scholarly journals Relationship between enuresis and obstructive sleep apnea–hypopnea syndrome in children

2020 ◽  
Vol 48 (12) ◽  
pp. 030006052097740
Author(s):  
Chen Sun ◽  
Yingpeng Xu ◽  
Chenxi Luo ◽  
Qi Li
Keyword(s):  
Risk Factors ◽  
Obstructive Sleep Apnea ◽  
Logistic Regression ◽  
Sleep Apnea ◽  
Pearson Correlation ◽  
Apnea Hypopnea Index ◽  
Chi Square ◽  
Obstructive Sleep ◽  
Chi Square Test ◽  
Hypopnea Syndrome

Objective We explored the relationship between enuresis and obstructive sleep apnea–hypopnea syndrome (OSAHS) in children and influencing factors of enuresis with OSAHS. Methods We recruited 196 children ≥5 years old from the otolaryngology outpatient department, who experienced snoring and underwent nasopharynx lateral radiography and in-laboratory polysomnography. We analyzed correlations between the apnea–hypopnea index (AHI) and lowest oxygen saturation (L-SaO2) with age, body mass index (BMI), tonsil size, and adenoidal–nasopharyngeal (A/N) ratio using the Pearson correlation test. Differences in severe OSAHS prevalence, age, AHI, L-SaO2, tonsil size, and A/N ratio between children with and without enuresis were assessed using the chi-square test and t-test. Risk factors of enuresis were analyzed using logistic regression. Follow-up was conducted to assess remission in children with enuresis after adenotonsillectomy. Results BMI, tonsil size, and A/N ratio were correlated with AHI and L-SaO2. Severe OSAHS prevalence, AHI, tonsil size, and A/N ratio were higher and L-SaO2 were lower in children with enuresis. Logistic regression showed that BMI, AHI, tonsil size, and sleep apnea were risk factors for enuresis. Conclusions Our study findings showed that enuresis was associated with OSAHS in children. Adenotonsillectomy may improve the symptoms of enuresis.

scholarly journals Obstructive Sleep Apnea Syndrome (OSAS) Decrease Concentration Levels in Young Adults

2020 ◽  
Vol 1 (2) ◽  
pp. 17-20
Author(s):  
Fidela Hanan Zivana
Keyword(s):  
Obstructive Sleep Apnea ◽  
Young Adults ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Concentration Level ◽  
Sleep Apnea Syndrome ◽  
Chi Square ◽  
Obstructive Sleep ◽  
Chi Square Test ◽  
Apnea Syndrome

Background: Obstructive Sleep Apnea Syndrome (OSAS) is sleeping-disorder that’s characterized by recurrent episodes of upper airway obstruction during sleep. Fourteen percent of world populations suffer from OSAS. OSA patients are 7,5 to 20 times more likely to have difficulties with concentration, learning new tasks, and execution of monotonous tasks.Objective: The primary objective of this study was to investigate the relationship between Obstructive Sleep Apnea Syndrome (OSAS) and concentration level in young adults.Methods: This is an analytic observational study with cross-sectional design. Sampling was carried out with total sampling. Samples that qualified the inclusion and exclusion criteria were assessed by OSAS using the Epworth Sleepiness Scale (ESS)  questionnaire and Digit Symbol Substitution Test was used to assess the concentration level. The data were analyzed, using the chi-square test and the prevalence (PR) test.Results: The Chi-square test showed that there was a significant relationship between OSAS and concentration level (p=0.033). The Prevalence Ratio test found that OSAS decreased concentration level by 1,55 compared to not OSAS.Conclusion:  There was a significant relationship between OSAS and concentration level in young adults. OSAS patients are 1,55 more likely to have a decrease concentration level when compared with healthy individuals.

Abstract TMP55: Polysomnographic and Sleep-related Variables Associated to Leukoaraiosis in Patients with Obstructive Sleep Apnea

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Kevin R Duque ◽  
Brian Villafuerte ◽  
Fiorella Adrianzen ◽  
Rodrigo Zamudio ◽  
Andrea Mendiola ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Logistic Regression ◽  
Sleep Apnea ◽  
Multinomial Logistic Regression ◽  
Sleep Time ◽  
Cross Sectional Study ◽  
Apnea Hypopnea Index ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
Medical Histories

Introduction: Obstructive sleep apnea (OSA) is a biological plausible risk factor for leukoaraiosis (LA). We tested the hypothesis that polysomnographic (PSG) and sleep-related variables are associated to LA in OSA patients. Methods: Cross-sectional study in which PSG records, medical histories and brain 1.5T MRI were collected from all consecutive patients who had attended a Sleep Medicine Center between 2009-2014. LA was graded from 0 to 9 with the ’Atherosclerosis Risk In Communities’ study scale. OSA was defined by The International Classification of Sleep Disorders, 2014, and its severity categorizing according to apnea-hypopnea index (AHI, <15 mild, 15 to <30 moderate, 30 to <45 severe and ≥45 very severe). A multinomial logistic regression was performed to describe the association between OSA severity and LA (divided into 2 groups: mild-to-moderate LA and non-to-minimal LA). The covariates for all regression models were age, gender, BMI, hypertension, ischemic stroke, myocardial infarction, diabetes and pack-year of smoking. Results: From 82 OSA patients (77% male; mean age 58±9 years, range 19-91), 54 (66%) had LA. Mild-to-moderate LA was found in 13 patients (8 mild and 5 moderate LA) and non-to-minimal LA in 69 (41 minimal and 28 non LA). Spearman’s correlation coefficient between AHI and LA grade was 0.41 (p<0.001). Furthermore, the higher OSA severity, the higher LA severity (p<0.001, for Jonckheere-Terpstra test for ordered alternatives). In the multinomial logistic regression model adjusted for cofounders, severe OSA patients had higher risk for mild or moderate LA (HR 12.8, 95% IC 1.2-141) compared to mild-to-moderate OSA patients. Additionally, self-reported habitual sleep duration from 7 to 9 hours (HR 0.36, 90% IC 0.14-0.90) and proportion of time in apnea/hypopnea over total sleep time (HR 1.04 for one unit increase, 90% IC 1.01-1.08) could be associated with the presence of LA (adjusted only for age and gender). In a multiple regression analysis with all the aforementioned variables, age (p=0.002), diabetes (p=0.003), and OSA severity (p=0.04) were predictors of the presence of LA. Conclusion: Patients with severe OSA had higher risk for mild to moderate LA when compared to patients with mild or moderate OSA.

scholarly journals Obstructive Sleep Apnea as a Predictor of Abnormal Heart Rate Turbulence

2019 ◽  
Vol 9 (1) ◽  
pp. 1 ◽  
Author(s):  
Dominika Urbanik ◽  
Paweł Gać ◽  
Helena Martynowicz ◽  
Małgorzata Poręba ◽  
Maciej Podgórski ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Rate ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Holter Monitoring ◽  
Older Age ◽  
Apnea Hypopnea Index ◽  
Heart Rate Turbulence ◽  
Obstructive Sleep ◽  
Independent Risk Factors

Obstructive sleep apnea (OSA) causes dysfunction of the autonomic nervous system, but the exact mechanism has not been fully understood. The aim of this study was to analyse the relationship between the incidence and severity of OSA and heart rate turbulence (HRT). Seventy one patients with clinical suspicion of OSA were qualified to participate in the study. All participants took part in a survey and were subjected to laboratory tests, 24-hour electrocardiogram (ECG) Holter monitoring with HRT analysis and polysomnography. The group with OSA manifested significantly higher turbulence onset (TO) and lower turbulence slope (TS) as compared to the group without OSA. Older age, diabetes, hypertension and higher apnea/hypopnea index (AHI) were found to be independent risk factors for increased TO, whereas older age, higher body mass index (BMI), higher blood glucose levels, hypertension and higher AHI were independent risk factors for TS reduction. The AHI ≥65 criterion indicates abnormal HRT in patients with OSA with 94.9% sensitivity and 50.0% specificity, which gives a prediction accuracy of 85.7%. In summary, OSA should be considered as a predictor of abnormal HRT.

Predictors of Surgical Outcomes of Uvulopalatopharyngoplasty for Obstructive Sleep Apnea Hypopnea Syndrome

2011 ◽  
Vol 145 (6) ◽  
pp. 1049-1054 ◽  
Author(s):  
Yuan Ping Xiong ◽  
Hong Liang Yi ◽  
Shan Kai Yin ◽  
Li Li Meng ◽  
Xu Lan Tang ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Lipid Metabolism ◽  
Sleep Apnea ◽  
Oxygen Saturation ◽  
Success Rate ◽  
Surgical Outcomes ◽  
Apnea Hypopnea Index ◽  
Glucose And Lipid Metabolism ◽  
Obstructive Sleep ◽  
Hypopnea Syndrome

Objectives. To investigate predictors of surgical outcomes of uvulopalatopharyngoplasty (UPPP) for obstructive sleep apnea hypopnea syndrome (OSAHS). Study Design. Case series with planned data collection. Setting. A university medical center. Subjects and Methods. Thirty-nine patients with OSAHS received Z-palatopharyngoplasty (ZPPP) or Han-uvulopalatopharyngoplasty (H-UPPP). All patients were evaluated within 3 months before surgery and at 6 to 12 months after surgery. Statistical analyses were conducted on preoperative parameters that could have affected surgical efficacy and outcome. Success was defined as an apnea–hypopnea index (AHI) fewer than 20 times per hour and a decrease of more than 50%. Results. The success rate was 56.4% (22/39 patients). There were statistically significant differences in AHI, lowest oxygen saturation (L-Sao2), time with oxygen saturation less than 90% (CT90), percentage of time with oxygen saturation less than 90% (CT90%), microarousal index (MI), apolipoprotein E (ApoE), high-density lipoprotein (HDL), fasting blood glucose (FBG), and Friedman OSA stage between the treatment success and failure groups. Higher success rate was predicted by lower severity, as indicated by lower AHI, CT90, CT90%, and MI; higher L-Sao2; and fewer glucose and lipid metabolism abnormalities, shown by lower ApoE and FBG and higher HDL. Conclusions. Disease severity, glucose and lipid metabolism, and Friedman OSA stage may be important predictors of surgical outcome of UPPP for OSAHS.

scholarly journals Association between neck circumference and the severity of obstructive sleep apnea

2020 ◽  
Author(s):  
Shah Ibrahim Mohd Irman ◽  
Mohamad Hazama ◽  
Mohamad Amran ◽  
Mohamad Irfan
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Pearson Correlation ◽  
Local Population ◽  
Multiple Linear Regression Model ◽  
Mean Value ◽  
Neck Circumference ◽  
Apnea Hypopnea Index ◽  
Obstructive Sleep ◽  
Tertiary Center

Introduction: Neck circumference (NC) is one of the parameters to be associated with obstructive sleep apnea (OSA). However, there is lack of research data reflecting our local population with regard to the size of NC in relation to the severity of OSA. Aim: The primary goal of this study was to investigate the association of NC with OSA and to compare NC with other parameters as a predictor of the severity of OSA, among local population. This future reliable parameter can be used in front line clinics as to guide the referral to the tertiary center. Material and methods: This was a prospective study conducted upon 120 OSA patients, aged within 18–55 years, who underwent overnight polysomnography with apnea/hypopnea index more than 5 and met all the inclusion criteria. All patients completed the Epworth sleepiness scale questionnaire while all the parameter measurement including height, weight, body mass index and NC were documented. Results and discussion: A Pearson correlation analysis showed NC was significantly associated with OSA (r = 0.495, P < 0.001) while multiple linear regression model displayed an association between NC and lowest SpO2 desaturation during sleep (LSAT) as predictors of OSA severity (P < 0.001). Mean value of NC also significantly higher among severe OSA compared to mild OSA (42.7 ± 0.9 cm vs. 39.0 ± 1.3 cm; P < 0.001). Conclusions: NC was significantly associated with OSA and both NC and LSAT were significantly correlated as predictors of OSA severity.

scholarly journals Uvulopalatopharyngoplasty and barbed reposition pharyngoplasty with and without hyoid suspension for obstructive sleep apnea hypopnea syndrome: A comparison of long-term functional results

2020 ◽  
Author(s):  
Antonio Minni ◽  
Fabrizio Cialente ◽  
Massimo Ralli ◽  
Andrea Colizza ◽  
Quirino Lai ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Protective Factor ◽  
Surgical Techniques ◽  
Functional Results ◽  
Apnea Hypopnea Index ◽  
Obstructive Sleep ◽  
Hyoid Suspension ◽  
Hypopnea Syndrome

Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common condition; when conservative approaches are not effective, surgical techniques aimed at reducing the airway obstruction effect are used. This retrospective study aimed at comparing the functional outcomes in patients with OSAHS undergoing uvulopalatopharyngoplasty (UPPP) according to Fairbanks and barbed reposition pharyngoplasty (BRP) according to Mantovani, with or without hyoid suspension (HS). One-hundred twenty-two consecutive OSAHS patients who underwent surgical treatment were included in the study. Patients were divided into 4 groups; all patients underwent preoperative and postoperative polysomnography (PSG) with apnea/hypopnea index (AHI) and oxygen desaturation index (ODI) evaluation, and Epworth Sleepiness Scale (ESS) evaluation. The results were analyzed according to the different surgical procedures, in relation to the preoperative PSG and anthropometric data. A significant reduction was observed at 18-month follow-up for patients in BRP group for BMI (p = 0.004), ESS (p < 0.0001), ODI (p < 0.0001), and AHI (p < 0.0001). Risk factors for poor postoperative AHI reduction were evaluated; preoperative AHI was the strongest independent protective factor, while preoperative ODI was the strongest risk factor. The association of HS with UPPP or BRP showed significant results in terms of higher postoperative AHI reduction only when associated to UPPP (p < 0.0001). This study showed that the BRP technique was more effective compared to UPPP for patients with OSAHS. The association of HS showed greater benefits in UPPP compared to BRP.  Randomized prospective trials with longer follow-up are necessary to confirm our results and formulate a more accurate indication of the optimal therapeutic strategy.

scholarly journals Application of IoT-based medical diagnosis and treatment in patients with obstructive sleep apnea/hypopnea syndrome in primary hospitals: A preliminary study

2018 ◽  
Vol 01 (03) ◽  
pp. 207-212
Author(s):  
Yuhua Wu ◽  
Jian Zhou ◽  
Jing Li ◽  
Jie Liu ◽  
Shanqun Li ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Medical Technology ◽  
Diagnosis And Treatment ◽  
Apnea Hypopnea Index ◽  
Medical Monitoring ◽  
Obstructive Sleep ◽  
Before And After ◽  
Preliminary Study ◽  
Hypopnea Syndrome

Objective: To conduct a preliminary study of the hierarchical diagnosis and treatment of patients with obstructive sleep apnea/hypopnea syndrome (OSAHS) using the Internet of Things (IoT) medical technology and to explore the feasibility of the hierarchical diagnosis, treatment, and management of OSAHS patients using IoT medicine in primary hospitals. Methods: The IoT technology and a remote medical monitoring system were used to observe and compare the respiratory and sleep parameters before and after a three-month intervention in 47 patients with OSAHS who met the diagnostic criteria and were selected in the Kashgar region. All parameters were compared based on the severity (mild, moderate, and severe) of OSAHS. Results: The Epworth Sleepiness Scale (ESS) score, apnea–hypopnea index (AHI), and nighttime minimum oxygen saturation (lowest SaO2min) improved in patients with OSAHS from before to after treatment ([Formula: see text]). The improvements were more profound in OSAHS patients with cardiovascular disease such as hypertension. Conclusion: The IoT medical technology can help to hierarchically diagnose, treat, and manage patients with OSAHS. It is feasible for primary hospitals in rural regions to use the IoT technology for the hierarchical diagnosis and treatment of OSAHS patients.

scholarly journals Risk factors for respiratory complications after adenotonsillectomy in children with obstructive sleep apnea

2015 ◽  
Vol 41 (3) ◽  
pp. 238-245 ◽  
Author(s):  
Renato Oliveira Martins ◽  
Nuria Castello-Branco ◽  
Jefferson Luis de Barros ◽  
Silke Anna Theresa Weber
Keyword(s):  
Risk Factors ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Teaching Hospital ◽  
Orotracheal Intubation ◽  
Apnea Hypopnea Index ◽  
Respiratory Complications ◽  
Cross Sectional ◽  
Historical Cohort ◽  
Obstructive Sleep

Objective: To identify risk factors for respiratory complications after adenotonsillectomy in children ≤ 12 years of age with obstructive sleep apnea who were referred to the pediatric ICU (PICU). Methods: A cross-sectional historical cohort study analyzing 53 children after adenotonsillectomy who met predetermined criteria for PICU referral in a tertiary level teaching hospital. The Student's t-test, Mann-Whitney test, and chi-square test were used to identify risk factors. Results: Of the 805 children undergoing adenotonsillectomy between January of 2006 and December of 2012 in the teaching hospital, 53 were referred to the PICU. Twenty-one children (2.6% of all those undergoing adenotonsillectomy and 39.6% of those who were referred to the PICU) had respiratory complications. Of those 21, 12 were male. The mean age was 5.3 ± 2.6 years. A high apnea-hypopnea index (AHI; p = 0.0269), a high oxygen desaturation index (ODI; p = 0.0082), a low SpO2 nadir (p = 0.0055), prolonged orotracheal intubation (p = 0.0011), and rhinitis (p = 0.0426) were found to be independent predictors of respiratory complications. Some of the complications observed were minor (SpO2 90-80%), whereas others were major (SpO2 ≤ 80%, laryngospasm, bronchospasm, acute pulmonary edema, pneumonia, and apnea). Conclusions: Among children up to 12 years of age with OSA, those who have a high AHI, a high ODI, a low SpO2 nadir, or rhinitis are more likely to develop respiratory complications after adenotonsillectomy than are those without such characteristics.

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