Antibacterial performance of Berberine loaded carrageenan/konjac glucomannan hydrogels

2021 ◽  
Vol 11 (9) ◽  
pp. 1516-1522
Author(s):  
Lei Jiang ◽  
Qiuxian Chen ◽  
Jia Liu ◽  
Zhongjie Zhu ◽  
Wei Shao
Keyword(s):  
Antibacterial Effect ◽  
Three Dimensional ◽  
Konjac Glucomannan ◽  
High Porosity ◽  
Release Behavior ◽  
Cell Compatibility ◽  
Antibacterial Materials ◽  
Antibacterial Performance ◽  
Dimensional Network ◽  
Good Cell

Carrageenan and konjac glucomannan are non-toxic polysaccharides which have been widely applied in the biomedical fields. Berberine as the antibacterial agent was successfully loaded into carrageenan/konjac glucomannan hydrogels. The Berberine loaded carrageenan/konjac glucomannan dried hydrogels display three-dimensional network structure, good swelling behavior and high porosity. These dried hydrogels also show controlled release behavior of Berberine. A good antibacterial effect towards S. aureus and C. albicans with good cell compatibility is exhibited. Thus, the fabricated Berberine loaded carrageenan/konjac glucomannan dried hydrogels could be considered as novel antibiotic alternative antibacterial materials.

New Advances in Graphene-Based Three-Dimensional Structures

2022 ◽  
pp. 101-128
Author(s):  
Javier Cencerrero Fernández del Moral ◽  
Amaya Romero Izquierdo ◽  
Paula Sánchez Paredes ◽  
Osmín Avilés-García ◽  
Israel Fernandez-Reina
Keyword(s):  
Surface Area ◽  
Environmental Remediation ◽  
Three Dimensional ◽  
Single Atom ◽  
Synthesis Methods ◽  
High Porosity ◽  
Covalent Bonds ◽  
Dimensional Network ◽  
Wide Range ◽  
Electron Transfer Properties

Graphene is defined as a two-dimensional network of carbon atoms with a single atom thickness and a hexagonal crystalline structure with sp2 hybridization compacted by covalent bonds. Due to its structure and geometry, graphene has unique properties, including a large specific surface area, rapid mobility of load carriers, and high thermal and electrical conductivity. However, these characteristics are limited due to the restructuring of graphene sheets. For this reason, there are many studies devoted to the synthesis of three-dimensional structures that prevent the agglomeration of the sheets and the loss of properties of the graphene structure. These three-dimensional structures have low density, high porosity and surface area, stable mechanical properties, and good mass and electron transfer properties. This chapter aims to summarize the synthesis methods of the different three-dimensional structures derived from graphene as well as their wide range of applications in environmental remediation, sensors, biomedical and energy-related applications, among many others.

scholarly journals Batch preparation and characterization of ZnO/PLGA/PCL nanofiber membranes for antibacterial materials

2021 ◽  
Author(s):  
Siqi Li ◽  
Jing Yin ◽  
Lan Xu
Keyword(s):  
Antibacterial Effect ◽  
Weight Ratio ◽  
Batch Preparation ◽  
Antibacterial Materials ◽  
Antibacterial Performance ◽  
Surgical Suture ◽  
Low Toxicity ◽  
Nanofiber Membranes ◽  
High Output

As biomaterials with excellent biocompatibility, biodegradation and low toxicity, poly(ε-caprolactone) (PCL) and poly(lactic-co-glycolic acid) (PLGA) are widely applied as wound dressing and surgical suture in biomedical field. In this paper, an oblique section free surface eletrospinning (OSFSE) apparatus was utilized to prepare high-quality and high-output ZnO/PLGA/PCL nanofiber membranes (NFMs) for antibacterial materials. The effects of the weight ratio of PLGA and PCL on the viscosity and conductivity of electrospinning solutions as well as the yield, morphology and wettability of PLGA/PCL NFMs were researched, and the optimal weight ratio of 6:4 was determined. Then the effects of ZnO contents on the electrospinning solution properties as well as the yield, morphology, structure, wettability, mechanical property and antibacterial performance of ZnO/PLGA/PCL NFMs with the optimal ratio of PLGA and PCL were studied. The results indicated that the addition of ZnO could improve significantly the antibacterial effect of NFMs, and the NFMs with 3 wt% ZnO had excellent antibacterial activity against E. coli (95.3%) and S. aureus (95.7%).

scholarly journals Preparation and Characterization of Gaphene-Doped Carbon-Aerogel Electrode

2022 ◽  
Vol 2160 (1) ◽  
pp. 012003
Author(s):  
Zhengshun Wang ◽  
Kaizheng Wang ◽  
Jianzhen Mao ◽  
Zaiyong Jiang
Keyword(s):  
Electrode Materials ◽  
Three Dimensional ◽  
Carbon Aerogel ◽  
High Specific Surface Area ◽  
Carbon Aerogels ◽  
Porous Carbon Material ◽  
Low Density ◽  
High Porosity ◽  
Dimensional Network

Abstract Carbon-aerogel is a kind of nano-porous carbon material with special three-dimensional network structure. Electrode materials with high specific surface area, high porosity, superior conductivity and low density were obtained by adding graphene to prepare graphene-doped carbon-aerogels.

scholarly journals Preparation and Electrocatalysis Application of Pure Metallic Aerogel: A Review

Catalysts ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 1376
Author(s):  
Ran Zhang ◽  
Yan Zhao
Keyword(s):  
Active Sites ◽  
Synergetic Effect ◽  
Three Dimensional ◽  
Utilization Efficiency ◽  
High Porosity ◽  
Quantum Size ◽  
Dimensional Network ◽  
High Utilization ◽  
Preparation Strategy ◽  
Catalytic Performances

Nanomaterials are widely used in electrocatalysts due to their quantum size effect and high utilization efficiency. There are two ways to improve the activity of nanoelectrocatalysts: increasing the number of active sites and improving the inherent activity of each catalytic site. The structure of the catalyst itself can be improved by increasing the number of exposed active sites per unit mass. The high porosity and three-dimensional network structure enable aerogels to have the characteristics of a large specific surface area, exposing many active sites and bringing structural stability through the self-supporting nature of aerogels. Thus, by adjusting the compositions of aerogels, the synergetic effect introduced by alloy elements can be utilized to further improve the single-site activity. In this review, we summarized the basic preparation strategy of aerogels and extended it to the preparation of alloys and special structure aerogels. Moreover, through the eight electrocatalysis cases, the outstanding catalytic performances and broad applicability of aerogel electrocatalysts are emphasized. Finally, we predict the future development of pure metallic aerogel electrocatalysts from the perspective of preparation to application.

scholarly journals Synthesis of Antibacterial Gelatin/Sodium Alginate Sponges and Their Antibacterial Activity

Polymers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 1926
Author(s):  
Yanyi Wen ◽  
Bing Yu ◽  
Zhongjie Zhu ◽  
Zhuoran Yang ◽  
Wei Shao
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Antibacterial Activity ◽  
Three Dimensional ◽  
Gram Negative Bacteria ◽  
High Porosity ◽  
Gram Negative ◽  
Good Antibacterial Activity ◽  
Dimensional Network ◽  
Scanning Electron

In the present study, sponges with the antibiotic tetracycline hydrochloride (TCH) loaded into alginate incorporated with gelatin (G/SA) were fabricated. The G/SA sponges were characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and thermogravimetric (TG) analysis. G/SA sponges show a three-dimensional network structure with high porosity. An excellent swelling behavior and a controlled TCH release performance are observed from G/SA sponges. Moreover, they exhibit good antibacterial activity against both Gram-positive and Gram-negative bacteria.

Preparation of graphene oxide with silver nanowires to enhance antibacterial properties and cell compatibility

RSC Advances ◽  
2015 ◽  
Vol 5 (104) ◽  
pp. 85748-85755 ◽  
Author(s):  
Jianghu Cui ◽  
Yingliang Liu
Keyword(s):  
Graphene Oxide ◽  
Hydrothermal Method ◽  
Antibacterial Effect ◽  
Silver Nanowires ◽  
Antibacterial Properties ◽  
Cell Compatibility ◽  
Good Cell ◽  
Graphene Oxide Sheets

Ag NWs were evenly distributed on the surface of graphene oxide sheets via a hydrothermal method. The prepared composites exhibited an enhanced antibacterial effect and good cell compatibility.

scholarly journals Hollow polydimethylsiloxane (PDMS) foam with a 3D interconnected network for highly sensitive capacitive pressure sensors

2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Dong Hwan Kim ◽  
Young Jung ◽  
Kyungkuk Jung ◽  
Dong Hwa Kwak ◽  
Dong Min Park ◽  
...  
Keyword(s):  
Network Structure ◽  
Three Dimensional ◽  
Pressure Sensors ◽  
High Sensitivity ◽  
High Porosity ◽  
Capacitive Pressure Sensor ◽  
Interconnected Network ◽  
Dimensional Network ◽  
Highly Sensitive ◽  
Output Characteristics

AbstractWe propose a highly sensitive capacitive pressure sensor made of hollow polydimethylsiloxane (PDMS) foam with a three-dimensional network structure. The stiffness of the foam is adjusted by the viscosity of the PDMS solution. The fabricated PDMS-30 (PDMS 30 wt%) foam shows extremely high porosity (> 86%) approximately 19 times that of bare PDMS (PDMS 100 wt%) foam. Capacitive pressure sensors fabricated using the foam possess high sensitivity, good compressibility (up to 80% strain), and consistent output characteristics in a 2000-cycle test.

Development of Mucoadhesive Buccal Drug Delivery System of Propranolol Hydrochloride Using Aster ericoides Mucilage

2020 ◽  
Vol 10 (2) ◽  
pp. 133-148
Author(s):  
Ankaj Kaundal ◽  
Pravin Kumar ◽  
Rajendra Awasthi ◽  
Giriraj T. Kulkarni
Keyword(s):  
Buccal Cavity ◽  
Three Dimensional ◽  
Hot Water ◽  
Fickian Diffusion ◽  
Aster Ericoides ◽  
Dimensional Network ◽  
Buccal Tablet ◽  
Significant Difference ◽  
Volunteer Group

Aim: The study was aimed to develop mucoadhesive buccal tablets using Aster ericoides leaves mucilage. Background : Mucilages are naturally occurring high-molecular-weight polyuronides, which have been extensively studied for their application in different pharmaceutical dosage forms. Objective: The objective of the present research was to establish the mucilage isolated from the leaves of Aster ericoides as an excipient for the formulation of the mucoadhesive buccal tablet. Method: The mucilage was isolated from the leaves of Aster ericoides by maceration, precipitated with acetone and characterized. Tablets were prepared using wet granulation technique and evaluated for various official tests. Results: The mucilage was found to be non-toxic on A-431 and Vero cell lines. It was insoluble but swellable in cold and hot water. The results indicate that mucilage can form a three-dimensional network. The pH of the mucilage (6.82 ± 0.13) indicated that it might be non-irritant to the buccal cavity. The mucilage was found to be free from microbes. The release of drug was by Fickian diffusion. The in vivo buccal tablet acceptance was 80%. No significant difference between the diastolic blood pressure of standard and Aster tablets treated volunteer group was recorded. Conclusion: The mucilage was found to be non-toxic on A-431 and Vero cell lines. It was insoluble but swellable in cold and hot water. The results indicate that mucilage can form a three-dimensional network. The pH of the mucilage (6.82 ± 0.13) indicated that it might be non-irritant to the buccal cavity. The mucilage was found to be free from microbes. The release of drug was by Fickian diffusion. The in vivo buccal tablet acceptance was 80%. No significant difference between the diastolic blood pressure of standard and Aster tablets treated volunteer group was recorded. Other: However, to prove the potency of the polymer, in vivo bioavailability studies in human volunteers are needed along with chronic toxicity studies in suitable animal models.

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