Acute Renal Failure Secondary to an Unusual Familial Metabolic Myopathy

Nephron ◽  
2021 ◽  
pp. 1-6
Author(s):  
Carolt Arana ◽  
Jacqueline Del Carpio ◽  
Leonor Fayos ◽  
Elisabet Ars ◽  
Nadia Ayasreh ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Genetic Testing ◽  
Kidney Failure ◽  
Soft Tissues ◽  
Crush Syndrome ◽  
Acute Kidney Failure ◽  
Metabolic Myopathy ◽  
History Of ◽  
Diffuse Uptake

Rhabdomyolysis is a major cause of acute kidney failure. The etiology is diverse, from full-blown crush syndrome to less frequent causes, such as metabolic myopathy. We describe the case of a 35-year-old male with a history of intermittent myalgias who was admitted to hospital with acute renal failure secondary to rhabdomyolysis. Moderate to intense diffuse uptake of technetium-99m was seen in soft tissues at scintigraphy. The diagnosis of metabolic myopathy was confirmed after careful workup and genetic testing.

scholarly journals Treating Severe Hyperkalemia with Renal Replacement Therapy in Acute Kidney Failure Due To Rhabdomyolysis

2014 ◽  
Vol 2 (2) ◽  
pp. 313-315
Author(s):  
Alfred Ibrahimi ◽  
Saimir Kuci ◽  
Ervin Bejko ◽  
Stavri Llazo ◽  
Esmerilda Bulku ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Kidney Failure ◽  
High Volume ◽  
Acute Kidney Failure ◽  
Cell Destruction ◽  
Severe Hyperkalemia ◽  
Massive Cell

Rhabdomyolysis and myoglobinuria are the main cause of the acute renal failure. Hyperkalemia is life threating complication of rhabdomyolisis due to massive cell destruction. We report a case of very severe hyperkalemia treated successfully with high volume hemodiafiltration (CVVHDF).

scholarly journals Bartonella-Associated Endocarditis with Severe Active Crescentic Glomerulonephritis and Acute Renal Failure

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Ramanath Dukkipati ◽  
Benjamin Lawson ◽  
Cynthia C. Nast ◽  
Anuja Shah
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Aortic Valve ◽  
Immune Complex ◽  
Kidney Failure ◽  
Crescentic Glomerulonephritis ◽  
Kidney Biopsy ◽  
Acute Kidney Failure ◽  
Complex Deposition ◽  
Culture Negative

We report a case of severe acute kidney failure due to crescentic glomerulonephritis who presented initially with culture-negative endocarditis with vegetations on the aortic valve. Anti-nuclear and anti-phospholipid antibodies were positive with initially negative anti-neutrophil cytoplasmic antibodies (ANCAs). Kidney biopsy revealed severe acute crescentic glomerulonephritis with mesangial immune complex deposition. PR3-ANCA subsequently become positive, and the patient developed worsening kidney failure requiring hemodialysis. This case illustrates that Bartonella can present as culture-negative endocarditis with severe crescentic glomerulonephritis with positive PR-3 ANCAs and can mimic ANCA-associated crescentic glomerulonephritis.

scholarly journals Acute Renal Failure after Consumption of Fish Gall Bladder

2014 ◽  
Vol 2014 ◽  
pp. 1-2 ◽  
Author(s):  
Nishant Raj Pandey ◽  
Bian Yu Yao ◽  
Sudha Khakurel
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Conservative Treatment ◽  
Gall Bladder ◽  
Organ Dysfunction ◽  
Multiple Organ Dysfunction Syndrome ◽  
Kidney Failure ◽  
Multiple Organ ◽  
Acute Kidney Failure ◽  
Multiple Organ Dysfunction

A case of acute renal failure after consumption of fish gall bladder as traditional medical remedy is reported. The patient fully recovered with conservative treatment. The risk of acute kidney failure and even multiple organ dysfunction syndrome following ingestion of fish gall bladder is highlighted.

scholarly journals Expanding the pool of kidney donors: use of kidneys with acute renal dysfunction

2015 ◽  
Vol 13 (2) ◽  
pp. 319-325 ◽  
Author(s):  
Ana Cristina Carvalho de Matos ◽  
Lúcio Roberto Requião-Moura ◽  
Gabriela Clarizia ◽  
Marcelino de Souza Durão Junior ◽  
Eduardo José Tonato ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Renal Dysfunction ◽  
Patient Survival ◽  
Machine Perfusion ◽  
Acute Renal Dysfunction ◽  
Morphological Findings ◽  
History Of ◽  
Expanded Criteria ◽  
Support Decision Making

ABSTRACT Given the shortage of organs transplantation, some strategies have been adopted by the transplant community to increase the supply of organs. One strategy is the use of expanded criteria for donors, that is, donors aged >60 years or 50 and 59 years, and meeting two or more of the following criteria: history of hypertension, terminal serum creatinine >1.5mg/dL, and stroke as the donor´s cause of death. In this review, emphasis was placed on the use of donors with acute renal failure, a condition considered by many as a contraindication for organ acceptance and therefore one of the main causes for kidney discard. Since these are well-selected donors and with no chronic diseases, such as hypertension, renal disease, or diabetes, many studies showed that the use of donors with acute renal failure should be encouraged, because, in general, acute renal dysfunction is reversible. Although most studies demonstrated these grafts have more delayed function, the results of graft and patient survival after transplant are very similar to those with the use of standard donors. Clinical and morphological findings of donors, the use of machine perfusion, and analysis of its parameters, especially intrarenal resistance, are important tools to support decision-making when considering the supply of organs with renal dysfunction.

scholarly journals Ascites, a New Cause for Bilateral Hydronephrosis: Case Report

2009 ◽  
Vol 9 ◽  
pp. 1035-1039 ◽  
Author(s):  
Deepika Jain ◽  
Smrita Dorairajan ◽  
Madhukar Misra
Keyword(s):  
Renal Failure ◽  
Renal Function ◽  
Acute Renal Failure ◽  
Liver Cirrhosis ◽  
Case Report ◽  
Abdominal Ultrasound ◽  
Back Pressure ◽  
Alcoholic Liver Cirrhosis ◽  
Bilateral Hydronephrosis ◽  
History Of

Bilateral hydronephrosis secondary to urinary obstruction leads to a buildup of back pressure in the urinary tract and may lead to impairment of renal function. We present a case of a 57-year-old male with a history of alcoholic liver cirrhosis, who presented with tense ascites and acute renal failure. Bilateral hydronephrosis was seen on abdominal ultrasound. Multiple large-volume paracenteses resulted in resolution of hydronephrosis and prompt improvement in renal function.

scholarly journals Acute renal failure related to the crush syndrome: towards an era of seismo‐nephrology?

2000 ◽  
Vol 15 (10) ◽  
pp. 1517-1521 ◽  
Author(s):  
Raymond Vanholder ◽  
Mehmet S. Sever ◽  
Ekrem Erek ◽  
Norbert Lameire
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Crush Syndrome

Risk of acute renal failure among breast cancer patients and chemotherapy treatment of breast cancer patients with a history of renal insufficiency in a commercially-insured population in the United States

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e22104-e22104 ◽  
Author(s):  
W. J. Langeberg ◽  
C. D. O'Malley ◽  
C. W. Critchlow ◽  
J. P. Fryzek
Keyword(s):  
Breast Cancer ◽  
Renal Failure ◽  
Acute Renal Failure ◽  
Renal Insufficiency ◽  
Cancer Patients ◽  
Cancer Diagnosis ◽  
The United States ◽  
First Year ◽  
Breast Cancer Patients ◽  
History Of

e22104 Background: Risk of acute renal failure (ARF) among breast cancer (BC) patients may increase with nephrotoxic chemotherapy and other exposures, but this risk is not well characterized. Furthermore, among patients who present with renal insufficiencies (RI) at cancer diagnosis, subsequent treatment patterns are not well described. Methods: We performed a retrospective cohort study using a large national commercial claims database. The cohort included all women diagnosed with BC from 2000 to 2007 who were 18–64 years at diagnosis with no history of cancer (n=13,296). We defined a diagnosis of BC as at least one inpatient or two outpatient claims more than 30 days apart with an ICD-9 code of 174. Among patients with no history of RI (n=13,150), we calculated the cumulative incidence (CI) of ARF_the proportion with at least one inpatient or two outpatient claims with an ICD-9 code of 584 or 586 in the first year following cancer diagnosis. Treatment for BC patients with a history of RI (n=146) was also assessed. Results: Among BC patients with no history of RI, 0.3% were diagnosed with ARF within a year after cancer diagnosis. The CI of ARF was higher in patients with metastases: 0.7% for any metastasis, 2.3% for bone metastasis, and 0.1% for no metastasis. The CI of ARF among patients undergoing radiation or mastectomy was similar to the overall rate (0.3%) but was higher in patients receiving nephrotoxic chemotherapy (1.0%) or intravenous bisphosphonates (IV BPs) (2.1%). The CI of ARF was higher in patients with congestive heart failure (1.4%), diabetes (0.9%), and/or hypertension (0.8%) at cancer diagnosis compared to patients without these comorbidities (0.2%). Among BC patients with a history of RI, 7.5% were administered nephrotoxic chemotherapy, 30.1% received potentially nephrotoxic chemotherapy, and 1.4% were given IV BPs. Conclusions: Breast cancer patients who present with comorbidities, develop metastases, or are given nephrotoxic chemotherapy or IV bisphosphonates are at higher risk of acute renal failure in the first year after breast cancer diagnosis. More research is warranted on the treatment of breast cancer patients with a history of renal insufficiency. [Table: see text]

scholarly journals Bright's Disease, Malaria, and Machine Politics: The Story of the Illness of President Chester A. Arthur

2017 ◽  
Vol 03 (04) ◽  
pp. e181-e187
Author(s):  
Theodore Pappas
Keyword(s):  
Renal Failure ◽  
Differential Diagnosis ◽  
Medical History ◽  
Kidney Failure ◽  
Train Station ◽  
History Of ◽  
Machine Politics

AbstractIn July of 1881, President James A. Garfield was shot in the back at the Sixth Street Train Station in Washington, D.C. Garfield died after an extended illness and Chester A. Arthur assumed the presidency on September 20, 1881. He served the remaining three and a half years but was ill for most of his term. Arthur died of the complications of Bright's disease less than two years after leaving office. In the 1880s, Bright's disease was the syndrome that described renal failure associated with proteinuria, but the etiology of Arthur's kidney failure has never been determined. Arthur is one of our least understood Presidents, owing to his brief tenure in office, his death shortly after leaving office, and the fact that he burned all his personal papers just prior to his death. This manuscript will explore the medical history of Chester A. Arthur, including his presumed diagnosis of malaria, his symptoms during his declining health, and will define the differential diagnosis of the causes of his renal failure that culminated in his death in November of 1886.

scholarly journals A Rare Case of Acute Renal Failure Secondary to Rhabdomyolysis Probably Induced by Donepezil

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Osman Zikrullah Sahin ◽  
Teslime Ayaz ◽  
Suleyman Yuce ◽  
Fatih Sumer ◽  
Serap Baydur Sahin
Keyword(s):  
Emergency Department ◽  
Renal Failure ◽  
Creatine Kinase ◽  
Acute Renal Failure ◽  
Rare Case ◽  
Laboratory Studies ◽  
Case Presentation ◽  
History Of ◽  
One Year ◽  
Renal Function Tests

Introduction. Acute renal failure (ARF) develops in 33% of the patients with rhabdomyolysis. The main etiologic factors are alcoholism, trauma, exercise overexertion, and drugs. In this report we present a rare case of ARF secondary to probably donepezil-induced rhabdomyolysis.Case Presentation. An 84-year-old male patient was admitted to the emergency department with a complaint of generalized weakness and reduced consciousness for two days. He had a history of Alzheimer’s disease for one year and he had taken donepezil 5 mg daily for two months. The patient’s physical examination revealed apathy, loss of cooperation, and decreased muscle strength. Laboratory studies revealed the following: urea: 128 mg/dL; Creatinine 6.06 mg/dL; creatine kinase: 3613 mg/dL. Donepezil was discontinued and the patient’s renal function tests improved gradually.Conclusion. Rhabdomyolysis-induced acute renal failure may develop secondary to donepezil therapy.

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