Effect of Omega-3 and Vitamins E + C Supplements on the Concentration of Serum B-Vitamins and Plasma Redox Aminothiol Antioxidant Status in Elderly Men after Strength Training for Three Months

2016 ◽  
Vol 68 (2) ◽  
pp. 145-155 ◽  
Author(s):  
Tonje Holte Stea ◽  
Solvor B. Stølevik ◽  
Sveinung Berntsen ◽  
Nasser Ezzathkah Bastani ◽  
Gøran Paulsen ◽  
...  
Keyword(s):  
Strength Training ◽  
Pyridoxal Phosphate ◽  
Serum Vitamin ◽  
B Vitamins ◽  
Serum Folate ◽  
Omega 3 ◽  
Elderly Men ◽  
Healthy Elderly ◽  
Group I ◽  
Group Ii

Background: Data on redox plasma aminothiol status in individuals on strength training are very limited. Therefore, we studied the effect of omega-3 and vitamins E + C supplementation on the concentration of B-vitamins and redox aminothiol status in elderly men after strength training for 3 months. Methods: Healthy men, age 60 ± 6 (mean ± SD) were randomly divided into 3 groups: group I received placebo (n = 17), group II consumed omega-3 (700 mg, n = 17), and group III consumed vitamins E + C (235 mg +1 g, n = 16) daily for 3 months. All participants completed a strength training program for the same period. Results: The concentration of serum vitamin B12 decreased and the concentration of serum folate increased in group I after the intervention (p = 0.01, p = 0.009). The concentration of plasma 5-pyridoxal phosphate decreased in groups II and III (p = 0.03 and p = 0.01), whereas the concentration of serum uric acid decreased only in group II (p = 0.02). We detected an increase in the concentration of reduced form of aminothiols in all groups (p < 0.001). The red/ox plasma aminothiol status was significantly changed in all groups after the intervention (p < 0.05). Conclusion: Omega-3 and vitamins E + C supplementation affect the concentrations of serum B-vitamins and redox plasma aminothiol status in healthy elderly men on strength training.

scholarly journals Relationship of Maternal Folic Acid and Vitamin B12 with birth weight and body proportion of newborn

2012 ◽  
Vol 18 (1) ◽  
pp. 7-11 ◽  
Author(s):  
Afsana Ahmed ◽  
Mahbooba Akhter ◽  
Shafia Sharmin ◽  
Shamim Ara ◽  
Md Mozammel Hoque
Keyword(s):  
Birth Weight ◽  
Vitamin B12 ◽  
Serum Vitamin ◽  
Maternal Serum ◽  
Serum Folate ◽  
Lower Serum ◽  
Lower Weight ◽  
Group I ◽  
Group Ii ◽  
Folate And Vitamin B12

Vitamin B12 and folate are two important B vitamins that are related to normal fetal development and fetal growth because they act as co-enzyme for the synthesis of nucleic acid and take part in DNA replication and cell division. Reduced level of serum folate and vitamin B12 also results in hyperhomocysteinemia which causes IUGR. A cross sectional study was made in which 150 pregnant women were included according to set inclusion and exclusion criteria of the study. On the basis of anthropometric measurements (birth weight, birth length, OFC) of the newborn, study subjects were grouped into group-I those who delivered low birth weight babies and group-II those who delivered normal birth weight babies. Serum folate and vitamin B12 level were measured in all the study subjects after delivery. Maternal serum folate & vitamin B12 of group-I were significantly lower than that of group-II. Birth weight, length & OFC of newborns showed significant positive correlation with maternal serum folate & vitamin B12. The risk of lower serum folate was significant for lower weight (OR11.00, 95% CI 4.81-25.15), lower length (OR 3.67, 95% CI 1.42-9.47), lower OFC (OR 6.96, 95% CI 2.47-17.87). The risks of lower serum vitamin B12 were significant for lower weight (OR 4.09, 95% CI 1.67-10.00), lower length (OR 4.83, 95%CI 2.28-10.22), lower OFC (OR 4.11, 95%CI 1.97- 8.54). DOI: http://dx.doi.org/10.3329/jdnmch.v18i1.12224 J. Dhaka National Med. Coll. Hos. 2012; 18 (01): 7-11

scholarly journals Systemic inflammation and alteration in vitamin D levels in pregnancy induced hypertension

2014 ◽  
Vol 5 (4) ◽  
pp. 11-15 ◽  
Author(s):  
Dilutpal Sharma ◽  
Rahul Saxena ◽  
Raj Saxena ◽  
Mousumi Sharma ◽  
Alok Milton Lal
Keyword(s):  
Vitamin D ◽  
Systemic Inflammation ◽  
Serum Vitamin ◽  
Pregnancy Induced Hypertension ◽  
Serum Vitamin D ◽  
Sodium Calcium ◽  
Group I ◽  
Vitamin D Levels ◽  
Induced Hypertension ◽  
Group Ii

Background: The increasing incidence of Pregnancy induced hypertension (PIH) or Pre-eclampsia in developed and developing countries are alarming. Systemic inflammation and disturbances in vitamin D and minerals (Sodium & Calcium) metabolism are almost invariable consequences of PIH; and variation in their levels can adversely affect the pregnancy leading to the development of PIH. Aim: In this context, a study was carried out to assess the level of serum vitamin D, sodium, calcium and inflammatory marker C-reactive protein (CRP) in non-pregnant (NP), normotensive pregnant (NTP) and PIH women and to determine their role in the etio-pathogenesis of PIH. Material and method: Serum vitamin D, sodium, calcium and CRP levels were estimated in 20 NTP women (Group I) and 20 PIH women (Group II) by using standard methods and statistically compared it with that of age matched 20 healthy non pregnant women (Control group) by using student’s t-test. Result: Serum Ca++ level were found to be significantly low in both Group I (p<0.05) and Group II (p<0.01) as compared to healthy controls. However, plasma vitamin D levels were decreased insignificantly in Group I (p < 0.1) and significantly (p < 0.05) in Group II patients. Similarly, serum sodium and CRP levels were increased significantly only in Group II patients. Conclusion: Thus, regular assessment of serum CRP, vitamin D, sodium and calcium levels and recommendation of diet low in sodium, rich in calcium and appropriate vitamin D should be increased during pregnancy to prevent PIH and its related complications. DOI: http://dx.doi.org/10.3126/ajms.v5i4.9809 Asian Journal of Medical Sciences 2014 Vol.5(4); 11-15

scholarly journals Effects of Pet Insects on Cognitive Function among the Elderly: An fMRI Study

2019 ◽  
Vol 8 (10) ◽  
pp. 1705 ◽  
Author(s):  
Ji-Yeon Park ◽  
Hae-Jin Ko ◽  
A-Sol Kim ◽  
Ha-Na Moon ◽  
Hye-In Choi ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Elderly Women ◽  
Wisconsin Card Sorting Test ◽  
Community Dwelling ◽  
Positive Effects ◽  
Healthy Elderly ◽  
Insect Rearing ◽  
Group I ◽  
Significant Difference ◽  
Group Ii

Animal-assisted therapy has positive effects on cognitive function, depression, performance ability, and social functioning in elderly patients. The aim of this study was to evaluate the effects of rearing pet insects on the cognitive function of healthy elderly participants, with fMRI (functional magnetic resonance imaging) being used for this purpose. Community-dwelling right-handed elderly women (≥60 years) with normal cognitive function were enrolled and randomized at a 1:1 ratio into two groups: insect-rearing and control (n = 16) groups, with the insect-rearing group being further classified into two groups for analysis according to the subjects’ scores in the Wisconsin Card Sorting Test, WCST) at the baseline fMRI: Insect-rearing group I with a relatively high score (n = 13), and insect-rearing group II with a relatively low score (n = 6). The insect-rearing groups received and reared crickets as pet insects for 8 weeks. The WCST consisted of two variations, a high level baseline (HLB) and semi-WCST version. There was a significant difference accuracy of the HLB–semi-WCST (p < 0.05) in insect-rearing group II after 8 weeks from the baseline test. In the fMRI analysis involving the WCST reaction test, increased activation was observed in the right dorsal lateral prefrontal cortex and parietal cortex in insect-rearing group II when the semi-WCST, rather than the HLB, was performed. Rearing pet insects showed positive effects on executive functions and performance improvement in elderly women. Further larger studies on the effects of pet insects on cognitive function are warranted.

scholarly journals Effects of 12-Week Multivitamin and Omega-3 Supplementation on Micronutrient Levels and Red Blood Cell Fatty Acids in Pre-menopausal Women

2021 ◽  
Vol 8 ◽  
Author(s):  
Shelby C. Osburn ◽  
Paul A. Roberson ◽  
Jessica A. Medler ◽  
Jacob Shake ◽  
Robert D. Arnold ◽  
...  
Keyword(s):  
Vitamin D ◽  
Placebo Group ◽  
Fatty Acid ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Serum Vitamin ◽  
Serum Folate ◽  
Omega 3 ◽  
Serum Vitamin D ◽  
Vitamin D Levels

The purpose of this study was to validate the efficacy of a customized vitamin-mineral supplement on blood biomarkers in pre-menopausal females. Women (21–40 years old) who were apparently healthy were recruited from the local community (ClinicalTrials.gov trial registration NCT03828097). Pretesting (PRE) occurred in the morning 5 ± 2 days following each participant's menses and involved a fasted blood draw, body mass assessment, and blood pressure assessment. Participants were then randomly assigned in a double-blinded fashion to either the multivitamins (MV) (n = 43) or placebo group (n = 51). Participants consumed two capsules per day with breakfast for 12 weeks. Following the trial, participants reported to the laboratory for POST assessments, which replicated PRE procedures. Red blood cell fatty acid and serum micronutrient analyses were performed in a blinded fashion at hematology laboratories. A group × time interaction was observed for serum vitamin D levels (p &lt; 0.001). MV increased levels from PRE to POST (+43.7%, p &lt; 0.001), whereas no change occurred in the placebo group. Additionally, 78% of MV participants at PRE exhibited inadequate vitamin D levels (&lt;40 ng/dl), whereas only 30% exhibited levels below this threshold at POST. An interaction was also observed for serum folate levels (p &lt; 0.001). MV increased serum folate from PRE to POST (p &lt; 0.001), whereas no change occurred in the placebo group. Red blood cell omega-3 fatty acid content increased from PRE to POST in the MV group (p &lt; 0.001) and placebo group (p &lt; 0.05), although POST values were greater in the MV group (p &lt; 0.001). An interaction was observed for serum HDL cholesterol levels (p = 0.047), and a non-significant increase in this variable from PRE to POST occurred in the MV group (p = 0.060). Four-day food recalls indicated MV increased intake of omega-3 fatty acids, vitamin D, folate, and other micronutrients. In summary, MV supplementation increased serum vitamin D, serum folate, and red blood cell omega-3 fatty acid levels. However, these data are limited to healthy females, and more research is needed to examine if MV can affect metabolic disturbances in individuals with micronutrient deficiencies.

scholarly journals Influence of fish oil in the concentration of conjugated linoleic acid and omega 6 and 3 in buffalo milk

2012 ◽  
Vol 64 (2) ◽  
pp. 427-433
Author(s):  
E.M. Patiño ◽  
M.A. Judis ◽  
M. Sanchez Negrette ◽  
D.O. Pochon ◽  
J.F. Cedres ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Fish Oil ◽  
Conjugated Linoleic Acid ◽  
Research Work ◽  
Buffalo Milk ◽  
Omega 3 ◽  
Group Iii ◽  
Group I ◽  
Omega 6 ◽  
Group Ii

The aim of this research work was to investigate the influence of fish oil supplementation on the concentration of conjugated linoleic acid (CLA) and omega 6 and 3 in samples of buffalo milk. A total of 24 female buffaloes separated at random into three groups were fed for 49 days with: natural pasture (group I), supplemented with 70mL of fish oil (group II) and 140mL of fish oil (group III). In the experiment the concentration of CLA showed differences (P<0.05) among the three groups, with a maximum of 7.14mg/g fat in group II. No significant differences were found in omega-6 among the three groups. The highest value of 3.82mg/g fat corresponded to group I, whicht had not been supplemented with fish oil. Significant differences were observed in omega 3 (P<0.05) in groups II and III with respect to group I. The highest average value of 2.42mg/g fat was obtained in group III. The closest relationship omega 6/3 (1.37:1) was observed in group III. As a result, the diets of groups II and III, which included fish oil, increased significantly the content of CLA and omega 3 with reductions in levels of omega 6.

scholarly journals Effects of Pet Insects on Cognitive Function Among the Elderly: An fMRI Study

2019 ◽  
Author(s):  
Ji-Yeon Park ◽  
Hae-Jin Ko ◽  
A-Sol Kim ◽  
Ha-Na Moon ◽  
Hye-In Choi ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Elderly Women ◽  
Community Dwelling ◽  
Animal Assisted Therapy ◽  
Positive Effects ◽  
Healthy Elderly ◽  
Insect Rearing ◽  
Group I ◽  
Significant Difference ◽  
Group Ii

Background: Animal-assisted therapy has positive effects on cognitive function, depression, performance ability, and social functioning in elderly patients. The aim of this study was to evaluate the effects of rearing pet insects on the cognitive function of healthy elderly participants, with fMRI (functional magnetic resonance imaging) being used for this purpose. Methods: Community-dwelling elderly women (&ge;60 years) with normal cognitive function were enrolled during April 2015. They were randomized at a 1:1 ratio into two groups: insect-rearing and control (n=16) groups, with the insect-rearing group being further classified into two groups for analysis according to the subjects&rsquo; scores in the Wisconsin Card Sorting Test, WCST) at the first fMRI: insect-rearing group I with a relatively high score (n=13), and insect-rearing group II with a relatively low score (n=6). All subjects were educated on a healthy lifestyle for better cognitive function at every visit, and the insect-rearing groups received and reared crickets as pet insects. The fMRI was performed at baseline and after 8 weeks using the WCST as a stimulus. The WCST consisted of two variations, a high level baseline (HLB) and semi-WCST version. Results: There were no significant differences in the baseline characteristics among the three groups. There was a significant difference accuracy of the HLB&ndash;semi-WCST (p&lt;0.05) in insect-rearing group II after 8 weeks from the baseline test. In the fMRI analysis involving the WCST reaction test, increased activation was observed in the right dorsal lateral prefrontal cortex and parietal cortex in insect-rearing group II when the semi-WCST, rather than the HLB, was performed. There were no significant differences in the other groups. Conclusion: The rearing of pet insects as an animal-assisted therapy is cost-effective, easy, and occupies little space. In this study, it showed positive effects on executive functions and performance improvement in elderly women. Further larger studies on the effects of pet insects on cognitive function are warranted.

scholarly journals Comparison of Vitamin D Level among Vaccinated and Non Vaccinated Pregnant Women with Covid-19

2021 ◽  
Vol 15 (10) ◽  
pp. 3500-3502
Author(s):  
Saeeda Safi ◽  
Umme habiba ◽  
Shandana Mustafa Jadoon ◽  
Umbreen Idrees ◽  
Ayesha Aftab ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Vitamin D ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Body Mass ◽  
Gestational Age ◽  
Serum Vitamin ◽  
Serum Vitamin D ◽  
Group I ◽  
Group Ii

Objective: The aim of this study is to compare the vitamin D level among vaccinated and non-vaccinated pregnant women with COVID-19. Study Design: Observational/comparative study Place and Duration: The study was conducted at the department of Gynae and Obs Quaid-e-Azam International Hospital, Islamabad and Qazi Hussain Ahmad Medical Complex, Nowshera for Duration of six months from October 2020 to March 2021. Methods: Total 120pregnant women had coronavirus disease were presented. Informed written consent was taken for details demographics age, gestational age, parity and body mass index. 18-45years was the women ages. Patients were categorized into 2-groups. Group I had 60 vaccinated patients and in group II 60 non-vaccinated pregnant women. Blood sample of all the patients were taken for the level of serum 25-hydroxy vitaminD3 [25 (OH) D3]. Vitamin D deficiency was calculated and compared among both groups. Sufficient serum vitamin D level was considered >30ng/ml. SPSS 23.0 version was used to analyze complete data. Results: In group I age was 28.4±8.55 years with mean BMI 24.08±1.18 kg/m2 and in group II age was 27.41±6.37 years with mean body mass index 23.12±4.42 kg/m2. Mean gestation age in group I was 33.12±9.42 weeks and in group II mean gestational age was 34.07±5.63 weeks. Mean parity in group I was 3.88±7.27 and in group II 4.01±4.14 was mean parity. We found 28 (46.7%) primigravida cases in I-group and 30 (50%) primigravida females in II-group. In group I 51(85%) patients had vitamin D deficiency and in group II 54 (90%) had deficiency of vitamin D. Among 51 deficient women of group I, number of severe deficiency (<10ng/ml) women were 8 (13.3%), deficiency (10-20ng/ml) were 13 (21.7%) and not-sufficient (20-30ng/ml) were 30 (50%) and in group II prevalence of severity (<10ng/ml) patients were 10 (16.7%), deficient cases (10-20ng/ml) were 15 (25%) and not-sufficient cases (20-30ng/ml) were 29 (48.3%). Deficient vitamin D serum levels were 15.01±1.22 in group I and 14.34±4.12 in group II. Conclusion: In this study we concluded that prevalence of vitamin D deficiency was highly among pregnant women and most probably in non-vaccinated pregnant patients but did not find any significantly difference among both groups. Keywords: Pregnancy, COVID-19, Vitamin D, Vaccination

Procoagulant Activity and Cytokine Expression in Whole Blood Cultures from Patients with Atherosclerosis Supplemented with Omega-3 Fatty Acids

1999 ◽  
Vol 81 (04) ◽  
pp. 566-570 ◽  
Author(s):  
Ingebjørg Seljeflot ◽  
Odd Johansen ◽  
Harald Arnesen ◽  
Jan-Bertil Eggesbø ◽  
Åse-Britt Westvik ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Whole Blood ◽  
Inflammatory Responses ◽  
Cytokine Expression ◽  
Blood Cultures ◽  
Procoagulant Activity ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Group I ◽  
Group Ii

SummaryOmega-3 fatty acids (n-3 FA) may reduce atherogenesis and thrombosis. We investigated the effects of n-3 FAs on procoagulant activity and cytokine expression in whole blood cultures from patients with atherosclerosis. Eleven of the 23 included patients had received 5.1 g n-3 FA daily for 6 months (group I) whereas 12 patients had been on placebo (group II). All patients were then given 5.1g n-3 FA daily for another 4 weeks.At baseline significantly lower levels of LPS-induced prothrombin fragment1+2 were found in group I (p = 0.010), this difference being eliminated after 4 weeks. Il-6 and TNFαwere significantly higher at baseline in group I and the differences in changes from baseline between the groups were statistically highly significant with increasing values in group II (Il-6 p = 0.001, TNFαp = 0.002).The present results indicate a reduction in pro-thrombotic potential in patients receiving highly concentrated n-3 FA, whereas some pro-inflammatory responses might be adverse.

scholarly journals Effect of vitamin D on women’s somatic and reproductive health

2020 ◽  
pp. 268-273
Author(s):  
I. G. Zhoukovskaya ◽  
I. R. Yakupova
Keyword(s):  
Vitamin D ◽  
Reproductive Health ◽  
Women’S Health ◽  
Women's Health ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Serum Vitamin D ◽  
Group I ◽  
Vitamin D Levels ◽  
Group Ii

The article presents the results of a study of the effect of vitamin D deficiency on women’s health.The study aimed to determine the prevalence of vitamin D deficiency and its relationship with the somatic and reproductive health of women.Methods: observation group I included 31 women with a reduced serum vitamin D levels (20.4 ± 1.0 ng/ml), comparison group II included 31 patients with normal vitamin D levels (39.0 ± 1.4 ng/ml). Results: the negative effect of vitamin D deficiency on women’s health is also practically assured, i.e. the incidence of somatic pathology is significantly higher in group I compared with group II: obesity (62.5 ± 12.1% and 18.8 ± 9.8%; p <0.5), insulin resistance (55.0 ± 9.0% and 1.0 ± 6.0%; p <0.001); arterial hypertension (42.0 ± 8.8% and 13.0 ± 6.0%; p <0.01); hypertrophic myocardiopathy (25.8 ± 7.8% and 6.4 ± 4.4%; p <0.05); chronic colitis (29.0 ± 8.1% and 6.4 ± 4.4%; p <0.05), gastric ulcer (22.5 ± 7.5% and 3.2 ± 3.2%; p <0.05), chronic pancreatitis (22.5 ± 7.5% and 3.2 ± 3.2%; p <0.05), chronic gastritis (25.8 ± 7.8% and 9.7 ± 5.3%; p <0.1). The interaction between reduced vitamin D levels and reproductive system diseases is confirmed by significant increase in the prevalence of secondary amenorrhea (80.0 ± 9.0% and 16.0 ± 7.3%; p <0.001), secondary oligomenorrhea (75.0 ± 9.7% and 20.0 ± 8.0%; p <0.001), hyperplastic processes – uterine fibroids (48.4 ± 9.0% and 13.3 ± 6.1%; p <0.001) and adenomyosis (26.6 ± 7.9% and 6.7 ± 4.5%; p <0.05), polycystic ovary syndrome (29.0 ± 8.2% and 6.7 ± 4.5%; p <0.05), vaginal microbiocenosis disorders (aerobic vaginitis – 42.0 ± 8.9% and 16.1 ± 6.6%; p <0.05; bacterial vaginosis – 29.0 ± 8.2% and 9.7 ± 5.3%; p <0.05).Conclusion: management of vitamin D level is one of the priorities in the formation of therapeutic and preventive measures to improve the women’s health.

scholarly journals Association of Serum Vitamin D Levels with Senile Cataract

2020 ◽  
Vol 36 (3) ◽  
Author(s):  
Yasir Iqbal Malik ◽  
Aqsa Malik ◽  
Atteya Zaman ◽  
Rabia Shabbir ◽  
Masooma Talib
Keyword(s):  
Vitamin D ◽  
Serum Vitamin ◽  
Senile Cataract ◽  
P Value ◽  
Serum Vitamin D ◽  
Age Related ◽  
Group I ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
Group Ii

Purpose: To determine vitamin D levels in patients of senile cataract and compare them with age related controlpatients.Study Design: Case control observational study.Place and Duration of Study: Naseer Memorial Hospital, Dadhyal Azad Kashmir from March 2016 to June2017.Material and Methods: Three hundred patients were selected and two groups were designed for the study.Group I included patients having senile cataract of any morphological type. The inclusion criteria were age of 50years or more. Group II was control in which age matched controls that had no cataract were enrolled from theoutpatient clinic. Vitamin D levels were measured by radioimmunoassay technique with Diasorin SR® kit followingthe user’s manual. The collected data was entered in the statistical package for social sciences (SPSS) version21 for analysis. Independent t –test was used to determine the significant difference of means between controlsand patients. P value less than 0.05 was considered as significant.Results: Group I consisted of 65.33 % females and 35.66% males whereas in group II were 68% females and32% males. The mean age of patients was 63.20 ± 9.5 years in group I and 65.5 ± 8.9 years in group II.Statistically no significant difference (p>0.05) was found between mean Vitamin D levels in cataract patients(25.95 ± 3.75 ng/mL vs. and age matched control (29.02 ± 5.11ng/mL).Conclusion: There was no statistically significant difference between the vitamin D levels of cataract patientsand the age matched controls

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