scholarly journals Blood Glucose Changes during Neurosurgery

1979 ◽  
Vol 7 (1) ◽  
pp. 45-49
Author(s):  
Christopher G. Male
Keyword(s):  
Blood Glucose ◽  
Family History ◽  
Body Temperature ◽  
Older Patients ◽  
High Dose ◽  
Family History Of Diabetes ◽  
Induced Hypotension ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
History Of

Blood glucose levels were studied prospectively in 40 patients undergoing elective major craniotomy. A significant (p < 0.01) hyperglycaemic response was noted after scalp infiltration with adrenaline and incision (0.5 mmol/l) and with continued surgery (0.9 mmol/l). Patients aged 50 years and under showed a significantly greater rise with adrenaline and incision than older patients (0.8 compared with 0.4 mmol/l p < 0.01). Preoperative high dose steroid therapy did not modify the response Blood glucose changes were unrelated to sex, obesity, a family history of diabetes, the duration of starvation, intraoperative body temperature, anaesthetic technique induced hypotension or blood loss.

Study of Diabetic Mellitus and Knowledge of Lotion Foot Care on the Community

2018 ◽  
Vol 9 (3) ◽  
Author(s):  
Hariyadi DM ◽  
Athiyah U ◽  
Hendradi E ◽  
Rosita N ◽  
Erawati T ◽  
...  
Keyword(s):  
Blood Glucose ◽  
T Test ◽  
Small Scale ◽  
Scale Production ◽  
Foot Care ◽  
Diabetic Mellitus ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Before And After ◽  
History Of

The prevention of Diabetic Mellitus (DM) and its complications is the main aim of this study, in addition to the training of lotion foot care application and the development of small scale industry. The research team delivered knowledge in the form of training on Diabetic Mellitus, healthy food, treatment and prevention of complications, and small-scale production of cosmetic products. The aim of this study was to determine the correlation between training on diabetic and lotion foot care application as preventive measures against diabetic complications on the patient's blood glucose levels in the community of residents in Banyuurip Jaya, Surabaya. It was expected from this training that the knowledge of the residents increases and people living with diabetic undergo lifestyle changes and therefore blood sugar levels can be controlled. The parameters measured in this research were blood glucose levels, the anti diabetic drug types consumed, and compliance on diabetics. This study used the data taken from 60 patients with DM over a period of one month. Questionnaires and log books was used to retrieve data and changes in blood glucose levels in diabetic patients. The results showed the demographic data of patients with type 2 diabetic of 85% female and 15% male, with the range of patients aged of 61-70 years of 46.67% and had history of diabetic (90%). The history of drugs consumed by respondents was anti diabetic drugs such as metformin (40%), glimepiride (33.37%) and insulin (6.67%). In addition, the increased knowledge of DM patients after being given the training compared to before training was shown in several questions in the questionnaire. A statistical analysis using t-test analyzed a correlation between training provided in order to enhance understanding of the patient, as well as correlation with blood glucose levels. A paired T-test showed that there was a relationship between the knowledge of trainees before and after training (p less than 0.05). An interesting result was that there was no relationship between blood glucose levels before and after training provided (p> 0.05).

Knowledge, Attitude, practice, and their associated factor towards Diabetes Mellitus among peoples live in Debre Markos Town, North West Ethiopia, Amhara Regional State, Ethiopia 2020 GC

2022 ◽  
Author(s):  
Addisu Simachew ◽  
Habtamu Temesgen
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Family History ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Educational Level ◽  
Good Practice ◽  
Favorable Attitude ◽  
Family History Of Diabetes ◽  
History Of

Abstract Background: Diabetes mellitus is a group of metabolic disease in which there is high blood glucose level over a prolonged period of time, chronic multi system disease related to abnormal insulin production, impaired insulin utilization and both. Risk of diabetes are obesity, being young or old age, family history of diabetes, history gestational diabetes, impaired, glucose metabolism, physical inactivity and ethnicity/race respectively. In type one diabetes mellitus insulin injection is needed to control the blood glucose level where as in type two diabetes mellitus the first line treatment is life style modification like diet management, exercise, and weight reduction then if uncontrolled use oral hypoglycemic agent.Objective: The main aim of the study was to assess Knowledge, Attitude, practice and their associated factor towards diabetes mellitus in Debre Markos town, northwest , Amhara Regional state, Ethiopia 2020 GC.Methodology: a community based cross-sectional study was conduct from June to July for 403 respondents using systematic random sampling technique to select the household after select the first household by lottery method. Data collected through self administered questions, the collected data process and analysis manually using pen, pencil, tally sheet and present in tables, graphs and charts respectively.Result: based on our study 138 (34.6%) of the respondents were classified as having inadequate knowledge, whereas 261(65.4%) of the respondents were deemed to be knowledgeable. from the participant 186(46.6%) had unfavorable attitude while 213(53.4%) had favorable attitude towards diabetes mellitus. Overall practice of the participant was 37.8% good practice and 62.2% poor practice. Single individuals 5.133 times (AOR=5.133, CI=1.737, 15.051) more likely knowledgeable than those divorced. Family history of diabetes mellitus 5.019 times (AOR=5.02- CI=1.59-15.76) more likely had favorable attitude than those who had no family history of DM. secondary educational level were 2.34 times (AOR=2.34, CI=1.14- 0.78) more likely good practice than those with able to read and write and persons in primary educational level. DM patients 2.811 times (AOR=2.81-95%, CI=0.99- 7.97) more likely good practice than non-diabetic.Conclusion: majority of the participant’s relatively knowledgeable. The overall attitude of the participant was more than half was favorable attitude. Majority of the study participants were poor practice regarding to DM controlling and management. Knowledge of the participant highly significant association with marital status, income and practice, practice also strong association with level of education and attitude significantly associated with family history of DM

scholarly journals Investigation of the Polymorphic Region in the 5' Flanking Region of the Insulin Gene in Patients with Alzheimer's Disease

1986 ◽  
Vol 13 (S4) ◽  
pp. 471-474
Author(s):  
Michael Fisman ◽  
Valerie M. Watt
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Family History ◽  
Venous Blood ◽  
Insulin Gene ◽  
Restriction Enzyme Digestion ◽  
Polymorphic Region ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
History Of

Abstract:A potential relationship between Alzheimer's Disease (AD) and insulin gene expression was suggested by the observation that patients with AD have altered levels of fasting blood sugar and insulin. Since polymorphisms in the region 5' to the insulin gene have been associated with blood glucose levels, we have studied this polymorphism in AD patients. Subjects were 19 nondiabetic AD patients with symptoms of aphasia and apraxia and a family history of AD; and 20 age and sex-matched nondiabetic controls without family history of AD. The 5' polymorphic region of the insulin gene was analyzed by restriction enzyme digestion of DNA extracted from whole venous blood. We did not observe a correlation between the size of the 5' polymorphic region and AD.

scholarly journals Glycemic Variability in Diabetes Increases the Severity of Influenza

mBio ◽  
2020 ◽  
Vol 11 (2) ◽  
Author(s):  
Rebecca J. Marshall ◽  
Pornthida Armart ◽  
Katina D. Hulme ◽  
Keng Yih Chew ◽  
Alexandra C. Brown ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Glycemic Variability ◽  
Endothelial Barrier ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Severe Influenza ◽  
Increased Risk ◽  
History Of

ABSTRACT People with diabetes are two times more likely to die from influenza than people with no underlying medical condition. The mechanisms underlying this susceptibility are poorly understood. In healthy individuals, small and short-lived postprandial peaks in blood glucose levels occur. In diabetes mellitus, these fluctuations become greater and more frequent. This glycemic variability is associated with oxidative stress and hyperinflammation. However, the contribution of glycemic variability to the pathogenesis of influenza A virus (IAV) has not been explored. Here, we used an in vitro model of the pulmonary epithelial-endothelial barrier and novel murine models to investigate the role of glycemic variability in influenza severity. In vitro, a history of glycemic variability significantly increased influenza-driven cell death and destruction of the epithelial-endothelial barrier. In vivo, influenza virus-infected mice with a history of glycemic variability lost significantly more body weight than mice with constant blood glucose levels. This increased disease severity was associated with markers of oxidative stress and hyperinflammation both in vitro and in vivo. Together, these results provide the first indication that glycemic variability may help drive the increased risk of severe influenza in people with diabetes mellitus. IMPORTANCE Every winter, people with diabetes are at increased risk of severe influenza. At present, the mechanisms that cause this increased susceptibility are unclear. Here, we show that the fluctuations in blood glucose levels common in people with diabetes are associated with severe influenza. These data suggest that glycemic stability could become a greater clinical priority for patients with diabetes during outbreaks of influenza.

Effects of ethanol and tertiary butanol on blood glucose levels and body temperature of rats

Alcohol ◽  
1989 ◽  
Vol 6 (3) ◽  
pp. 183-187 ◽  
Author(s):  
Dale M. Atrens ◽  
Andrew Van Der Reest ◽  
Bernard W. Balleine ◽  
JoséA. Menéndez ◽  
Stephen M. Siviy
Keyword(s):  
Blood Glucose ◽  
Body Temperature ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Tertiary Butanol

Streptozotocin-induced diabetes differentially affects sympathetic innervation and control of plantar metatarsal and mesenteric arteries in the rat

2013 ◽  
Vol 304 (2) ◽  
pp. H215-H228 ◽  
Author(s):  
Niloufer J. Johansen ◽  
Diana Tripovic ◽  
James A. Brock
Keyword(s):  
Blood Glucose ◽  
Vascular Function ◽  
Neural Control ◽  
Sympathetic Innervation ◽  
Nerve Fibers ◽  
Transmural Pressure ◽  
Mesenteric Arteries ◽  
High Dose ◽  
Glucose Levels ◽  
Blood Glucose Levels

In humans neural control of arterial vessels supplying skin in the extremities is particularly vulnerable to the effects of diabetes. Here the streptozotocin (STZ) rat model of type 1 diabetes was used to compare effects on neurovascular function in plantar metatarsal arteries (PMAs), which supply blood to skin of hind paw digits, with those in mesenteric arteries (MAs). Twelve weeks after STZ (60 mg/kg ip), wire myography was used to assess vascular function. In PMAs, lumen dimensions were unchanged but both nerve-evoked contractions and sensitivity to α1 (phenylephrine, methoxamine)- and α2 (clonidine)-adrenoceptor agonists were reduced. The density of perivascular nerve fibers was also reduced by ∼25%. These changes were not observed in PMAs from STZ-treated rats receiving either a low dose of insulin that did not greatly reduce blood glucose levels or a high dose of insulin that markedly reduced blood glucose levels. In MAs from STZ-treated rats, nerve-evoked increases in force did not differ from control but, because lumen dimensions were ∼20% larger, nerve-evoked increases in effective transmural pressure were smaller. Increases in effective transmural pressure produced by phenylephrine or α,β-methylene ATP in MAs from STZ-treated rats were not smaller than control, but the density of perivascular nerve fibers was reduced by ∼10%. In MAs, the increase in vascular dimensions is primarily responsible for reducing effectiveness of nerve-evoked constrictions. By contrast, in PMAs decreases in both the density of perivascular nerve fibers and the reactivity of the vascular muscle appear to explain impairment of neurovascular transmission.

Partial protection against streptozotocin-induced hyperglycaemia by superoxide dismutase linked to polyethylene glycol

1984 ◽  
Vol 107 (3) ◽  
pp. 390-394 ◽  
Author(s):  
kjell Asplund ◽  
Kjell Grankvist ◽  
Stefan Marklund ◽  
Inge-Bert Täljedal
Keyword(s):  
Superoxide Dismutase ◽  
Polyethylene Glycol ◽  
Blood Glucose ◽  
Superoxide Radicals ◽  
High Dose ◽  
Partial Protection ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Pre Treatment

Abstract. To test the possible role of superoxide radicals in the diabetogenic action of streptozotocin, blood glucose levels were measured in mice after a single high-dose (150 mg/kg body weight) or multiple low-dose (40 mg/kg for 5 days) injections of streptozotocin. Pre-treatment 6 h before streptozotocin with 250–300 mg/kg superoxide dismutase coupled to polyethylene glycol reduced the hyperglycaemic response in mice injected with a single dose of streptozotocin. The blood glucose levels after multiple low doses of streptozotocin were not affected by superoxide dismutase-polvethvlene glycol. Enzymatically inactive superoxide dismutase did not affect the development of hyperglycaemia. The results suggest that superoxide radicals may play a role in the diabetogenic action of streptozotocin injected as a high-dose single bolus.

scholarly journals Deteksi Dini Peningkatan Glukosa Dalam Darah di RW 07 Kelurahan Pekayon, Pasar Rebo

2020 ◽  
Vol 2 (1) ◽  
pp. 39
Author(s):  
Dwi Agustina
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Family History ◽  
Early Detection ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Metabolic Diseases ◽  
Family History Of Diabetes ◽  
The People ◽  
History Of

Diabetes Mellitus is one of the chronic illness. DM is metabolic diseases with characteristic hyperglycemia that occur di to abnormal insulin secretion, insulin performance or both (ADA, 2010). Depend on PERKENI (2011), complication of DM occur from uncontrolled blood glucose level, such as neuropathy, hypertension, coronary heart disease, retinopathy, nephropathy and gangrene. The people who have high risk of DM are high-carbohydrate diets, have a family history of diabetes Mellitus. there for we need to early detection to be prevention became Diabetes Mellitus disease. Early detection of activities of patients with DM are held at RW 07 due to DM risk faktor that occur in that area. Community Service Activities were carried out on Wednesday, March 23, 2016 at the RW 07 Pekayon village meeting hall. Activities include measuring glucose level and counseling. For the results of early detection blood glucose level, it was found that 56 out of 82 residents experienced and increase in blood glucose level (68%). Most of them carry out consultations related to diet and Diabetes Mellitus family history

scholarly journals Prevalence of pre-diabetes in adolescents aged 11-17 years with high risk factors

2021 ◽  
Author(s):  
Kuppan Balamurugan ◽  
Rajangam Ponprabha ◽  
Veeramani Sivashankari
Keyword(s):  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Family History ◽  
High Risk ◽  
Acanthosis Nigricans ◽  
Early Stage ◽  
Family History Of Diabetes ◽  
History Of ◽  
Mean Blood Glucose

Background: Obesity is a rising global epidemic in children which leads to pre-diabetes and overt diabetes. Identification at early stage helps in early intervention. This study was undertaken to study the prevalence of pre-diabetes in urban school going adolescents aged 11-17 years with high risk factors.Methods: This was a prospective cross-sectional study conducted in Chennai, India between December 2011 and November 2012. Overweight or obese adolescents in the age group 11-17 years, either with family history of diabetes or acanthosis nigricans or both were included. After obtaining informed consent from parents, history was obtained in pre-tested questionnaire.Results: 148 adolescents were enrolled in the study (n=148), 71.62% were females, mean weight was 59.54±10.44 kg, mean height was 150.92±8.62 cm, mean BMI was 26.19±3.23 and mean blood glucose was 82.1 mg/dl. 60.81% of subjects were overweight and others obese. Girls had statistically significant higher mean weight and mean BMI than boys. 78.37% had acanthosis nigricans, 47.29% had family history of diabetes, 12.16% had pre-diabetes and the mean blood glucose in pre-diabetics was 104.9 mg/dl. Pre-diabetes was higher in adolescents with family history of diabetes (p=0.038).Conclusions: Recognition of risk of type 2 diabetes in the asymptomatic pre-diabetes phase needs to be emphasized and targeted screening of high risk children for pre-diabetes seems to be justified. The morbidity and mortality of youth onset type 2 diabetes can be reduced only by early detection and treatment.

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