Abstract P417: Physical Activity, Physical Fitness and Leukocyte Telomere Length: The Cardiovascular Health Study

Circulation ◽  
2013 ◽  
Vol 127 (suppl_12) ◽  
Author(s):  
Luisa Soares-Miranda ◽  
Fumiaki Imamura ◽  
David S Siscovick ◽  
Nancy Swords Jenny ◽  
Annette L Fitzpatrick ◽  
...  

Background The influence of physical activity (PA) and fitness (PF) at older ages on changes in telomere length (TL), repetitive DNA sequences that may mark biologic aging, are not well established. Prior studies in older adults were cross-sectional, and few evaluated PF. Aim To investigate both cross-sectional and prospective associations of PA and PF with Leukocyte TL in older adults. Methods Among 582 adults age 73±5 y at baseline in CHS having serial LTL measures (leucocyte mean terminal restriction length) in 1992 and 1997, PA (walking pace, blocks, combined walking score; leisure time activity) and PF (15-ft walk, chair stands, grip strength) were assessed multiple times from 1989 to 1997. Cross-sectional associations were assessed using multivariable repeated-measures regression of cumulative average serial PA and PF measures from 1989 to 1992 against LTL in 1992; and cumulative averaged PA and PF from 1993 to 1997 against LTL in 1997. Longitudinal analyses assessed cumulative averaged PA and PF from 1989-92 against later changes in LTL from 1992-97; and changes in cumulative averaged PA and PF from 1989-92 to 1993-97 against changes in LTL from 1992-97. We evaluated all subjects, those without poor/fair self-reported health, and those without limited ADLs. Results Cross-sectionally, greater walking distance and chair test performance, but not other PA and PF measures, each associated with longer LTL ( P trend 0.007, 0.04 respectively). Lab measures of DNA integrity suggested measurable degradation that markedly attenuates ability to detect differences in LTL changes over time, especially over only 5 y. For example, baseline PA and PF from 1989-92 were unassociated with later changes in LTL. In contrast, changes in leisure time activity and chair test performance from 1992-97 were each inversely associated with LTL shortening. Conclusions Even late in life, certain PA and PF metrics are associated with longer LTL cross-sectionally and, even with likely substantial measurement error, with less LTL shortening over time.

2021 ◽  
pp. 089011712110525
Author(s):  
Namrata Sanjeevi

Purpose To assess the role of physical activity and healthcare access in mediating the association of acculturation with cardiometabolic health in Asian American adults with diabetes. Design Cross-sectional study. Setting National Health and Nutrition Examination Survey (NHANES) 2011–2018. Subjects Non-pregnant Asian American adults with doctor diagnosed diabetes. Measures Participants were classified into low, moderate, and high acculturation status. Self-reported leisure-time, work, and transportation-based physical activity were summed for overall physical activity. Health insurance, frequency of healthcare receipt, and glycohemoglobin (HbA1c) check in the past year indicated healthcare access. Cardiometabolic health indicators included HbA1c, total and high density lipoprotein-cholesterol, and systolic and diastolic blood pressure. Analysis Linear and logistic regression estimates, standardized using y-standardization, and assessed mediation of acculturation with cardiometabolic health. Results Low acculturation was significantly related to greater leisure-time inactivity odds [OR (95% CI) = 2.25 (1.05, 4.82)], overall insufficient activity [OR (95% CI) = 2.30 (1.12, 4.74)], and uninsured status [OR (95% CI) = 5.62 (1.55, 20.41)]. Asian Americans with low acculturation had significantly higher log HbA1c than those with high acculturation ( β ± SE = .078 ± .038); however, this association was not significant after adjusting for leisure-time activity. Leisure-time activity mediated 48.9% of acculturation and HbA1c association, and the indirect effect was statistically significant [estimate (95% CI) = .021 (.002, 0.047)]. Conclusions Results suggest that promoting sufficient leisure-time activity could improve glycemic control in least acculturated Asian Americans with diabetes.


2020 ◽  
Vol 32 (4) ◽  
pp. 717-721
Author(s):  
Bimba Wickramarachchi ◽  
Sidiah Siop ◽  
Bilesha Perera

There is a paucity of information on physical activity behaviour of older adults in Sri Lanka.  This study determined the physical activity status of urban-dwelling older adults in a district in the country. A cross sectional survey of 880 subjects (aged 60+ years) was conducted using the Global Physical Activity Questionnaire. The prevalence rates of physically inactive, sufficiently active and highly active were 21.5%, 78.5% and 52.7% respectively. Women were more active than men (Women, 80.9% versus men, 75.5%, p < 0.05). Activity at work accounted for the highest portion of physical activity as reported by the participants [Median = 2400 MET/Week, 95% CI: 240, 4800] followed by active transport [Median =120 MET/Week, 95% CI: 0, 560] and leisure-time activity [Median = 0 MET/Week, 95% CI: 0, 270]. Factors contributing for extensively engaging activity at work need further investigations and older adults should be encouraged to do leisure-time physical activities.


2012 ◽  
Vol 20 (1) ◽  
pp. 1-14 ◽  
Author(s):  
Mark W. Swanson ◽  
Eric Bodner ◽  
Patricia Sawyer ◽  
Richard M. Allman

Little is known about the effect of reduced vision on physical activity in older adults. This study evaluates the association of visual acuity level, self-reported vision, and ocular disease conditions with leisure-time physical activity and calculated caloric expenditure. A cross-sectional study of 911 subjects 65 yr and older from the University of Alabama at Birmingham Study of Aging (SOA) cohort was conducted evaluating the association of vision-related variables to weekly kilocalorie expenditure calculated from the 17-item Leisure Time Physical Activity Questionnaire. Ordinal logistic regression was used to evaluate possible associations while controlling for potential confounders. In multivariate analyses, each lower step in visual acuity below 20/50 was significantly associated with reduced odds of having a higher level of physical activity, OR 0.81, 95% CI 0.67, 0.97. Reduced visual acuity appears to be independently associated with lower levels of physical activity among community-dwelling adults.


2020 ◽  
Vol 48 (9) ◽  
pp. 030006052095689
Author(s):  
Saad M. Bindawas ◽  
Vishal Vennu ◽  
Ayidh M. Alqarni ◽  
Tariq A. Abdulrahman

Objective To assess physical performance (PP) and physical activity (PA) among older adults visiting primary healthcare centres (PHCCs) in Riyadh. Methods In this cross-sectional study, men and women (n = 74) aged ≥60 years were recruited from five PHCCs across Riyadh, Saudi Arabia, between 19 February and 6 August 2017. The Timed Up & Go test was used to assess PP. Self-reported PA was assessed using the Physical Activity Scale for the Elderly. Means and standard deviations were used to describe PP and PA scores across genders. A two-tailed independent samples t-test was used to estimate mean differences (MD) and 95% confidence intervals (CI) between genders. Results Men scored significantly lower than women on PP (MD: 2.11, 95% CI: 0.59 to 3.64) and PA (MD: −46.1, 95% CI: −80.96 to −11.25). Significant gender differences were observed for leisure time activities (MD: 17.35, 95% CI: 3.29 to 31.40), light household activities (MD: –10.86, 95% CI: –16.19 to –5.53) and heavy household activities (MD: –6.48, 95% CI: –11.73 to –1.23). Conclusions Men show significantly lower PP and PA than women. There are gender differences in leisure time activities and in light and heavy household activities.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S292-S292
Author(s):  
Rie Suzuki ◽  
Jennifer Blackwood ◽  
Shailee Shah ◽  
Sabah Ganai ◽  
Kimberly Warden

Abstract The built environment is commonly cited as a facilitator to local walking. Although health promotion programs targeting physical activity are available, few studies have investigated the associations of the perceived neighborhoods with the incidence of falls in the minority communities. Hence, the purpose of this preliminary study was to understand whether the perceived built environment influenced the fall experiences in older adults living in the underserved community. The preliminary cross-sectional survey was conducted at the regional health clinic in Flint, MI. Descriptive statistics and analysis of variance (ANOVA) were performed using SAS v8.4. The eligibility criteria included over 65 years old and Flint residents. Of 132 participants, the mean age was 69.75 (SD=5.00). The majority were female (68%), African Americans (80%), single, divorced or widowed (80%), and &gt; GED (84%). The ANOVAs supported that “had fallen in the past year” was associated with “stores are within easy walking distance,” “easy to walk to a transit stop” and “there is a dirt strip that separates the streets from the sidewalks.” The fall experience was more likely to associate with the sedentary lifestyle and the comorbidities such as diabetes, fatigues, muscle spasms, and chronic pain. To summarize, the built environment increased the incidence of falls in the past year. Those who had fallen had poor health conditions. Further studies are needed for older adults to engage in physical activity. It is essential to develop the age-friendly support systems and accommodations to local walking in this community.


Author(s):  
Mónica Machón ◽  
Kalliopi Vrotsou ◽  
Isabel Larrañaga ◽  
Itziar Vergara

The aim was to examine how proximity to facilities, as a component of community determinants, is associated with the health-related habits of functionally independent community-dwelling older adults. This was a cross-sectional study. Data were collected by face-to-face interviews. Participants were >65 years old, living in 15 municipalities of Gipuzkoa (Basque Country, Spain). Proximity to park-green spaces, cultural-sport centers, market-food stores, retirement associations, religious centers, primary care centers and hospitals was explored. Sociodemographic variables and health-related habits (diet, physical activity and self-perceived social life) were collected. Logistic regression models were performed. The sample comprised of 634 individuals (55% women; mean age: 74.8, SD 6.7 years). Older age (odds ratio-OR: 0.94, 95% CI: 0.91–0.97) was associated with lower physical activity, while being male (OR: 1.71, 95% CI: 1.08–2.68) and proximity to park-green spaces (OR: 1.64, 95% CI: 1.03–2.61) were related to more physical activity. Individuals with good self-perceived health (OR: 3.50, 95% CI: 1.82–6.74) and religious centers within walking distance (OR: 2.66, 95% CI: 1.40–5.04) had higher odds of a satisfactory social life. Encouraging the creation of park-green spaces and leisure centers near residential areas can assist in promoting physical activity and improving the social life of older adults.


2015 ◽  
Vol 12 (2) ◽  
pp. 200-207 ◽  
Author(s):  
Corneel Vandelanotte ◽  
Camille Short ◽  
Matthew Rockloff ◽  
Lee Di Millia ◽  
Kevin Ronan ◽  
...  

Background:A better understanding of how occupational indicators influence physical activity levels will aid the design of workplace interventions.Methods:Cross-sectional data were collected from 1194 participants through a telephone interview in Queensland, Australia. The IPAQ-long was used to measure physical activity. Multiple logistic regression was applied to examine associations.Results:Of participants, 77.9% were employed full-time, 32.3% had professional jobs, 35.7% were engaged in shift work, 39.5% had physically-demanding jobs, and 66.1% had high physical activity levels. Participants with a physicallydemanding job were less likely to have low total (OR = 0.25, 95% CI = 0.17 to 0.38) and occupational (OR = 0.17, 95% CI = 0.12 to 0.25) physical activity. Technical and trade workers were less likely to report low total physical activity (OR = 0.44, 95% CI = 0.20 to 0.97) compared with white-collar workers. Part-time (OR = 1.74, 95% CI = 1.15 to 2.64) and shift workers (OR = 1.86, 95% CI = 1.21 to 2.88) were more likely to report low leisure-time activity.Conclusions:Overall, the impact of different occupational indicators on physical activity was not strong. As expected, the greatest proportion of total physical activity was derived from occupational physical activity. No evidence was found for compensation effects whereby physically-demanding occupations lead to less leisure-time physical activity or vice versa. This study demonstrates that workplaces are important settings to intervene, and that there is scope to increase leisure-time physical activity irrespective of occupational background.


2010 ◽  
Vol 197 (5) ◽  
pp. 357-364 ◽  
Author(s):  
Samuel B. Harvey ◽  
Matthew Hotopf ◽  
Simon Øverland ◽  
Arnstein Mykletun

BackgroundPrevious studies have suggested that physical activity may have antidepressant and/or anti-anxiety effects.AimsTo examine the bidirectional relationship between physical activity and common mental disorders and establish the importance of context, type and intensity of activity undertaken.MethodA clinical examination of 40 401 residents of Norway was undertaken. Participants answered questions relating to the frequency and intensity of both leisure-time and workplace activity. Depression and anxiety were measured using the Hospital Anxiety and Depression Scale (HADS). Biological and social data were also collected.ResultsThere was an inverse relationship between the amount of leisure-time physical activity and case-level symptoms of depression. This cross-sectional association was only present with leisure-time (as opposed to workplace) activity and was not dependent on the intensity of activities undertaken. Higher levels of social support and social engagement were important in explaining the relationship between leisure activity and depression. Biological changes such as alterations to parasympathetic vagal tone (resting pulse) and changes to metabolic markers had a less important role.ConclusionsIndividuals who engage in regular leisure-time activity of any intensity are less likely to have symptoms of depression. The context and social benefits of exercise are important in explaining this relationship.


Author(s):  
Adel A. Alhusaini ◽  
Ganeswara Rao Melam ◽  
Syamala Buragadda

Background: The current study was done to assess the cross-cultural difference in physical activity and sedentary behavior among girls from culturally, environmentally, and geographically diverse countries residing in Saudi Arabia. Methods: This was a comparative cross-sectional study conducted among expatriate girls (N = 275), aged 9–16 years. Participants were from India (n = 65), Pakistan (n = 88), Egypt (n = 50), Sudan (n = 49), and other nationals (n = 23). They were randomly selected from different schools in Riyadh and their Body Mass Index (BMI) and screen time was assessed. Physical activity (PA) and leisure-time activity was assessed using Physical Activity Questionnaire for Older Children (PAQ-C) and the Godin-Shephard Leisure-Time Exercise Questionnaire (GSLTPAQ) respectively. Results: Out of 275, 65.8% were active and 34.2% were insufficiently active as per the GSLTPAQ, and half of them were moderately active and only 22.2% were extremely active as per PAQ-C. No statistical significant differences in their BMI status, screen time, or the levels of PA among expatriate girls. Conclusions: This study shows that the expatriate female school children in Saudi Arabia demonstrated a similar pattern in their BMI, sedentary time spent, and PA levels.


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