scholarly journals Вплив поліморфізму генів PTHR1 та COL1A1 на розвиток захворювань тканин пародонта у людей молодого віку

2017 ◽  
Author(s):  
M. A. Luchynskyi ◽  
Y. V. Boliuk ◽  
V. M. Luchynskyi
Keyword(s):  
Young People ◽  
Periodontal Diseases ◽  
Main Group ◽  
Control Group ◽  
Type I ◽  
Periodontal Tissue ◽  
Endogenous Factors ◽  
Stage Of Development ◽  
The Difference ◽  
Collagen Chain

At the present stage of development of dentistry, the leading Ukrainian and foreign scientists devote a considerable part of the research to a deeper study of the etiology and pathogenetic mechanisms of periodontal tissue diseases and the influence of various exogenous and endogenous factors on their course.The aim of the study – to learn the ability and methods of forecasting and early diagnosis of the periodontal tissue lesions in young people. Materials and Methods. During our research we examined 24 young people with periodontal tissue diseases, who were included to the main group, and 15 healthy people, who formed the control group. The complex clinical examination was performed in each research group. It was studied the distribution of polymorphous variants of the type I parathormone receptor and the α1-chain of collagen gene with a help of polymerase chain reaction by restrictase cleavage of DNA fragments and electrophoresis in polyacrylamide gel (AA/BA 29:1). Results and Discussion. The distribution of genotypes by PTHR1 gene in control group was similar to those in main group (p>0.05). Also we didn’t find the difference between frequencies of the separate alleles in people with periodontal tissue pathology and without it (p>0.05). Yes, the repetitions of the allele 5 encoding normal type I parathormone receptor were found more often, comparing with the allele 6 that is responsible for the formation of unfunctional PTHR1 (р<0.001) in both main and control groups. The dominance of the genotype TT, which corresponds to the pathology, was found in young people with the periodontal tissue lesions – (38.46 ± 4.79) %, while among the control group the genotype of norm GG was met the most often – (68.24±5.08) %. Also, the frequency of repetitions of the allele T encoding the imperfect collagen chain was (57.60±3.79) % in young people with periodontal diseases, and in the control group this figure was (13.27±2.81) %, p<0.001.  Conclusions. According to our results the presence of allele T and genotype TT that correspond the imperfect collagen chain may be one of the causes of periodontal tissue pathology.

scholarly journals EVALUATION OF THE EFFECTIVENESS OF PREVENTION AND TREATMENT OF CHRONIC CATARRHAL GINGIVITIS IN CHILDREN WITH OLIGOPHRENIA

2019 ◽  
Vol 19 (4) ◽  
pp. 49-53
Author(s):  
Н. Dutko
Keyword(s):  
Periodontal Diseases ◽  
Main Group ◽  
Control Group ◽  
Periodontal Tissue ◽  
Effective Measure ◽  
Standard Methods ◽  
Treatment And Prevention ◽  
Prophylactic Measures ◽  
Dental Diseases

Prevention of hard dental tissue diseases and periodontal diseases in children is one of the urgent issues of pediatric dentistry. This is especially true for the category of children with psychoneurological pathology. Due to the high prevalence of dental diseases, decreased immunity, and sometimes difficult assess to dental care for children with mental retardation, dental disease prevention is the most effective measure to maintain the normal functioning of the dentofacial apparatus. The results obtained by examining the children with oligophrenia allowed us to work up an algorithm for therapeutic and preventive measures aimed at preventing the development of oral tissue diseases in these children. The algorithm included measures for primary and secondary prevention of periodontal diseases. To assess the efficacy of the algorithm, the study involved a group of 55 mentally impaired children. The control group consisted of 50 children with oligophrenia, who were treated by traditional methods. Taking into account the burdened mental status of the children when developing the individual hygiene regimens, a motivational approach was worked out in co-operation with a psychiatrist and a paediatrician. Evaluation of treatment outcomes in the groups was performed in 1 month after the completion of the full course of treatment and prevention and in long-term intervals, in 6 and 12 months. Clinical evaluation of treatment efficacy was performed according to the following criteria: "normalization", "improvement", "progression". In one month following the regimen proposed, the "normalization" of the affected tissues was diagnosed in 40 children of the main group (72,73 ± 6,06%), p <0,01. The "improvement" of periodontal tissue condition was observed in 10 children (18.18 ± 5.25%), p <0.05. Only 5 children in the main group (9.09 ± 3.91%) failed to demonstrate any positive changes. In 6 months following the application of the treatment and prevention algorithm, the children of the main group demonstrate the "normalization" of periodontal tissue in 65,45 ± 6,47% of cases, while in the children of the control group this indicator was twice lower, 32,00 ± 6.66%, p <0.01. The "improvements" were found in 21.82 ± 5.62% of the children in the main group and in 14.00 ± 4.96% of the children in the control group, p <0.05. No effect of treatment and progression of inflammatory process were observed in 7 children of the main group that was in 4.2 times less than in children of the control group. In long-term follow-up, in 1 year, 61.82 ± 6.61% of children with oligophrenia, who received the treatment and prophylactic measures proposed demonstrated the "normalization" of the periodontal tissue health. In the children treated with standard methods, this indicator was 2.2 times lower (28.00 ± 6.41%), p <0.01. The "improvement" of periodontal condition was recorded in 27.27 ± 6.06% of children in the main group versus 10.00 ± 4.28% of the children in the control group, p <0.01. Treatment for 10.91 ± 4.24% of the children of the main group failed to be effective, but for the children of the control group this indicator was in 5.7 times higher during the long-term observation. The data obtained indicate the lack of effectiveness of standard methods of treatment for chronic catarrhal gingivitis and confirm the high efficiency of the developed algorithm for treatment and prevention of dental diseases in children with oligophrenia. The authors of this article confirm that the research and publication of the results were not associated with any conflicts regarding commercial or financial relations, relations with organizations and/or individuals who may have been related to the study, and interrelations of co-authors of the article.

scholarly journals The effectiveness of the use of anti-dysbiotic hepatoprotector in the complex treatment of patients with periodontal inflammatory diseases on the background of chronic non-calculous cholecystitis

2018 ◽  
Author(s):  
A. I. Furdychko ◽  
A. Yu. Buchkovska ◽  
M. A. Pasichnyk
Keyword(s):  
Periodontal Disease ◽  
Comparison Group ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Main Group ◽  
Control Group ◽  
Complex Treatment ◽  
Hepatobiliary System ◽  
The Difference ◽  
Calculous Cholecystitis

Summary. Inflammatory periodontal diseases continue to be one of the pressing problems of modern dentistry [1]. It is known that there is a close relationship between general-somatic pathology and diseases of the oral cavity [2]. The aim of the study – to learn the effectiveness of the use of anti-dysbiotic hepatoprotector in the complex treatment of patients with periodontal inflammatory diseases on the background of chronic non-calculous cholecystitis. Materials and Methods. The main (group 1) group consisted of 106 people who suffered from inflammatory periodontal disease (IPD) with concomitant chronic non-calculous cholecystitis (CNC). The comparison group included 92 patients with IPD without concomitant pathology (group 2). To compare the research results of the patients with IPD, 30 healthy teethed individuals without periodontal pathology and without somatic diseases (group 3 or the control group) were involved. The state of the hepatobiliary system in patients of the main group was assessed by the doctors of the Gastroenterology Department of Zolochiv District Hospital of Lviv region. Results and Discussion. The symptomatic HCG and the presence of solid and soft dental deposits were diagnosed in all patients. The Green-Vermillion’s index was the highest in patients from the main group (1.67±0.01); it was probably (p <0.05) higher than that in the comparison group (1.54±0.04), as well as in the control group (0.44±0.07). The PMA index in the subgroup 1A immediately after treatment decreased by 9.7 (p <0.001) times. The index of bleeding in the subgroup 1A decreased by 10.7 (p <0.001) times. The PMA index in the subgroup 1A immediately after treatment decreased by 10.4 (p <0.001) times. The index of bleeding in the subgroup 1A under the influence of the proposed therapy decreased by 6.5 (p <0.001) times.The difference regarding the data before treatment remained lower by 2.2 times and 2.0 (p <0.001) times, however, the difference between the subgroups 1A and 1B in 3 months and 6 months was already 2.1 times in both cases. Conclusions. It was found that the clinical course of inflammatory periodontal diseases was much more difficult in these patients. The presence of pathology in the hepatobiliary system in patients increases the risk of periodontal disease. Therefore, in order to improve the efficacy of treatment, it is advisable to use this antidysbiotic drug in the complex treatment, and the results obtained in 3 and 6 months after treatment indicate a long-lasting positive effect.

scholarly journals Autophagy facilitates type I collagen synthesis in periodontal ligament cells

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tomomi Nakamura ◽  
Motozo Yamashita ◽  
Kuniko Ikegami ◽  
Mio Suzuki ◽  
Manabu Yanagita ◽  
...  
Keyword(s):  
Periodontal Ligament ◽  
Collagen Synthesis ◽  
Type I Collagen ◽  
Periodontal Diseases ◽  
Polyacrylamide Gel Electrophoresis ◽  
Sodium Dodecyl ◽  
Physiological Role ◽  
Type I ◽  
Periodontal Tissue ◽  
Pdl Cells

AbstractAutophagy is a lysosomal protein degradation system in which the cell self-digests its intracellular protein components and organelles. Defects in autophagy contribute to the pathogenesis of age-related chronic diseases, such as myocardial infarction and rheumatoid arthritis, through defects in the extracellular matrix (ECM). However, little is known about autophagy in periodontal diseases characterised by the breakdown of periodontal tissue. Tooth-supportive periodontal ligament (PDL) tissue contains PDL cells that produce various ECM proteins such as collagen to maintain homeostasis in periodontal tissue. In this study, we aimed to clarify the physiological role of autophagy in periodontal tissue. We found that autophagy regulated type I collagen synthesis by elimination of misfolded proteins in human PDL (HPDL) cells. Inhibition of autophagy by E-64d and pepstatin A (PSA) or siATG5 treatment suppressed collagen production in HPDL cells at mRNA and protein levels. Immunoelectron microscopy revealed collagen fragments in autolysosomes. Accumulation of misfolded collagen in HPDL cells was confirmed by sodium dodecyl sulfate–polyacrylamide gel electrophoresis. E-64d and PSA treatment suppressed and rapamycin treatment accelerated the hard tissue-forming ability of HPDL cells. Our findings suggest that autophagy is a crucial regulatory process that facilitates type I collagen synthesis and partly regulates osteoblastic differentiation of PDL cells.

scholarly journals Clinical and cytological characteristic of a condition of the oral cavity at pregnant women with various types of a diabetes mellitus

2016 ◽  
Vol 65 (6) ◽  
pp. 45-51 ◽  
Author(s):  
Ludmila Yu Orekhova ◽  
Anna A Aleksandrova ◽  
Ludmila A Aleksandrova ◽  
Ramila S Musaeva ◽  
Gulrukhsor Kh Tolibova ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Oral Cavity ◽  
Pregnant Women ◽  
Inflammatory Diseases ◽  
Type I Diabetes ◽  
Periodontal Diseases ◽  
Diabetes Mellitus Type 1 ◽  
Control Group ◽  
Type I ◽  
Liquid Based Cytology

Introduction. More and more researches dedicated to the communication of diseases of the oral cavity of pregnant women with diabetes. It is proved that the intensity of caries and inflammatory periodontal diseases (gingivitis and periodontitis) increase significantly during pregnancy, while the presence of comorbidities, such as diabetes, increase these indexes.Aim. The aim of the work was to study the dental status of pregnant women with diabetes.Materials and methods. The study compared women with gestational diabetes mellitus, type 1 diabetes, and type 2 diabetes, to a control group of pregnant women without diabetes. In addition to clinical research methods, liquid-based cytology of the contents of the gingival sulcus was performed.Results. The results of clinical and laboratory studies have shown that inflammatory diseases of periodontium and teeth within pregnant women with diabetes are more common than within the pregnant women without this disease. It should be noted that the frequency of occurrence and severity of these diseases in the pregnant women with type I diabetes is higher than in the other groups.Conclusion. Pregnant women with diabetes are at risk for dental disease and require more attention from dentists, endocrinologists and obstetricians. The use of liquid-based cytology method helps in the diagnosis of inflammatory periodontal diseases.

scholarly journals Features of the dental status of the Nogais who lived on the territory of Ukraine in the 15th century

2020 ◽  
pp. 12-16
Author(s):  
L. F. Kaskova ◽  
N. V. Yanko ◽  
O. O. Kulai ◽  
L. F. Chupryna ◽  
A. V. Artemyev
Keyword(s):  
Research Method ◽  
Periodontal Diseases ◽  
Main Group ◽  
Dental Status ◽  
Control Group ◽  
Dental Calculus ◽  
Alveolar Process ◽  
Skeletal Tissue ◽  
15Th Century ◽  
Ancient People

The condition of teeth in ancient populations living on the territory of Ukraine has been little studied. The aim of the work is to study the dental status of the 15th century Nogais, and to carry out a comparative analysis of the data obtained with the state of the dento-jaw system of medieval populations that lived on the territory of modern Ukraine in the 9th – early 15th centuries. The object of the study was 48 Nogai skeletons (main group) and 118 representatives of medieval cultures (control group). The research method was a method for analyzing the skeletal tissue of ancient people, developed by the authors. The prevalence and intensity of caries, the prevalence of dento-jaw anomalies, dental calculus and periodontal diseases were studied. Statistical analysis was performed using the Pearson χ2 test. It was found that the prevalence of dental caries in the main group is lower than in the control group (18.75 % and 37.28 % respectively, p<0.05). It was also found that this indicator significantly differed in men of both groups (p<0.05), while in women it did not differ (p>0.1). It was found that in the main group, compared with the control group, the frequency of primary adentia was higher (16.67 % and 6.68 % respectively, p<0.05), but the prevalence of anomalies in the position of individual teeth and occlusion was lower (4.17 % and 21.18 % respectively, p<0.05,). It was found that the prevalence of dental calculus in the main group is two times higher than in the control group (89.50 % and 41.0 % respectively, p<0.0001). Also, 15.0 % of Nogai men showed a decrease in the height of the alveolar process of the jaws, which is characteristic of periodontitis; in women, such changes were not found due to the low average age of survival. Thus, the 15th century Nogai population had a lower prevalence of caries and dento-maxillary anomalies than the medieval populations that lived on the territory of modern Ukraine in the 9th – early 15th centuries.

scholarly journals ASSESSMENT OF BONE METABOLISM IN PATIENTS WITH BISPHOSPHONATE OSTEONECROSIS OF THE JAWS

2017 ◽  
Vol 21 (4) ◽  
pp. 197-199
Author(s):  
Elena Mikhaylovna Spevak ◽  
D. Yu Khristoforando ◽  
A. B Davydov
Keyword(s):  
Bone Metabolism ◽  
Cancer Patients ◽  
Osteonecrosis Of The Jaw ◽  
Main Group ◽  
Control Group ◽  
Tartrate Resistant Acid Phosphatase ◽  
Type I ◽  
Bone Specific Alkaline Phosphatase ◽  
Osteonecrosis Of The Jaws ◽  
Bisphosphonate Osteonecrosis

The aim of the study was to evaluate bone metabolism in cancer patients with bisphosphonate osteonecrosis of the jaws. The study included 45 people of the main group (patients with cancer with osteonecrosis of the jaw in patients receiving bisphosphonates) and 25 in the control group (cancer patients treated with bisphosphonates, but did not have osteonecrosis of the jaw), which had a stabilization of the underlying disease. Bone metabolism was evaluated by the level of osteocalcin (OC), bone-specific alkaline phosphatase (bALP), aminoterminal of propeptide of procollagen type I (P1NP), tartrate-resistant acid phosphatase (TRAP5b), calcium (Cа), phosphorus (P) in blood serum before treatment and after 6 months. Compared to the average levels of marker patients of the main and control groups using the Mann-Whitney test for p < 0,05. A baseline level of СТХ (0,23±0,02 ng/ml) and OС (11,58±0,54 ng/ml) in the treatment group was significantly (p < 0.05) lower than control group (0,43±0,01 ng/ml and 17,94±0,83 ng/ml), and the level of osteocalcin in the main group (11,58±0,54 ng/ml) was on average below normal 2,59 times. Recorded significantly higher (p < 0,05) levels bALP (133,24±14,03 U/l) and TRAP5b (3,54±0,38 U/l) in patients with osteonecrosis compared with a control group (73,32±3,41 U/l and 3,12±0,12 U/l). Reliably detected differences in the levels of P1NP, Ca and P were not detected (p > 0,05). In the main group after 6 months of treatment was observed a tendency of growth of СТХ, TRAP5b, OK, bALP, P1NP, Ca, but only for the markers of resorption and СТХ, TRAP5b these differences were significant. Indicators of patients in the control group were stable and did not differ in the dynamics. The development of bisphosphonate osteonecrosis of the jaws is directly related to bone metabolism and occurs with predominance of the processes of bone resorption and inhibition of bone formation processes.

scholarly journals THE PREVALENCE OF PERIODONTAL TISSUE DISEASES IN YOUNG INDIVIDUALS ON THE BACKGROUND OF CROWDED TEETH

2018 ◽  
pp. 28-31
Author(s):  
A.V. Mandych
Keyword(s):  
Comparison Group ◽  
Periodontal Diseases ◽  
Adult Population ◽  
Study Groups ◽  
Main Group ◽  
Periodontal Tissue ◽  
Facial Skeleton ◽  
Old Patients ◽  
Periodontal Tissues ◽  
Upper Jaw

The abnormalities of maxillodental system take one of the leading places among diseases of the maxillofacial area. Thus, they are diagnosed more than in 50% cases among the younger population and in 30% cases among the adult population.   Most often, there are prerequisites for the incorrect position of individual teeth: anomalies are formed at the genetic level because of heredity of pathologies of size, amount, shape of teeth and size of the jaw bones of the facial skeleton. If the position of the teeth is incorrect, the periodontium retains the occlusal load of the functional injury. Therefore, the aim of our research was to study the prevalence of periodontal tissue diseases in young individuals on the background of crowded teeth. The material and research methods. The study was conducted on the base of Dental Center of Danylo Galytsky Lviv National Medical University during 2015−2017 years. 1146 people at the age from 18 to 44 years were examined. Every participant of research underwent general dental examination, as well as a special examination aimed at clarification of orthodontic treatment. The diagnosis of periodontal tissue diseases was made according to the classification of N. F. Danilevskyi and was determined using paraclinical indicators. The obtained results were worked out statistically using functions of MS Excel and Statistica 6. Results of the research and their discussion. The total number of the examined with orthodontic pathology was found on average in 77.24% of patients (885 people). At the same time, abnormalities of dental jaw system were not detected in about 261 (22.76%) of the examined. As a result of the conducted studies we found that among the examined without dental jaw abnormalities 38.89±.,32% of patients had intact periodontium, that was 1.6 times more for data in individuals with crowding − 23.73±2.00, p<0.01. At the same time, in patients of the main group the prevalence of periodontal tissue diseases was 1.2 times higher than in the examined of the comparative group (76.27±2.00% against 61.11±3.32%, respectively, p<0.01). It should be noted, that with the increase of the age of patients the prevalence of periodontal tissue diseases increased in both study groups, but in patients with crowded teeth this tendency was more pronounced. So, in the younger age group in patients with crowding the prevalence of periodontal diseases was 1.5 times higher in relation to the data of their peers from the comparison group (71.37±3.00% vs. 46.99±5.48%, p<0.01). In 27−35-year-old patients the prevalence of periodontal tissue diseases amounted to 72.38±4.03% of the examined of the main group and 65.62±5.94% of the examined of the comparison group, but the obtained data were not statistically significant, p>0.05. At the same time, in the patients of the main group aged 36−44 years the prevalence of periodontal tissue diseases was maximal and exceeded the value of their peers in the comparison group by 1.2 times (92.08±2.69% vs. 73.91±5.29%, respectively, p<0.01). The analysis of the obtained data allowed to assert that on average crowding of teeth on the upper jaw was found in 237 patients (52.55%) and on the lower jaw in 214 patients (47.45%). Thus, the maximum frequency of crowded teeth on the upper jaw was observed in the examined in the age range of 27−35 years, 60.16±4.41% of patients, with the minimum prevalence of this pathology in the youngest group (18−26 years), 49.34±4, 72%. The analysis of diagnostic structure of periodontal tissue diseases showed that inflammatory diseases of periodontal tissues (gingivitis, localized periodontitis) were found in patients with crowded teeth, on average 1.2 times more often than in patients without orthodontic pathology (42.42±1.88% vs. 36.33±3.54%, respectively, p<0.05). Conclusions. Thus, as a result of the conducted studies, higher prevalence of periodontal tissue diseases was proved in patients with crowding of teeth, which made progress in increasing the age of the examined than in patients without orthodontic pathology.

scholarly journals Improving of treatment of periodontal diseases in workers of the woodworking industry of the Chernivtsi region

2021 ◽  
Vol 106 (2) ◽  
pp. 28-35
Author(s):  
V. Batig ◽  
◽  
O. Tokar ◽  
I. Burdenyuk ◽  
◽  
...  
Keyword(s):  
Maintenance Therapy ◽  
Comparison Group ◽  
Periodontal Diseases ◽  
Main Group ◽  
Control Group ◽  
Treatment And Prevention ◽  
Group A ◽  
Group B ◽  
Periodontal Indices

Goal. Improving the scheme of treatment and prevention of periodontal diseases in workers of the woodworking industry of Chernivtsi region, who in the process of professional activity have long-term contact with unfavorable factors of the production environment. Materials and methods. 70 workers of the woodworking industry with diagnosed chronic generalized periodontitis of the I degree were treated (35 people – the main group (A); 35 people – comparison group (B)), age – from 25 to 45 years. To compare the results of laboratory studies, an additional survey of 25 healthy individuals of the same age with an intact periodontium were conducted. They formed the control group (C). Clinical examination of patients was performed according to standart methods: subjective (complaints, medical history, life history) and objective (examination, periodontal indices, determination of the level of gingival attachment). Laboratory methods of research included determination of urease and lysozyme activity in saliva, degree of dysbiosis of oral cavity. As maintenance therapy, patients of the main group were prescribed the proposed composition DEPE. Results. After the treatment, a significant improvement in the hygienic status of patients in both groups was observed, but difference between groups A and B in the indicators of oral hygiene after treatment was no statistically significant (pA2–B2 > 0.05). There was a significant improvement in periodontal indices after treatment in patients of both groups (PMA index according to C. Parma, bleeding index according to Muhlemann in Cowell I. modification, Russell periodontal index, PSR-test), but the indicators in patients of the main group were significantly better – pA2–B2 < 0.05. In patients of the main group (A) the level of attachment loss decreased by 1.83 times, comparison group (B) – by 1.71 times. The difference in levels of attachment loss after treatment between groups A and B is statistically significant (pA2–B2 < 0.05). The activity of the enzyme urease in patients of the main group (A) and comparison group (B) after treatment was significantly reduced (pA1–A2 < 0.001, pB1–B2 < 0.001), but only in the main group it reached the level in the control group (C) (pA2–C > 0.05). The level of lysozyme after treatment was significantly increased in patients of both observation groups (pA1–A2 < 0.001, pB1–B2 < 0.001), and reached the level of lysozyme in patients of the control group (C) (pA2–C > 0.05, pB2–C > 0.05). The degree of oral dysbiosis in patients of the main group (A) was significantly reduced by 5.43 times (pA1–A2 < 0.001), and its difference from the degree of dysbiosis in patients of the control group (C) is statistically insignificant (pA2–C > 0.05 ). The degree of oral dysbiosis in patients of the comparison group (B) was significantly reduced by 3.04 times (pB1–B2 < 0.001), but still remained significantly different from oral dysbiosis in patients of the control group (C) (pB2–C < 0.05). Conclusion. The proposed pharmacological composition DEPE is an effective antiseptic solution and can be used in the phase of maintenance therapy to improve the treatment and prevention of periodontal disease in workers of woodworking industry. Key words: decamethoxine, propolis, ethonium, generalized periodontitis, woodworking industry.

scholarly journals Hair Mercury Levels in Periodontal Patients in Comparison with Healthy Individuals

2014 ◽  
Vol 5 (3) ◽  
pp. 166-169 ◽  
Author(s):  
Soraya Khafri ◽  
Hamidreza Hasanjani Roushan ◽  
Hadi Parsian ◽  
Ramin Alijannia ◽  
Abbas Mosapour
Keyword(s):  
Chronic Periodontitis ◽  
Healthy Subjects ◽  
Periodontal Diseases ◽  
Mercury Level ◽  
Control Group ◽  
P Value ◽  
Healthy Individuals ◽  
Hair Mercury ◽  
Hair Samples ◽  
The Difference

ABSTRACT Introduction The clinical manifestation of periodontal diseases (such as gingivitis and chronic periodontitis) results from a complex interplay between the etiologic agents such as bacteria that present in the dental plaque, genetic factors, systemic diseases, smoking and exposure of some heavy metals, such as mercury. In this study, we aimed to evaluate hair mercury levels in healthy subjects in comparison with periodontal patients. Materials and methods One hundred twenty subjects were enrolled in this study. The included persons were divided into 3 groups: healthy subjects (n = 40), gingivitis (n = 40) and chronic periodontitis patients (n = 40). Hair samples were collected from occipital area of head. Total mercury levels were determined by atomic absorption spectrophotometry. Results The difference between mercury levels in three groups were statistically significant (p-value < 0.001). Mercury level in periodontitis patients was greater than the gingivitis group (p-value < 0.001). In addition the differences between mercury levels in periodontitis patients vs healthy individuals was significant (p-value = 0.048). The gingivitis patients had lower levels of mercury than the control group, but the difference was not significant (p-value = 0.170). Conclusion The results showed that the levels of mercury are to some extent differed in periodontal diseases in comparison with the healthy individuals. A study with larger sample size is needed for clarification of this issue. How to cite this article Roushan HH, Parsian H, Alijannia R, Mosapour A, Khafri S. Hair Mercury Levels in Periodontal Patients in Comparison with Healthy Individuals. World J Dent 2014;5(3):166-169.

scholarly journals Psychodiagnostics of suicide

2019 ◽  
pp. 3-9
Author(s):  
G. K. Dzub ◽  
V. A. Protzyc ◽  
V. A. Protzyc
Keyword(s):  
Depressive Disorders ◽  
Self Esteem ◽  
Psychological Research ◽  
Main Group ◽  
Control Group ◽  
Self Assessment ◽  
Suicidal Attempts ◽  
The Difference ◽  
High Level ◽  
And Control

An original hypothesis for the detection of suicidal readiness has been proposed: the dissociation between low self-esteem of personal qualitiesand high level of claims in behavior exists in all types of suicides. The main point is that suicide occurs in a situation where environmental conditions are appear to be completely incompatible with a person’s self-esteem; preserving the personality then the protective adaptive response of the personality is accomplished in the most radical way – self-destruction. Therefore, to detect readiness for suicide, you can use the methods of experimental psychological (psychodiagnostic) research. These are methods of self-assessment of a situation, that is, a tests assessing one's own merits and determining the level of claims in behavior. Discrepancies in the performance of these tests will reflect the degree of readiness for suicide. Confirmation has been obtained through clinical and experimental psychological research. On the material of 240 subjects, the modified methods of Dembo – Rubinstein and Hoppe were used. The main group consisted of 160 persons who committed suicidal attempts, of which 98 women and 62 men, average age (41.0 ± 9.7) years, including 86 with depressive disorders, 46 with neurotic disorders and 28 mentally healthy. In the control group there were 80 healthy individuals who did not commit suicidal attempts, with identical gender balance, average age and social status. The modification of the methods was that the results were presented in quantitative terms in points. In the main group, the dissociation indicators between the high level of claims and low self-esteem according to the methods of Dembo – Rubinstein and F. Hoppe were 46.8 ± 4.6, and in the control group – 27.00 ± 5.24 (P < 0,001). The difference between dissociation in the main and control groups is very significant (P < 0,0005), a score of 40–45 points indicates a suicidal risk, and 50–55 and more confidently point to the upcoming suicide attempt. As a result, the hypothesis is confirmed and a valid method of predicting suicide or assessing the degree of its risk arises; the method is suitable for practical use.

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