LXIII. Frontal Sinus Empyema in Young Children, with Several Case Reports

1927 ◽  
Vol 36 (3) ◽  
pp. 693-700
Author(s):  
Irving Martin Lupton
2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Michael S. Scheeringa ◽  
Lauren C. Burns

Generalized anxiety disorder (GAD) is purported to start in early childhood but concerns about attenuation of anxiety symptoms over time and the development of emerging cognitive and emotional processing capabilities pose multiple challenges for accurate detection. This paper presents the first known case reports of very young children with GAD to examine these developmental challenges at the item level. Three children, five-to-six years of age, were assessed with the Diagnostic Infant and Preschool Assessment twice in a test-retest reliability study. One case appeared to show attenuation of the worries during the test-retest period based on caregiver report but not when followed over two years. The other two cases showed stability of the full complement of diagnostic criteria. The cases were useful for demonstrating that the current diagnostic criteria appear adequate for this developmental period. The challenges of accurate assessment of young children that might cause missed diagnoses are discussed. Future research on the underlying dysregulation of negative emotionality and long-term follow-ups are needed to better understand the etiology, treatment, and course of GAD in this age group.


PEDIATRICS ◽  
1989 ◽  
Vol 83 (1) ◽  
pp. A54-A54
Author(s):  
Student

1. The preliminary issue to be determined by the court is, can pertussis vaccine cause permanent brain damage in young children? The question relates to pertussis vaccine manufactured in the United Kingdom and applies to all children whether or not they were neurologically normal before vaccination. The burden of proof rests on the Plaintiff and the standard of proof is that of the balance of probability. It must be shown that it is more likely than not that the vaccine can cause permanent brain damage. 2. The medical and expert opinion is deeply divided on the issue. 3. The question is not answered by showing that there is a respectable and responsible body of medical opinion that the vaccine can, albeit rarely, cause permanent brain damage, or that this view is/may be more widely held than the contrary. 4. Similarly the advice contained in the contra-indications against pertussis vaccination . . . cannot be relied upon as though it were evidence . . . that the vaccine in fact causes permanent brain damage. 5. Reports of . . . encephalopathy resulting in . . . brain damage or death where the onset occurs shortly after DTP vaccination, raises the hypothesis that the vaccine may cause brain damage or death. It does not prove the hypothesis. Such reports do not take account of events occurring by chance, for which no explanation can be found. What they do establish is that encephalopathy resulting occasionally in permanent brain damage or death does sometimes occur in close temporal proximity to pertussis vaccination. 6. I have reviewed the evidence and reasoning of the Plaintiffs and Defendants' expert witnesses . . . . I have found myself more impressed both by the cogency and quality of the evidence and reasoning of the experts called on behalf of the Defendants. 7. When I embarked on consideration of the preliminary issue, I was impressed by the case reports and what was evidently a widely held belief that the vaccination could, albeit rarely, cause permanent brain damage. I was ready to accept that this belief was well founded. But over the weeks that I have listened to and examined the evidence and arguments, I have become more and more doubtful that this is so. I have now come to the clear conclusion that the Plaintiff fails to satisfy me on the balance of probability that pertussis vaccine can cause permanent brain damage in young children. It is possible it does, the contrary cannot be proved. But in the result the Plaintiff's claim must fail.


CytoJournal ◽  
2013 ◽  
Vol 10 ◽  
pp. 20 ◽  
Author(s):  
Anitha Ann Thomas ◽  
Felicia Tze Yee Goh

Presence of bone marrow elements in cerebrospinal fluid is rare. Journal publications on this topic are few and majority of them were written over a decade ago mostly as case reports in young children or the elderly. The increased cellularity and presence of myeloid precursors can be a pitfall and may be misdiagnosed as leukemia or lymphoma or central nervous system infection, when the specimen is actually not representative. With the intention to create awareness of potential pitfalls and avoid erroneous diagnoses, as well as adding on to the current photo archive of bone marrow elements in CSF, we present a recent case of bone marrow contaminants in the CSF of a 16-year-old girl.


2009 ◽  
Vol 62 (2) ◽  
pp. 272-273 ◽  
Author(s):  
Ramón Luaces-Rey ◽  
Álvaro García-Rozado ◽  
José Luís Crespo Escudero ◽  
Beatriz Patiño Seijas ◽  
Jorge Arenaz Búa ◽  
...  

PEDIATRICS ◽  
1968 ◽  
Vol 42 (5) ◽  
pp. 837-840
Author(s):  
Joseph D. Dickerman ◽  
William Bishop ◽  
James F. Marks

Acute alcoholism is an important cause of morbidity and mortality in adults. The signs and symptoms of acute ethanol intoxication and the metabolic fate of ethanol in the body are well known.1 There are a few case reports of alcohol-induced hypoglycemia in young children2 and also case reports of withdrawal symptoms in infants of alcoholic mothers.3 Yet there is very little in the literature on the course, treatment, and prognosis of children with acute poisoning due to accidental alcohol ingestion. This report is designed to call attention to this entity, to describe a case whose blood alcoholic level was, as far as we know, the highest recorded in the pediatric literature in a survivor, to Suggest a mode of therapy, and, hopefully, to awaken pediatricians to thew possibility of ethanol intoxication in young children.


2017 ◽  
Vol 36 (01) ◽  
pp. 26-28
Author(s):  
Benedito Pereira ◽  
Radmila Holanda ◽  
José Targino Neto ◽  
Luciano Holanda

AbstractA 25-year-old patient was admitted to the emergency room presenting headaches after a traumatic brain injury (TBI) 30 days before, when he collided frontally with another driver. After a skull radiography, the presence of a foreign body was observed in the frontal sinus. A cranial computed tomography (CT) scan found that it was a tooth. The patient underwent surgical treatment for the removal of the tooth. Traumatic brain injury caused by non-missile penetrating objects is unusual, and has been described in case reports in the literature. To the best of our knowledge, no similar reports can be found in the literature.


1993 ◽  
Vol 27 (5) ◽  
pp. 579-581 ◽  
Author(s):  
Baziel G.M. van Engelen ◽  
Jules S. Gimbrere ◽  
Leo H. Booy

OBJECTIVE: To report the occurrence of recurrent benzodiazepine withdrawal reactions in two very young children following discontinuation of sedation with midazolam. CASE SUMMARY: A 15-month-old boy with apneic episodes was sedated with midazolam for 12 days with constant infusion. Half a day after discontinuation of the midazolam the boy became restless, tachycardic, and hyperpyrexia. When midazolam was readministered, all symptoms disappeared. Four days later midazolam was again discontinued and within 12 hours the same signs and symptoms reappeared. Midazolam infusion was restarted, and the signs and symptoms disappeared for the second time. After thoracotomy, a 14-day-old boy received intravenous midazolam for sedation for 29 days. Within 12 hours after discontinuation of midazolam he became restless, developed a bulging stomach secondary to aerophagia, and was vomiting. Midazolam therapy was reinstituted and continued for another 2 months by constant infusion. Thereafter, the boy was successfully weaned from artificial ventilation in 5 days under sedation with midazolam. About 12 hours after discontinuation of midazolam the boy became restless, tachycardic, again developed a bulging stomach because of aerophagia, and vomited. When the child was sedated with clorazepate by continuous infusion, the signs and symptoms disappeared. DISCUSSION: Case reports describing benzodiazepine withdrawal reaction upon discontinuation of midazolam were reviewed and compared. The symptoms observed in the children we present resemble those mentioned in the three children and two adults reported previously. Unique in the very young children in this article is the occurrence of gastrointestinal symptoms, which most likely are the result of air being swallowed secondary to severe agitation. CONCLUSIONS: Midazolam withdrawal reactions in adults and children, particularly in an intensive care unit, can be significant. Considerable caution must be taken with relatively long-term administration and abrupt discontinuation of midazolam.


2021 ◽  
pp. 1-5
Author(s):  
Emily S. Misch ◽  
Christina Stevens ◽  
Emily S. Misch ◽  
Anne Getz ◽  
Eric Hink ◽  
...  

Fibrous dysplasia (FD) is an uncommon non-malignant bony tumor in which normal bone is replaced by disorganized fibro-osseous tissue. It most often involves the femur, ribs, and craniofacial skeleton and is commonly diagnosed in adolescence or early adulthood. Involvement of the paranasal sinuses is rare, and there is a relative paucity of case reports in the literature. Here, we report a case of FD of the frontal sinus in a 22-year-old male initially presenting with acute onset periorbital emphysema after nose-blowing. Radiographic examination revealed an expansile lesion with “ground-glass” appearance. The patient underwent resection and reconstruction by combined endoscopic and external approach with osteoplastic flap by a multidisciplinary team. The diagnosis of FD was confirmed by permanent histopathology. This report reviews the presentation and treatment of FD of the paranasal sinuses and details a combined external and endoscopic approach to resection of the frontal sinus mass.


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