Impact of Alzheimer's Disease in Nine Asian Countries

Gerontology ◽  
2016 ◽  
Vol 62 (4) ◽  
pp. 425-433 ◽  
Author(s):  
Yuan-Han Yang ◽  
Kenichi Meguro ◽  
Sang-Yun Kim ◽  
Yong-Soo Shim ◽  
Xin Yu ◽  
...  

Background: Asia will soon have the majority of demented patients in the world. Objective: To assess dementia using a uniform data system to update the current status of dementia in Asia. Methods: A uniformed data set was administered in Taiwan, China, Hong Kong, Korea, Japan, Philippines, Thailand, Singapore, and Indonesia to gather data with regard to Alzheimer's disease (AD) and its related issues for these countries. Results: In total, 2,370 AD patients and their caregivers were recruited from 2011 to 2014. The demographic characteristics of these patients and the relationships between patients and caregivers were different among individuals in these countries (p < 0.001). Of note, the family history for having dementia was 8.2% for females in contrast to 3.2% for males. Conclusion: Our study highlighted the differences in dementia assessment and care in developing versus developed countries. Greater effort with regard to studying dementia, especially in developing countries, is necessary.

2017 ◽  
Vol 32 (4) ◽  
pp. 194-199 ◽  
Author(s):  
Yuan-Han Yang ◽  
Kenichi Meguro ◽  
Jacqueline Dominguez ◽  
Christopher Li-Hsian Chen ◽  
Huali Wang ◽  
...  

Background: Asia has the greatest population and more patients with dementia in the world. Early recognition of clinical symptoms of Alzheimer’s disease (AD) is crucial for dementia care. In order to foster collaboration in AD care, a uniformed manner to report the early clinical symptoms of AD is necessary. Methods: We have recruited clinically diagnosed patients with AD at their very mild stage with Clinical Dementia Rating (CDR) 0.5 in Taiwan, Japan, China, Philippines, and Singapore. Demographic characteristics and psychometrics including Ascertain of Dementia-8 (AD8) questionnaire were administrated to collect and report the clinical presentation in these countries. Results: In total, 713 clinically diagnosed patients with AD at very mild stage, CDR 0.5, have been recruited from these 5 countries. “Repeats questions, stories, or statements” were consistently the frequently reported symptom across these countries. Taiwan, China, and Singapore have the higher AD8 total score compared to that in Japan and Philippines. Japan and Philippines have the gender-related differences in clinical presentation of early AD. Conclusion: Difficulties in using small trouble appliance and in handling complicated financial affairs were frequently reported in Japan female, compared to male, patients with AD. Identifying the clinical symptom of AD and the gender-related issues would be crucial in the dementia care in Asia.


2014 ◽  
Vol 8 (2) ◽  
pp. 95-98 ◽  
Author(s):  
Mario Alfredo Parra

ABSTRACT Diagnosis of Alzheimer's disease (AD) requires a reliable neuropsychological assessment, but major barriers are still encountered when such tests are used across cultures and during the lifespan. This is particularly problematic in developing countries where most of the available assessment tools have been adapted from developed countries. This represents a major limitation as these tests, although properly translated, may not embody the wealth of challenges that a particular culture poses on cognition. This paper centers on two shortcomings of available cognitive tests for AD, namely, their sensitivity to the educational background and to the age of the individual assessed.


2001 ◽  
Vol 40 (4II) ◽  
pp. 1009-1031 ◽  
Author(s):  
M Arshad Mahmood

Ensuring the survival and well being of children is a concern of families, communities, and nations throughout the world. Since the turn of the 20th century infant and child mortality in more developed countries has steadily declined and, currently, has been reduced to almost minimal levels. In contrast, although infant and child mortality has declined in the past three decades in most less developed countries, the pace of change and the magnitude of improvement vary considerably from one country to another. Children are at risk of both mortality and morbidity. The problem of malnutrition is widespread in developing countries and particularly severe in South Asian countries, where almost fifty percent of the undernourished children of the world live [Carlson and Wardlaw (1990)]. Rural populations are especially prone to malnutrition because they are more likely to be poor [Tinger (1998)]. The analysis of Demographic and Health Surveys (DHS) in 19 developing countries shows that children living in rural areas are more likely to be malnourished [Sommerfelt and Stewart (1994)].


2005 ◽  
Vol 50 (2) ◽  
pp. 393-419 ◽  
Author(s):  
Michaël Segalla

This paper tests a macroeconomic strike model widely used to study the incidence of labour conflict in developed countries on data from the world-at-large. Previous investigations of the influence of labour demand and worker wage expectations on strike frequency have produced contradictory results. Perhaps one reason for this is that these studies have left out all but the most developed countries and have rarely been comparative. This study uses a data set that includes data for 41 countries (approximately half of which are considered developing) from 1953-1985.


2020 ◽  
Vol 13 (2) ◽  
pp. 102-112
Author(s):  
Zois Papadopoulos

: In developed countries, people of advanced age go permanently blind most often due to age-related macular degeneration, while at the global level, this disease is the third major cause of blindness, after cataract and glaucoma, according to the World Health Organisation. The number of individuals believed to suffer from the disease throughout the world has been approximated at 50 million. Age-related macular degeneration is classified as non-neovascular (dry, non-exudative) and neovascular (wet, exudative). The exudative form is less common than the non-exudative as it accounts for approximately 10 percent of the cases of the disease. However, it can be much more aggressive and could result in a rapid and severe loss of central vision. Similarly, with age-related macular degeneration, Alzheimer’s disease is a late-onset, neurodegenerative disease affecting millions of people worldwide. Both of them are associated with age and share several features, including the presence of abnormal extracellular deposits associated with neuronal degeneration, drusen, and plaques, respectively. The present review article highlights the pathogenesis, clinical features, and imaging modalities used for the diagnosis of neovascular age-related macular degeneration. A thorough overview of the effectiveness of anti-VEGF agents as well as of other treatment modalities that have either lost favour or, are rarely used, is provided in detail. Additionally, the common histologic, immunologic, and pathogenetic features of Alzheimer’s disease and age-related macular degeneration are discussed in depth.


2021 ◽  
Vol 12 (4) ◽  
pp. 01-17
Author(s):  
Ana Luisa Chaves Figueira ◽  
Danilo Medeiros Eler ◽  
Celso Olivete Junior

Alzheimer's disease is responsible for 60% of dementia in the world, affecting more than 35 million people, mostly the elderly population over 65 years old. The disease impairs not only memory, but also cognitive skills and emotional control of the patient. Those who contain the disease are not only ones to face this challenge; the family also suffers a lot of wear and tear with the problem. Thus, with the growth of portable and accessible devices, this work aims to present an application named Alzheimer Helper, which helps both an Alzheimer's patient and his family to deal with the disease, so that it is possible for the patient to develop his cognition, train their memory and avoid functional dependence.


1995 ◽  
Vol 34 (4III) ◽  
pp. 1025-1039 ◽  
Author(s):  
Yasmeen Mohiuddln

The purpose of the present paper is to formulate a composite index of the status of women and to rank both developed and developing countries on the basis of that index. This index is presented as an alternative or complement to the current status of women index, published by the Population Crisis Committee (PCC) and used by the World Bank and the United Nations, which focuses on indicators measuring health, education, employment, marriage and childbearing, and social equality. The paper argues that these indicators have a poverty-bias and measure women's status in terms of structural change rather than in terms of their welfare vis-ii-vis men. The PCC index is also based on the implicit assumption that women's status in developing countries ought to be defined in a similar way as in developed countries, thus including primarily only those indicators which are more relevant for developed countries. To remedy these defects, the paper presents an alternative composite index, hereafter labelled the Alternative Composite (AC) index, based on many more indicators reflecting women's issues in both developed and developing countries. The results of the statistical analysis show that the ranking of countries based on the AC index is significantly different from the PCC index.


2020 ◽  
Author(s):  
endang naryono

Covid-19 or the corona virus is a virus that has become a disaster and a global humanitarian disaster began in December 2019 in Wuhan province in China, April 2020 the spread of the corona virus has spread throughout the world making the greatest humanitarian disaster in the history of human civilization after the war world II, Already tens of thousands of people have died, millions of people have been infected with the conona virus from poor countries, developing countries to developed countries overwhelmed by this virus outbreak. Increasingly, the spread follows a series of measurements while patients who recover recover from a series of counts so that this epidemic becomes a very frightening disaster plus there is no drug or vaccine for this corona virus yet found, so that all countries implement strategies to reduce this spread from social distancing, phycal distancing to with a city or country lockdown.


2010 ◽  
Vol 27 (4) ◽  
pp. 23-44
Author(s):  
Ruzita Mohd. Amin

The World Trade Organization (WTO), established on 1 January 1995 as a successor to the General Agreement on Tariffs and Trade (GATT), has played an important role in promoting global free trade. The implementation of its agreements, however, has not been smooth and easy. In fact this has been particularly difficult for developing countries, since they are expected to be on a level playing field with the developed countries. After more than a decade of existence, it is worth looking at the WTO’s impact on developing countries, particularly Muslim countries. This paper focuses mainly on the performance of merchandise trade of Muslim countries after they joined the WTO. I first analyze their participation in world merchandise trade and highlight their trade characteristics in general. This is then followed by a short discussion on the implications of WTO agreements on Muslim countries and some recommendations on how to face this challenge.


2020 ◽  
Vol 27 ◽  
Author(s):  
Kush K. Maheshwari ◽  
Debasish Bandyopadhyay

Background: Neglected tropical diseases (NTDs) affect a huge population of the world and majority of the victims belong to the poor community of the developing countries. Until now, the World Health Organization (WHO) has identified 20 tropical diseases as NTDs that must be addressed with high priority. However, many heterocyclic scaffolds have demonstrated potent therapeutic activity against several NTDs. Objective: There are three major objectives: (1) To discuss the causes, symptoms, and current status of all the 20 NTDs; (2) To explore the available heterocyclic drugs, and their mechanism of actions (if known) that are being used to treat NTDs; (3) To develop general awareness on NTDs among the medicinal/health research community and beyond. Methods: The 20 NTDs have been discussed according to their alphabetic orders along with the possible heterocyclic remedies. Current status of treatment with an emphasis on the heterocyclic drugs (commercially available and investigational) has been outlined. In addition, brief discussion of the impacts of NTDs on socio-economic condition is included. Results: NTDs are often difficult to diagnose and the problem is worsened by the unhealthy hygiene, improper awareness, and inadequate healthcare in the developing countries where these diseases primarily affect poor people. The statistics include duration of suffering, numbers affected, and access to healthcare and medication. The mechanism of actions of various heterocyclic drugs, if reported, have been briefly summarized. Conclusion: Scientists and pharmaceutical corporations should allocate more resources to reveal the in-depth mechanism of actions of many heterocyclic drugs that are currently being used for the treatment of NTDs. Analysis of current heterocyclic compounds and development of new medications can help in the fight to reduce/remove the devastating effects of NTDs. An opinion-based concise review has been presented. Based on available literature, this is the first effect to present all the 20 NTDs and related heterocyclic compounds under the same umbrella.


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