Right-to-Left Shunt and the Clinical Features of Migraine with Aura: Earlier but Not More

Background: The causal relationship between patent foramen ovale (PFO) and migraine with aura (MA) is controversial. We aimed at exploring whether attack clinical features relate to the presence of right-to-left shunt (RLS) in MA patients. Methods: We retrospectively examined a cohort of consecutive patients diagnosed with MA in our headache center and undergoing transcranial doppler (TCD) for RLS detection. We collected from our clinical electronic dossiers, clinical features of MA attacks (type, frequency, duration of aura phenomenon, trigger factors, onset age), family history for MA, thrombophilia genotypes, and the response to preventive treatments. RLS was stratified for severity according to the results of the TCD examination. Results: We found 111 patients. Binary logistic regression analysis showed that among features of MA attacks, only onset age was associated with the presence of RLS (p < 0.0001). Patients with RLS presented the first MA attack at a younger age (p < 0.0001). The greater RLS severity, the younger was onset age (p < 0.00001) and the presence of atrial septal aneurysms (ASA) was associated with a further decrease in onset age (ρ = –539, p < 0.00001). Family history for MA was associated with the presence of RLS (chi-square p = 0.022). Response to preventive treatments was not influenced by the type of treatment (antiplatelet compared with no antiplatelet drugs), comorbidity with migraine without aura, RLS presence, or by their double interactions (Logistic regression, consistently p > 0.05). Conclusion: Our findings support the hypothesis that although PFO does not influence MA attack frequency, it is not merely a bystander in MA physiopathology, as RLS, its severity, and the presence of ASA possibly make a difference in the disease history.

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DETERMINANTS OF INCOME SECURITY AMONG PENSIONABLE RETIRED PERSONS IN KENYA

Chemchemi International Journal of Humanities and Social Sciences ◽

10.33886/cijhs.v11i1.139 ◽

2020 ◽

Vol 11 (1) ◽

pp. 24-34

Author(s):

Lucy Maina ◽

Elishiba Kimani

Keyword(s):

Logistic Regression ◽

Binary Logistic Regression ◽

Binary Logistic Regression Analysis ◽

Retirement Savings ◽

Chi Square ◽

Income Security ◽

Financial Status ◽

Chi Square Test ◽

Test Of Significance ◽

Logistic Regression Procedure

Retirees’ income security constitutes a key concern for nations aiming to secure their ageing populations. Kenya has a growing retirement sector with about 252,000 retired civil servants who are on pension and a significant number of private sector retirees who receive a gratuity at retirement. Though formally retired workers may receive a pension, studies consistently report low pensions uptake and inadequate incomes for those retired as well as an increasing national and societal burden. This paper explores the key determinants of income security among 978retired persons who were receiving dues on their retirement savings. Guided by the life cycle and third age theory, the study investigated whether retirees’ socio-economic attributes, pre-retirement financial status, retirees’ benefit package, retirees’ utilization of retirement savings and investments and pre-retirement preparation correlated with income security. A mixed-method study design was used combining survey and case study approaches. Cluster, purposive and random sampling methods were employed to select retirees under the four categories of retirement schemes in Kenya across 18 selected counties of Kenya. Hypotheses were tested using the Chi square test of significance and comparison of means (t-test) specifically to illustrate the relationship between socio-economic indicators, pre-retirement factors and income security at retirement. Logistic regression procedure was employed to isolate the significant factors that predict income security in retirement. The binary logistic regression analysis confirm that retirees with higher education had 26% higher chances of enjoying income security, those who earned higher pre-retirement salary had 25% higher chances of having a secure income at retirement, those knowledgeable about pensions had 35% higher chances of being income secure while those who had planned for their retirement had 14% higher chances of achieving income security. The study recommends crafting of a robust retirement planning package, financial and health plans for retirees’ income security and sustainable livelihoods.

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Age at First Conception and its Determinants of Ever-Married Women in Bangladesh

International Journal of Scientific Research and Management ◽

10.18535/ijsrm/v9i8.sh03 ◽

2021 ◽

Vol 9 (08) ◽

pp. 683-395

Author(s):

Mohammad Manjur Alam

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Logistic Regression Analysis ◽

Binary Logistic Regression ◽

Married Women ◽

Binary Logistic Regression Analysis ◽

Demographic And Health Surveys ◽

Chi Square ◽

Reproductive Process ◽

Chi Square Tests

Age at first conception is an important part of the reproductive process that identifies the level of fecundability and indicative fertility during the early stages of marriage. This study explores the age at first conception and its determinants of ever-married women in Bangladesh by extracting the recent Bangladesh Demographic and Health Surveys (BDHS 2017) data. Descriptive statistics, ANOVA, chi-square tests, and binary logistic regression analysis were carried out to analyze data. Overall, the mean age at first conception of Bangladeshi women is 17.82 ± 3.29 years with significant variations by different socio-demographic, cultural, and behavioral factors. Bivariate analysis of chi-square tests shows that all the independent variables have a significant effect on age at first conception. The finding of the binary logistic regression analysis revealed that respondents' current age, age at first cohabitation, respondents' education, and partners' education are the most important determinants of age at first conception in Bangladesh. Moreover, secondary (OR= 0.743, 95% CI = 0.622- 0.886, P < 0.01) and higher educated women (OR= 0.838, 95% CI = 0.710- 0.989, P < 0.05) were respectively less likely to having first conception at age above 17.25 years, compared to no educated women. Thus, to increase the age at the first conception and reduce the level of fertility, it is necessary to increase the age at the first marriage of the respondents and the level of education for both partners.

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Aicardi Syndrome: Key Fetal MRI Features and Prenatal Differential Diagnosis

Neuropediatrics ◽

10.1055/s-0040-1710528 ◽

2020 ◽

Vol 51 (04) ◽

pp. 276-285

Author(s):

Doneda Chiara ◽

Izzo Giana ◽

Silvia Masnada ◽

Formica Manuela ◽

Scarabello Marco ◽

...

Keyword(s):

Logistic Regression ◽

Differential Diagnosis ◽

Fetal Mri ◽

Binary Logistic Regression ◽

Binary Logistic Regression Analysis ◽

Chi Square ◽

Predictive Variables ◽

Mri Features ◽

Significant Difference ◽

Aicardi Syndrome

Abstract Objective This study was aimed to investigate the prenatal findings in Aicardi syndrome (AIC) by intrauterine magnetic resonance imaging (iuMRI) suggesting possible diagnostic criteria and differential diagnosis. Methods The iuMRI features of nine AIC confirmed cases were described and then compared with those of postnatal MRI. Furthermore, all iuMRI cases with both corpus callosum (CC) agenesis–dysgenesis and cortical malformation (AIC mimickers) were retrospectively reviewed and compared with iuMRI AIC cases, in order to identify possible neuroradiological predictors of AIC syndrome. For this purpose, Chi-square statistic and binary logistic regression analysis were performed. Results In all AIC cases, iuMRI was able to detect CC agenesis–dysgenesis and cortical development anomalies. Postnatal MRI revealed some additional findings mainly including further cystic lesions and in two cases small coloboma. A statistically significant difference between AIC and AIC mimicker were found regarding sex, nodular heterotopias, posterior fossa abnormalities, coloboma, and cortical gyration abnormalities. The most predictive variables in the logistic regression model were cortical gyration abnormalities, coloboma, and sex. Conclusion The iuMRI findings may suggest prenatal diagnosis of AIC syndrome with significant impact on parental counseling. Among possible differential diagnoses, tubulinopathies emerged.

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Epidemiology of Pathological Online Games Use and Its Effect on Anxiety and Insomnia in Chinese Ethnic Minorities Adolescents

10.21203/rs.3.rs-1155921/v1 ◽

2021 ◽

Author(s):

Qiaoyue Wei ◽

Shengjie Zhang ◽

Yuli Pan ◽

Hong Hu ◽

Fenglan Chen ◽

...

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Logistic Regression Analysis ◽

Short Form ◽

Binary Logistic Regression ◽

Online Games ◽

Binary Logistic Regression Analysis ◽

Special Focus ◽

Chi Square ◽

Chi Square Analysis

Abstract Background: The growing popularity and frequency of online games use has resulted in a large number of studies reporting various mental problems associated with its abuse in adolescents. In this article, we examined the prevalence of pathological online games use (POGU) and explored the associations of the POGU with anxiety and insomnia symptoms with minority youth in China.Methods: 1494 students completed a questionnaire of Problematic Online Gaming Questionnaire Short-Form (POGQ-SF), Generalized Anxiety Condition iems (GAD-7), and the Athens Insomnia Scale (AIS). Chi-square and binary logistic regression analysis were used to explore the association between pathological online games and anxiety/insomnia. Results: 356 (23.83%) respondents reported they had pathological online games use. Chi-square analysis shows that gender, grade, marital status of parents and exercise situation were significantly associated with POGU. Binary logistic regression analysis showed that those who had POGU were at significantly higher risk for anxiety and insomnia, compared to those who without POGU.Conclusion: We found a high incidence of POGU and a positive association among anxiety, insomnia and POGU. Thus, special focus should be paid to those who have suffered POGU. And, it is worth addressing the adverse effects of POGU on anxiety and insomnia.

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Determinants of abortion among youth 15–24 in Ethiopia: A multilevel analysis based on EDHS 2016

PLoS ONE ◽

10.1371/journal.pone.0248228 ◽

2021 ◽

Vol 16 (3) ◽

pp. e0248228

Author(s):

Girma Gilano ◽

Samuel Hailegebreal

Keyword(s):

Logistic Regression ◽

Economic Status ◽

Binary Logistic Regression ◽

P Value ◽

Binary Logistic Regression Analysis ◽

Individual Level ◽

Access Problem ◽

Younger Age ◽

Youth Population ◽

Policy Direction

Introduction Determinants of the magnitude of abortion among women of diverse social and economic status, particularly in Africa poorly understood because of the missing information in most countries. In this study, we addressed abortion and its determinants among youth women of 15–24 ages to provide clear direction for policymaking in Ethiopia. Methods We examined the 2016 Ethiopian demographic health survey data downloaded from the EDHS website after obtaining permission on abortion among 15–24 age women. We applied bivariate and multilevel binary logistic regression. Community and Individual level abortion predictors passed through a three-level binary logistic regression analysis where we used p-value <0.05 and adjusted odds ratios (AOR) with 95% confidence intervals (CI). Result The abortion among the youth population in this study was 2.5%. Factors associated with pregnancy were age group 20–24 2.5(1.6–3.8), youth with one birth 0.65(0.44–0.96), youth with 2–5 births 0.31(0.18–0.55), age ≥18 0.50(0.33–0.76), married 38(17–84), divorced 20(7–55), birth in the last five years 0.65(0.44–0.96), middle wealth youth 1.7(1.0.4–2.8), being in Amhara0.31(0.11–0.85), and 0.30(0.12–0.77). Conclusion Less abortion occurred in economically poor youths. It is a noble finding; however, the access problem might lead to the result. We observed more abortions in age <18years; those have not given birth until the data collection date. It portrays forth clear policy direction for politicians and all other stakeholders to intervene in the problem. The analysis also showed abortion increased with age. It shows that as age increased, youths disclose abortion which is rare at an early age, and again given an essential clue for the next interventions. The fact in this study is both age and marriage affected abortion similarly. It might be because of various culture-related perceptions where it is not appropriate for an unmarried woman to appear with any pregnancy outcome as the reason behind the decreased number of abortions at a younger age. Thus, more attention is required during implementation for unmarried and lower age youth regardless of the magnitude of the abortion.

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Predicting Burn Mortality Using a Simple Novel Prediction Model

Indian Journal of Plastic Surgery ◽

10.1055/s-0040-1721867 ◽

2021 ◽

Author(s):

Sneha Sharma ◽

Raman Tandon

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Prediction Model ◽

Receiver Operating Characteristic ◽

Logistic Regression Analysis ◽

Operating Characteristic ◽

Binary Logistic Regression ◽

Apache Ii ◽

Apache Ii Score ◽

Binary Logistic Regression Analysis

Abstract Background Prediction of outcome for burn patients allows appropriate allocation of resources and prognostication. There is a paucity of simple to use burn-specific mortality prediction models which consider both endogenous and exogenous factors. Our objective was to create such a model. Methods A prospective observational study was performed on consecutive eligible consenting burns patients. Demographic data, total burn surface area (TBSA), results of complete blood count, kidney function test, and arterial blood gas analysis were collected. The quantitative variables were compared using the unpaired student t-test/nonparametric Mann Whitney U-test. Qualitative variables were compared using the ⊠2-test/Fischer exact test. Binary logistic regression analysis was done and a logit score was derived and simplified. The discrimination of these models was tested using the receiver operating characteristic curve; calibration was checked using the Hosmer—Lemeshow goodness of fit statistic, and the probability of death calculated. Validation was done using the bootstrapping technique in 5,000 samples. A p-value of <0.05 was considered significant. Results On univariate analysis TBSA (p <0.001) and Acute Physiology and Chronic Health Evaluation II (APACHE II) score (p = 0.004) were found to be independent predictors of mortality. TBSA (odds ratio [OR] 1.094, 95% confidence interval [CI] 1.037–1.155, p = 0.001) and APACHE II (OR 1.166, 95% CI 1.034–1.313, p = 0.012) retained significance on binary logistic regression analysis. The prediction model devised performed well (area under the receiver operating characteristic 0.778, 95% CI 0.681–0.875). Conclusion The prediction of mortality can be done accurately at the bedside using TBSA and APACHE II score.

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MO376CLINICAL OUTCOMES OF ACUTE KIDNEY INJURY FOLLOWING SNAKE BITE INJURIES

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfab082.0030 ◽

2021 ◽

Vol 36 (Supplement_1) ◽

Author(s):

Weerakit Naweera ◽

Thapat Wannarong

Keyword(s):

Acute Kidney Injury ◽

Logistic Regression ◽

Kidney Injury ◽

Binary Logistic Regression ◽

Cross Sectional Study ◽

Renal Recovery ◽

Binary Logistic Regression Analysis ◽

Cross Sectional ◽

Hospital Arrival ◽

Russell’S Viper

Abstract Background and Aims Snakebite is a common animal bite injury in tropical countries. Acute kidney injury (AKI) is an important complication in snakebite patients. This study aimed to comprehensively investigate the clinical profiles and outcomes of patients following hematotoxin-related snakebite associated with kidney impairment. Method We conducted a hospital-based, cross-sectional study of 238 patients with hematotoxin-related snakebite injuries. Data were retrieved from the King Narai Hospital Registry from October 2014 to August 2020. The prevalence of complications associated with snakebite injuries, including acute kidney injury (AKI) and its severity, was determined. Univariate and Multivariate predictors of AKI diagnosis were evaluated using binary logistic regression analysis Results A total of 238 patients, with 63.4% men, median (IQR) age 49.8 (39-61) years and median duration from injury to a hospital arrival of 1 hour (0.5-2) hours, were injured by Green pit viper (85.7%), Russell’s viper (12.6%) and Malayan pit viper (1.7%). AKI mostly occurred in Russell’s viper group 66.7%. An AKI was reported in thirty (12.6%, 95% CI: 8.7 % - 17.5%) patients, with the severity of 66.7% stage one, 6.7% stage two, 26.6% stage three by KDIGO classifications, and 13.3% requiring hemodialysis. Complete renal recovery was seen in twenty-two patients (73.3%), while partial renal recovery was 23.3%. Other complications included 84.4 % limb cellulitis, 4.6% significantly bleeding, 2.5% hypotension, 25.6% prolonged venous clotting time (VCT), 46.7% prolonged prothrombin time (PT), and 14.3% prolonged partial thromboplastin time (PTT). Of total patients, 60.1% were treated with anti-venom. Mortality was relatively low (0.4%). In multivariable logistic regression analyses, AKI was significantly associated with time to hospital arrival more than 3 hours (p = 0.04), Russell’s viper bitten (p = 0.01), clinical bleeding (p = 0.01), and prolonged PT (p < 0.01). Conclusion The prevalence of AKI in patients bitten by hematotoxin snakes was 12.6%, mostly from Russell’s viper. Factors associated with AKI outcomes were time to hospital arrival more than 3 hours, Russell’s viper bitten, clinical bleeding, and prolonged PT. Besides, one-fourth of AKI patients turned to chronic kidney disease.

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Abstract 3734: Presurgical fMRI and Morbidity Outcomes in Patients with Vascular Lesions

Stroke ◽

10.1161/str.43.suppl_1.a3734 ◽

2012 ◽

Vol 43 (suppl_1) ◽

Author(s):

Andrew C Radtke ◽

Joshua Pankratz ◽

Ryan Holdsworth ◽

Dovile Baniulis ◽

Nicole Kornder ◽

...

Keyword(s):

Logistic Regression ◽

Preoperative Planning ◽

Binary Logistic Regression ◽

Vascular Lesion ◽

Vascular Lesions ◽

Motor Deficits ◽

Binary Logistic Regression Analysis ◽

Language Mapping ◽

Motor Mapping ◽

The Relationship

Background fMRI is being increasingly used as an adjunct imaging technique for preoperative planning for patients with various brain lesions. The proximity of the lesion to eloquent cortex is a major factor in guiding surgical planning. Our group has previously reported significant association between the distance between brain tumor periphery and area of fMRI activation (Lesion-Activation Distance; LAD) and morbidity and mortality outcomes. This study investigated the relationship between vascular lesion LAD and morbidity. Methods This study was a retrospective analysis of data from patients with vascular lesions [arteriovenous malformations (AVMs) (n=49), and cavernomas (n=57)], who had received fMRI as part of their preoperative planning. The preoperative fMRI included motor mapping (n=87) and/or language mapping (n=102). The fMRI paradigms were chosen based on observed preoperative weakness (aphasia, paresis) and anticipated functional areas of the brain that may be affected by treatment. Results Multiple logistic regression analyses showed that a model that combines Age and Language LAD was a significant predictor of postoperative deficits (p= 0.04). Broca’s LAD(1-2 cm) X Age was a significant predictor of postoperative deficits (change in odds ratio (OR) =0.82, CI:0.68-0.98). The relationship between Brocas’s LAD and postoperative aphasia and Broca’s LAD and pre and postoperative aphasia trended towards significance (p = .08 and p =.07 respectively). Wernicke’s LAD, independently or combined with Age, was not a significant predictor of postoperative deficits. Binary logistic regression analysis for SMC LAD and postop deficits did not reach significance (p =.10). There were no significant differences in postoperative language or motor deficits as a function of gender or handedness. Conclusions These results suggest that both age and the proximity of a vascular lesion to language LAD are factors that can help predict postoperative outcomes, especially for Broca’s LAD. The lack of similar results when investigating the relationship between Wernicke’s LAD and postoperative deficits suggests potential brain reorganization and/or robustness of this brain region. These results have implications for the potential use of fMRI as a presurgical tool for language mapping in patients with vascular lesions.

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Predictive Value of Technical Throwing Skills on Nomination Status in Youth and Long-Term Career Attainment in Handball

Sports Medicine - Open ◽

10.1186/s40798-021-00397-5 ◽

2022 ◽

Vol 8 (1) ◽

Author(s):

Till Koopmann ◽

Franziska Lath ◽

Dirk Büsch ◽

Jörg Schorer

Keyword(s):

Logistic Regression ◽

National Level ◽

Age Groups ◽

Age Group ◽

Regression Analyses ◽

Chi Square ◽

Career Attainment ◽

Future Performance ◽

Younger Age

Abstract Background Research on talent in sports aims to identify predictors of future performance. This study retrospectively investigated 1) relationships between young handball field players’ technical throwing skills and (a) their potential nomination to youth national teams and (b) their long-term career attainment 10 years later, and 2) associations between nomination status and career attainment. Results Results from retrospectively predicting nomination status and career attainment using logistic regression analyses show that technical throwing skills were partly able to explain players’ nomination status (Nagelkerke R2: females 9.2%, males 13.1%) and career attainment (Nagelkerke R2: 9.8% for female players). Here, variables throwing velocity and time on exercise showed statistically significant effects. In addition, nomination status and career attainment were shown to be associated using chi-square tests (w of .37 and .23 for female and male players, respectively) and nomination status as a predictor increased the prediction of career attainment remarkably (Nagelkerke R2: females 20.3%, males 12.7%). Conclusions Given these results, basic technical throwing skills may serve rather as a prerequisite in this age group on national level, emphasizing its importance already on lower levels and in younger age groups. Furthermore, advantages from entering the national TID system early especially for females are discussed.

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Predicting organizational performance from motivation in Oromia Seed Enterprise Bale branch

Humanities and Social Sciences Communications ◽

10.1057/s41599-021-00742-9 ◽

2021 ◽

Vol 8 (1) ◽

Author(s):

Askalech Feyisa Jobira ◽

Abdulnasir Abdulmelike Mohammed

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Intrinsic Motivation ◽

Organizational Performance ◽

Logistic Regression Analysis ◽

Extrinsic Motivation ◽

Binary Logistic Regression ◽

Moderate Level ◽

Binary Logistic Regression Analysis ◽

Study Results

AbstractMotivation is one of the most researched yet crucial topics in academia from various perspectives. Despite this, researches show mixed results about the effect of extrinsic motivation on intrinsic motivation and organizational performance. Studies in Ethiopia also lack causal analysis and theoretical underpinning that made contributions from academia very little. Hence, this research is important to assess the effect of extrinsic motivation on intrinsic motivation and organizational performance from a cognitive evaluation theory perspective. The researchers adopted an explanatory research design with a quantitative approach. The entire 119 employees of the Oromia Seed Enterprise, Bale branch were included in the study to collect primary data through a close-ended questionnaire. The collected data was processed by SPSS software version 20. The relationship analysis was addressed by correlation and binary logistic regression analysis. Seen from extrinsic and intrinsic motivation aspects, the findings of the study showed that Oromia Seed Enterprise had a moderate level of organizational performance and a moderate level of employees’ motivation. The correlation analysis result indicated that employees’ extrinsic and intrinsic motivation had a positive relationship with organizational performance. The binary logistic regression analysis also indicated that extrinsic and intrinsic motivation had a positive and significant influence on organizational performance. However, the interaction effect of intrinsic and extrinsic motivation on organizational performance was not significant, implying the absence of influence when both intrinsic and extrinsic motivations happen at the same time. Finally, the study results have a theoretical contribution for compensating the lack of actual experience in the Ethiopian organization’s context. Equally, the understanding of the moderated relationship among the study variables may encourage Oromia Seed Enterprise and its managers to develop a practical motivation system, which entertains the complex interaction of motivation variables to improve organizational performance. In addition, studies of this nature can inform policymakers to strengthen an incentive system as well as other motivation veins in the Ethiopian public organizations.

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