Abstract P463: Objectively Measured Moderate-to-Vigorous Physical Activity is Associated With Decreased Myosteatosis in African Caribbean Adults

Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Iva Miljkovic ◽  
Allison Kuipers ◽  
Ryan Cvejkus ◽  
Victor Wheeler ◽  
Joseph Zmuda

Increased skeletal muscle fat infiltration (i.e. myosteatosis) is now recognized as a major risk factor for cardio-metabolic diseases. Therefore, a lifestyle modification that reduces myosteatosis would be of great public health importance. However, studies examining the association of relevant lifestyle factors with this ectopic fat depot are lacking, particularly in African ancestry populations who have a very high burden of cardio-metabolic diseases. The aim of this study was to examine the relation between objectively measured physical activity and sedentary behavior with computed tomography measured calf muscle attenuation among middle-aged and elderly African-Caribbeans from the population-based Tobago Health Study. Preliminary analyses were conducted among 134 women (mean age 59 yrs, mean BMI 31.6 kg/m 2 ) and 355 men (mean age 62 yrs, mean BMI 28 kg/m 2 ). Physical activity was measured using the SenseWear Pro armband worn for 4-7 days. We calculated the mean duration of waking time engaged in light physical activity (LPA), moderate to vigorous activity (MVPA), and sedentary behavior (SB) per day. Skeletal muscle attenuation (mg/cm 3 ) reflects the fat content of the muscle such that greater skeletal muscle fat infiltration is reflected by lower attenuation. Women spent less time in LPA (146 vs. 270 min/day) and MVPA (15 vs. 41 min/day), but more time in SB (789 vs. 647 min/day) than men (all p<0.0001) after adjustments for gender differences in age. Muscle attenuation was lower among women compared with men (70.5 vs. 72.7 mg/cm3; age and BMI adjusted p<0.0001). In both women and men, muscle attenuation was positively correlated with the LPA and MVPA, and inversely with time spent in SB (spearman correlation coefficients (r) ranged from 0.21 to 0.39, all p<0.006 adjusted for age). Upon additional adjustment for BMI, in both women and men, the association of muscle attenuation with MVPA remained significant (r=0.21 and r=0.18, respectively, both p<0.03), but there was no association with LPA. Percent time spent in SB was associated with muscle attenuation only among women after additional adjustment for BMI (women: -0.16, p=0.052), and we also found a significant sex interaction effect of SB on muscle attenuation (p=0.035). Our preliminary findings suggest that there is significant association between MVPA and myosteatosis among middle-aged and elderly African Caribbeans. However, SB may only be relevant for myosteatosis among women. Future analyses will be conducted in a larger sample from this cohort to confirm our findings and to test for independence from other potential confounding factors, such as diet, sleep patterns, adiposity distribution, and diabetes.

2020 ◽  
pp. 1-12
Author(s):  
Brad R. Julius ◽  
Amy M.J. O’Shea ◽  
Shelby L. Francis ◽  
Kathleen F. Janz ◽  
Helena Laroche

Purpose: The authors examined the relationship between mother and child activity. Methods: The authors compared moderate–vigorous physical activity (MVPA) and sedentary time of low-income mothers with obesity and their 6- to 12-year-old children on week (WD) and weekend (WE) days. A total of 196 mother–child pairs wore accelerometers simultaneously for a week. Mothers completed questionnaires. Spearman correlation and multivariate regression were used. Results: WE MVPA (accelerometry) was significantly correlated between mothers with children aged 6–7 (rs = .35) and daughters (rs = .27). Self-reported maternal PA time spent with one of their children was significantly correlated with the WE MVPA of all children (rs = .21) and children aged 8–10 (rs = .22) and with the WD MVPA of all children (rs = .15), children aged 8–10 (rs = .23), aged 11–12 (rs = .52), and daughters (rs = .37), and inversely correlated to the WD sedentary time of all children (rs = −.21), children aged 8–10 (rs = −.30), aged 11–12 (rs = −.34), daughters (rs = −.26), and sons (rs = −.22). In multivariate regression, significant associations were identified between reported child–mother PA time together and child MVPA and sedentary time (accelerometry). Conclusions: Mothers may influence the PA levels of their children with the strongest associations found in children aged 6–7 and daughters. Mother–child coparticipation in PA may lead to increased child MVPA and decreased sedentary behavior.


2010 ◽  
Vol 7 (4) ◽  
pp. 475-483 ◽  
Author(s):  
Karla E. Foster ◽  
Timothy K. Behrens ◽  
Abigail L. Jager ◽  
David A. Dzewaltowski

Background:This study evaluated the effect of elimination and nonelimination games on objectively measured physical activity and psychosocial responses in children.Methods:A total of 29 children in grades 4 to 6 (65.5% male; 10.5 ± 1.0 years old) wore an accelerometer while participating in 2 elimination and 2 nonelimination games. Activity counts were collected using a 30-second epoch and converted to METs to determine minutes spent in sedentary behavior and light, moderate, vigorous, and moderate-to-vigorous physical activity. Self-efficacy, enjoyment, and peer-victimization were assessed on 4 occasions (before and after 2 elimination and 2 nonelimination games).Results:Overall, girls spent more time in sedentary behavior compared with boys. Children engaged in significantly more moderate-to-vigorous physical activity during nonelimination games compared with elimination games. Furthermore, children significantly increased self-efficacy after playing both game sessions. A significant interaction between type of game and time of measurement in the prediction of enjoyment showed that enjoyment modestly increased after elimination games and slightly decreased after nonelimination games. There were no differences in peer-victimization.Conclusion:This study provides preliminary evidence that nonelimination games provide more moderate-to-vigorous physical activity compared with elimination games, but elimination games may be more enjoyable.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 168-169
Author(s):  
Steve Nguyen ◽  
John Bellettiere ◽  
Michael LaMonte ◽  
Carolyn Crandall ◽  
Andrea LaCroix

Abstract Women aged 65 and older experience nearly three-fourths of the 2 million osteoporotic fractures annually in the US, yet whether accelerometer-measured volumes and intensities of physical activity and sedentary behavior (SB) are associated with reduced fracture risk is understudied. We investigated associations of accelerometer-measured light physical activity (LPA), moderate-to-vigorous physical activity (MVPA), sedentary time (ST), and mean sedentary bout duration (MBD) with incident clinical fractures (hip, vertebral, pelvis, lower leg, upper arm, forearm, and wrist) in the WHI OPACH cohort. Participants (N=6248; mean±SD age=78.6±6.7; 34% Black, 17% Hispanic) without prior hip fracture wore the ActiGraph GT3X+ for 7 days between May 2012-April 2014 and were followed through March 2020 for incident clinical fracture (N=711). Cox models estimated hazard ratios (HR) and 95% confidence intervals (CI), adjusting for age, race-ethnicity, education, alcohol, smoking, height, weight, falls history, RAND-36 physical function, diabetes, thiazide use, prescription osteoporotic therapy, and age at menopause. The HR(95% CI) across MVPA quartiles was 1.00(reference), 1.15(0.93-1.41), 0.90(0.72-1.13), and 0.79(0.61-1.02); p-trend=0.01. The HR(95% CI) for a one-interquartile range increment in MVPA (42 minutes/day) was 0.86(0.76-0.97). Associations were modified by prescription osteoporotic therapy [no: HR=0.77(0.66-0.89), yes: HR=1.03(0.85-1.25); p-interaction=0.01] and varied in magnitude by age[&lt;80: HR=0.78(0.64-0.96), ≥80: HR=0.92(0.79-1.07); p-interaction=0.09], BMI [&lt;30 kg/m2: HR=0.85(0.75-0.97), ≥30 kg/m2: HR=0.90(0.67-1.19); p-interaction=0.08], and race-ethnicity [Black: HR =0.63(0.44-0.89), Hispanic: HR =0.78(0.56-1.09), White: HR =0.92(0.80-1.06); p-interaction=0.16]. LPA, ST, or MBD were not associated with incident fractures. These data suggest that MVPA may reduce and not increase fracture risk and that LPA and SB do not increase fracture risk.


Author(s):  
Maria M. Ekblom ◽  
Örjan B. Ekblom ◽  
Mats Börjesson ◽  
Göran Bergström ◽  
Christina Jern ◽  
...  

High aerobic fitness, more moderate to vigorous physical activity (MVPA) and less sedentary behavior (SED) have all been suggested to promote cognitive functions, but it is unclear whether they are independent predictors of specific cognitive domains. This study aimed to investigate to what extent aerobic fitness MVPA and SED are independently associated with cognitive performance among middle-aged Swedish adults. We acquired device-based measures of aerobic fitness, cognitive performance and percent daily time spent in MVPA and SED in Swedish adults (n = 216; 54–66 years old). Aerobic fitness was associated with better performance at one out of two tests of speed/attention and one out of four tests of executive attention, and with worse performance at one of seven tests of memory. Increasing %MVPA was associated with better performance at one out of seven tests of memory and two out of three tests of verbal ability, whereas increasing %SED was associated with better performance at all four tests of executive attention and four out of seven tests of memory. These findings suggest that aerobic fitness, %MVPA and %SED are partly independent correlates of cognitive performance. To fully understand the association between SED and performance at several tests of cognitive function, future investigations might attempt to investigate intellectually engaging SED (such as reading books) separately from mentally undemanding SED (such as watching TV).


2021 ◽  
Author(s):  
Victoria Costello ◽  
Guillaume Chevance ◽  
David Wing ◽  
Shadia J, Assi ◽  
Sydney Sharp ◽  
...  

BACKGROUND The COVID-19 pandemic impacted multiple aspects of daily living, including behaviors associated with occupation, transportation, and health. It is unclear how these changes to daily living impacted physical activity and sedentary behavior. OBJECTIVE To examine the impact of the COVID-19 mitigation strategies on physical activity and sedentary behavior among young adults enrolled in an ongoing weight loss trial using longitudinal data acquired from wrist-worn activity monitors over the course of 1 year in San Diego, CA. METHODS Date were collected in 315 participants between 11/01/2019 and 10/30/2020 using the Fitbit Charge 3. After strict filtering for valid consistent wear (more than 10 hours per day for 250+ days), data from 97 participants were analyzed to detect multiple structural changes in time series of physical activity and sedentary behavior. RESULTS After initiation of the shelter-in-place order in CA on 03/19/2021, there were significant decreases in step counts (-2872 steps per day, 95% CI [-2734; -3010]), light physical activity (-41·9 minutes, 95% CI [39·5, 44·3]), and moderate-to-vigorous physical activity (-12·2 minutes, 95% CI [10·6, 13·8]), as well as significant increases in sedentary behavior (+52·8 minutes, 95% CI [47.0, 58.5]). Decreases were greater than expected declines observed during winter holidays, and as of 10/30/2020, they had not returned to levels observed prior to shelter-in-place orders. CONCLUSIONS In young adults, physical activity decreased and sedentary behavior increased concurrent with COVID-19 mitigation strategies. Health conditions associated with sedentary lifestyle may be additional unintended costs of the COVID-19 pandemic. CLINICALTRIAL NIH 5R01HL136769-03)


2020 ◽  
Vol 12 (15) ◽  
pp. 5890 ◽  
Author(s):  
Borja Sañudo ◽  
Curtis Fennell ◽  
Antonio J. Sánchez-Oliver

This study assessed the effects of COVID-19 home confinement on physical activity, sedentary behavior, smartphone use, and sleep patterns. Data was collected in a sample of 20 young adults (mean age ± SD: 22.6 ± 3.4 years; 55% males) over seven days pre- and during the COVID-19 lockdown. Objective and subjective physical activity (Accelerometer and the International Physical Activity Questionnaire (IPAQ), respectively), the number of hours sitting (IPAQ), objectively-measured smartphone use (smartphone screen time applications), and objective and subjective sleep (accelerometer and the Pittsburgh Sleep Quality Index, respectively) were assessed. Results revealed significantly greater walking time and mean steps (p < 0.001, d = 1.223 to 1.605), and moderate and vigorous physical activity (p < 0.05, d = 0.568 to 0.616), in the pre- compared with the during-COVID-19 lockdown phase. Additionally, smartphone use (p = 0.009, d = 0.654), sitting time (p = 0.002, d = 1.120), and total sleep (p < 0.004, d = 0.666) were significantly greater in the during- compared with the pre-COVID-19 lockdown phase. Multiple regressions analyses showed associations between physical activity and sedentary behavior and sleep quality. The number of hours sitting per day and moderate-to-vigorous physical activity significantly predicted deep sleep (adj.R2 = 0.46). In conclusion, this study revealed that during the COVID-19 outbreak, behaviors changed, with participants spending less time engaging in physical activity, sitting more, spending more time using the smartphone, and sleeping more hours. These findings may be of importance to make recommendations, including lifestyle modifications during this time.


Author(s):  
Emerald G. Heiland ◽  
Örjan Ekblom ◽  
Emil Bojsen-Møller ◽  
Lisa-Marie Larisch ◽  
Victoria Blom ◽  
...  

The bi-directional, day-to-day associations between daytime physical activity and sedentary behavior, and nocturnal sleep, in office workers are unknown. This study investigated these associations and whether they varied by weekday or weekend day. Among 324 Swedish office workers (mean age 42.4 years; 33.3% men), moderate-to-vigorous physical activity (MVPA), and sedentary behaviors and sleep (total sleep time (TST) and sleep efficiency (SE)) were ascertained by using accelerometers (Actigraph GT3X) over 8 days. Multilevel linear mixed models were used to assess the bi-directional, day-to-day, within-person associations. Additional analyses stratified by weekend/weekday were performed. On average, participants spent 6% (57 min) of their day in MVPA and 59% (9.5 h) sedentary, and during the night, TST was 7 hours, and SE was 91%. More daytime sedentary behavior was associated with less TST that night, and reciprocally, more TST at night was associated with less sedentary behavior on the following weekday. Greater TST during the night was also associated with less MVPA the next day, only on weekdays. However, daytime MVPA was not associated with TST that night. Higher nighttime SE was associated with greater time spent sedentary and in MVPA on the following day, regardless if weekday or weekend day. Sleep may be more crucial for being physically active the following day than vice versa, especially on weekdays. Nevertheless, sedentary behavior’s relation with sleep time may be bi-directional. Office workers may struggle with balancing sleep and physical activity time.


2020 ◽  
Vol 29 (1) ◽  
pp. 34-39
Author(s):  
Si Chen ◽  
Tao Chen ◽  
Shuzo Kumagai ◽  
Hyuntae Park

PURPOSE: This review aimed to evaluate the relationship between objectively measured physical activity and sedentary behavior and frailty in community-dwelling older adults.METHODS: An electronic search was undertaken using the MEDLINE® databases from January 1st 2010 to December 31st 2019. Titles, abstracts, and full texts of the studies identified by the search were scrutinized by the author to determine eligibility for an inclusion in this review.RESULTS: The search identified 87 relevant articles resulted, of which eight studies from four cohorts met the inclusion requirements. Almost all the studies reported a significantly negative association between moderate-to-vigorous physical activity (MVPA) and frailty, while only one was a longitudinal study. Significant associations between sedentary time (ST) and higher severity of frailty were observed, however, the findings of associations of sedentary bouts were mixed.IMPLICATION: Higher amounts of ST and lower amounts of MVPA were associated with a higher prevalence of frailty or worse frailty levels. Replacing ST with MVPA may offset the detrimental consequences of ST on frailty. More longitudinal studies and quantitative researches are needed to investigate the association of MVPA and ST bouts with frailty.


2020 ◽  
Vol 17 (3) ◽  
pp. 343-348
Author(s):  
Sheri J. Hartman ◽  
Dori Pekmezi ◽  
Shira I. Dunsiger ◽  
Bess H. Marcus

Background: Latinas have high rates of sedentary behavior and related health disparities, but it is unknown if interventions to increase physical activity will also reduce sedentary time. The current study examined changes in objectively measured sedentary time among Latinas in a randomized controlled trial of a physical activity intervention. Methods: Spanish-speaking Latinas (N = 202) were randomized to an exercise or wellness group and wore an accelerometer at baseline, 6 months, and 12 months. Results: Participants were sedentary on an average of 8.86 hours per day (SD = 2.60) at baseline. The intervention group had significantly greater increases in sedentary time compared with the control group, with the intervention group engaging in 146 more minutes per week of sedentary time at 6 months and 254 minutes per week of sedentary time at 12 months than the control group (P = .02). The intervention effect on sedentary behavior remained after controlling for moderate to vigorous physical activity. Additionally, time spent in moderate to vigorous physical activity was positively associated with more sedentary time (P = .04). Conclusion: An intervention to increase moderate to vigorous physical activity resulted in greater sedentary time, raising concerns regarding compensation and highlighting the need for interventions to address both physical activity and sedentary behavior to improve public health.


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