Abstract 075: Differences In Body Composition At Baseline And In Response To Exercise Training By Metabolic Health And Weight Status

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Alexis Jones ◽  
Jacob L Barber ◽  
James S Skinner ◽  
Claude Bouchard ◽  
Mark A Sarzynski
Keyword(s):  
Body Composition ◽  
Exercise Training ◽  
Visceral Fat ◽  
Weight Status ◽  
Normal Weight ◽  
Metabolic Health ◽  
Fat Free Mass ◽  
Obese Adults ◽  
Change Models ◽  
Metabolically Healthy

Background: Body composition is known to differ across metabolic health and weight phenotypes. Regular exercise improves body composition, yet little is known about differences in exercise response across metabolic health and weight phenotypes. Methods: Normal weight (n=376) and overweight/obese (OWOB) adults (n=456) from the HERITAGE Family Study (56% female, 38% Black) completed a 20-week endurance training program. Four groups based on baseline BMI and metabolic risk were created: metabolically healthy normal weight, MHNW; metabolically unhealthy normal weight, MUNW; metabolically healthy OWOB, MHO; and metabolically unhealthy OWOB, MUO. Unhealthy was defined as having ≥2 metabolic syndrome components. General linear models tested for differences in baseline and change in measures of body composition (fat mass [FM], fat-free mass [FFM], % body fat [%BF], visceral fat) after adjusting for age, sex, and ethnicity (and baseline value in change models). Results: Table 1 shows adjusted mean baseline and change in body composition values by group. Baseline body composition tended to track with weight status, with NW adults having lower FM, %BF, and visceral fat compared to obese adults (p<0.05), regardless of metabolic health. However, the MHO group had lower baseline values of these traits compared to MUO (p<0.05). Body composition measures significantly improved with exercise training in all groups, however, the magnitude of change differed between groups. For example, both NW groups had larger decreases in %BF compared to the obese groups, with MUNW showing the largest decrease. Conversely, MHNW showed the largest decrease in visceral fat, which was greater than both obese groups, but change in visceral fat was similar between MHO and MUNW. Conclusions: Normal weight adults tended to have better body composition profiles at baseline and larger improvements with exercise compared to obese adults, regardless of metabolic health. Within weight groups, body composition improved regardless of metabolic health status.

scholarly journals Systemic Inflammation Characterizes Lack of Metabolic Health in Nonobese HIV-Infected Men

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Ana N. Monczor ◽  
Xiuhong Li ◽  
Frank J. Palella ◽  
Kristine M. Erlandson ◽  
Dorothy Wiley ◽  
...  
Keyword(s):  
Systemic Inflammation ◽  
Visceral Fat ◽  
Subcutaneous Fat ◽  
Normal Weight ◽  
Metabolic Health ◽  
Model Assessment ◽  
Cross Sectional ◽  
Inflammatory Biomarker ◽  
Hiv Serostatus ◽  
Metabolically Healthy

Background. Increasing body mass index (BMI) is generally associated with loss of metabolic health, although some obese individuals remain metabolically healthy. Among nonobese men, HIV infection has been associated with a lower prevalence of metabolic health. Methods. We conducted a cross-sectional analysis of 470 HIV-infected and 368 HIV-uninfected men enrolled in the Multicenter AIDS Cohort Study Cardiovascular substudy. Circulating biomarker levels were compared by BMI category and by HIV serostatus. Poisson regression with robust variance determined associations between metabolic health and circulating inflammatory biomarker levels after adjusting for factors previously associated with metabolic health. Results. HIV-infected men were younger and less likely to be obese. Among HIV-infected, normal weight metabolically healthy men (compared to unhealthy) had significantly lower circulating levels of interleukin- (IL-) 6, soluble tumor necrosis factor receptors (sTNFR) I and II, and homeostatic model assessment of insulin resistance (HOMA-IR), higher adiponectin, less visceral fat, and more subcutaneous fat. Among HIV-uninfected normal weight men and obese men (regardless of HIV serostatus), metabolic health was associated only with higher levels of adiponectin, less visceral fat, and lower HOMA-IR values. In multivariate analyses restricted to HIV-infected men, lower hs-CRP, sTNFRI, sTNFRII, and HOMA-IR and higher adiponectin levels were associated with metabolic health. Additional adjustment for visceral adiposity did not alter results. Conclusions. Among HIV-infected normal weight men, metabolic health was associated with less systemic inflammation, a relationship that, among normal weight men, was unique to HIV+ men and did not exist among obese men of either HIV serostatus.

scholarly journals Influence of Body Composition on Physical Fitness in Adolescents

Medicina ◽  
2020 ◽  
Vol 56 (7) ◽  
pp. 328
Author(s):  
María Mendoza-Muñoz ◽  
José Carmelo Adsuar ◽  
Jorge Pérez-Gómez ◽  
Laura Muñoz-Bermejo ◽  
Miguel Ángel Garcia-Gordillo ◽  
...  
Keyword(s):  
Body Composition ◽  
Physical Fitness ◽  
Weight Status ◽  
Handgrip Strength ◽  
Normal Weight ◽  
Fat Free Mass ◽  
Regression Equations ◽  
Obese Adolescents ◽  
Fitness Test ◽  
Fitness Tests

Background and objectives: Childhood obesity is one of the main public health issues facing advanced societies. The Spanish population presents 28.6% overweight or obese adolescents, and Extremadura, 22.3%. Physical fitness is considered one of the most important health markers and a common predictor of morbidity and mortality caused by cardiovascular diseases. Thus, fitness tests are needed for health monitoring, especially in overweight and obese adolescents. Therefore, this study aimed to explore the relationship between body composition and physical fitness in adolescents and to analyse if there are differences in physical condition and body composition between the sexes, as well as to compare the different body mass index (BMI) categories to each other. This project also tried to find regression equations to predict the physical fitness test results. Materials and Methods: A total of 225 adolescents were recruited. Weight status was classified according to WHO 2007 standards. Body composition variables (i.e., BMI, fat mass (FM), FM percentage (FM%), and fat-free mass (FFM)) and physical fitness (standing long jump (SLJ), speed–agility (SA), cardiorespiratory fitness (CF), and handgrip strength (HS)) were assessed. Results: Significant differences were found between the sexes in body composition (FM%, FM, and FFM) and physical fitness (SLJ, SA, CF, and HS) (p < 0.001) in favour of males. Significant differences were also found in speed (p = 0.002), CF (p < 0.001), and SLJ (p = 0.004) in favour of normal-weight adolescents compared to overweight and obese adolescents. Contrarily, the outcomes revealed a significantly greater HS (p = 0.014) in favour of overweight and obese participants compared to normal-weight adolescents. Moreover, the results showed that CF and SLJ correlated inversely with BMI, FM%, and total FM. There was also a direct relationship between SA and FM percentage, as well as between HS and FFM. Finally, four fitness test predictive models are proposed based on body composition, age, sex, and BMI. Conclusions: Overweight and obese adolescents have lower levels of physical fitness than their normal-weight peers, regardless of their sex. Normal-ranged body composition values are related to a greater physical fitness in adolescents. Furthermore, this study presents several equations that can help to predict the performance of different fitness tests in adolescents.

scholarly journals Physical fitness in preschoolers according to body composition

2019 ◽  
Vol 24 ◽  
pp. 51-59
Author(s):  
Eva-Maria Riso ◽  
Lisette Toplaan ◽  
Piret Viira ◽  
Sille Vaiksaar ◽  
Jaak Jürimäe
Keyword(s):  
Body Mass Index ◽  
Body Composition ◽  
Physical Fitness ◽  
Body Mass ◽  
Weight Status ◽  
Handgrip Strength ◽  
Weight Bearing ◽  
Normal Weight ◽  
Fat Free Mass ◽  
Fitness Tests

The objective of this study was to investigate physical fitness of preschoolaged children just before entering school according to their body mass index, and to examine possible associations of body mass index, fat mass and fat-free mass with physical fitness in preschool-aged children. Two hundred and fifty-six preschoolers aged 6 to 7 years participated in the study. Physical fitness was assessed using PREFIT test battery and body composition was estimated using four skinfold thickness parameters. Overweight children had lower cardiorespiratory fitness and lower results in all weight-bearing fitness tests, and better handgrip strength test result in comparison with normal-weight children. Significant associations were found between body composition indices and the results of physical fitness tests. Higher BMI associated negatively with weight-bearing physical fitness tests. The results of the research indicate that weight-status and body composition have significant effect on physical fitness in 6–7 years old preschoolers.

scholarly journals Differences in body composition between metabolically healthy and unhealthy midlife women with respect to obesity status

2021 ◽  
Vol 84 (1) ◽  
pp. 59-71
Author(s):  
Lenka Vorobeľová ◽  
Darina Falbová ◽  
Daniela Siváková
Keyword(s):  
Body Composition ◽  
Smoking Status ◽  
Menopausal Status ◽  
Sport Activity ◽  
Density Lipoprotein ◽  
Logistic Models ◽  
Normal Weight ◽  
Metabolic Health ◽  
Midlife Women ◽  
Metabolically Healthy

Abstract Body composition (BC) characteristics across metabolic health-by-body mass index categories were examined. Metabolic health (MH) was defined by five biomarkers: waist circumference, blood pressure, levels of triglycerides, high density lipoprotein cholesterol, and fasting glucose. Potential differences in BC characteristics between metabolically healthy obese (MH-O) and metabolically unhealthy obese (MUH-O) women, and between MH normal weight (MH-NW) and MUH normal weight (MUH-NW) women were explored in 276 Slovak midlife women (39-65 years). Body composition parameters were measured with bioimpedance analyzer (BIA 101, Akern, S. r. l.). A simple comparison of the BC data between the subgroups showed significant differences in resistance (Rz, ohm) (p=0.035), muscle mass (MM, kg) (p=0.044), and total body water (TBW, kg) (p=0.047) between MH-O and MUH-O women. However, we did not observe any significant differences in BC characteristics between MH-NW and MUHNW. Specific logistic regression models were used to determine differences in BC characteristics between various obesity phenotypes, with controlling for age, menopausal status, smoking status and sport activity. Our results indicated that increasing age and decreasing Rz were statistically significantly associated with an increased likelihood of exhibiting MUH-O (p=0.031 for age; p=0.032 for Rz). Moreover, other logistic models which included age, menopausal status, biochemical variables and life style factors such as covariates, showed that increasing alanine aminotransferase (ALT) and uric acid (UA) were statistically significantly associated with an increased likelihood of exhibiting MUH-O (p=0.023 for ALT, p=0.010 for UA). In conclusion, MUH-O and MH-O cardiometabolic profiles are characterized by differences in the value of resistance and plasma levels of ALT and UA.

scholarly journals Awareness and knowledge about weight status and management: results from the 1 d sensitization campaign ‘Obesity Day’ in northern Italy

2011 ◽  
Vol 14 (10) ◽  
pp. 1813-1822 ◽  
Author(s):  
Michela Barichella ◽  
Alexis E Malavazos ◽  
Giuseppe Fatati ◽  
Emanuele Cereda
Keyword(s):  
Physical Activity ◽  
Weight Management ◽  
Health Care Professionals ◽  
Weight Control ◽  
Weight Status ◽  
Normal Weight ◽  
Cross Sectional Survey ◽  
Obese Adults ◽  
Cross Sectional

AbstractObjectiveTo evaluate the awareness and knowledge about weight status and its management.DesignA 1 d cross-sectional survey. Basic anthropometric assessments (weight, height, BMI and waist circumference) and a self-administered questionnaire were considered.SettingNineteen Clinical Nutrition or Endocrinology and Metabolic Disorders Units or Dietetics Services in the Italian region of Lombardy.SubjectsAll adults attending the ‘Obesity Day’ initiative.ResultsA total of 914 participants (605 female and 309 male) were recruited. Although most of the participants (83·5 %) considered obesity to be a disease, 38·5 % were likely to misperceive their weight status. In particular, 38·8 % of normal-weight adults believed themselves to be overweight, whereas 71·1 % and 37·5 % of classes I and II/III obese adults classified themselves as being overweight and mildly obese, respectively. However, most of the overweight (90·2 %), mildly (96·8 %) and moderately/severely obese adults (99·1 %) recognized the need to lose weight. In all, 37·8 % of the sample underestimated the role of physical activity in weight management. Interestingly, only 17·2 % of dieters (previous or current) declared being advised by their doctor to lose weight. Multivariate models revealed that higher age, low education and higher BMI were important determinants of poor weight control and management. In addition, previous dieting appeared not to provide better knowledge, whereas the role of physical activity was recognized mainly by those practising it.ConclusionsThe present study suggests that in Italy knowledge about weight management should be improved not only in the general population but also among health-care professionals. To confirm this finding, there is now the rationale for a nationally representative survey. New educational programmes can be designed on the basis of the information collected.

scholarly journals Body composition in childhood: effects of normal growth and disease

2003 ◽  
Vol 62 (2) ◽  
pp. 521-528 ◽  
Author(s):  
J. C. K. Wells
Keyword(s):  
Body Composition ◽  
Childhood Obesity ◽  
Fat Mass ◽  
Lean Mass ◽  
Normal Weight ◽  
Fat Free Mass ◽  
General Interest ◽  
Childhood And Adolescence ◽  
Adult Disease ◽  
Increased Risk

Body composition in children is of increasing interest within the contexts of childhood obesity, clinical management of patients and nutritional programming as a pathway to adult disease. Energy imbalance appears to be common in many disease states; however, body composition is not routinely measured in patients. Traditionally, clinical interest has focused on growth or nutritional status, whereas more recent studies have quantified fat mass and lean mass. The human body changes in proportions and chemical composition during childhood and adolescence. Most of the weight gain comprises lean mass rather than fat. In general, interest has focused on percentage fat, and less attention has been paid to the way in which lean mass varies within and between individuals. In the general population secular trends in BMI have been widely reported, indicating increasing levels of childhood obesity, which have been linked to reduced physical activity. However, lower activity levels may potentially lead not only to increased fatness, but also to reduced lean mass. This issue merits further investigation. Diseases have multiple effects on body composition and may influence fat-free mass and/or fat mass. In some diseases both components change in the same direction, whereas in other diseases, the changes are contradictory and may be concealed by relatively normal weight. Improved techniques are required for clinical evaluations. Both higher fatness and reduced lean mass may represent pathways to an increased risk of adult disease.

Testosterone and exercise: Effects on fitness, body composition and strength in middle-to-older aged men with low-normal serum testosterone levels.

2021 ◽  
Author(s):  
Lauren C. Chasland ◽  
Bu B Yeap ◽  
Andrew J. Maiorana ◽  
Yi X Chan ◽  
Barbara A Maslen ◽  
...  
Keyword(s):  
Body Composition ◽  
Exercise Training ◽  
Aerobic Capacity ◽  
Lean Mass ◽  
Visceral Fat ◽  
Serum Testosterone ◽  
Normal Serum ◽  
Testosterone Treatment ◽  
Leg Strength ◽  
Therapeutic Doses

As men age, serum testosterone (T) concentrations decrease, as do fitness, strength and lean mass. Whether testosterone treatment confers additive benefit to reverse these changes when combined with exercise training in middle-to-older aged men remains unclear. We assessed the effects of T treatment and exercise, alone and in combination, on aerobic capacity (VO2peak), body composition and muscular strength in men 50-70yrs, waist circumference ≥95cm and low-normal serum T (6-14nmol·L−1). Participants (n=80) were randomised to AndroForte5® (Testosterone 5.0%w/v, 100mg/2mL) cream (T), or matching placebo (P), applied transdermally daily, and supervised centre-based exercise (Ex) or no additional exercise (NEx), for 12-weeks. Exercise increased VO2peak and strength vs non-exercise (VO2peak: T+Ex:+2.5, P+Ex:+3.2mL·kg−1·min−1, P<0.001; leg press: T+Ex:+31, P+Ex:+24kg, P=0.006). T treatment did not affect VO2peak or strength. Exercise decreased total (T+Ex:-1.7, P+Ex-2.3kg, P<0.001) and visceral fat (T+Ex:-0.1, P+Ex:-0.3kg, P=0.003), and increased total (T+Ex:+1.4, P+Ex:+0.7kg, P=0.008) and arm lean mass (T+Ex:+0.5, P+Ex:+0.3kg, P=0.024). T treatment did not affect total or visceral fat, but increased total (T+Ex:+1.4, T+NEx:+0.7kg, P=0.015), leg (T+Ex:+0.3, T+NEx:+0.2kg, P=0.024) and arm lean mass (T+Ex:+0.5, T+NEx:+0.2kg, P=0.046). T+Ex increased arm lean mass (T+Ex:+0.5kg vs P+NEx:-0.0kg, P=0.001) and leg strength (T+Ex:+31 vs P+NEx:+12kg, P=0.032) compared to P+NEx, with no other additive effects. Exercise training was more effective than T treatment in increasing aerobic capacity and decreasing total and visceral fat mass. T treatment at therapeutic doses increased lean mass but conferred limited additional benefit when combined with exercise. Exercise should be evaluated as an anti-ageing intervention in preference to testosterone treatment in men.

scholarly journals "Pause-2-Play": a pilot schoolbased obesity prevention program

2010 ◽  
Vol 10 (3) ◽  
pp. 303-311
Author(s):  
Gregory Killough ◽  
Danielle Battram ◽  
Joanne Kurtz ◽  
Gillian Mandich ◽  
Laura Francis ◽  
...  
Keyword(s):  
Body Composition ◽  
Obesity Prevention ◽  
Prevention Program ◽  
Healthy Lifestyle ◽  
Normal Weight ◽  
Fat Free Mass ◽  
Overweight Children ◽  
School Students ◽  
Fitness Level ◽  
Obesity Prevention Program

OBJECTIVES: "Pause-2-Play" is an obesity prevention program targeting screen-related sedentary behaviours and increasing physical activity among elementary school students. The program consisted of a Behavioural Modification Curriculum and a Health Promoting Afterschool Program. This pilot study reports program feasibility, practicability, and impact. METHODS: the 12-week pilot program was implemented with 32 grade five and six students. Program feasibility and practicability were assessed using a qualitative approach. Intervention effects were assessed by comparing pre-post changes in BMI, body composition, fitness scores, screen time, and cognitive variables related to screening viewing behaviours. RESULTS: "Pause-2-Play" was perceived as a useful, fun program with numerous benefits including: children trying new snacks, feeling fitter and better about one's own body shape, and becoming more aware of a healthy lifestyle. The intervention resulted in a statistically significant reduction in percent body fat and an increase in fat-free mass index in overweight children; a decrease in waist circumference and an increase in fat-free mass index were observed in normal weight children. The intervention also statistically improved fitness scores in both normal weight and overweight children. CONCLUSIONS: "Pause-2-Play" was feasible, practical, and favourably changed body composition and fitness level.

Accelerometer Response to Physical Activity Intensity in Normal-Weight Versus Overweight African American Children

2011 ◽  
Vol 8 (5) ◽  
pp. 682-692 ◽  
Author(s):  
Daniel Arvidsson ◽  
Mark Fitch ◽  
Mark L. Hudes ◽  
Catrine Tudor-Locke ◽  
Sharon E. Fleming
Keyword(s):  
Physical Activity ◽  
African American ◽  
Weight Status ◽  
Normal Weight ◽  
Fat Free Mass ◽  
African American Children ◽  
Overweight Children ◽  
Physical Activity Intensity ◽  
Activity Intensity ◽  
American Children

Background:Different movement efficiency in overweight children may affect accelerometer output data. The purpose was to investigate the ability of accelerometers to assess physical activity intensity and number of steps in normal-weight compared with overweight children.Methods:Eleven normal-weight and 14 overweight African American children walked at 2, 4, 5, and 6 km/h on a treadmill wearing Lifecorder, ActiGraph, RT3, and Biotrainer. Oxygen uptake was measured and steps manually counted. Fat free mass (FFM) was assessed from bioelectrical impedance analysis. Accelerometer counts and the individual linear regression lines of accelerometer counts versus VO2/FFM were evaluated, together with steps recorded by Lifecorder and Actigraph.Results:Correlations between accelerometer counts and VO2/FFM for all monitors were r ≥ .95 (P < .01). The accelerometer counts and their relationship to VO2/FFM did not generally differ significantly by body weight status. Lifecorder and Actigraph underestimated steps at 4, 5, and 6 km/h by less than 9%, but the error was up to −95% at 2 km/h.Conclusions:All 4 accelerometers show high ability to assess physical activity intensity, and can be used to compare physical activity between normal-weight and overweight children. The Lifecorder and the ActiGraph showed high accuracy in assessing steps, providing speed of movement exceeded 2 km/h.

scholarly journals Effect of very low-calorie ketogenic diet in combination with omega-3 on inflammation, satiety hormones, body composition, and metabolic markers. A pilot study in class I obese subjects

Endocrine ◽  
2021 ◽  
Author(s):  
Mariangela Rondanelli ◽  
Simone Perna ◽  
Zahra Ilyas ◽  
Gabriella Peroni ◽  
Philip Bazire ◽  
...  
Keyword(s):  
Body Composition ◽  
Visceral Fat ◽  
Mean Difference ◽  
Fat Free Mass ◽  
Class I ◽  
Omega 3 ◽  
Open Label ◽  
Metabolic Markers ◽  
High Loss ◽  
Class I Obesity

Abstract Purpose This study aims to evaluate the effects of a VLCKD combined with omega-3 supplementation (VLCKD diet only lasted for some weeks, and it was followed by a non-ketogenic LCD for the rest of the study period) on body composition, visceral fat, satiety hormones, inflammatory and metabolic markers. Methods It has been performed a pilot open label study lasted 90 days, in a cohort of 12 women with class I obesity aged 18 to 65 years. Data on body composition (evaluated by Dual X-Ray Absorptiometry—DXA), visceral fat, satiety hormones, inflammatory and metabolic markers were recorded. Results This study showed a body weight reduction mean difference over time of −13.7 kg and the waist circumference mean difference decrease of −13.3 cm. Also, the fat mass (FM) decreased—9.1 kg and visceral adipose tissue (VAT)—0.41 kg. No effects on fat-free mass (FFM) have been reported. Improvements were observed in the satiety hormones, with increased ghrelin and decreased leptin, and also in the metabolic profiles. Conclusions A VLCKD combined with omega-3 supplementation appears to be an effective strategy for promoting an high loss of FM with preservation of FFM in patients with class I obesity.

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