scholarly journals Diagnosis and Inconsistency in the Axiochus

2021 ◽  
pp. 1-18
Author(s):  
Albert Joosse
Keyword(s):  
Critical Thinking ◽  
Therapeutic Strategy ◽  
Fear Of Death ◽  
Different Levels

Abstract The Socrates of the dialogue Axiochus seems to advance incompatible arguments in his attempt to cure Axiochus of his fear of death. Is this incompatibility a foreseen and accepted consequence of the author’s therapeutic strategy? This paper argues that it is rather an intended and functional inconsistency: it serves to stimulate critical thinking in order to anchor philosophical conviction more deeply in the reader’s soul. The paper musters support for this reading by drawing attention to the different levels of inconsistency in the dialogue; the multiple ways in which the text thematizes inconsistency; the importance of exercising judgement in the text; and the motivating concern of superficial persuasion.

scholarly journals Critical Thinking in Health Sciences and How It Pertains to Sonography Education: A Review of the Literature

2020 ◽  
Vol 36 (3) ◽  
pp. 244-250
Author(s):  
Brandy Weidman ◽  
Helen Salisbury
Keyword(s):  
Critical Thinking ◽  
Professional Practice ◽  
Cognitive Abilities ◽  
Thinking Skills ◽  
Health Sciences ◽  
Critical Thinking Skills ◽  
Review Of The Literature ◽  
Reasoning Test ◽  
Health Sciences Students ◽  
Different Levels

Objective: Critical thinking is an important skill that sonographers must develop beginning in educational programs and into professional practice. Critical thinking requires students to reflect on information, use judgment skills, and engage in higher levels of thinking, including analysis, interpretation, inference, evaluation, and explanation, to formulate reliable decisions. Methods: Current research related to critical thinking has focused on medicine, nursing, physical therapy, pharmacy, and dental programs, but there has been no description of assessing sonography students. The Dreyfus model has been used as a framework to describe acquired skills that reflects students’ progress from novice to expert clinicians. This model illustrates specific cognitive abilities that students develop as they advance in education. Results: This review of the literature describes critical thinking skills coupled with a framework to understand different levels of cognitive thinking, as well as how it can be assessed. Conclusion: To understand differences between undergraduate sonography students and experts, the Dreyfus model is an excellent model to recognize progression. It can be used with the Health Sciences Reasoning Test, which is a nationally recognized critical thinking examination that can ascertain different levels of health sciences students’ critical thinking skills.

scholarly journals A Peptide Nucleic Acid (PNA) Masking the miR-145-5p Binding Site of the 3′UTR of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) mRNA Enhances CFTR Expression in Calu-3 Cells

Molecules ◽  
2020 ◽  
Vol 25 (7) ◽  
pp. 1677 ◽  
Author(s):  
Shaiq Sultan ◽  
Andrea Rozzi ◽  
Jessica Gasparello ◽  
Alex Manicardi ◽  
Roberto Corradini ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Binding Site ◽  
Peptide Nucleic Acid ◽  
Therapeutic Strategy ◽  
Transmembrane Conductance Regulator ◽  
Transmembrane Conductance ◽  
Treatment Protocols ◽  
Cftr Protein ◽  
Cystic Fibrosis Transmembrane ◽  
Different Levels

Peptide nucleic acids (PNAs) have been demonstrated to be very useful tools for gene regulation at different levels and with different mechanisms of action. In the last few years the use of PNAs for targeting microRNAs (anti-miRNA PNAs) has provided impressive advancements. In particular, targeting of microRNAs involved in the repression of the expression of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which is defective in cystic fibrosis (CF), is a key step in the development of new types of treatment protocols. In addition to the anti-miRNA therapeutic strategy, inhibition of miRNA functions can be reached by masking the miRNA binding sites present within the 3′UTR region of the target mRNAs. The objective of this study was to design a PNA masking the binding site of the microRNA miR-145-5p present within the 3′UTR of the CFTR mRNA and to determine its activity in inhibiting miR-145-5p function, with particular focus on the expression of both CFTR mRNA and CFTR protein in Calu-3 cells. The results obtained support the concept that the PNA masking the miR-145-5p binding site of the CFTR mRNA is able to interfere with miR-145-5p biological functions, leading to both an increase of CFTR mRNA and CFTR protein content.

CONSTRUCTION OF NEGATIONS IN THE CONTEXT OF CRITICAL THINKING FOR PRIMARY SCHOOL

2018 ◽  
Vol 2 ◽  
pp. 454-463
Author(s):  
Anita Sondore ◽  
Elfrīda Krastiņa ◽  
Pēteris Daugulis ◽  
Elga Drelinga
Keyword(s):  
Critical Thinking ◽  
Primary School ◽  
Qualitative And Quantitative Analysis ◽  
Qualitative And Quantitative ◽  
Correct Usage ◽  
Study Results ◽  
Study Programs ◽  
Study Process ◽  
Primary School Pupils ◽  
Different Levels

In the modern study process it is important to teach pupils critical thinking and involvement in decision making. Formulation of negations and construction of counterexamples is one of the ingredients of critical thinking which are stressed in the new project of the mathematical standard for primary school „Skola 2030” in Latvia. The goal of this study is to analyze experience and skills of primary school pupils and students of teacher study programs, which are related to the ability to formulate negations and counterexamples. A qualitative and quantitative analysis of questionaire answers given by pupils and future teachers is performed in this study. Results of this study show that pupils make mistakes constructing negations and counterexamples. Teachers also have problems constructing correct assertions. These observations should stimulate universities to pay attention to teacher preparation in this sense. Teachers should teach correct usage of the negation operation at different levels of difficulty and correct construction of counterexamples.

An Integrated View of Strategic Management

2007 ◽  
Vol 18 (4) ◽  
pp. 275-302 ◽  
Author(s):  
Juan Pablo Stegmann
Keyword(s):  
Critical Thinking ◽  
Strategic Management ◽  
Market Power ◽  
Value Creation ◽  
Economic Value ◽  
Value Added ◽  
Integrative Model ◽  
Economic Value Added ◽  
Stock Value ◽  
Different Levels

Strategic management has produced an amazing number of theories and models in the last decades. However, so far it has not succeeded in producing a good integrative model that can synthesize all the existing models. In a previous paper I proposed such a model (from now on we will refer to it as the GEMK model, in relation to Growth-EVA-Market Power-Knowledge). It is based on the two drivers of stock value creation, Economic Value Added (EVA) and growth of capital, and proposes two new testable variables, market power and knowledge. This paper is the application of the GEMK model. It shows how most of existing strategic management models impact stock value creation. It produces a valuable simplification of the discipline, eliminates confrontations, shows that several different theories are complementary, provides a new powerful critical thinking, and shows that the different theories are contingent to these four variables. Most importantly, it shows that the different theories have different levels of impact on stock value creation.

scholarly journals Analysis of Critical Thinking Path of College Students Under STEAM Course

2021 ◽  
Vol 12 ◽  
Author(s):  
Jingrong Sha ◽  
Hong Shu ◽  
Zhaocao Kan
Keyword(s):  
College Students ◽  
Critical Thinking ◽  
Academic Engagement ◽  
Medium Level ◽  
Different Levels

This study examined the differences in critical thinking levels among students with different levels of academic engagement in STEAM courses. In this study, 30 college students were selected as subjects. Before experimenting, they received the academic engagement test and were divided into high, medium, and low groups based on their performance. Then, each group received three STEAM sessions and was asked to complete a topic discussion task. The results show that there are significant differences in the critical thinking level of students with different levels of academic engagement. Specifically, the students with a medium level of academic engagement had the highest critical thinking. Research has shown that the level of academic engagement affects the critical thinking of students in STEAM courses.

Critical Thinking in the Design Classroom: An Analysis of Student Design Reflections

2019 ◽  
Author(s):  
Emmeline Evans ◽  
Jessica Menold ◽  
Christopher McComb
Keyword(s):  
Critical Thinking ◽  
Clustering Analysis ◽  
Cognitive Process ◽  
Engineering Students ◽  
Procedural Knowledge ◽  
First Year ◽  
Reasoning Abilities ◽  
Different Levels ◽  
Insight Into ◽  
Future Growth

Abstract Within the domain of education, the term “critical thinking” is widely understood to mean the various skills that comprise an individual’s logical and reasoning abilities. It is critical that designers possess these abilities so that they can solve the complex problems of an increasingly interconnected world. In order to better understand patterns in engineering students’ critical thinking, this research applies the classifications of the 2001 revision of Bloom’s Taxonomy to 49 reflections written by first-year engineering students on a two-hour design practicum. Reflections were thematically coded to identify when students operated in different levels of the cognitive process and knowledge dimensions. Using k-means clustering analysis, genres of reflection were then determined. Four unique clusters of responses were identified. Notable trends in clusters included application and evaluation of procedural knowledge. Additionally, a difference was observed between the two largest clusters regarding deviance from the design process. While one cluster of responses generally minimized discussion of deviance, the second largest cluster emphasized this deviance, highlighting it as an opportunity for future growth. This work provides insight into how students learn design and how they communicate their learning, providing insight for instructors hoping to encourage deeper critical thinking in design courses.

scholarly journals CRITICAL THINKING AS ONE OF THE SKILLS DEVELOPED THROUGH THE DIALOGUE OR CONVERSATION

2021 ◽  
pp. 37-46
Keyword(s):  
Critical Thinking ◽  
Foreign Language ◽  
Teaching And Learning ◽  
Language Teaching ◽  
Speech Development ◽  
New Approaches ◽  
Different Levels ◽  
Language Teaching And Learning

The article is about the new approaches for teaching a foreign language among students of different levels and ages. It defines the main impact on language teaching and learning through critical thinking. As it is written in the article critical thinking can solve some problems of speech development. It enables students to accept the information and process it. Also, it helps learners to develop their logic thinking which is necessary in the informational era.

Modelo teórico para mensuração do pensamento crítico holístico no ensino do processo diagnóstico de enfermagem

2021 ◽  
Author(s):  
Fernando Riegel ◽  
Maria da Graça Oliveira Crossetti ◽  
Peter A. Facione
Keyword(s):  
Critical Thinking ◽  
Theoretical Model ◽  
Nursing Students ◽  
Formative Assessment ◽  
Assessment Tool ◽  
Diagnostic Process ◽  
Clinical Decisions ◽  
Nursing Science ◽  
Nursing Diagnoses ◽  
Different Levels

The theoretical model book for measuring holistic critical thinking (PCH) in the teaching of the nursing diagnostic process (PDE) highlights the complexity of the PDE based on the application of the PCH of nursing students in face of the requirement of making accurate clinical decisions; in addition, it demonstrates the applicability of the Holistic Critical Thinking Scoring Rubric (HCTSR) instrument authored by professors Peter A. Facione and Noreen Facione; for the assessment of holistic critical thinking in nursing and health, becoming an important diagnostic and formative assessment tool at different levels of education, which can contribute to the advancement of nursing science with regard to the training of critical nurses and reflective in the application of the nursing diagnostic process that is structured in the stages of investigation, interpretation and nursing diagnoses with a view to making accurate nursing decisions. To reach these stages, the nurse must develop skills of holistic critical thinking (PCH), in order to make decisions focused on the best results. Based on this theoretical model, it will be possible to implement different strategies to develop holistic critical thinking in teaching the diagnostic process according to the students' PCH level.

Abstract 12651: Fine-Tuning of Lung Thrombosis is a Therapeutic Strategy Against Inflammatory Lung Injury

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Colin E Evans ◽  
Xianming Zhang ◽  
Narsa Machireddy ◽  
You-yang Zhao
Keyword(s):  
Lung Injury ◽  
Therapeutic Strategy ◽  
Hypoxia Inducible Factor ◽  
Fine Tuning ◽  
Dependent Manner ◽  
Murine Models ◽  
Survival Gene ◽  
The Impact ◽  
Dose Dependent ◽  
Different Levels

Introduction: Lung thrombosis (LT) and endothelial cell (EC) death are positively associated with mortality in sepsis-induced acute lung injury (ALI) patients, but anti-coagulants have failed in clinical trials of sepsis. Hypothesis: We hypothesized that different levels of LT mediate ALI by regulating lung EC viability. Methods: To assess the impact of different levels of LT on ALI, we used murine models of LT and ALI. To explore how LT level might alter lung EC viability and ALI, we assessed survival gene expression by RNA sequencing. To identify the mechanism(s) responsible for changes in ALI after varying levels of LT, we assessed lung EC viability and ALI in mice with cell-specific knockout of different survival genes. Results: In platelet-depleted mice, LT was reduced while ALI was increased. Intra-venous microbeads were then administered to induce LT in a dose-dependent manner, showing that restoration of LT to the level found in platelet-replete mice protected against thrombocytopenia-induced ALI. We next showed in wild type mice, that while excessive increases in LT worsened ALI, induction of a mild level of LT conversely protected against ALI. The opposing impact of diminished or excessive versus mild LT on ALI was associated with changes in lung EC apoptosis. Subsequent studies showed a panel of candidate survival factors were differentially expressed in the lungs of ALI mice with or without mild or excessive LT. Mechanistically, we found that the protective impact of mild LT on ALI is dependent upon hypoxia-inducible factor (HIF) 1α in Tie2-expressing cells. Remarkably, the same mild level of LT retained its protective impact in platelet-depleted and platelet-replete mice even when induced up to 8 hours after sepsis. Conclusions: ALI is enhanced by diminished or excessive LT but suppressed by mild LT through HIF1α. The control of LT represents a therapeutic strategy for the induction of a pro-survival response that protects against inflammatory lung injury.

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