Prevalence of Hypersensitivity in Teeth Affected by Molar-Incisor Hypomineralization (MIH)

2019 ◽  
Vol 53 (4) ◽  
pp. 424-430 ◽  
Author(s):  
Fernanda Raposo ◽  
Ana Cristina de Carvalho Rodrigues ◽  
Érica Negrini Lia ◽  
Soraya Coelho Leal

Aim: This study aimed to investigate the prevalence of hypersensitivity in molar-incisor hypomineralization (MIH)-affected molars through a census carried out in 8-year-old schoolchildren. Methods: Examinations were conducted by a calibrated examiner, using the Nyvad criteria for caries diagnosis and a new criterion for MIH assessment. For hypersensitivity assessment, all MIH-affected molars were included. Nonaffected molars from the same child were used as controls. Air blast reaction was measured using the Visual Analogue Scale (VAS) and the Schiff Cold Air Sensitivity Scale (SCASS) scale, while tactile hypersensitivity was scored using VAS only. Statistical analysis was performed using the Kruskal-Wallis test followed by Dunn’s multiple comparisons test for quantitative data. χ2 was used for the comparison of categorical data. Results: In total, 631 children were assessed, of whom 102 had MIH-affected molars (16.1%). Of these, 51.7 and 8.7% presented enamel and dentin carious lesions, respectively. Regarding the number of teeth, 239 molars were MIH affected (59.8%), with 188 (78.7%) being classified as mild (opacities only), 20 (8.4%) as moderate (posteruptive enamel breakdown), and 31 (13%) as severe (posteruptive breakdown involving dentin/atypical restorations). Hypersensitivity was recorded in only one control molar, while the prevalence of hypersensitivity in MIH-affected molars was 34.7%, being of low intensity and more prevalent in moderate (55%) and severe cases (51.6 %) than in mild cases (29.8%, p = 0.008). An association between hypersensitivity and the presence of mild and moderate cases was observed. Although the same association was observed for severe cases, it was not considered a reliable information as 90% of the MIH-affected molars with posteruptive breakdown involving dentin were affected by carious lesions. It is known that dental caries is a confounding factor for the presence of hypersensitivity. Conclusions: Hypersensitivity was significantly higher in MIH-affected molars than in nonaffected molars, being associated with MIH teeth presenting opacities and posteruptive enamel breakdown.

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Thomas Linner ◽  
Yeganeh Khazaei ◽  
Katharina Bücher ◽  
Jan Pfisterer ◽  
Reinhard Hickel ◽  
...  

AbstractTooth hypersensitivity is a common symptom in patients with molar-incisor hypomineralization (MIH). Therefore, this clinical study aimed to assess potential associations between patient- and tooth-related variables and the intensity of hypersensitivity in MIH-affected permanent teeth compared to healthy controls. Fifty-seven MIH patients and 20 healthy adolescents with a total of 350 MIH-affected and 193 healthy teeth were included in this study. The intensity of hypersensitivity was measured after cold air stimulation using the Schiff Cold Air Sensitivity Scale (SCASS) by the dentist and visual analogue scale (VAS) by the patient. Tooth hypersensitivity was low in non-MIH teeth (97.9% of the group had zero SCASS and VAS values). In contrast, MIH-affected teeth with demarcated opacities and atypical restorations had moderate SCASS and VAS values, whereas teeth with enamel breakdown were mostly linked to severe hypersensitivity. The logistic regression model confirmed a significantly lower level of hypersensitivity in MIH patients aged ≥ 8 years (OR 0.06, 95% CI 0.01–0.50, p = 0.009) and higher levels in molar teeth (OR 5.49, 95% CI 1.42–21.27, p = 0.014) and teeth with enamel disintegration (OR 4.61, 95% CI 1.68–12.63, p = 0.003). These results indicate that MIH-related tooth hypersensitivity seems to be present in disintegrated molars immediately after tooth eruption.


Author(s):  
Carmen Llena ◽  
Elena Calabuig ◽  
José Luis Sanz ◽  
Maria Melo

The aim of this study was to evaluate the risk factors associated with the occurrence of caries in permanent teeth (PT) and in the permanent first molar (PFM) seven years after their eruption. Children born in 2005 who were enrolled in a Community Dental Program were included. A total of 278 children were enrolled. Evaluated risk factors were parental caries experience, educational level of the mother, routine medications, systemic diseases, dietary habits, toothbrushing frequency, existence of molar incisor hypomineralization (MIH) in the PT, and caries in the temporary teeth (TT). Associations between independent variables and the DMF-T (decayed, missing, and filled teeth in PT) and DMF-M (DMF in PFM) indices, only considering cavitated and non-cavitated carious lesions or cavitated carious lesions as outcomes, were evaluated by Poisson regression with robust variance analysis. A cariogenic diet (sweets and soft drinks), toothbrushing frequency of <1 a day, a presence of df-t (decayed and filled temporary teeth) score of >0, low educational level of the mother, and existence of MIH were associated with high DMF-T or DMF-M values (p < 0.05). We can conclude that the intake of sweets and soft drinks, toothbrushing frequency, the presence of caries in TT, and MIH in PT were the best predictors of the occurrence of caries in PT and PFM.


1986 ◽  
Vol 20 (3) ◽  
pp. 350-359 ◽  
Author(s):  
Wayne Hall ◽  
Kevin D. Bird

Methods are outlined for performing simultaneous multiple comparisons between groups when the dependent variable is one in which subjects are assigned to one of two or more categories. These methods provide tests which are analogous to Scheffe- and Bonferroni-adjusted tests of contrasts in the analysis of variance. Examples are provided of each of these procedures.


2021 ◽  
Vol 55 (1) ◽  
pp. 1-11
Author(s):  
Stefania Martignon ◽  
David Bartlett ◽  
David J. Manton ◽  
E. Angeles Martinez-Mier ◽  
Christian Splieth ◽  
...  

Non-carious dental lesions such as developmental defects of enamel (DDE) and erosive tooth wear (ETW) are the subject of intensive research. This paper aims to give perspectives on both DDE, including dental fluorosis and molar incisor hypomineralization (MIH), and ETW, presenting epidemiological data from the Americas and associated diagnostic aspects. Besides, it is important to present evidence to guide the clinical assessment process, supporting the clinicians’ management decisions towards better oral health of their patients. The overall increase in the worldwide prevalence of non-carious lesions discussed in this this paper may reflect the need of perceptual changes. Although the number of publications related to these conditions has been increasing in the last years, there is still a need for clinical diagnostic and management awareness to include these conditions in routine dental practice. Besides, it is important to provide recommendations for standardized clinical assessment criteria, improving the process and helping clinicians’ adherence. In this sense, this paper discusses the most commonly implemented indices for each condition. Thus, despite the wide range of diagnostic indices, BEWE is proposed to be the index recommended for ETW assessment, Dean or Thylstrup &amp; Fejerskov indices for fluorosis and preferably the EAPD criteria (or modified DDE index) for MIH. Overall, non-carious lesions are a growing concern, and it is important to implement preventive measures that control their severity and progression, and accurate diagnosis by the dental clinician.


2018 ◽  
Author(s):  
David Lazarus ◽  
Johan Renaudie ◽  
Dorina Lenz ◽  
Patrick Diver ◽  
Jens Klump

Acquiring data on the occurrences of many types of difficult to identify objects are often still made by human observation, e.g. in biodiversity and paleontologic research. Existing computer counting programs used to record such data have various limitations, including inflexibility and cost. We describe a pair of new open-source programs for this purpose - Raritas and RaritasVox, which share a similar graphical user interface for mouse based counting, and file output format. Raritas is written in Python and can be run as a standalone app for recent versions of either MacOS or Windows, or from the command line as easily customized source code. RaritasVox in addition supports voice based counting but is written in Java and is more complex to install or modify. Both programs explicitly support a rare category count mode which makes it easier to collect quantitative data on rare categories, e.g. rare species which are important in biodiversity surveys. Lastly, as to our knowledge no standards exist yet, we describe a new stratigraphic occurrence data (SOD) unitary file format which combines extensive metadata and a flexible structure for recording occurrence data of species or other categories in a series of samples.


2021 ◽  
Vol 11 ◽  
Author(s):  
Chuanjun Liu ◽  
Jiangqun Liao

Recently, a multinomial process tree model was developed to measure an agent’s consequence sensitivity, norm sensitivity, and generalized inaction/action preferences when making moral decisions (CNI model). However, the CNI model presupposed that an agent considers consequences—norms—generalized inaction/action preferences sequentially, which is untenable based on recent evidence. Besides, the CNI model generates parameters at the group level based on binary categorical data. Hence, the C/N/I parameters cannot be used for correlation analyses or other conventional research designs. To solve these limitations, we developed the CAN algorithm to compute norm and consequence sensitivities and overall action/inaction preferences algebraically in a parallel manner. We re-analyzed the raw data of the original CNI model to test the methodological predictions. Our results demonstrate that: (1) the C parameter is approximately equal between the CNI model and CAN algorithm; (2) the N parameter under the CNI model approximately equals N/(1 − C) under the CAN algorithm; (3) the I parameter and A parameter are reversed around 0.5 – the larger the I parameter, the more the generalized inaction versus action preference and the larger the A parameter, the more overall action versus inaction preference; (4) tests of differences in parameters between groups with the CNI model and CAN algorithm led to almost the same statistical conclusion; (5) parameters from the CAN algorithm can be used for correlational analyses and multiple comparisons, and this is an advantage over the parameters from the CNI model. The theoretical and methodological implications of our study were also discussed.


Author(s):  
Janet L. Peacock ◽  
Philip J. Peacock

Why summarize data? 174 Types of data 176 Quantitative data 178 Categorical data 180 Summarizing quantitative data 182 Calculation of mean, SD 184 Calculation of median, interquartile range 186 Geometric mean, harmonic mean, mode 188 Choosing a summary measure for quantitative data 190 Summarizing categorical data ...


Author(s):  
Paul Cleary ◽  
Sam Ghebrehewet ◽  
David Baxter

This chapter provides a grounding in basic statistics, descriptive epidemiology, analytical epidemiology, and hypothesis testing appropriate for health protection practitioners. The analysis of categorical data using frequency distributions, and charts, and the interpretation of epidemic curves is described. The description of quantitative data including central tendency, standard deviation, and interquartile range is concisely explained. The role of geographical information systems and different disease map types is used to demonstrate how disease clusters may be detected. Determining possible association between specific risk factors and outcome is described in the section on analytical epidemiology, using the risk ratio and the odds ratio. The use of these in different study/investigation types is explained. The importance of confounding, matching, and standardization in study design is described. The final part of the chapter covers hypothesis testing to distinguish between real differences and chance variation, and the use of confidence intervals.


2014 ◽  
Vol 39 (5) ◽  
pp. E186-E194 ◽  
Author(s):  
CRG Torres ◽  
TM Silva ◽  
BM Fonseca ◽  
ALLS Sales ◽  
P Holleben ◽  
...  

SUMMARY The aim of this study was to evaluate the efficacy of three desensitizing agents to provide relief to dentin hypersensitivity after one session in a four-week follow-up. Forty selected patients participated in a double-blind study following a split-mouth model. One application of the desensitizing agents (A, Admira Protect [Voco]; B, Bifluorid 12 [Voco]; and C, Colgate Pro-Relief in office [Colgate Palmolive]) was performed in three different quadrants for each patient. Each tooth was evaluated by tactile and evaporative stimuli, and the sensitivity response was measured using the Visual Analogue Scale. Evaluations were performed at baseline, immediately after treatment, and after one, two, three, and four weeks. The application of Kruskal-Wallis and Dunn multiple comparisons tests (5%) for both tactile and evaporative stimuli showed that all agents presented a significant desensitizing effect. In groups A and B this relief was maintained for four and three weeks, respectively, as measured by tactile stimulus and for four weeks with evaporative stimulus. The desensitizing effect for group C was maintained for two weeks for both tactile and evaporative stimuli. It is concluded that all desensitizing agents tested were effective in reducing sensitivity compared to baseline values. One application of Admira Protect and Bifluorid 12 presented a longer-lasting desensitizing effect than did Colgate Pro-Relief (applied in the office) on both tactile and evaporative stimuli.


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