The Relationship Between Bacteria and Breast Cancer: Focusing on the Common Staphylococcus aureus

2019 ◽  
Vol 9 (11) ◽  
pp. 1571-1574
Author(s):  
A. Na-Er ◽  
Yunhong Liu ◽  
Yanjun Gan

Background: The risk of post-operative infection still accounts for a high proportion among the patients. The peptidoglycan on Staphylococcus aureus promotes cellular invasiveness and adhesiveness of tumor cells by pathways activation, including NF-kB, STAT3 and Smad3. Methods: This study included 132 patients age ranging from 45–55 that have been diagnosed with IIA phase breast cancer based on the TNM classification system in one hospital located in the relatively high-income area. These patients have been scheduled the operations and are distributed into two groups: one group will be given certain dosage of antibiotics on presumed Staphylococcus aureus infections, and another group will not be given any unnecessary antibiotics before surgery. Results: We found that 6 patients present surgical site infection related Staphylococcus aureus, with 1 patient in the antibiotics group and the other 5 patients are in the non-antibiotics group. Within the one-year period after surgery, 4 patients presented with metastasis to adjacent lymph nodes, 3 patients are in the non-antibiotics group and another one in the antibiotics group. Conclusion: Early intervention could be an accessible method to decrease the incidence of surgical site infection, which has been illustrated in this study. We consider to take preventive dosage of antibiotics before surgery, which could improve the prognosis of breast cancer and their quality of life in a larger extent.

Author(s):  
Francesco Giovanni Brugnaro

With his report, Mons. Francesco Giovanni Brugnaro, Archbishop of Camerino - San Severino Marche, offers a personal testimony of his experience as a priest, friend and colleague of the Rectoral Prof. Paolo Mantegazza, who he met in the years ‘89-’95 during his chaplain service at the Rectory of Santa Maria Annunciata of the University of Milan. In addition to the affectionate and grateful remembrance towards the exemplary role of rector, father and teacher, he adds some characteristics regarding the relationship that Prof. Mantegazza knew to weave with the university students, careful to consider the person as a whole rather than as a subject impersonal and anonymous. This special attention stemmed from the profound conviction that education is much more than simple teaching. He introduced in his long experience as a teacher the one that transformed his courses into real schools of life: the human and ethical contribution to face the most difficult future challenges in the professional field. For this reason he was also a great mediator for the very talented teachers to keep the relationship between scientific and didactic research high, between the quality of the preparation for the doctorate-specialization and the moral and methodological seriousness of the future professional. In the memory of Mons. Brugnaro, the pain that struck the Mantegazza family for the tragic and premature disappearance of the two beloved sons is preserved. Inspired also by Don Giussani’s charism, together with his wife Andreina, he was able to transform that lacerating pain into an exemplary witness of Christian life founded on the Resurrection of Christ. The common attendance of the Archbishop of Milan from 1979 to 2002, allowed both to live a daily faith, drawn from the prophetic vision of the biblical pastoral of Card. Martini also within the University, stimulating the chair of non-believers.


2019 ◽  
Vol 4 (3) ◽  
Author(s):  
Molly Vasanthakumar

PICO questionIn animals undergoing surgery, does the use of disposable synthetic drapes reduce the risk of surgical site infections when compared to reusable woven drapes?Clinical bottom lineCurrent literature on the risk of surgical site infection with disposable and reusable drapes in animals is limited. Three human studies were reviewed, one systematic review and two controlled trials. Both these study types generally provide high levels of evidence; however their individual limitations reduce the quality of their data. Overall the results were mixed, and due to the small number of reviewed papers and the fact that only one study specifically measured surgical site infection as the outcome, it is not possible to conclude that disposable drapes reduce the risk of surgical site infections (SSI) when compared to reusable drapes.The impact of the veterinary profession on the ecosystem is often ignored. When following the One Health concept, vets must consider the ecological impact of clinical decisions. Choosing reusable drapes for certain clean, elective procedures may be a way to reduce waste without compromising the health of patients.


2020 ◽  
Vol 26 (11) ◽  
pp. 2567-2593
Author(s):  
M.V. Pomazanov

Subject. The study addresses the improvement of risk management efficiency and the quality of lending decisions made by banks. Objectives. The aim is to present the bank management with a fair algorithm for risk management motivation on the one hand, and the credit management (business) on the other hand. Within the framework of the common goal to maximize risk-adjusted income from loans, this algorithm will provide guidelines for ‘risk management’ and ‘business’ functions on how to improve individual and overall efficiency. Methods. The study employs the discriminant analysis, type I and II errors, Lorentz curve modeling, statistical analysis, economic modeling. Results. The paper offers a mechanism for assessing the quality of risk management decisions as opposed to (or in support of) decisions of the lending business when approving transactions. The mechanism rests on the approach of stating type I and II errors and the corresponding classical metric of the Gini coefficient. On the ‘business’ side, the mechanism monitors the improvement or deterioration of the indicator of changes in losses in comparison with the market average. Conclusions. The study substantiates the stimulating ‘rules of the game’ between the ‘business’ and ‘risk management’ to improve the efficiency of the entire business, to optimize interactions within the framework of internal competition. It presents mathematical tools to calculate corresponding indicators of the efficiency of internally competing entities.


Cancers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 3141
Author(s):  
Aurora Laborda-Illanes ◽  
Lidia Sánchez-Alcoholado ◽  
Soukaina Boutriq ◽  
Isaac Plaza-Andrades ◽  
Jesús Peralta-Linero ◽  
...  

In this review we summarize a possible connection between gut microbiota, melatonin production, and breast cancer. An imbalance in gut bacterial population composition (dysbiosis), or changes in the production of melatonin (circadian disruption) alters estrogen levels. On the one hand, this may be due to the bacterial composition of estrobolome, since bacteria with β-glucuronidase activity favour estrogens in a deconjugated state, which may ultimately lead to pathologies, including breast cancer. On the other hand, it has been shown that these changes in intestinal microbiota stimulate the kynurenine pathway, moving tryptophan away from the melatonergic pathway, thereby reducing circulating melatonin levels. Due to the fact that melatonin has antiestrogenic properties, it affects active and inactive estrogen levels. These changes increase the risk of developing breast cancer. Additionally, melatonin stimulates the differentiation of preadipocytes into adipocytes, which have low estrogen levels due to the fact that adipocytes do not express aromatase. Consequently, melatonin also reduces the risk of breast cancer. However, more studies are needed to determine the relationship between microbiota, melatonin, and breast cancer, in addition to clinical trials to confirm the sensitizing effects of melatonin to chemotherapy and radiotherapy, and its ability to ameliorate or prevent the side effects of these therapies.


Elenchos ◽  
2020 ◽  
Vol 41 (1) ◽  
pp. 181-194
Author(s):  
Angela Longo

AbstractThe following work features elements to ponder and an in-depth explanation taken on the Anca Vasiliu’s study about the possibilities and ways of thinking of God by a rational entity, such as the human being. This is an ever relevant topic that, however, takes place in relation to Platonic authors and texts, especially in Late Antiquity. The common thread is that the human being is a God’s creature who resembles him and who is image of. Nevertheless, this also applies within the Christian Trinity according to which, not without problems, the Son is the image of the Father. Lastly, also the relationship of the Spirit with the Father and the Son, always within the Trinity, can be considered as a relationship of similarity, but again not without critical issues between the similarity of attributes, on the one hand, and the identity of nature, on the other.


Religions ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 199
Author(s):  
Maria Ledstam

This article engages with how religion and economy relate to each other in faith-based businesses. It also elaborates on a recurrent idea in theological literature that reflections on different visions of time can advance theological analyses of the relationship between Christianity and capitalism. More specifically, this article brings results from an ethnographic study of two faith-based businesses into conversation with the ethicist Luke Bretherton’s presentation of different understandings of the relationship between Christianity and capitalism. Using Theodore Schatzki’s theory of timespace, the article examines how time and space are constituted in two small faith-based businesses that are part of the two networks Business as Mission (evangelical) and Economy of Communion (catholic) and how the different timespaces affect the religious-economic configurations in the two cases and with what moral implications. The overall findings suggest that the timespace in the Catholic business was characterized by struggling caused by a tension between certain ideals on how religion and economy should relate to each other on the one hand and how the practice evolved on the other hand. Furthermore, the timespace in the evangelical business was characterized by confidence, caused by the business having a rather distinct and achievable goal when it came to how they wanted to be different and how religion should relate to economy. There are, however, nuances and important resemblances between the cases that cannot be explained by the businesses’ confessional and theological affiliations. Rather, there seems to be something about the phenomenon of tension-filled and confident faith-based businesses that causes a drive in the practices towards the common good. After mapping the results of the empirical study, I discuss some contributions that I argue this study brings to Bretherton’s presentation of the relationship between Christianity and capitalism.


Author(s):  
Dr Rose Fazli ◽  
Dr Anahita Seifi

The present article is an attempt to offer the concept of political development from a novel perspective and perceive the Afghan Women image in accordance with the aforementioned viewpoint. To do so, first many efforts have been made to elucidate the author’s outlook as it contrasts with the classic stance of the concept of power and political development by reviewing the literature in development and particularly political development during the previous decades. For example Post-World War II approaches to political development which consider political development, from the Hobbesian perspective toward power, as one of the functions of government. However in a different view of power, political development found another place when it has been understood via postmodern approaches, it means power in a network of relationships, not limited to the one-way relationship between ruler and obedient. Therefore newer concept and forces find their way on political development likewise “image” as a considerable social, political and cultural concept and women as the new force. Then, the meaning of “image” as a symbolic one portraying the common universal aspect is explained. The Afghan woman image emphasizing the historic period of 2001 till now is scrutinized both formally and informally and finally the relationship between this reproduced image of Afghan women and Afghanistan political development from a novel perspective of understanding is represented.


2018 ◽  
Vol 71 (suppl 3) ◽  
pp. 1395-1403
Author(s):  
Marcia Regina Cunha ◽  
Maria Clara Padoveze ◽  
Célia Regina Maganha e Melo ◽  
Lucia Yasuko Izumi Nichiata

ABSTRACT Objective: To describe the profile of women in relation to their living conditions, health status and socio-demographic profile, correlating it with the presence of signs and symptoms suggestive of post-cesarean surgical site infection, identifying information to be considered in the puerperium consultation performed by nurses and proposing a roadmap for the systematization of care. Method: Quantitative, exploratory, descriptive, cross-sectional and retrospective review of medical records of women who had cesarean deliveries in 2014, in the city of São Paulo. Results: 89 medical records were analyzed, 62 of them with incomplete information. In 11, there was at least one of the signs and symptoms suggestive of infection. Conclusion: Given the results of the study, the systematization of puerperal consultation is essential. The roadmap is an instrument that can potentially improve the quality of service and the recording of information.


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