Abstract P355: Variable associations of dehydroepiandrosterone with cardiovascular risk factors in the Boston Puerto Rican Health Study

Introduction: Low blood levels of dehydroepiandrosterone sulfate (DHEAS) have been shown to have strong positive associations with diabetes, cardiovascular disease (CVD) mortality and stroke. However, the underlying pathways remain unclear, given limited data to systematically examine associations of DHEAS with CVD risk. In exploratory analyses we tested the association between CVD risk factors and DHEAS levels in a large population of Latinos. Methods: Among 1,450 participants in the Boston Puerto Rican Health Study between the ages of 45-75 years at baseline, socio-demographic, behavior, medical history, anthropometric and blood pressure data were collected at in-home interviews conducted by trained staff. A certified phlebotomist collected fasting blood samples. All samples were assayed for DHEAS, lipids, and C-reactive protein (CRP), HbA1c, insulin and glucose (GL). Spearman correlations were estimated between DHEAS and continuous CVD risk factors (lipids, systolic blood pressure [SBP] and diastolic blood pressure [DBP], CRP, GL, HbA1c, insulin, body mass index [BMI], waist circumference, physical activity and alcohol consumptions). We used robust multivariable linear regression models adjusted for potential confounders and intermediates with α=0.05 to estimate the association selected CVD risk factors and DHEAS levels. CVD risk factors were identified from a set of potential candidate predictors (age, female gender, history of heart disease, diabetes status, SBP, DBP, total and high density cholesterol [TC, HDL], triglycerides [TG], GL, CRP) using stepwise linear regression with an entry criterion of α=0.20 and exit criterion of α=0.10. Results: The mean DHEAS concentration among women was 70.7 μg/dL (s.d. 53.9; median=70.7) and among men was 119 μg/dL (s.d. 87.7; median=100). In age and sex adjusted Spearman correlations, TC, low density lipoprotein cholesterol, physical activity and alcohol were positively significantly correlated with DHEAS, while BMI and waist circumference were inversely correlated. In robust multivariable linear regression adjusted for potential confounders, age (-8.3; 95%CI:-10.0,-6.5; per 5 yrs), sex (β=-32.5; 95%CI:-38.4,-26.6) and TG (β=-0.5; 95%CI:-0.7,-0.2; per 10 mg/dl) were significantly inversely associated with DHEAS concentration, while TC (β=0.9; 95%CI:0.2,1.6;per 10 mg/dL) and GL (β=0.7; 95%CI:0.2, 1.2;per 10 mg/dL) were positively associated, albeit non-statistically significant. Adjustment for history of CVD, diabetes and BMI, only marginally attenuated these associations. Conclusions: Our data provide support for a significant association between TG levels and DHEAS concentrations even after adjustment for potential confounders and intermediates, which has been previously untested. These results suggest that DHEAS may work through lipid pathways.

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Blood pressure risk factors in healthy postmenopausal women: physical activity and hormone replacement

Journal of Applied Physiology ◽

10.1152/jappl.1997.82.2.652 ◽

1997 ◽

Vol 82 (2) ◽

pp. 652-660 ◽

Cited By ~ 21

Author(s):

Edith T. Stevenson ◽

Kevin P. Davy ◽

Pamela P. Jones ◽

Christopher A. Desouza ◽

and Douglas R. Seals ◽

...

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Blood Pressure ◽

Waist Circumference ◽

Postmenopausal Women ◽

Hormone Replacement ◽

Stepwise Multiple Regression ◽

Cvd Risk Factors ◽

Cvd Risk ◽

Physically Active

Stevenson, Edith T., Kevin P. Davy, Pamela P. Jones, Christopher A. Desouza, and Douglas R. Seals. Blood pressure risk factors in healthy postmenopausal women: physical activity and hormone replacement. J. Appl. Physiol. 82(2): 652–660, 1997.—The prevalence of cardiovascular disease (CVD) increases with advancing age in women, particularly after menopause. CVD risk is lower in physically active women relative to their sedentary peers, but the responsible mechanisms are not well understood. The aims of this study were to test the hypotheses that 1) physically active postmenopausal women demonstrate more favorable blood pressure (BP)-related risk factors for CVD than do sedentary healthy women and 2) women on hormone replacement therapy (HRT) also have more favorable levels of these CVD risk factors. BP-related CVD risk factors were measured in physically active women ( n = 18; age 55 ± 1 yr; n = 8 on HRT) and in healthy less-active controls ( n = 34; age 59 ± 1 yr; n = 17 on HRT). Maximal oxygen consumption was higher in the active group, whereas waist-to-hip ratio and waist circumference were lower (all P < 0.005). The active women demonstrated marginally lower (5–8 mmHg; P ≤ 0.10) levels of casual, 24-h, and daytime systolic BP (SBP). They also tended to have lower ( P = 0.11) daytime SBP loads (percentage of BP recordings >140/90 mmHg) and lower daytime and nighttime BP variabilities ( P = 0.04) and a reduced ( P < 0.007) SBP response to submaximal exercise. Women on HRT tended to have lower (3–4 mmHg; P = 0.07) levels of 24-h and nighttime diastolic BP (DBP) relative to the nonusers and smaller ( P < 0.04) daytime and 24-h DBP loads. Stepwise multiple regression indicated that waist circumference was the primary predictor of most of the SBP-related CVD risk factors while HRT use was the best predictor for DBP loads. These findings indicate that, in general, physically active postmenopausal women demonstrate more favorable SBP-related CVD risk factors relative to their less-active healthy peers, which may be mediated, in part, by their lower levels of abdominal adiposity. In addition, HRT use tends to be associated with lower levels of DBP-related CVD risk factors.

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Geographical profiles of cardiovascular risk and the risk factors in China: data from a nationwide population-based screening project

European Heart Journal ◽

10.1093/ehjci/ehaa946.2826 ◽

2020 ◽

Vol 41 (Supplement_2) ◽

Author(s):

C.Q Wu ◽

X Li ◽

J.P Lu ◽

B.W Chen ◽

Y.C Li ◽

...

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Blood Pressure ◽

Population Based ◽

Staple Food ◽

Cvd Risk Factors ◽

Cvd Risk ◽

Food Factor ◽

Rural And Urban ◽

Activity Factor

Abstract Background In China, an abundance of cardiovascular risk factors has contributed to the increasing prevalence of cardiovascular diseases (CVD), which caused almost 4 million deaths per year. However, comprehensive evidence on the geographical profiles of cardiovascular disease risk in China is lacking, as findings in prior studies have been limited to relatively small sample sizes, had incomplete regional coverage, or focused on a narrow risk factor spectrum. Purpose To compare the population CVD risk among different regions across China, and to describe the geographical distributions of CVD risk factors and their clusters throughout the nation. Methods In a nationwide population-based screening project covering 252 counties of China, standardized measurements were conducted to collect information on 12 major CVD risk factors. Individuals of high CVD risk were identified as those with previous CVD, or with a predicted 10-year risk of CVD greater than 10% according to the WHO risk prediction charts. We applied factor analysis to generate “clusters” that characterized the clustering of these risk factors, then explored their relationship with the local ambient temperature and per capital GDP. Results Among 983476 participants included, 9.2% were of high CVD risk, with a range of 1.6% to 23.6% across counties. Among the seven regions in China, the rate was relatively high in the Northeast (11.8%) and North China (10.4%), while low in the South China (7.2%) and Northwest (7.8%). We identified 6 clusters underlying CVD risk factors, including Obesity factor, Blood pressure factor, Staple food factor, Non-staple food factor, Smoking and alcohol factor, and Metabolic and physical activity factor (Figure). We found high risk regions were facing different leading challenges, like obesity and blood pressure for the North China, while unhealthy non-staple food for the Northeast. The South China, as the region with the lowest CVD risk, still had the highest prevalence of unhealthy staple food. Lower annual average ambient temperature was associated with higher risk in Blood pressure factor, Obesity factor and Non-staple food factor, but lower risk in Staple food factor and Metabolic and physical activity factor (p<0.001 for all), consistently between rural and urban. Higher per capital GDP was associated with lower risk in Non-staple food factor in urban and higher risk in Metabolic and physical activity factor in rural (p<0.05 for both). The correlation between per capital GDP and Smoking and alcohol factor differed significantly between in rural and urban regions (p=0.042). Conclusions The geographical profile of CVD risk in China is complex - population risk levels varied substantially across regions, which were contributed by different risk factors. China needs geographically targeted intervention strategies considering environmental and socio-economic factors to control CVD risk and reduce the burden related to CVD. Geographical disparity of risk clusters Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): The National Key Research and Development Program from the Ministry of Science and Technology of China; the CAMS Innovation Fund for Medical Science

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Evaluation of a 10-week lifestyle and weight management programme on cardiovascular disease risk factors in a group of people living with obesity referred from a specialist bariatric clinic

European Journal of Cardiovascular Nursing ◽

10.1093/eurjcn/zvab060.061 ◽

2021 ◽

Vol 20 (Supplement_1) ◽

Author(s):

A Harris ◽

D Keegan ◽

S Seery ◽

D Dunne ◽

Z Mc Crudden ◽

...

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Blood Pressure ◽

Type 2 Diabetes ◽

Lifestyle Modification ◽

Interdisciplinary Team ◽

Cvd Risk Factors ◽

Cvd Risk ◽

Risk Factor Reduction

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Health Service Executive Health and Wellbeing, Saolta University Healthcare Group OnBehalf Croí the West of Ireland Cardiac Foundation, Galway, Ireland and the National Institute for Prevention and Cardiovascular Health Introduction People living with obesity are at an increased risk of cardiovascular disease (CVD). While development of obesity is multifactorial, lifestyle modification is fundamental to obesity treatment and risk factor reduction. We sought to measure the effects of a structured lifestyle modification programme on the physical and mental health of people living with obesity. Purpose This study investigated the impact of a 10-week, community based, lifestyle modification programme on CVD risk factors in people living with obesity (BMI ≥35kg/m2 with a co-morbidity or BMI ≥40kg/m2) who were referred from a specialist bariatric service. Methods Delivered by an interdisciplinary team (Nurse, Dietitian & Physiotherapist) the programme included weekly group-based exercise sessions and health promotion workshops. A wide range of topics were addressed in workshops, including nutrition, food labels, emotional eating, physical activity, sedentary behaviour, stress management and CVD risk factor reduction. Outcomes were measured at initial and end of programme assessments. Results 1122 people participated in the intervention between 2013 and 2019 with 78% (n = 877) completing the programme. At initial assessment 26.7% of participants had a diagnosis of type 2 diabetes; 37.3% were at high or very high risk of CVD; 44.7% were hypertensive and 31.4% had a history of depression. Mean BMI was 47.0kg/m2 with 56.4% of participants having a BMI >45kg/m2. The intervention had significant positive impacts on key outcomes such as psychosocial health, lipid profiles, blood pressure, adiposity and cardiovascular fitness. One of the most significant outcomes observed was the improvement in psycho-social health. Scores of anxiety and depression, assessed using the HADS, decreased by 1.5 and 2.2 points respectively (p <0.001). Mean EQ-VAS score increased by 11 points (p <0.001). There were significant changes in total cholesterol levels with a mean reduction in total cholesterol from 4.69mmol/l to 4.54mmol/l (p <0.001) and LDL cholesterol from 2.79mmol/l to 2.64mmol/l (p <0.001). There were also significant improvements in blood pressure with mean systolic blood pressure reducing by 15.7mmHg (p <0.001) and diastolic blood pressure reducing by 1.4mmHg (p <0.001). For people with type 2 diabetes, there was an increase in those achieving the recommended HbA1c target (<53mmol/l) from 47.6% to 57.4% (p <0.001). Mean reduction in bodyweight was 2.0kg (p <0.001), with 27.2% achieving a weight loss of >3% of initial bodyweight. The percentage of participants achieving the recommended physical activity guidelines increased by 31% (p <0.001). Conclusions A lifestyle modification programme delivered by an interdisciplinary team, aimed at individuals living with obesity, is not only acceptable to participants but also significantly reduces CVD risk factors. These findings should influence the design of future programmes and healthcare policies in Ireland and abroad.

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Abstract 13901: Elevated Cardiovascular Risk Factors among Appalachian Women with a History of Pregnancy Complications

Circulation ◽

10.1161/circ.130.suppl_2.13901 ◽

2014 ◽

Vol 130 (suppl_2) ◽

Author(s):

Rebecca L Dekker ◽

Kristin B Ashford ◽

Terry A Lennie ◽

Misook L Chung ◽

Martha Biddle ◽

...

Keyword(s):

Risk Factors ◽

Waist Circumference ◽

Pregnancy Complications ◽

Tobacco Smoke Exposure ◽

Modifiable Risk Factors ◽

Cvd Risk Factors ◽

Cvd Risk ◽

Appalachian Women ◽

Induced Hypertension ◽

History Of

Introduction: A growing body of evidence links complications of pregnancy (gestational diabetes, preeclampsia, and pregnancy-induced hypertension) with double the risk of future cardiovascular disease (CVD) related death in affected women. However, little is known about which CVD risk factors are more prominent among women who have experienced pregnancy complications. Purpose: Compare the presence of modifiable CVD risk factors among women with and without a self-reported history of pregnancy complications living in Appalachian Kentucky- an area with the highest rate of CVD mortality in the U.S. Methods: Rural Kentucky Appalachian women (n = 122, 97% Caucasian, 42 ± 12 years) engaged in a comprehensive measurement of CVD risk factors including body mass index (BMI), waist circumference, blood pressure, A1C, lipid profile (total cholesterol, triglycerides, HDL, and LDL), tobacco smoke exposure (objectively measured with urine cotinine), depression (Patient Health Questionnaire-9), and anxiety (Brief Symptom Inventory). We used independent t-tests and chi-square analysis to compare risk factors between women with and without a history of pregnancy complications. Results: One-fourth of the sample had one or more pregnancy complications: gestational diabetes (8.2%), preeclampsia (6.6%) and pregnancy-induced hypertension (15.6%). Women with at least one pregnancy complication had a higher average BMI (33.4 vs. 30.4, p = .014), larger waist circumference (42.8 vs. 39.1 cm, p = .006), and a higher proportion with moderate to severe symptoms of depression (27.6% vs. 15.9%, p = .02) compared to women without a history of pregnancy complications. There were no differences between groups in systolic or diastolic blood pressure, A1C levels, lipid profiles, tobacco smoke exposure, or anxiety. Conclusions: Women with a history of pregnancy complications have several modifiable risk factors- higher BMI, higher waist circumference, and higher levels of depression- that could constitute a link between past pregnancy complications and their risk of future CVD death. Pinpointing which modifiable risk factors are elevated in these women will help us develop self-management interventions to prevent the development of CVD in this high-risk population.

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Effects of Training and Detraining on Physical Fitness, Physical Activity Patterns, Cardiovascular Variables, and HRQoL after 3 Health-Promotion Interventions in Institutionalized Elders

International Journal of Family Medicine ◽

10.1155/2010/486097 ◽

2010 ◽

Vol 2010 ◽

pp. 1-10 ◽

Cited By ~ 17

Author(s):

Alexandrina Lobo ◽

Joana Carvalho ◽

Paula Santos

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Blood Pressure ◽

Physical Fitness ◽

Dynamic Balance ◽

Cvd Risk Factors ◽

Cvd Risk ◽

Lower Strength ◽

Prospective Longitudinal ◽

Cardiovascular Variables

The purpose of this study is to assess the effects of different strategies of health on the levels of physical activity (PA), physical fitness (PF), cardiovascular disease (CVD) risk factors and quality of life (QoL) of the institutionalized elderly. Concurrently studies were made of the effect of detraining on these same variables. In this investigation we carried out a prospective longitudinal study with an experimental design, with 1 year plus 3 months of a detraining period. Methodology. (a) A questionnaire with socio-demographic characteristics and a QoL scale (MOS SF-36); (b) Functional Fitness Test to assess PF; (c) An MTI Actigraph to evaluate the PA; (d) Biochemical analysis of blood, blood pressure and bio-impedance. The Main Results Indicated That: (i) ST significantly improved strength and body flexibility and AT the aerobic endurance, agility/dynamic balance and lower strength and flexibility; (ii) Implications of detraining were more evident on the PA groups in the lower body flexibility, which is associated with agility/dynamic balance and lower strength in the AT group; (iii) Cardiovascular variables improved significantly especially blood pressure, cholesterol and glucose in the ST and HDL in the AT group; not having undergone significant changes with the detraining. The results of this thesis contribute positively to highlight the importance of PA in the promotion of health, prevention and reduction of CVD risk factors and the improvement of the PF and QoL.

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Risk Factors of Cardiovascular Disease among Ghanaian Police Officers

Cardiology and Angiology An International Journal ◽

10.9734/ca/2019/v8i430109 ◽

2019 ◽

pp. 1-9

Author(s):

Miriam Essien ◽

Herman Erick Lutterodt ◽

Reginald Adjetey Annan

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Cardiovascular Disease ◽

Waist Circumference ◽

Diastolic Blood Pressure ◽

Police Officers ◽

Density Lipoprotein ◽

Dietary Factors ◽

Cvd Risk Factors ◽

Cvd Risk

Background: Cardiovascular diseases continue to be a global public health burden among occupational groups like Police officers. Police officers play important roles to ensure law and order in countries. However, the nature of police work exposes them to violence and stress. Again, irregular food habits, irregular exercise, inadequate sleep, smoking and drinking are lifestyles which makes police officers prone to high incidence of cardiovascular disease (CVD). Aim: This study looked at the prevalence of CVD risk factors among police officers in Kumasi, Ghana. Study Design: Cross- sectional. Place and Duration of study: Ashanti Regional Police Headquarters, Kumasi, Ghana, between September, 2017 to July, 2018. Methodology: Weight, height, Body Mass Index (BMI), waist circumference, lipid profile, systolic and diastolic blood pressure of 120 officers were measured. Additionally, lifestyle and dietary factors such as exercise and intake of fruits of Police officers were assessed. Data were analyzed by SPSS version 22.0. Results: Slightly more than half (63, 52.5%) of the officers were females and the remaining (57,47.5%) were males. The mean of the various CVD risk factors among the total study participants are as follows; BMI 28.184±4.461 kg/m2, waist circumference 92.702±10.941 cm, systolic blood pressure (SBP) 128.121±17.047 mmHg, diastolic blood pressure (DBP) 85.569±10.854 mmHg, fasting blood sugar 5.387±1.756 mmol/l, high density lipoprotein (HDL) 1.546±0.211 mmol/l, low density lipoprotein 2.321±0.706 mmol/l (LDL) and total cholesterol (TC) 4.362±0.906 mmol/L. Prevalence of obesity among male and female officers were 43.9% and 36.5% respectively. With regards to hypertension, policemen and women recorded 31.6% and 20.6% respectively and dyslipidemia among males and females were 43.9% and 85.7% respectively. Conclusion: The officers were generally overweight, with over a quarter having hypertension and about two-thirds having dyslipidemia, making their risk for CVDs high. Further studies to elucidate the causes are required, routine medical screening and nutritional support are recommended.

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0400 Habitual Sleep, Circadian Misalignment, and Cardiovascular Risk Factors Among Late Adolescents

SLEEP ◽

10.1093/sleep/zsaa056.397 ◽

2020 ◽

Vol 43 (Supplement_1) ◽

pp. A153-A153

Author(s):

X Ji ◽

Y Wang ◽

J Saylor ◽

F Patterson ◽

L Ruggiero

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Cardiovascular Risk ◽

Waist Circumference ◽

Sleep Duration ◽

Late Adolescents ◽

Cvd Risk Factors ◽

Cvd Risk ◽

Circadian Misalignment ◽

High Bmi

Abstract Introduction Emerging evidence suggests the potential role of sleep in cardiovascular disease (CVD) risk. Sleep variability and circadian misalignment may represent understudied sleep dimensions, particularly among late adolescents. This study investigated the associations of habitual sleep, circadian misalignment, night-to-night sleep variability with CVD risk factors among late adolescents. Methods Using a cross-sectional design, we enrolled 58 healthy, college students (19.22±1.06 years old). Participants completed a 7-day sleep diary, the Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale. Circadian misalignment was assessed using the weekend-weekday differences in sleep duration and midsleep time. Sleep variability was calculated as intra-individual standard deviation of sleep durations. The number of CVD risk factors (BMI, waist circumference, blood pressure, fasting glucose and lipid profile) above subclinical/clinical thresholds was used as a proxy of overall risk. Logistic and generalized linear regression tested the relationships. Results Forty-two participants (73%) had at least one elevated CVD risk factors and 19 (34%) were short sleepers (<7 h). On average, the midsleep shifted 54 minutes later on weekends and the intraindividual sleep variability was 1.31 hours. After controlling for age, gender and race, there was a trend towards higher overall CVD risk (β=0.45±0.22, p=0.05) with a greater weekend-weekday discrepancy in sleep duration. For each CVD risk factor, a greater discrepancy in weekend-weekday midsleep times (OR=2.29±0.82, p=0.02) was estimated to increase the odds of high blood pressure. Participants with greater discrepancy in weekday-weekend sleep durations (OR=1.58±0.41, p=0.03) or excessive daytime sleepiness (OR=4.68±3.38, p=0.03) were more likely to have high BMI. Worse sleep quality (higher PSQI scores) was associated with high BMI (OR=1.36±0.19, p=0.03) and waist circumference (OR=1.40±0.24, p=0.04). Conclusion This study suggests that circadian misalignment, compared with other sleep characteristics, better predicts cardiovascular risk among late adolescents. Future research is needed to examine the interaction among circadian misalignment, sleep variability and sleep duration on CVD risk. Support American Nurse Foundation 18A01422

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Abstract P282: Cross-sectional Relationship Between Physical Activity and Cardiovascular Risk Factors in Kidney Transplant Patients: A Baseline Examination of the Folic Acid for Vascular Outcome Reduction in Transplantation (FAVORIT) Trial

Circulation ◽

10.1161/circ.137.suppl_1.p282 ◽

2018 ◽

Vol 137 (suppl_1) ◽

Author(s):

Augustine W Kang ◽

Carol E Garber ◽

Charles B Eaton ◽

Patricia M Risica ◽

Andrew G Bostom

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Multiple Regression ◽

Kidney Transplant ◽

Chronically Ill ◽

Cvd Risk Factors ◽

Cvd Risk ◽

Cross Sectional ◽

Hierarchical Multiple Regression ◽

History Of

Introduction: Data characterizing the potential relationship between physical activity and cardiovascular disease (CVD) risk factors in kidney transplant recipients (KTRs) are limited in the published literature. Accordingly, we sought to: (1) describe the levels of physical activity (PA) in KTRs; and (2) analyze the associations between PA levels and CVD risk factors in KTRs. We report the largest cross-sectional study of PA levels and CVD risk factors in KTRs to date. Methods: Baseline data from the large multiethnic, multicenter trial (FAVORIT) were examined with n = 4034 participants (37% female; mean age 51.9 ± 9.4 years; 75% White; 97% with stage 2T-4T Chronic Kidney Disease; 20% with prevalent CVD). PA was categorized in tertiles (low, moderate, high) derived from a modified PA summary score from the Yale Physical Activity Survey (YPAS). CVD risk factors were examined across levels of PA by ANOVA, Kruskal-Wallis rank test and hierarchical multiple regression modeling. Results: Collectively, participants were less active (mean YPAS 39.9 ± 20.6) compared to similar-aged rheumatoid arthritis (48 ± 21) and osteoarthritis (51 ± 20) samples from other studies. Participants in the “high” PA tertile reported more vigorous PA and walking, compared to participants in moderate and low tertiles (both p < .001). No differences were observed for daily household, occupational or sedentary activities (i.e., standing, sitting, moving about) across PA tertiles. More participants in the “low” PA tertile were overweight/obese and had a history of prevalent diabetes and/or CVD, compared with more active participants (all p < .001). Hierarchical multiple regression revealed that lower age ( p = .002), having a cadaveric donor source ( p = .006), shorter transplant vintage ( p = .025), lower pulse pressure ( p < .001) and no history of diabetes ( p < .001) were significantly associated with higher PA scores. Conclusion: KTR participants appear to be less active than samples of other chronically ill participants. In our data, lower levels of PA were positively associated with the presence of most CVD risk factors in the KTR population. Furthermore, higher PA levels were associated with younger age and variables associated with more positive KTR outcomes. Future longitudinal analyses of this unique KTR cohort will examine whether higher PA levels are associated with reduced risk for the development of hard, centrally-adjudicated CVD outcomes.

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Abstract P309: The Role of Traumatic Stress in Association Between Physical Activity and Cardiovascular Disease Risk Factors Among Hispanic/Latino Adults: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) Sociocultural Ancillary Study

Circulation ◽

10.1161/circ.135.suppl_1.p309 ◽

2017 ◽

Vol 135 (suppl_1) ◽

Author(s):

Priscilla Vasquez ◽

David X Marquez ◽

Linda C Gallo ◽

Maria Argos ◽

Violeta Carrion ◽

...

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Traumatic Stress ◽

Disease Risk ◽

Cardiovascular Disease Risk ◽

Health Study ◽

Cvd Risk Factors ◽

Cvd Risk ◽

Ancillary Study ◽

Increased Risk

Background: Physical activity ( PA ) is associated with lower risk, and chronic stress with increased risk of CVD risk factors ( RFs ) such as hypertension ( HTN ) or type 2 diabetes. Little is known about potential interactions between PA and traumatic stress ( TS ) in relation to CVD risk factors. Objective: To assess whether the association of PA with CVD RFs is modified by the presence of traumatic stress ( TS ). Methods: Cross-sectional data from 4,169 adults ages 18-74 in 2008-11, who participated in the HCHS/SOL Sociocultural Ancillary Study and had complete information on key variables, were analyzed using complex survey design methods. TS was assessed by self-reported lifetime exposure to traumatic events; scores were categorized into tertiles based on number of stressors: low=0-1; intermediate=2; high=≥3. PA was assessed by the Global PA Questionnaire and grouped into 4 levels: inactive, low, intermediate, and high activity. CVD RFs included HTN, obesity, diabetes, smoking, and hypercholesterolemia. Multivariate logistic regression was used for analyses. Results: Compared to high PA levels, intermediate PA was significantly associated with HTN, inactivity was associated with obesity, and inactivity and intermediate PA were associated with diabetes ( Table ). Significant interaction between PA with TS was observed for HTN (p<0.001) but not for other CVD RFs. For effect modification by TS, among persons with low TS, intermediate PA was associated with 2.1 times higher odds of HTN vs. high PA levels. Among those with intermediate TS, low PA was associated with 2.3 times higher odds of HTN, and among those with high TS, inactivity was associated with 2.1 times higher odds of HTN vs. high PA levels. Conclusion: A statistical interaction was observed between traumatic stress and physical activity among those with hypertension (but not with other CVD risk factors), and the odds of HTN varied by TS. Further evaluation is needed to determine physical activity recommendations to prevent hypertension among those with traumatic stress.

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Dietary fat Intake Had a Different Influence on Body Mass Index in Active and Inactive Subjects: a Cross-Sectional Study

Journal of Health Sciences ◽

10.17921/2447-8938.2020v22n2p164-170 ◽

2020 ◽

Vol 22 (2) ◽

pp. 164-170

Author(s):

Ana Gabriella Pereira Alves ◽

Mário Flávio Cardoso Lima ◽

Maria Sebastiana Silva

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Blood Pressure ◽

Nutrient Intake ◽

Cross Sectional Study ◽

Sectional Study ◽

Cvd Risk Factors ◽

Cvd Risk ◽

Cross Sectional ◽

Energy And Nutrient Intake

The understanding of cardiovascular disease (CVD) risk factors and their association with food and physical activity is not yet completely clear. This study aimed to evaluate the association between CVD risk factors with dietary intake, according to the physical activity level. A cross-sectional study was conducted with Brazilian individuals attended by the Public Health System. Demographic, blood pressure, physical activity practice, anthropometry and food intake data were collected and evaluated. Of the 83 participants, 61.4% were active. No difference were observed in the frequency of CVD risk factors, anthropometric data, blood pressure, estimated energy requirement, energy and nutrient intake between the active and inactive subjects (p ≥ .05). There was also no difference in the frequency of energy and nutrient intake adequacy between groups (p ≥ .05). Among the inactive subjects, it was found that the consumption of total (OR: 1.021, p = .035) and saturated (OR: 1.060, p = .033) fat was predictor of being overweight, with no relationship between food intake and the risk factors for CVD when the total participants or active individuals were considered (p ≥ .05). No difference was observed in the frequency of CVD risk factors between active and inactive individuals, however, total and saturated fat consumption increased the chance of being overweight among the inactive individuals. Keywords: Cardiovascular Diseases. Food Consumption. Exercise. Body Weight. Health Systems. Resumo O conhecimento da associação entre os fatores de risco para doenças cardiovasculares com a alimentação e atividade física ainda não está totalmente elucidada. Este estudo teve como objetivo avaliar a associação entre os fatores de risco cardiovascular e o consumo alimentar, segundo o nível de atividade física. Foi realizado um estudo transversal com individuos brasileiros atendidos pelo Sistema Único de Saúde. Foram coletados e avaliados dados demográficos, pressão arterial, prática de atividade física, antropometría e consumo alimentar. Dos 83 participantes, 61,4% eram ativos. Não foi observado diferença na frequência dos fatores de risco cardiovascular, dados antropométricos, pressão arterial, estimativa da necessidade energética, consumo de energía e nutrientes entre os individuos ativos e inativos (p ≥ 0,05). Também não houve diferença na frequência de adequação no consumo de energia e nutrientes entre os grupos (p ≥ 0,05). Entre os participantes inativos, observou-se que o consumo de gordura total (OR: 1,021; p = 0,035) e saturada (OR: 1,060; p = 0,033) foram preditores do sobrepeso, sem relação entre o consumo alimentar e os fatores de risco cardiovascular quando se considerou todos os participantes ou apenas os indivíduos ativos (p ≥ 0,05). Não foi observado diferença na frequência dos fatores de risco cardiovascular entre os sujeitos ativos e inativos, entretanto o consumo de gordura total e saturada aumentou a chance de sobrepeso entre os indivíduos inativos. Palavras-chave: Doenças Cardiovasculares. Consumo de Alimentos. Exercício Físico. Peso Corporal. Sistemas de Saúde.

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