Factors Related to Microalbuminuria in Nondiabetic Elderly Males with Normal Renal Function

2005 ◽  
Vol 40 (11) ◽  
pp. 972-976
Author(s):  
Jeanne E. Frenzel ◽  
Ji M. Koo ◽  
Tze Shien Lo ◽  
Rajeev Kaul ◽  
Amandeep Chadha
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Body Mass Index ◽  
Renal Function ◽  
Serum Lipid ◽  
Cardiovascular Events ◽  
Significant Risk ◽  
Adult Males ◽  
Lipid Levels ◽  
Elderly Males

Two hundred and three adult males were evaluated for the presence of microalbuminuria. Out of 203 patients, 123 (61%) tested negative for microalbuminuria and 80 (39%) tested positive. Patients were further evaluated for age, body mass index, cigarette smoking, blood pressure, serum lipid levels, renal function, cardiovascular events, and use of antihypertensive and antihyperlipidemic medications. This study shows that age greater than 70 years, creatinine clearance less than 50 mL/min, and systolic blood pressure greater than or equal to 140 mm Hg are all significant risk factors for microalbuminuria.

scholarly journals An Overview on Cardiovascular Risks Definitions by Using Survival Analysis Techniques-Tehran Lipid and Glucose Study: 13-Year Follow-Up Outcomes

2016 ◽  
Vol 9 (4) ◽  
pp. 197
Author(s):  
Nezhat Shakeri ◽  
Farhad Hajsheikholeslami ◽  
Amir abbas Momenan ◽  
Fereidoun Azizi
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Blood Sugar ◽  
Elderly Population ◽  
Significant Risk ◽  
Fasting Blood Sugar ◽  
Cardiovascular Risks ◽  
Elderly Males ◽  
Definition Of

<p>Risk assessment is an important issue for starting medication for patients. Literature reveals that diabetes, hypertension, dyslipidemia and Body Mass Index (BMI) are among major risk factors for longevity. Since the cut-off points proposed in various sources are generally irrespective of age, sex and race, it has been attempted to validate current definitions for Tehran’s elderly population by using a prospective cohort study. For this purpose, one thousand seven hundred and ninety eight (1,798) individuals above 60 years old were recruited in the primary phase of the Tehran Lipid and Glucose Study (TLGS) during 1998-2001, and were tested for their systolic and diastolic blood pressure, total cholesterol, LDL cholesterol, high density lipoprotein cholesterol (HDL), triglyceride (TG), fasting blood sugar (FBS), 2-h plasma glucose (2HPG) and some other factors at the time of entry to the study. They were followed up for 13 years and their vital statuses were registered (1998-2011).</p><p>According to the standard definition of diabetes, dyslipidemia and hypertension, the participants were divided into ill and healthy groups. By using univariate Cox proportional hazard model, a 95% hazard ratio for various risk factors was estimated. Cut-off points of 126 mg/dL for fasting blood sugar or 200 mg/dL for 2HPG for defining diabetes were identified as appropriate points for predicting longevity for elderly males and females. Systolic blood pressure over 140 mmHg or diastolic blood pressure over 90 mmHg or having medication as a definition of hypertension were identified as a significant risk factor for elderly males only. Dyslipidemia which is defined based on Cholesterol&gt;240 or TG&gt;400 or LDL&gt;160 or HDL&lt;35, was not identified as a longevity predictor for elderly men and women. The results showed that BMI&gt;31 Kg/m<sup>2</sup> at the time of entry to the study significantly reduced the survival time of women. In conclusion, the definitions of diseases like hypertension and dyslipidemia based on cut-off points don’t classify the Tehran’s elderly population accurately. More investigation in this regard is required.</p>

Tracking of Serum Lipid Levels, Blood Pressure, and Body Mass Index from Childhood to Adulthood: The Cardiovascular Risk in Young Finns Study

2011 ◽  
Vol 159 (4) ◽  
pp. 584-590 ◽  
Author(s):  
Jonna Juhola ◽  
Costan G. Magnussen ◽  
Jorma S.A. Viikari ◽  
Mika Kähönen ◽  
Nina Hutri-Kähönen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Cardiovascular Risk ◽  
Body Mass ◽  
Serum Lipid ◽  
Lipid Levels ◽  
Serum Lipid Levels ◽  
Young Finns Study

Fibrinogen and Factor Vllag in Healthy Adolescents: The Floren-teen (Florence Teenager) Study

1996 ◽  
Vol 75 (05) ◽  
pp. 778-781 ◽  
Author(s):  
Domenico Prisco ◽  
Sandra Fedi ◽  
Tamara Brunelli ◽  
Anna Paola Cellai ◽  
Mohamed Isse Hagi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Healthy Subjects ◽  
Cardiovascular Events ◽  
Independent Risk Factor ◽  
Factor Vii ◽  
Coronary Heart Disease Prevention ◽  
Familial History ◽  
Clear Cut ◽  
Adolescent Population

SummaryAt least five studies based on more than twenty thousand healthy subjects indicated that fibrinogen is an independent risk factor for cardiovascular events; less clear-cut is the relation between factor VII and risk for arterial thrombotic disorders, which was demonstrated in two of the three studies investigating this association. However, no study has investigated the behaviour of fibrinogen and factor VII in an adolescent population. In a study of Preventive Medicine and Education Program, fibrinogen (clotting method) and factor Vllag (ELISA), in addition to other metabolic parameters, life-style and familial history, were investigated in 451 students (313 females and 138 males, age 15-17 years) from two high schools of Florence. Fibrinogen levels were significantly higher in women than in men, whereas factor Vllag levels did not significantly differ. Both fibrinogen and factor Vllag significantly correlated with total cholesterol (p <0.05) while only fibrinogen correlated with body mass index (p <0.01). Factor Vllag was significantly correlated with systolic blood pressure (p <0.001). This study provides information on coagulation risk factors in a population of adolescents which may be of importance in planning coronary heart disease prevention programs.

Haematocrit: Relationships with Blood Lipids, Blood Pressure and other Cardiovascular Risk Factors

1994 ◽  
Vol 72 (01) ◽  
pp. 058-064 ◽  
Author(s):  
Goya Wannamethee ◽  
A Gerald Shaper
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Blood Pressure ◽  
Body Mass Index ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Alcohol Intake ◽  
Blood Lipids ◽  
The Other ◽  
The Relationship

SummaryThe relationship between haematocrit and cardiovascular risk factors, particularly blood pressure and blood lipids, has been examined in detail in a large prospective study of 7735 middle-aged men drawn from general practices in 24 British towns. The analyses are restricted to the 5494 men free of any evidence of ischaemic heart disease at screening.Smoking, body mass index, physical activity, alcohol intake and lung function (FEV1) were factors strongly associated with haematocrit levels independent of each other. Age showed a significant but small independent association with haematocrit. Non-manual workers had slightly higher haematocrit levels than manual workers; this difference increased considerably and became significant after adjustment for the other risk factors. Diabetics showed significantly lower levels of haematocrit than non-diabetics. In the univariate analysis, haematocrit was significantly associated with total serum protein (r = 0*18), cholesterol (r = 0.16), triglyceride (r = 0.15), diastolic blood pressure (r = 0.17) and heart rate (r = 0.14); all at p <0.0001. A weaker but significant association was seen with systolic blood pressure (r = 0.09, p <0.001). These relationships remained significant even after adjustment for age, smoking, body mass index, physical activity, alcohol intake, lung function, presence of diabetes, social class and for each of the other biological variables; the relationship with systolic blood pressure was considerably weakened. No association was seen with blood glucose and HDL-cholesterol. This study has shown significant associations between several lifestyle characteristics and the haematocrit and supports the findings of a significant relationship between the haematocrit and blood lipids and blood pressure. It emphasises the role of the haematocrit in assessing the risk of ischaemic heart disease and stroke in individuals, and the need to take haematocrit levels into account in determining the importance of other cardiovascular risk factors.

The Relation of Body Mass Index to Biochemical Parameters and Profile of Heart Failure

2018 ◽  
Vol 69 (7) ◽  
pp. 1673-1677
Author(s):  
Viviana Aursulesei ◽  
Andrei Manta ◽  
Razan Al Namat ◽  
Monica Hugianu ◽  
Angela Maria Moloce ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Body Mass Index ◽  
Body Mass ◽  
Patient Selection ◽  
Biochemical Parameters ◽  
Obesity Paradox ◽  
Lipid Levels ◽  
Randomized Control ◽  
Selection Parameters

The bidirectional relation between body mass index (BMI) and heart failure (HF) is complex and not fully understood. The obesity paradox phenomena is controversial and related to patient selection, parameters used for defining abnormal weight, characteristics of HF. Our study sustain the importance of controlling risk factors, in particular plasma glucose, lipid levels, as well as hypertension in patients with HF and BMI over 25 kg/m2. Also, in contrast to the randomized control studies our results can only partially support data related to obesity paradox phenomena.

scholarly journals The role of physical activity on cardiovascular risk factors in adolescents

2010 ◽  
Vol 50 (4) ◽  
pp. 220
Author(s):  
Nadia Dwi Insani ◽  
Sukman Tulus Putra ◽  
Agus Firmansyah
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Blood Pressure ◽  
Body Mass Index ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
High Activity ◽  
Blood Lipid ◽  
Waist To Hip Ratio ◽  
Activity Group

Background Cardiovascular diseases remain the leading cause of death worldwide. Atherosclerotic process increases rapidly during adolescence. Physical activity is considered important in this period to modify cardiovascular risk factors, thus preventing disease in the future.Objective To determine whether different physical activity status in adolescence can influence body mass index (BMBMI), waist-to-hip ratio, blood pressure (BP), and blood lipid profile.Methods This was a cross-sectional descriptive study, conducted from December 2009 to January 2010. Adolescents who fulfilled the study criteria were classified into high and low physical activity category. Further examination including body mass index, waist-to-hip ratio, blood pressure, and blood lipid profile were performed.Results Adolescents with high physical activity had higher, but statistically insignificant, BMBMI compared to adolescents in the P=0.493] and significantly lower waist-to-hip ratio [0.80 (range 0.73-0.9) vs.. 0.82 (range 0.7-0.9), P=0.019]. Difference in BP was not statistically significant between both groups [diastolic BP (70 (range 60-90) mmHg vs. 70 (range 60-90) mmHg, P=0.148; systolic BP 100 (range 90-130) mmHg vs. 100 (range 90-140) mmHg, P=0.228)]. Blood lipid examination in the high activity group showed significantly higher HDL cholesterol and lower triglyceride compared to the low activity group [HDL 59.8 (SD 11.8) mg/dL vs. 54.7 (SD 8.9) mg/dL; p=0.044; triglyceride: 60 (range 32-203) mmHg vs. 82 (range 37-198) mmHg, P=0.014]. Total and LDL cholesterol [total cholesterol 169.8 (SD 28.6) mmHg vs. 181.2 (SD 30.8) mmHg, P=0.107; LDL 103.6 (SD 26.8) mmHg vs. 114.1 (SD 27.3) mmHg, P=0.100] were lower in the high activity group but not statistically different in both groups.Conclusions Adolescents with high physical activity show less cardiovascular risk factors compared to those in the low physical activity group.

scholarly journals High-intensity activity is more strongly associated with metabolic health in children compared to sedentary time: a cross-sectional study of the I.Family cohort

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Jonatan Fridolfsson ◽  
Christoph Buck ◽  
Monica Hunsberger ◽  
Joanna Baran ◽  
Fabio Lauria ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Insulin Resistance ◽  
Blood Pressure ◽  
Body Mass Index ◽  
High Density Lipoprotein ◽  
High Density Lipoprotein Cholesterol ◽  
Density Lipoprotein ◽  
Cross Sectional ◽  
Intensity Physical Activity

Abstract Background Physical activity (PA) during childhood is important for preventing future metabolic syndrome (MetS). To examine the relationship between PA and MetS in more detail, accurate measures of PA are needed. Previous studies have only utilized a small part of the information available from accelerometer measured PA. This study investigated the association between measured PA and MetS in children with a new method for data processing and analyses that enable more detailed interpretation of PA intensity level. Methods The association between PA pattern and risk factors related to MetS was investigated in a cross- sectional sample of children (n = 2592, mean age 10.9 years, 49.4% male) participating in the European multicenter I. Family study. The risk factors examined include body mass index, blood pressure, high-density lipoprotein cholesterol, insulin resistance and a combined risk factor score (MetS score). PA was measured by triaxial accelerometers and raw data was processed using the 10 Hz frequency extended method (FEM). The PA output was divided into an intensity spectrum and the association with MetS risk factors was analyzed by partial least squares regression. Results PA patterns differed between the European countries investigated, with Swedish children being most active and Italian children least active. Moderate intensity physical activity was associated with lower insulin resistance (R2 = 2.8%), while vigorous intensity physical activity was associated with lower body mass index (R2 = 3.6%), MetS score (R2 = 3.1%) and higher high-density lipoprotein cholesterol (R2 = 2.3%). PA of all intensities was associated with lower systolic- and diastolic blood pressure, although the associations were weaker than for the other risk factors (R2 = 1.5% and R2 = 1.4%). However, the multivariate analysis implies that the entire PA pattern must be considered. The main difference in PA was observed between normal weight and overweight children. Conclusions The present study suggests a greater importance of more PA corresponding to an intensity of at least brisk walking with inclusion of high-intense exercise, rather than a limited time spent sedentary, in the association to metabolic health in children. The methods of data processing and statistical analysis enabled accurate analysis and interpretation of the health benefits of high intensity PA that have not been shown previously.

Association between maternal prepregnancy body mass index with offspring cardiometabolic risk factors: analysis of three Brazilian birth cohorts

2021 ◽  
pp. 1-7
Author(s):  
Mariane da Silva Dias ◽  
Alicia Matijasevich ◽  
Ana Maria B. Menezes ◽  
Fernando C. Barros ◽  
Fernando C. Wehrmeister ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Body Mass Index ◽  
Diastolic Blood Pressure ◽  
Cardiometabolic Risk ◽  
Hdl Cholesterol ◽  
Cardiometabolic Risk Factors ◽  
Birth Cohorts ◽  
Prepregnancy Bmi ◽  
Prepregnancy Body Mass Index

Abstract Evidence suggests that maternal prepregnancy body mass index (BMI) is associated with offspring cardiometabolic risk factors. This study was aimed at assessing the association of maternal prepregnancy BMI with offspring cardiometabolic risk factors in adolescence and adulthood. We also evaluated whether offspring BMI was a mediator in this association. The study included mother–offspring pairs from three Pelotas birth cohorts. Offspring cardiometabolic risk factors were collected in the last follow-up of each cohort [mean age (in years) 30.2, 22.6, 10.9]. Blood pressure was measured using an automatic device, cholesterol by using an enzymatic colorimetric method, and glucose from fingertip blood, using a portable glucose meter. In a pooled analysis of the cohorts, multiple linear regression was used to control for confounding. Mediation analysis was conducted using G-computation formula. In the adjusted model, mean systolic blood pressure of offspring from overweight and obese mothers was on average 1.25 (95% CI: 0.45; 2.05) and 2.13 (95% CI: 0.66; 3.59) mmHg higher than that of offspring from normal-weight mothers; for diastolic blood pressure, the means were 0.80 (95% CI: 0.26; 1.34) and 2.60 (95% CI: 1.62; 3.59) mmHg higher, respectively. Non-HDL cholesterol was positively associated with maternal BMI, whereas blood glucose was not associated. Mediation analyses showed that offspring BMI explained completely the association of maternal prepregnancy BMI with offspring systolic and diastolic blood pressure, and non-HDL cholesterol. Our findings suggest that maternal prepregnancy BMI is positively associated with offspring blood pressure, and blood lipids, and this association is explained by offspring BMI.

Genetic analysis of serum lipid levels and blood pressure in a large kindred

1987 ◽  
Vol 26 (3) ◽  
pp. 511-519 ◽  
Author(s):  
Mary L. Marazita ◽  
Robert C. Elston ◽  
Kadambari K. Namboodiri ◽  
Curtis G. Hames ◽  
John M. Opitz ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Genetic Analysis ◽  
Serum Lipid ◽  
Lipid Levels ◽  
Serum Lipid Levels
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