scholarly journals Blood pressure and cognitive function among older adults in India

2022 ◽  
Vol 50 (1) ◽  
pp. 030006052110687
Author(s):  
Madeline R. Farron ◽  
Mohammed U. Kabeto ◽  
Deborah A. Levine ◽  
Caroline R. Wixom ◽  
Kenneth M. Langa

Objective We aimed to investigate the relationship between blood pressure and cognitive function among older adults in India. Methods In this study, we analyzed cross-sectional data of systolic and diastolic blood pressure (SBP and DBP, respectively) and cognitive testing from 3690 adults aged 60 years and older participating in the Longitudinal Aging Study in India—Diagnostic Assessment of Dementia from 14 states in India. Results After controlling for key sociodemographic, health, and geographic factors, higher SBP and lower DBP were each independently associated with worse cognitive function. Older age, female sex, lower education level, being widowed, residing in a rural area, being a member of a Scheduled Caste or Scheduled Tribe, having a low level of economic consumption, being underweight, and a history of stroke were all independently associated with worse cognitive function scores. Conclusions Both SBP and DBP were independently associated with cognitive function among older adults in India in diverging directions. Clinical interventions targeting high SBP and low DBP may benefit both cognitive health and cardiovascular health.

Circulation ◽  
2015 ◽  
Vol 131 (suppl_1) ◽  
Author(s):  
Bo Qin ◽  
Anthony J Viera ◽  
Linda S Adair ◽  
Brenda L Plassman ◽  
Lloyd J Edwards ◽  
...  

Introduction: Recent studies suggest higher visit-to-visit variability of blood pressure (BP) is associated with worse cognitive function, but evidence based on longitudinal cognitive testing has not been reported. Hypothesis: We assessed the hypothesis that higher visit-to-visit variability in BP, but not mean BP, would be associated with faster decline in cognitive function among community-dwelling older adults. Methods: This prospective cohort study comprised 1213 adults who had two or more waves of BP measurements as part of the China Health and Nutrition Survey from 1991, up to their first cognitive tests, and completed a cognitive screening test at two or more waves in 1997, 2000 or 2004. Mean (SD) age at first cognitive test was 64 (6) y. Outcomes were repeated measures of global cognitive scores (baseline mean ± SD: 19 ± 6 points), standardized composite cognitive and verbal memory scores (standardized units [SU]). Visit-to visit BP variability was expressed as the standard deviation [SD] or as the variation independent of mean (SD/mean^x, with x derived from curve fitting) in BP measures obtained at a mean interval of 3.6 years. Multivariable-adjusted linear mixed-effects models were used to determine the association of changes in cognitive scores with visit-to visit BP variability. Results: Higher visit-to-visit variability in systolic BP, but not mean systolic BP, was associated with a faster decline of cognitive function (adjusted mean difference [95% CI] for high vs. low tertile of SD in variability (Figure): global score -0.23 points/y [-0.41 to -0.04], composite scores -0.029 SU/y [-0.056 to -0.002] and verbal memory -0.044 SU/y [-0.075 to -0.012]). Higher visit-to-visit variability in diastolic BP was associated with a faster decline of global cognitive function only among adults 55-64 years, independent of mean diastolic BP. Conclusion: Higher long-term BP visit-to-visit variability predicted a faster rate of cognitive decline among older adults.


2020 ◽  
Author(s):  
Ji Heon Lee ◽  
Ye Jin Jeon ◽  
Hyeon Chang Kim ◽  
Sun Jae Jung

Abstract Background: Information related to the association between cardiovascular health (CVH) level and cognitive dysfunction in the Korean population is very limited. The objective of our study was to investigate the effect of inflammatory status on the association between CVH and cognition.Methods: Data were obtained from the baseline assessments of the Cardiovascular and Metabolic Diseases Etiology Research Center study. Participants who completed fasting serum analysis, questionnaires, and cognitive function tests were included in the analyses, whereas those with a history of autoimmune disease were excluded. Cardiovascular Health in Ambulatory Care Research Team health index metrics, including smoking, physical activity, healthy diet, obesity, history of hypertension, and history of diabetes, were used to assess CVH. Cognitive function was evaluated with the Korean version of the Mini-Mental State Estimation for Dementia Screening. Inflammatory status was assessed based on a high-sensitivity C-reactive protein (hs-CRP) test.Results: Among 2,622 total participants (mean age 57.2 years; 1,792 women [68.3%]), 342 (13%), 1,520 (58%), and 760 (29%) had poor, intermediate, or ideal CVH, respectively. Logistic regression analysis demonstrated that CVH was not significantly associated with cognitive function. We further investigated the association between each component of CVH and low cognitive function by determining the hs-CRP level. Results showed that the only component affecting the association was hypertension history in men.Conclusions: Our findings suggest that CVH is not significantly associated with cognitive function in the middle-aged Korean population. In addition, inflammatory status had no significant effect on the association, and the only CVH-related factor affecting the association was hypertension history.Trial registration: KCT0001038, Clinical Research Information Service (CRIS)


Nutrients ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1683 ◽  
Author(s):  
Luke Stanaway ◽  
Kay Rutherfurd-Markwick ◽  
Rachel Page ◽  
Marie Wong ◽  
Wannita Jirangrat ◽  
...  

Nitrate-rich beetroot juice supplementation has been shown to improve cardiovascular and cognitive function in younger and older adults via increased nitric oxide production. However, it is unclear whether the level of effects differs between the two groups. We hypothesized that acute supplementation with nitrate-rich beetroot juice would improve cardiovascular and cognitive function in older and younger adults, with the potential for greater improvements in older adults. Thirteen younger (18–30 years) and 11 older (50–70 years) adults consumed either 150 mL of nitrate-rich beetroot juice (BR; 10.5 mmol nitrate) or placebo (PL; 1 mmol nitrate) in a double-blind, crossover design, 2.25 h prior to a 30-min treadmill walk. Plasma nitrate and nitrite concentrations, blood pressure (BP), heart rate (HR), cognitive function, mood and perceptual tests were performed throughout the trial. BR consumption significantly increased plasma nitrate (p < 0.001) and nitrite (p = 0.003) concentrations and reduced systolic BP (p < 0.001) in both age groups and reduced diastolic BP (p = 0.013) in older adults. Older adults showed a greater elevation in plasma nitrite (p = 0.038) and a greater reduction in diastolic BP (p = 0.005) following BR consumption than younger adults. Reaction time was improved in the Stroop test following BR supplementation for both groups (p = 0.045). Acute BR supplementation increased plasma nitrite concentrations and reduced diastolic BP to a greater degree in older adults; whilst systolic BP was reduced in both older and younger adults, suggesting nitrate-rich BR may improve cardiovascular health, particularly in older adults due to the greater benefits from reductions in diastolic BP.


2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 567-567
Author(s):  
Xia Li ◽  
Yuan Fang ◽  
Qi Qiu ◽  
Shixing Qian

Abstract This study aims to examine the association between arts related interests and cognition among older Chinese. Data were drawn from 3,243 participants (Mage=71.1, SD=7.8) in the China Longitudinal Aging Study collected in 2011. About 54.4% were female, the average education was eighth grade, 560 interested in music, 86 interested in drawing, and 69 interested in both. Those interested in music or drawing were more likely to enjoy tea and exercise like Taichi, and less likely to smoke or drink (p &lt; 0.01). Those interested in both reported best cognitive function, and those interested in music or drawing had better cognitive function than those without these interests (p&lt; 0.01). However, the difference in cognition between those interested in music and those without diminished after education was controlled. The effect of arts hobbies in cognition among older Chinese remains to be further examined within the context of education and associated lifestyle factors.


2018 ◽  
Vol 30 (12) ◽  
pp. 1827-1836 ◽  
Author(s):  
Jaime Perales ◽  
Ladson Hinton ◽  
Jeffrey Burns ◽  
Eric D. Vidoni

ABSTRACTObjectives:To assess the association between cardiovascular health and cognitive function among Mexican older adults.Design:Nationally representative cross-sectional survey.Setting:Households in Mexico.Participants:Individuals aged 50 years and older (n= 1,492) from the Mexico-SAGE project Wave 1.Measurements:A continuous and a categorical index of cardiovascular health was calculated based on exercise, smoking, body mass index, and blood pressure ranging from 0 to 4. Cognitive function was obtained by averaging the standardized scores (zscores) of five psychometric tests. Associations were conducted using linear regression.Results:The continuous index of cardiovascular health was not associated with cognitive function. Using the categorical index, participants with the best levels of cardiovascular (score of 4) health performed better on global cognitive function than groups with lower cardiovascular health (scores of 0, 0.41SD; 1, 0.39SD; and 2, 0.56SD). The association was moderated by age, reaching significance only among those 50–64 years old.Conclusions:If longitudinal research confirms these findings, results would suggest that dementia-related policies in Mexico need to focus on achieving optimal levels of cardiovascular health, especially in midlife.


2010 ◽  
Vol 6 ◽  
pp. S477-S477 ◽  
Author(s):  
Carmen A. Gonzalez-Rojas ◽  
Gloria Pino-Ramirez ◽  
Angelica G. Partida ◽  
Egle R. Silva ◽  
Gladys E. Maestre

Author(s):  
Tran Dai Tri Han ◽  
Keiko Nakamura ◽  
Kaoruko Seino ◽  
Vo Nu Hong Duc ◽  
Thang Van Vo

This study examined the prevalence of cognitive impairment among older adults in central Vietnam and the roles of communication (with or without communication devices) in the association between cognitive impairment and hearing loss. This cross-sectional study was performed on 725 randomly selected community-dwelling older adults aged ≥60 years from Thua Thien Hue province, Vietnam. Participants attended a face-to-face survey. Sociodemographic characteristics, social interaction with or without communication devices, health status and cognitive function using the Mini-Mental State Examination were reported. Ordinal logistic regression analysis was performed to quantify the association between hearing loss and cognitive function by frequency of communication with and without devices. Mild and severe cognitive impairment had prevalence rates of 23.6% and 19.3%, respectively. Cognitive impairment was more prevalent among older adults with hearing-loss, vision loss and difficulties with instrumental activities of daily living (IADL). The association between hearing loss and cognitive impairment was not significant when older adults had frequent communication with others using devices. This study presented the relatively high prevalence of cognitive impairment in community-dwelling older adults in Vietnam. Frequent communication using devices attenuated the association between hearing loss and cognitive impairment.


Author(s):  
Noah A. Schuster ◽  
Sascha de Breij ◽  
Laura A. Schaap ◽  
Natasja M. van Schoor ◽  
Mike J. L. Peters ◽  
...  

Abstract Purpose Delay of routine medical care during the COVID-19 pandemic may have serious consequences for the health and functioning of older adults. The aim of this study was to investigate whether older adults reported cancellation or avoidance of medical care during the first months of the COVID-19 pandemic, and to explore associations with health and socio-demographic characteristics. Methods Cross-sectional data of 880 older adults aged ≥ 62 years (mean age 73.4 years, 50.3% female) were used from the COVID-19 questionnaire of the Longitudinal Aging Study Amsterdam, a cohort study among community-dwelling older adults in the Netherlands. Cancellation and avoidance of care were assessed by self-report, and covered questions on cancellation of primary care (general practitioner), cancellation of hospital outpatient care, and postponed help-seeking. Respondent characteristics included age, sex, educational level, loneliness, depression, anxiety, frailty, multimorbidity and information on quarantine. Results 35% of the sample reported cancellations due to the COVID-19 situation, either initiated by the respondent (12%) or by healthcare professionals (29%). Postponed help-seeking was reported by 8% of the sample. Multimorbidity was associated with healthcare-initiated cancellations (primary care OR = 1.92, 95% CI = 1.09–3.50; hospital OR = 1.86, 95% CI = 1.28–2.74) and respondent-initiated hospital outpatient cancellations (OR = 2.02, 95% CI = 1.04–4.12). Depressive symptoms were associated with postponed help-seeking (OR = 1.15, 95% CI = 1.06–1.24). Conclusion About one third of the study sample reported cancellation or avoidance of medical care during the first months of the pandemic, and this was more common among those with multiple chronic conditions. How this impacts outcomes in the long term should be investigated in future research.


Author(s):  
Heloyse Elaine Gimenes Nunes ◽  
Evelinn Amarilha Faria ◽  
Paula Felippe Martinez ◽  
Silvio Assis de Oliveira-Júnior

Abstract This review analyzed the studies that evaluated cardiovascular health indicators (blood pressure, waist circumference, heart rate, glucose index and lipid blood) in recreational soccer players during adolescence, and identify possible associated factors. The search was performed in the electronic databases (PubMED, SciELO, LILACS, Scopus, SPORTDiscus and Web of Science). Inclusion criteria were: population composed of children and/or adolescents (10–19 years or average age up to 19 years); studies adolescents engaged in recreational soccer regularly and observational studies with cross-sectional or longitudinal design. The process of analysis of studies involved reading titles, abstracts and full texts. After these phases, seven articles were eligible. Regarding the design, all studies were cross-sectional. Of the total studies included, five presented moderate methodological quality values and two presented low methodological quality values, according to National Heart, Lung, and Blood Institute instrument. The most cardiovascular health indicators used in recreational soccer players during adolescence was waist circumference; three studies analyzed heart rate, two evaluated blood pressure, one analyzed insulin resistance and none of the included studies analyzed lipid profile. Factors associated were analyzed in four studies, being that sedentary time and body mass index (BMI) present association with at least one indicator of cardiovascular health.


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