The effects of aquatic therapy on mobility of individuals with neurological diseases: a systematic review

2014 ◽  
Vol 29 (8) ◽  
pp. 741-751 ◽  
Author(s):  
Andresa R Marinho-Buzelli ◽  
Alison M Bonnyman ◽  
Mary C Verrier
Keyword(s):  
Randomized Controlled Trials ◽  
Gait Speed ◽  
Neurological Diseases ◽  
Dynamic Balance ◽  
Experimental Studies ◽  
Controlled Trials ◽  
Aquatic Therapy ◽  
Randomized Controlled ◽  
Randomized Studies ◽  
Before And After

Objective:To summarize evidence on the effects of aquatic therapy on mobility in individuals with neurological diseases.Data sources:MEDLINE, EMBASE, PsycInfo, CENTRAL, CINAHL, SPORTDiscus, PEDro, PsycBITE and OT Seeker were searched from inception to 15 September 2014. Hand-searching of reference lists was performed in the selected studies.Review methods:The search included randomized controlled trials and quasi-experimental studies that investigated the use of aquatic therapy and its effect on mobility of adults with neurological diseases. One reviewer screened titles and abstracts of retrieved studies from the search strategy. Two reviewers independently examined the full texts and conducted the study selection, data extraction and quality assessment. A narrative synthesis of data was applied to summarize information from included studies. The Downs and Black Scale was used to assess methodological quality.Results:A total of 116 articles were obtained for full text eligibility. Twenty studies met the specified inclusion criteria: four Randomized Controlled Trials (RCTs), four non-randomized studies and 12 before-and-after tests. Two RCTs (30 patients with stroke in the aquatic therapy groups), three non-randomized studies and three before-and-after studies showed “fair” evidence that aquatic therapy increases dynamic balance in participants with some neurological disorders. One RCT (seven patients with stroke in the aquatic therapy group) and two before-and-after tests (20 patients with multiple sclerosis) demonstrated “fair” evidence on improvement of gait speed after aquatic therapy.Conclusion:Our synthesis showed “fair” evidence supporting the use of aquatic therapy to improve dynamic balance and gait speed in adults with certain neurological conditions.

scholarly journals Improving Cardiovascular Health through Nudging Healthier Food Choices: A Systematic Review

Nutrients ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 2520 ◽  
Author(s):  
Christine Tørris ◽  
Hilde Mobekk
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Dietary Habits ◽  
Negative Impact ◽  
Experimental Studies ◽  
Food Choices ◽  
Overweight And Obesity ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
The Impact

Obesity and metabolic syndrome are considered major public health problems, and their negative impact on cardiovascular disease (CVD) and diabetes mellitus type 2 (DM2) is profound. Targeting modifiable risk factors such as dietary habits is therefore of great importance. Many of today’s health challenges with overweight and obesity may have behavioral roots, and traditional methods such as regulations and campaigns are often insufficient to improve dietary choices. Nudging or choice architecture might be a viable tool to influence people’s everyday choices and behaviors to better outcomes. This paper reviews the current state of the rapidly expanding number of experimental field studies that investigate the effects/associations of nudging on healthy food choices. A systematic literature search was conducted in PubMed, where 142 citations were identified. Based on selection criteria, six randomized controlled trials and 15 non-randomized controlled trials were ultimately included. The results of this systematic review show that many of the studies included traffic-light labeling, which may be a promising strategy. The reviewed findings, however, also highlight the challenges that confront experimental studies examining the impact of nudging on diet.

The Impact of ARC in Human Service Organizations

2018 ◽  
Author(s):  
Anthony L. Hemmelgarn ◽  
Charles Glisson
Keyword(s):  
Randomized Controlled Trials ◽  
Experimental Studies ◽  
Empirical Support ◽  
Controlled Trials ◽  
Evidence Based ◽  
Client Outcomes ◽  
Service Effectiveness ◽  
Randomized Controlled ◽  
Arc Model ◽  
The Impact

This chapter describes empirical support for the ARC model from multiple randomized controlled trials. These trials describe the effects of ARC on organizational culture and climate, organizational priorities, clinicians’ work attitudes, clinicians’ evidence-based practice behaviors, and most importantly, client outcomes. Both the ARC model and the validity of the OSC measurement system are also supported by a number of non-experimental and quasi-experimental studies. Collectively, these studies describe linkages with OSC and related criteria using regional and nationwide samples that are fundamental to explaining the value of the ARC model. Much of this work is referenced throughout the book. In this chapter, the authors focus on the randomized controlled trials to support causal inferences about the effects of ARC, including impact on client outcomes, staff outcomes such as turnover and engagement, as well as impact on evidence-based practices. The evidence also highlights the implications for using ARC strategies in planned efforts to improve service effectiveness.

scholarly journals Reporting Quality of Journal Abstracts for Surgical Randomized Controlled Trials Before and After the Implementation of the CONSORT Extension for Abstracts

2019 ◽  
Vol 43 (10) ◽  
pp. 2371-2378 ◽  
Author(s):  
Benjamin Speich ◽  
Kimberly A. Mc Cord ◽  
Arnav Agarwal ◽  
Viktoria Gloy ◽  
Dmitry Gryaznov ◽  
...  
Keyword(s):  
Randomized Controlled Trials ◽  
Reporting Quality ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Before And After

scholarly journals Perspectives on the Use of Ninjin’yoeito in Modern Medicine: A Review of Randomized Controlled Trials

2019 ◽  
Vol 2019 ◽  
pp. 1-15 ◽  
Author(s):  
Shin Takayama ◽  
Ryutaro Arita ◽  
Minoru Ohsawa ◽  
Akiko Kikuchi ◽  
Hiromichi Yasui ◽  
...  
Keyword(s):  
Side Effects ◽  
Randomized Controlled Trials ◽  
Western Medicine ◽  
Case Reports ◽  
Experimental Studies ◽  
Kampo Medicine ◽  
Cochrane Library ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Medicinal Treatment

Background. Ninjin’yoeito (NYT), a traditional Japanese (Kampo) medicine that originates from China, has been used to treat qi and blood deficiency based on its original concept. Kampo medicine has been widely used to treat many conditions and disorders combined with western medicine or Kampo medicine alone in modern situation. Aims. We reviewed randomized controlled trials (RCTs) of NYT and discussed various standpoints regarding its use in modern situation. Methods. We searched PubMed, Cochrane Library, and Evidence Reports of Kampo Treatment (EKAT) for articles written in English, and Ichushi, J-Stage, and EKAT for those written in Japanese. Articles published before January 1, 2019, were retrieved using the keywords “ninjinyoeito” and “ninjin’yoeito,” and RCTs were selected from these extracted articles. Result. Of 734 articles, 13 were RCTs, 46 were non-RCTs or studies of other designs, 15 were case reports, and 36 were experimental studies using NYT. NYT was evaluated for its use as a treatment for cancer and related conditions, refractory blood diseases and conditions, and otorhinolaryngologic symptom in 13 RCTs. Based on the use of Kampo medicine in modern situation called as Yasui’s classification, 10 of 13 RCTs were categorized as “the side effects of Western medicinal treatment are mitigated when combined with Kampo treatment” and the remaining 3 were categorized as “treatment effect of Kampo medicine is increased in combination with standard Western medicinal treatment.” Conclusion. Several studies demonstrated the efficacy of NYT in refractory diseases and other conditions, and the accompanied side effects of treatment with western medicine.

Effects of Probiotics on Diabetic Nephropathy: A Systematic Review

2020 ◽  
Vol 15 (3) ◽  
pp. 234-242 ◽  
Author(s):  
Eugenia Vlachou ◽  
Anastasia Ntikoudi ◽  
Ourania Govina ◽  
Maria Lavdaniti ◽  
Nikolaos Kotsalas ◽  
...  
Keyword(s):  
Systematic Review ◽  
Diabetic Nephropathy ◽  
Adverse Events ◽  
Randomized Controlled Trials ◽  
Positive Impact ◽  
Experimental Studies ◽  
Controlled Trials ◽  
Extensive Literature ◽  
Probiotic Supplementation ◽  
Randomized Controlled

Background: Diabetic Nephropathy is a frequent complication of diabetes mellitus due to functional and structural modifications in multiple kidney compartments. Probiotics have risen lately as a forthcoming therapeutic intervention but they have not been systematically evaluated in diabetic nephropathy so far. The aim of this systematic review was to evaluate randomized controlled trials and experimental studies assessing the effect of probiotic supplements on diabetic nephropathy. Methods: An extensive literature search was conducted through electronic databases (PubMed, Scopus, Cinahl and Medline) with the Medical Subject Headings and entry terms of “diabetic nephropathy”, “diabetic renal disease” and “probiotics”. The search yielded 116 results, 9 of which met the inclusion criteria for this systematic review. Results: Most of the microorganisms used in the studies belonged to the Lactobacillus and Bifidobacterium genus. The dosage ranged from 2×107 to 6×1010 CFU/ g. The form of the probiotics varied across the studies (capsules, sachets, soy milk, kefir and honey). The majority of the studies demonstrated the benefits of probiotic supplementation on the reduction of inflammation, oxidative stress and on the amelioration of renal function biomarkers in subjects with diabetic nephropathy. No major gastrointestinal adverse events were observed during the intervention time with probiotics. Conclusion: : Findings of this systematic review demonstrate the positive impact of probiotics on Diabetic Nephropathy without any major adverse events. Moreover, future larger randomized controlled trials with bigger samples and longer follow-up time are deemed necessary for further valid results on the effectiveness of probiotic supplementation on Diabetic Nephropathy.

scholarly journals The Effect of Inflammation and Insulin Resistance on Lipid and Lipoprotein Responsiveness to Dietary Intervention

2020 ◽  
Vol 4 (11) ◽  
Author(s):  
Kristina S Petersen ◽  
Kate J Bowen ◽  
Alyssa M Tindall ◽  
Valerie K Sullivan ◽  
Emily A Johnston ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Randomized Controlled Trials ◽  
Dietary Intervention ◽  
Fatty Acid Biosynthesis ◽  
Experimental Studies ◽  
Controlled Trials ◽  
Low Grade ◽  
Cvd Risk ◽  
Randomized Controlled ◽  
Low Grade Inflammation

ABSTRACT Lipids and lipoproteins are major targets for cardiovascular disease (CVD) prevention. Findings from a limited number of clinical trials suggest diet-induced atherogenic lipoprotein lowering can be altered in the presence of chronic low-grade inflammation or insulin resistance. This review summarizes results from randomized controlled trials that have examined diet-induced changes in lipids/lipoproteins by inflammatory or insulin sensitivity status. In addition, mechanisms to explain these clinical observations are explored. Post hoc analyses of data from a limited number of randomized controlled trials suggest attenuation of diet-induced lipid/lipoprotein lowering in individuals with inflammation and/or insulin resistance. These findings are supported by experimental studies showing that inflammatory stimuli and hyperinsulinemia alter genes involved in endogenous cholesterol synthesis and cholesterol uptake, reduce cholesterol efflux, and increase fatty acid biosynthesis. Further a priori defined research is required to better characterize how chronic low-grade inflammation and insulin resistance modulate lipid and lipoprotein responsiveness to guide CVD risk reduction in individuals presenting with these phenotypes.

scholarly journals Assessing the impact of retraction on the citation of randomized controlled trial reports: an interrupted time-series analysis

2018 ◽  
Vol 24 (1) ◽  
pp. 44-51 ◽  
Author(s):  
Andrew Mott ◽  
Caroline Fairhurst ◽  
David Torgerson
Keyword(s):  
Time Series ◽  
Randomized Controlled Trial ◽  
Randomized Controlled Trials ◽  
Controlled Trial ◽  
Interrupted Time Series ◽  
Controlled Trials ◽  
Interrupted Time Series Analysis ◽  
Randomized Controlled ◽  
Before And After ◽  
The Impact

Objectives To assess the impact of retraction on the citation of randomized controlled trials. Methods We used an interrupted time-series with matched controls. PubMed, CINHAL, Google and the Retraction Watch Database were searched. We identified retracted publications reporting the results of randomized controlled trials involving human participants with two years of available data before and after retraction. We obtained monthly citation counts across all articles for the 24 months before and after retraction, from Web of Science. We used a Poisson segmented regression to detect changes in the level and trend of citation following retraction. We also undertook a matched control analysis of unretracted randomized controlled trials and a sensitivity analysis to account for cases of large-scale, well-advertised fraud. Results We identified 387 retracted randomized controlled trial reports, of which 218 (56.3%) were included in the interrupted time-series analysis. A reduction of 22.9% (95% CI 4.0% to 38.2%, p = 0.02) was observed in the number of citations in the month after retraction, and a further reduction of 1.9% (95% CI 0.4% to 3.5%, p = 0.02) per month in the following 24 months, relative to the expected trend. There was no evidence of a statistically significant reduction among the matched controls. Authors with a large number of retractions saw a 48.2% reduction at the time of retraction (95% CI 17.7% to 67.3%, p = 0.01). Other cases had a more gradual reduction with no change at the time of retraction and a 1.8% reduction per month in the following 24 months (95% CI 0.2% to 3.4%, p = 0.03). Conclusions Retractions of randomized controlled trial reports can be effective in reducing citations. Other factors, such as the scale of the retractions and media attention, may play a role in the effectiveness of the reduction.

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