Abstract P314: Physical Activity-Mediated Associations of Perceived Neighborhood Violence and Problems on Depressive Symptoms Among Jackson Heart Study Participants

Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Kosuke Tamura ◽  
Steven D Langerman ◽  
Stephanie L Orstad ◽  
Sam J Neally ◽  
Marcus R Andrews ◽  
...  
Keyword(s):  
Physical Activity ◽  
Depressive Symptoms ◽  
Social Cohesion ◽  
Indirect Effects ◽  
Epidemiological Studies ◽  
Jackson Heart Study ◽  
Neighborhood Violence ◽  
Community Based ◽  
Heart Study ◽  
Study Participants

Introduction: Little is known about whether links between perceived neighborhood social environment (PNSE) and depressive symptoms are mediated by physical activity (PA) levels. Hypothesis: We tested the hypotheses that total PA mediates relations between PNSE and depressive symptoms. Methods: We used Jackson Heart Study (JHS) baseline data. JHS is a prospective, community-based study of African Americans in the Jackson, MS (valid samples=2082; M age 52.4 years; 64% female). PNSE variables included neighborhood violence, problems (higher value=more violence or problems), and social cohesion (higher value=more cohesion). Depressive symptoms were measured by the Center for Epidemiological Studies Depression (CES-D) scale. Validated total PA, based on active living, sport, and work indices, was tested as the mediator. Linear regressions with bootstrap-generated 95% bias-corrected confidence intervals (BC CIs) were estimated using SAS 9.4 to test for significant unstandardized indirect effects, controlling for all covariates. Results: Participants had a mean depressive symptoms score of 10.8 ( SD =8.1). Neighborhood violence and problems were indirectly related to depressive symptoms via total PA ( β for indirect effects=.21, 95% BC CI =.02, .48 and .13, 95% BC CI =.01, .32, respectively). That is, higher violence and problems were related to lower total PA. In turn, higher total PA was associated with lower depressive symptoms ( Figure 1 ). Neighborhood violence and problems also were directly related to depressive symptoms ( p <.05). Yet, social cohesion was not indirectly or directly related to depressive symptoms. Conclusions: Higher perceived neighborhood violence and problems were positively related to depressive symptoms. These associations may be explained in part via lower total PA levels. Future interventions to reduce depressive symptoms attributed to neighborhood issues should consider PA promotion in conjunction with community efforts to reduce neighborhood violence and problems.

scholarly journals Discrimination and Leukocyte Telomere Length by Depressive Symptomatology: The Jackson Heart Study

Healthcare ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 639
Author(s):  
LáShauntá M. Glover ◽  
Crystal W. Cené ◽  
Alexander Reiner ◽  
Samson Gebreab ◽  
David R. Williams ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Depressive Symptomatology ◽  
Perceived Discrimination ◽  
Epidemiological Studies ◽  
Active Coping ◽  
Jackson Heart Study ◽  
Passive Coping ◽  
Coping Responses ◽  
Heart Study ◽  
Mean Differences

Background: Psychosocial stressors, such as perceived discrimination and depressive symptoms, may shorten telomeres and exacerbate aging-related illnesses. Methods: Participants from the Jackson Heart Study at visit 1 (2000–2004) with LTL data and Center for Epidemiological Studies-Depression (CES-D) scores (n = 580 men, n = 910 women) were utilized. The dimensions of discrimination scores (everyday, lifetime, burden of lifetime, and stress from lifetime discrimination) were standardized and categorized as low, moderate, and high. Coping responses to everyday and lifetime discrimination were categorized as passive and active coping. Multivariable linear regression analyses were performed to estimate the mean difference (standard errors-SEs) in LTL by dimensions of discrimination and coping responses stratified by CES-D scores < 16 (low) and ≥ 16 (high) and sex. Covariates were age, education, waist circumference, smoking and CVD status. Results: Neither everyday nor lifetime discrimination was associated with mean differences in LTL for men or women by levels of depressive symptoms. Burden of lifetime discrimination was marginally associated with LTL among women who reported low depressive symptoms after full adjustment (b = 0.11, SE = 0.06, p = 0.08). Passive coping with lifetime discrimination was associated with longer LTL among men who reported low depressive symptoms after full adjustment (b = 0.18, SE = 0.09, p < 0.05); and active coping with lifetime discrimination was associated with longer LTL among men who reported high depressive symptoms after full adjustment (b = 1.18, SE = 0.35, p < 0.05). Conclusions: The intersection of perceived discrimination and depressive symptomatology may be related to LTL, and the effects may vary by sex.

scholarly journals The impact of neighborhood on physical activity in the Jackson Heart Study

2016 ◽  
Vol 90 ◽  
pp. 216-222 ◽  
Author(s):  
Jennifer C. Robinson ◽  
Sharon B. Wyatt ◽  
Patricia M. Dubbert ◽  
Warren May ◽  
Mario Sims
Keyword(s):  
Physical Activity ◽  
Jackson Heart Study ◽  
Heart Study ◽  
The Impact

scholarly journals Physical activity in early adolescence predicts depressive symptoms 3 years later: A community-based study

2020 ◽  
Vol 277 ◽  
pp. 825-830
Author(s):  
Johan Isaksson ◽  
Eva Noren Selinus ◽  
Cecilia Åslund ◽  
Kent W Nilsson
Keyword(s):  
Physical Activity ◽  
Depressive Symptoms ◽  
Early Adolescence ◽  
Community Based

scholarly journals Total Antioxidant Performance Is Associated with Diet and Serum Antioxidants in Participants of the Diet and Physical Activity Substudy of the Jackson Heart Study

2009 ◽  
Vol 139 (10) ◽  
pp. 1964-1971 ◽  
Author(s):  
Sameera A. Talegawkar ◽  
Giangiacomo Beretta ◽  
Kyung-Jin Yeum ◽  
Elizabeth J. Johnson ◽  
Teresa C. Carithers ◽  
...  
Keyword(s):  
Physical Activity ◽  
Jackson Heart Study ◽  
Heart Study ◽  
Diet And Physical Activity ◽  
Total Antioxidant

scholarly journals Association of Habitual Physical Activity With Home Blood Pressure in the Electronic Framingham Heart Study (eFHS): Cross-sectional Study

10.2196/25591 ◽  
2021 ◽  
Vol 23 (6) ◽  
pp. e25591
Author(s):  
Mayank Sardana ◽  
Honghuang Lin ◽  
Yuankai Zhang ◽  
Chunyu Liu ◽  
Ludovic Trinquart ◽  
...  
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Habitual Physical Activity ◽  
Step Count ◽  
Daily Step ◽  
Community Based ◽  
Cross Sectional ◽  
Heart Study ◽  
Daily Step Count ◽  
The Mean

Background When studied in community-based samples, the association of physical activity with blood pressure (BP) remains controversial and is perhaps dependent on the intensity of physical activity. Prior studies have not explored the association of smartwatch-measured physical activity with home BP. Objective We aimed to study the association of habitual physical activity with home BP. Methods Consenting electronic Framingham Heart Study (eFHS) participants were provided with a study smartwatch (Apple Watch Series 0) and Bluetooth-enabled home BP cuff. Participants were instructed to wear the watch daily and transmit BP values weekly. We measured habitual physical activity as the average daily step count determined by the smartwatch. We estimated the cross-sectional association between physical activity and average home BP using linear mixed effects models adjusting for age, sex, wear time, antihypertensive drug use, and familial structure. Results We studied 660 eFHS participants (mean age 53 years, SD 9 years; 387 [58.6%] women; 602 [91.2%] White) who wore the smartwatch 5 or more hours per day for 30 or more days and transmitted three or more BP readings. The mean daily step count was 7595 (SD 2718). The mean home systolic and diastolic BP (mmHg) were 122 (SD 12) and 76 (SD 8). Every 1000 increase in the step count was associated with a 0.49 mmHg lower home systolic BP (P=.004) and 0.36 mmHg lower home diastolic BP (P=.003). The association, however, was attenuated and became statistically nonsignificant with further adjustment for BMI. Conclusions In this community-based sample of adults, higher daily habitual physical activity measured by a smartwatch was associated with a moderate, but statistically significant, reduction in home BP. Differences in BMI among study participants accounted for the majority of the observed association.

scholarly journals Increasing mixed-berry flavonoid intake may reduce depressive symptoms in older adults: Framingham Heart Study

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 864-864
Author(s):  
Courtney Millar ◽  
Alyssa Dufour ◽  
Marian Hannan ◽  
Shivani Sahni
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Framingham Heart Study ◽  
Randomized Clinical Trials ◽  
Epidemiological Studies ◽  
Prospective Longitudinal Study ◽  
Heart Study ◽  
Flavonoid Intake ◽  
Prospective Longitudinal ◽  
Dietary Flavonoids

Abstract Depression affects more than 250 million people worldwide. Although epidemiological studies have linked higher dietary flavonoids with depression prevention in older women, it is unknown if increasing dietary flavonoids could effectively reduce depression. Mixed berries (blueberry, blackberry, and raspberry) are a rich source of flavonoids, particularly anthocyanin, flavanol, and flavan-3-ol subclasses. Our aim was to determine the association of mixed-berry flavonoid intake with change in depressive symptoms over ~8 years in older adults from the Framingham Heart Study. This community-based prospective longitudinal study included 1,278 adults with assessments on diet (food frequency questionnaire) and depressive symptoms (Center for Epidemiologic Studies Depression, CES-D) at baseline (1998-2001) and follow-up (2005-2008). Absolute change in mixed-berry flavonoid intake (defined as sum of anthocyanin, flavanol, and flavon-3-ols, mg/day) and change in CES-D scores were calculated. Linear regression estimated beta and standard error (SE) for change in CES-D scores per 250 mg/day increase in mixed-berry flavonoids (obtained from ~3/4 cup of mixed berries), adjusting for baseline age, sex, energy-intake, current smoking, body mass index, physical activity, cardiovascular disease, and non-melanoma cancer. Mean age was 59±9 years (range: 33-81), 57% female and mean change in mixed-berry flavonoid intake was 15.0±72.8 mg/day over ~8 years. In adjusted models, each 250 mg/day increase in mixed-berry flavonoid intake was associated with a 1-point reduction in depressive symptoms (beta: -1.06, SE: 0.61, p=0.08) over ~8 years, although this was not statistically significant. These data highlight the need for randomized clinical trials of flavonoid-rich berries to target depressive symptoms in older adults.

scholarly journals Social cohesion emerging from a community-based physical activity program: A temporal network analysis

2020 ◽  
pp. 1-14
Author(s):  
Ana María Jaramillo ◽  
Felipe Montes ◽  
Olga L. Sarmiento ◽  
Ana Paola Ríos ◽  
Lisa G. Rosas ◽  
...  
Keyword(s):  
Physical Activity ◽  
Social Cohesion ◽  
Preferential Attachment ◽  
Time Windows ◽  
Clustering Coefficient ◽  
Natural Environments ◽  
Temporal Network ◽  
Community Based ◽  
Network Growth ◽  
Incremental Growth

Abstract Community-based physical activity programs, such as the Recreovía, are effective in promoting healthy behaviors in Latin America. To understand Recreovías’ challenges and scalability, we characterized its social network longitudinally while studying its participants’ social cohesion and interactions. First, we constructed the Main network of the program’s Facebook profile in 2013 to determine the main stakeholders and communities of participants. Second, we studied the Temporal network growth of the Facebook profiles of three Recreovía locations from 2008 to 2016. We implemented a Time Windows in Networks algorithm to determine observation periods and a scaling model of cities’ growth to measure social cohesion over time. Our results show physical activity instructors as the main stakeholders (20.84% nodes of the network). As emerging cohesion, we found: (1) incremental growth of Facebook users (43–272 nodes), friendships (55–2565 edges), clustering coefficient (0.19–0.21), and density (0.04–0.07); (2) no preferential attachment behavior; and (3) a social cohesion super-linear growth with 1.73 new friendships per joined user. Our results underscore the physical activity instructors’ influence and the emergent cohesion in innovation periods as a co-benefit of the program. This analysis associates the social and healthy behavior dimensions of a program occurring in natural environments under a systemic approach.

Abstract P307: Association of Psychosocial Factors With Leukocyte Telomere Length Among African Americans in the Jackson Heart Study

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Christina D Jordan
Keyword(s):  
Depressive Symptoms ◽  
African Americans ◽  
Negative Affect ◽  
Telomere Length ◽  
Psychosocial Factors ◽  
Psychosocial Stressors ◽  
Leukocyte Telomere Length ◽  
Jackson Heart Study ◽  
Heart Study ◽  
Unit Increase

Introduction: Leukocyte telomere length (LTL), a biomarker of cellular aging, is associated with human longevity. Psychosocial stressors are associated with shorter LTL. African Americans (AAs) experience greater stressor levels compared to other racial and ethnic groups. Research on associations of psychosocial factors with LTL among AAs is not well understood. Using Jackson Heart Study (JHS) data, we examined associations of psychosocial factors (negative affect and stressors) with LTL among AAs. Hypothesis: We hypothesized that psychosocial factors are inversely associated with LTL. Methods: Analysis was restricted to 2,516 JHS participants with LTL and psychosocial data between 2000-2004. Cross-sectional associations of negative affect [cynical distrust, anger-in, anger-out, depressive symptoms] and stressors [perceived stress, weekly stress inventory event (WSI-event), WSI-impact, major life event (MLE)] were examined with LTL among participants aged 21-95 years old (women=1,542; men=974). Psychosocial variables were measured by standardized questionnaires; LTL was measured by Southern blot. Summations of the four psychosocial measures were created for negative affect and stressors, with scores ranging from 4-12. We expressed each individual psychosocial measure into categories (tertiles: low, moderate, high) and in continuous standard deviation (SD) units. Using multivariable linear regression we evaluated the associations of psychosocial factors with mean differences (beta coefficient, b) in LTL adjusting for demographics (Model 1), socioeconomic status (SES) (Model 2), health behaviors, cardiovascular disease (CVD) risk factors (Model 3), and coping (Model 4). Results: High (vs low) anger-out was inversely associated with LTL in Model 1 (b = -0.043, p=0.008) and Model 2 (b = -0.0395, p=0.03), where 1-SD unit increase in anger-out was associated with shorter LTL. High (vs low) cumulative negative affect was marginally associated with insignificantly shorter LTL in Model 1 (b = -0.09, p=0.06) and Model 2 (b = -0.09, p=0.07) before transformation to SD units. There was no association between psychosocial stressors and shorter LTL in this sample. Paradoxically, high (vs low) WSI-event was positively associated with LTL (b =0.042, p=0.016), where 1-SD unit increase in WSI-event was associated with longer LTL after full adjustment. Conclusion: Depressive symptoms were associated with LTL shortening in the literature. The current study associates anger-out with shorter LTL, while WSI-event was associated with longer LTL among AAs in the JHS. Possibly, stress pathways that effect telomere length vary, where high stress can trigger LTL lengthening or shortening. Mechanisms of the paradoxical association between stress and telomere length must be further explored among AAs.

Sign in / Sign up

Export Citation Format

Share Document