  
Author(s):  
Bing Yang ◽  
Nan Yang ◽  
Yaping Chen ◽  
Maomao Zhu ◽  
Yuanpei Lian ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Signal Pathways ◽  
Therapeutic Effects ◽  
Astragali Radix ◽  
Integrated Strategy ◽  
Effective Components ◽  
Effective Component ◽  
Potential Signal

Lung cancer is one of the most devastating diseases worldwide, with high incidence and mortality worldwide, and the anticancer potential of traditional Chinese medicine (TCM) has been gradually recognized by the scientific community. Astragali Radix (AR) is commonly used in traditional Chinese medicine in the treatment of lung cancer and has a certain clinical effect, but effective components and targets are still unclear. In the study, we established an integrated strategy for effective-component discovery of AR in the treatment of lung cancer based on a variety of techniques. First, the effective components and potential targets of AR were deciphered by the “component-target-disease” network using network pharmacology, and potential signal pathways on lung cancer were predicted by Gene Ontology (GO) biological function enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses. Then, the therapeutic effects of AR in the treatment of lung cancer were evaluated in vivo using A/J mice, and the potential targets related to autophagy and potential signal pathway were verified by Western blot analysis, immunofluorescence staining, and real-time PCR technology at protein and gene expression level. Finally, metabolism in vitro by rat intestinal flora and cell membrane immobilized chromatography technology were used to screen the effective components of AR in the treatment of lung cancer, and remaining components from the cell immobilized chromatography were collected and analyzed by ultra-performance liquid chromatography–electrospray quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS). The screening results of the integrated strategy showed that calycosin-7-O-β-D-glucoside, ononin, calycosin, astragaloside IV, astragaloside II, cycloastragenol, and formononetin may be effective components of AR in the treatment of lung cancer, and they may play a role in the treatment of lung cancer through autophagy and p53/AMPK/mTOR signaling pathway. The integrated strategy for effective-component discovery provided a valuable reference mode for finding the pharmacodynamic material basis of complex TCM systems. In addition, the prediction for targets and signal pathways laid a foundation for further study on the mechanism of AR in the treatment of lung cancer.

Establishment and comparative analysis of HPLC fingerprints of deer tissues

2020 ◽  
Vol 60 (10) ◽  
pp. 1343
Author(s):  
Mengjie Yao ◽  
Haiping Zhao ◽  
Xiaoyan Qi ◽  
Yuan Xu ◽  
Wenyuan Liu ◽  
...  
Keyword(s):  
Principal Component Analysis ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Evaluation System ◽  
High Performance ◽  
Principal Component ◽  
Component Analysis ◽  
Chemometric Methods

Context With the increasing use of velvet antlers (VA) as functional food or traditional Chinese medicine, the quality control has become more and more important. Aims Establish an effective method to provide a way of distinguishing VA from other types of deer tissue. Methods In the present study, 18 samples from three types of deer tissue were analysed on the basis of high-performance liquid chromatography, and a chromatogram of each sample was obtained. Then, these chromatograms were processed using the similarity evaluation system for chromatographic fingerprints of traditional Chinese medicine, to give the fingerprints of three deer tissues. The chemometric methods were used to analyse the fingerprint results, so as to identify the three types of deer tissue. Key results Shared peaks of VA, venison and deer bone were identified using similarity evaluation system. The results showed that, in total, 19 peaks were identified among these three types of deer tissue. Compared with venison, VA lacked three peaks (Numbers 3, 4 and 17); compared with deer bone, VA had six extra peaks (Numbers 2, 5, 8, 9, 14 and 19). The results of chemometric methods showed that different tissue samples could be classified into three categories by using both cluster analysis and principal component analysis. After principal component analysis and partial least-square discrimination analysis, seven peaks were selected, which had significant influence on the classification of VA, venison and deer bone. Conclusions The high-performance liquid-chromatography fingerprints in combination with chemometric methods can be used to effectively distinguish three deer tissue types, namely, VA, venison and deer bone. Implications We believe the method offers a useful tool much needed in the current Chinese velvet market.

scholarly journals Research on Diagnosis Prediction of Traditional Chinese Medicine Diseases Based on Improved Bayesian Combination Model

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Zhulv Zhang ◽  
Jinghua Li ◽  
Wanting Zheng ◽  
Shaolei Tian ◽  
Yang Wu ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Medical Information ◽  
Naive Bayes ◽  
Clinical Decision ◽  
Disease Diagnosis ◽  
Naïve Bayes ◽  
Accuracy Rate ◽  
Intelligent Decision Making ◽  
Bayes Algorithm

Traditional Chinese Medicine (TCM) clinical intelligent decision-making assistance has been a research hotspot in recent years. However, the recommendations of TCM disease diagnosis based on the current symptoms are difficult to achieve a good accuracy rate because of the ambiguity of the names of TCM diseases. The medical record data downloaded from ancient and modern medical records cloud platform developed by the Institute of Medical Information on TCM of the Chinese Academy of Chinese Medical Sciences (CACMC) and the practice guidelines data in the TCM clinical decision supporting system were utilized as the corpus. Based on the empirical analysis, a variety of improved Naïve Bayes algorithms are presented. The research findings show that the Naïve Bayes algorithm with main symptom weighted and equal probability has achieved better results, with an accuracy rate of 84.2%, which is 15.2% higher than the 69% of the classic Naïve Bayes algorithm (without prior probability). The performance of the Naïve Bayes classifier is greatly improved, and it has certain clinical practicability. The model is currently available at http://tcmcdsmvc.yiankb.com/.

scholarly journals Brief Introduction to the Contribution of "Zhouhou Beijifang" to the Emergency Treatment in Traditional Chinese Medicine

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Lan Yao ◽  
Yajun Li
Keyword(s):  
Drug Therapy ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Emergency Surgery ◽  
Emergency Treatment ◽  
Low Cost ◽  
Modern Medicine ◽  
Sublingual Administration ◽  
History Of ◽  
Number Of Treatment

As the first emergency treatment handbook in China, "Zhouhou Beijifang" recorded a large number of treatment methods used in attending to emergencies, and is known for its simplicity, convenience, low-cost and experience. This paper discusses the important value of moxibustion, nasal drug therapy, sublingual administration, emergency surgery and excretion-based drugs in the treatment of emergencies in the book, and discusses its significance and contribution to modern medicine in the history of emergency treatment.

Tanshinone IIA Rapid Analysis of Jingutongxiao Pills by Near-Infrared Spectroscopy

2013 ◽  
Vol 807-809 ◽  
pp. 2075-2078
Author(s):  
Jing Wei Lei ◽  
Hai Yan Gong ◽  
Lei Li ◽  
Cai Xia Xie ◽  
Xiao Yan Duan ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Near Infrared ◽  
Evaluation Method ◽  
Principal Component ◽  
Tanshinone Iia ◽  
Calibration Model ◽  
Analysis Model ◽  
Infrared Spectral ◽  
Traditional Chinese Medicine Preparation

Traditional Chinese medicine(TCM) preparation has a long history in China，and now it is an important direction at the development of hospital preparations, because lacking of quality control technology, quality of the different production batch is not quite stable in the process of production. Therefore, to establish perfect, accurate, rapid quality evaluation method is the key to realize modernization of the traditional Chinese medicine preparation[1,2]. The paper establishes the quantitative analysis model for Tanshinone IIA in Jingutongxiao Pills by near-infrared spectral technology. Through the discussion of spectral wavelength, spectral pretreatment and principal component count, it was found that the second derivative combined with partial least squares (PLS) establishes a best quantitative calibration model. The correlation coefficient of calibration (R2)was 0.975 37, the Root Mean Square Error of Cross Validation (RMSECV) is 0.001 17 and the external prediction deviation (RMSEP) is 0.00174. It indicated that the near-infrared spectral technology could be used for rapid, accurate, nondestructive determination of Tanshinone IIA in Jingutongxiao Pills[3,4].

Green Quantification Strategy Combined with Chemometric Analysis for Triglycerides in Seeds Used in Traditional Chinese Medicine

Planta Medica ◽  
2018 ◽  
Vol 84 (06/07) ◽  
pp. 457-464 ◽  
Author(s):  
Jin-Jun Hou ◽  
Ji-ling Guo ◽  
Chun-Mei Cao ◽  
Shuai Yao ◽  
Hua-li Long ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Principal Component ◽  
Total Content ◽  
Core Shell ◽  
Intermediate Precision ◽  
Limit Of Quantitation ◽  
Medicine Quality ◽  
Single Standard ◽  
Shell Particles

AbstractTriglycerides are the primary constituents of some seed kernels used in traditional Chinese medicine. Quality control of seed kernels containing multiple components with an environmentally friendly method is indispensable for establishing their quality standards (called monographs) in pharmacopeia. Using coix seeds (Semen Coicis) as an example, a green quantification strategy was proposed by combining C8 core-shell particles with single standard to determine multicomponent technologies to quantify seven triglycerides simultaneously. A core-shell column, namely, Halo C8 (3.0 × 100 mm, 2.7 µm), was used. Methanol was used as the mobile phase at a flow rate of 0.3 mL/min, enabling UV detection of the elutes. Seven triglycerides were well separated in 20 min, and simultaneously quantified using triolein as a single standard. The conversion factor for each standard was set as 1.0 on ELSD, while for the conversion factors at 203 nm, the values increased with the reduction of linoleate. The recovery values were all in the range of 97 – 107% (RSD < 3.0%). The RSD values of precision, including intraday and intermediate precision, were < 3.0% when the total content of triglycerides was calculated. The linearity reached r ≥ 0.9990, and the limit of quantitation reached 40 – 70 ng. Forty-nine batches of coix seeds from four different places of origins and eight batches of adulterants were evaluated and differentiated using principal component analysis. In addition, the validated method was used successfully to quantity seven triglycerides in Semen Persicae, Semen Armeniacae Amarum, and Semen Pruni.

scholarly journals Quality Control of Danggui Buxue Tang, a Traditional Chinese Medicine Decoction, byH-NMR Metabolic Profiling

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Pui Hei Chan ◽  
Wendy L. Zhang ◽  
Chi Yuen Cheung ◽  
Karl W. K. Tsim ◽  
Henry Lam
Keyword(s):  
Quality Control ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Metabolic Profiling ◽  
Principal Component ◽  
Chemical Profiling ◽  
Danggui Buxue Tang ◽  
Water Extracts ◽  
Herbal Decoction ◽  
Angelica Sinensis Radix

Danggui Buxue Tang (DBT) is one of the simplest traditional Chinese medicine (TCM) decoctions, first described in China in 1247 AD. DBT is composed of 2 herbs, Astragali Radix (AR) and Angelica Sinensis Radix (ASR), boiled together in a 5 : 1 ratio. Clinically, DBT is prescribed to women as a remedy for menopausal symptoms. Here,H-NMR metabolic profiling was conducted for DBT and the water extracts of AR or ASR, to evaluate the potential of this chemical profiling method for quality control of the herbal decoction. Principal component analysis (PCA) showed that DBT could be readily distinguished from the water extracts of its constituent herbs by the metabolic profiles. More interestingly, the metabolic profile of DBT was not a simple sum of that of AR and ASR. Asparagine was found at significantly higher concentration in DBT than that in either AR or ASR extract, contributing mainly to the discrimination of DBT sample. In addition, we employed the same method to profile a commercial DBT powder, verifying its authenticity as compared to our prepared DBT. This study is the first to employH-NMR metabolic profiling for the quality control of traditional Chinese medicine decoctions.

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