Dorsal Preservation Rhinoplasty: A Literature Review

2021 ◽  
pp. 074880682110658
Author(s):  
Mark R. Stevens ◽  
Shohreh Ghasemi ◽  
Fargol Mashhadi Akbar Boojar ◽  
Mahmood Dashti
Keyword(s):  
Search Strategy ◽  
Randomized Clinical Trials ◽  
Case Reports ◽  
Data Extraction ◽  
Experimental Studies ◽  
Underlying Structure ◽  
Medical Databases ◽  
Manual Search ◽  
Total Preservation

Acceptance of the preservation principle in rhinoplasty surgery has increased dramatically, and surgeons worldwide are now performing preservation rhinoplasty, leading to an expanding list of indications and techniques. Rhinoplasty surgeons are increasingly opting for rhinoplasty preservation because of its conservative approach and more predictable outcome. This review aims to evaluate the efficacy of dorsal preservation rhinoplasty, as well as the techniques, indications, surgical protocols, complications, and any practical challenges associated with this type of rhinoplasty. A number of medical databases, including Medline-PubMed, Embase, and Scopus, were searched. These searches were supplemented with a manual search using the keyword “preservation rhinoplasty” (PR) during the 1970 to May 2020 time span. The search strategy was limited to case reports, randomized clinical trials, and prospective studies of preservation dorsal rhinoplasty in journals published in English. A total of 150 articles that incorporated preservation dorsal rhinoplasty as a newer surgical technique were reviewed: 136 from PubMed, 17 experimental studies from Embase, 17 clinical studies from Scopus, and 8 studies identified by data extraction. Preservation rhinoplasty represents a paradigm shift in rhinoplasty philosophy. While techniques continue to improve, the philosophy remains the same: preserving and reshaping the existing nasal structures. Although not all patients benefit from and are satisfied with PR and some may only benefit from partial PR, preserving the anatomy allows for a more intuitive operation and natural results. For a more exhaustive review, readers are encouraged to turn their attention to dorsal preservation as a versatile and adaptable technique. Dorsal preservation avoids long-term issues with the middle vault and keystone area, and the patient benefits from total preservation, as the underlying structure can be reshaped without disruption.

scholarly journals Rituximab monotherapy for splenic marginal zone lymphoma with villous lymphocytes: report on long-term disease control for two patients with recurrence after splenectomy

2010 ◽  
Vol 128 (6) ◽  
pp. 375-377 ◽  
Author(s):  
Márcio Debiasi ◽  
Marluce Hehnemann ◽  
Bernardo Garicochea
Keyword(s):  
Randomized Clinical Trials ◽  
Marginal Zone ◽  
Treatment Guidelines ◽  
Case Reports ◽  
Specific Treatment ◽  
Marginal Zone Lymphoma ◽  
Splenic Marginal Zone Lymphoma ◽  
Purine Analogues ◽  
Relapsed Lymphoma

CONTEXT: Splenic marginal zone lymphoma (SMZL) is a lymphoproliferative B-cell disorder that has a favorable prognosis, with estimated overall five-year survival of 70%. The majority of symptomatic patients undergo splenectomy, while a few receive first-line chemotherapy, especially with purine analogues. There are no specific treatment guidelines for patients for whom splenectomy fails to provide a cure. It is still unclear whether these patients should undergo cytotoxic chemotherapy, considering they have now a relapsed lymphoma (which is theoretically more aggressive), or whether they should be spared from treatments of greater toxicity, given that their disease usually develops with a more indolent course, even when it recurs. CASE REPORT: Here, we present two patients whose disease recurred after splenectomy and for whom rituximab monotherapy provided satisfactory treatment. From these cases, it can be suggested that postponement of cytotoxic treatments may be possible in at least some situations. It needs to be emphasized that the evidence to support this approach is based only on case reports, since there are no randomized clinical trials on this subject.

scholarly journals Emergency Management of Paraphimosis

2003 ◽  
Vol 10 (4) ◽  
pp. 253-257 ◽  
Author(s):  
Ch Chung
Keyword(s):  
Case Reports ◽  
Data Extraction ◽  
Treatment Options ◽  
Case Series ◽  
Treatment Modalities ◽  
Invasive Treatment ◽  
Manual Search ◽  
Study Selection ◽  
Library Network ◽  
Randomised Controlled

Objective To review the treatment modalities available for paraphimosis, with special emphasis on those applicable to the emergency department. Data source Relevant medical literature was searched through MEDLINE, EMBASE, CINAHL, and Cochrane Database. Manual search was performed in books on Urology, General Surgery and Emergency Medicine available in the Hospital Library. Further information was obtained through the Internet at < www.infoseek.com >. References cited in articles were also retrieved. Study selection Key words for the literature, Internet and textbook search were ‘paraphimosis’ and ‘treatment’. All available years of study were reviewed. Data extraction Relevant full text articles were obtained through the hospital library network. Original articles, review papers, medical practice, case reports, and relevant book chapters were reviewed. Data synthesis There were no prospective, randomised, controlled studies available. The majority were case series and expert experience or opinions only. Currently, a multitude of non-invasive and invasive treatment options are available, including manual reduction, help of non-crushing tissue forceps, puncture technique and dorsal slit. Conclusion All treatment methods are within the capability of the emergency physician. Hospitalization should rarely be required, unless there are serious complications.

Meperidine-Related Seizures Associated with Patient-Controlled Analgesia Pumps

1993 ◽  
Vol 27 (1) ◽  
pp. 29-32 ◽  
Author(s):  
Kathleen O. Hagmeyer ◽  
Laurie S. Mauro ◽  
Vincent F. Mauro
Keyword(s):  
Case Reports ◽  
Review Literature ◽  
Term Therapy ◽  
Patient Controlled Analgesia ◽  
Data Synthesis ◽  
Manual Search ◽  
High Doses ◽  
Long Term Therapy ◽  
Search Index

OBJECTIVE: To report three cases of meperidine-related seizures when meperidine was administered via patient-controlled analgesia pump (PCAP) and to review literature related to meperidine-associated seizures. DATA SOURCES: Case reports and review articles identified by a computerized search (MEDLINE) and manual search ( Index Medicus). DATA SYNTHESIS: PCAPs are being used frequently to relieve the pain of sickle cell crisis as well as pain from many other etiologies. We report three cases of meperidine-related seizures associated with its administration via PCAP. Each of the patients received either relatively high doses, long-term therapy, or both. Meperidine has been associated with seizure activity when administered via traditional routes. Previously identified risk factors for the development of meperidine-related seizures include renal failure, high meperidine dosages, and coadministration of hepatic enzyme-inducing medications or phenothiazines. CONCLUSIONS: Meperidine administered via PCAP may be associated with seizures. Optimally, an alternative analgesic should be administered when this route is used.

scholarly journals Colchicine for children with pericarditis: systematic review of clinical studies

2016 ◽  
Vol 101 (10) ◽  
pp. 953-956 ◽  
Author(s):  
Samer Alabed ◽  
Giordano Pérez-Gaxiola ◽  
Amanda Burls
Keyword(s):  
Systematic Review ◽  
Case Reports ◽  
Data Extraction ◽  
Experimental Studies ◽  
Case Series ◽  
Eligibility Criteria ◽  
Double Blind ◽  
Randomised Controlled

ObjectiveTo review the evidence for the efficacy and safety of colchicine in children with pericarditis.DesignSystematic review.Search strategyThe following databases were searched for studies about colchicine in children with pericarditis (June 2015): Cochrane Central, Medline, EMBASE and LILACS.Eligibility criteriaAll observational and experimental studies on humans with any length of follow-up and no limitations on language or publication status were included. The outcomes studied were recurrences of pericarditis and adverse events.Data extractionTwo authors extracted data and assessed quality of included studies using the Cochrane risk of bias tool for non-randomised trials.ResultsTwo case series and nine case reports reported the use of colchicine in a total of 86 children with pericarditis. Five articles including 74 paediatric patients were in favour of colchicine in preventing further pericarditis recurrences. Six studies including 12 patients showed that colchicine did not prevent recurrences of pericarditis.LimitationsNo randomised controlled trials (RCTs) were found.ConclusionsAlthough colchicine is an established treatment for pericarditis in adults, it is not routinely used in children. There is not enough evidence to support or discourage the use of colchicine in children with pericarditis. Further research in the form of large double-blind RCTs is needed to establish the efficacy of colchicine in children with pericarditis.

scholarly journals Outcome of interventions in elderly persons classified according to the Fried frailty phenotype: an integrative review

2019 ◽  
Vol 22 (3) ◽  
Author(s):  
Letice Dalla Lana ◽  
Maria da Graça Oliveira Crossetti
Keyword(s):  
Randomized Clinical Trials ◽  
Web Of Science ◽  
Elderly Persons ◽  
Frailty Phenotype ◽  
Term Care ◽  
Manual Search ◽  
Final Sample ◽  
Care Facilities ◽  
Combined Interventions

Abstract Objective: To analyze the interventions carried out with elderly persons classified according to the Fried frailty phenotype criteria and the outcomes obtained. Method: The PubMed, Embase, Scopus, CINAHL, PEDro, SciELO, BVS and Web of Science portals were used, and a manual search was applied to identify the interventions implemented in elderly persons aged over 60 years, which were able to modify the scores of the frailty phenotype criteria and other outcomes. Results: The final sample totaled 14 randomized clinical trials published between 2001 and 2018. The combined interventions of exercise, orientation and nutritional supplementation with or without cognitive training presented better outcomes for the frailty criteria and other clinical outcomes in pre-frail and frail elderly persons living in the community and in long-term care facilities. Conclusion: The implementation of combined interventions sustains frailty as a reversible and multifactorial syndrome.

Natalizumab for the Treatment of Multiple Sclerosis and Crohn's Disease

2005 ◽  
Vol 39 (11) ◽  
pp. 1833-1843 ◽  
Author(s):  
Kendra A Keeley ◽  
Michael P Rivey ◽  
Douglas R Allington
Keyword(s):  
Multiple Sclerosis ◽  
Inflammatory Bowel Disease ◽  
Clinical Trials ◽  
Bowel Disease ◽  
Randomized Clinical Trials ◽  
Case Reports ◽  
Data Extraction ◽  
Data Sources ◽  
Medline Search ◽  
Inflammatory Bowel

OBJECTIVE To review the pharmacology, pharmacokinetics, safety, and pivotal clinical trials for natalizumab in the treatment of multiple sclerosis (MS) and inflammatory bowel disease. DATA SOURCES A PubMed/MEDLINE search was conducted (1966–June 2005), and information was obtained from Iowa Drug Information Services. Additional data sources included meeting abstracts, bibliographies from identified articles, and information from the manufacturer. STUDY SELECTION AND DATA EXTRACTION Studies and review articles examining natalizumab were evaluated. All published, randomized clinical trials evaluating natalizumab in MS and IBD were included in this review. DATA SYNTHESIS Natalizumab is the first drug in a new class of agents called selective adhesion molecule inhibitors. It has shown promising results in MS and inflammatory bowel disease and appears superior compared with current therapies in reducing relapse rates. However, 3 recent, confirmed case reports of progressive multifocal leukoencephalopathy (PML) create concern about natalizumab's use in combination with existing therapies or in undefined patient subgroups. Natalizumab was voluntarily withdrawn from the market in March 2005 while the drug's safety is further evaluated. CONCLUSIONS Although long-term efficacy and safety of natalizumab have not been established, available data indicate that it is a novel drug for patients with MS or inflammatory bowel disease. Analysis of its possible association with PML will determine the risk–benefit evaluation and eventual place in therapy for natalizumab.

scholarly journals A REVIEW ON BIOGENIC PROPERTIES OF STEM BARK OF TERMINALIA ARJUNA: AN UPDATE

2018 ◽  
Vol 11 (8) ◽  
pp. 35 ◽  
Author(s):  
Dinanath Gaikwad ◽  
Namdeo Jadhav
Keyword(s):  
Antioxidant Activity ◽  
Web Of Science ◽  
Case Reports ◽  
Experimental Studies ◽  
Stem Bark ◽  
Lipid Lowering ◽  
Terminalia Arjuna ◽  
Alternative Systems ◽  
Arjunolic Acid

The traditional and alternative systems of medicine have been resulting more than 85% of the drugs from a plant source. Terminalia arjuna (T. arjuna) stem bark contain glycosides, ample quantities of flavonoids, tannins, and minerals. Flavonoids have been identified to exert antioxidant, anti-inflammatory, and lipid-lowering effects while glycosides are cardiotonic, thus making T. arjuna bark inimitable. In this review, an attempt has been made to discuss various aspects of its ethnomedical, phytochemical, pharmacological, and clinical relevance to various ailments condition. Available data from PubMed, Science Direct, and Web of Science were reviewed. Review articles, case reports, and clinical studies were included. Ultimately, after the elimination of repetitive information, 60 articles were identified. Most of the studies, both experimental and clinical, have suggested that T. arjuna bark possesses anti‑ischemic, antioxidant, and hypolipidemic activity. Its useful phytoconstituents are triterpenoids, flavonoids, glycosides, tannins, phenolics, and arjunolic acid. Experimental studies have revealed that T. arjuna bark exerting significant cardioprotective and as potent antioxidant activity. So far, no serious side effects have been reported with T. arjuna bark therapy. However, its long‑term safety still remains to be elucidated. T. arjuna bark has been found quite useful as cardioprotective agent. The present comprehensive update review is, therefore, an effort to give detailed information on T. arjuna stem bark for overall management of several ailments.

Searching MEDLINE for Randomized Clinical Trials Involving Care of the Newborn

PEDIATRICS ◽  
1989 ◽  
Vol 83 (4) ◽  
pp. 543-546
Author(s):  
Haresh Kirpalani ◽  
Barbara Schmidt ◽  
K. Ann McKibbon ◽  
R. Brian Haynes ◽  
John C. Sinclair
Keyword(s):  
Clinical Trials ◽  
Search Strategy ◽  
Randomized Clinical Trials ◽  
Human Subjects ◽  
Newborn Care ◽  
Predictive Values ◽  
Hand Search ◽  
Medline Search ◽  
Manual Search ◽  
Sensitivity Specificity

Randomized clinical trials make up only a small fraction of published articles concerning care of the newborn infant and an even smaller fraction of articles about all human subjects. The busy pediatrician who wants to keep abreast of the medical literature requires strategies to detect such relevant studies promptly and reliably. Computer searching of MEDLINE is an attractive, potentially powerful but not sufficiently validated means of achieving this goal. Therefore, the sensitivity, specificity, and positive predictive value of two MEDLINE search strategies designed to detect randomized clinical trials for prevention and treatment of newborn diseases among all original articles about human subjects appearing in ten pediatric and general medical journals during 1985 were determined. The yield of both MEDLINE searches was compared to that of a manual search. Fifty-three randomized clinical trials of newborn care were identified by hand search among 233 articles concerning care of the newborn and 2,988 original articles about human subjects. The sensitivities of the MEDLINE searches were 53% and 34%, respectively, and the positive predictive values were 82% and 69%, respectively. Specificity of both computer searches was virtually 100%. Twenty-one randomized clinical trials were not identified by either MEDLINE search strategy, 17 of them for failure of the indexer to assign any methodologic terms at all or failure to assign sufficiently stringent methodologic terms. Consequently, sensitivities were higher, 77% and 68% respectively, when no methodologic terms were used during repeat searches. However, positive predictive values decreased concomitantly to 20% or less. It is concluded that searching MEDLINE for randomized clinical trials is not yet sufficiently sensitive to be recommended as the sole strategy of keeping up with this literature.

scholarly journals Statins and diabetes: focus on pitavastatin

2020 ◽  
Vol 11 (2) ◽  
pp. 40-49
Author(s):  
Soreiia A. Urazgildeeva
Keyword(s):  
Risk Factors ◽  
Clinical Trials ◽  
Glucose Metabolism ◽  
Statin Therapy ◽  
Randomized Clinical Trials ◽  
Preventive Measures ◽  
Experimental Studies ◽  
Minimal Risk ◽  
Meta Analyses

In this review, the focus is to investigate the effects of long-term statin therapy on glucose metabolism. The author analyzed the evidences of randomized clinical trials, meta-analyses, and experimental studies indicating the diabetogenic effect of the most of statins. Possible mechanisms of influence of statins on carbohydrate metabolism are presented. Particular attention is paid to the place of pitavastatin, due to its low diabetogenicity and minimal risk of drug interactions, as well as the need of taking into consideration the risk factors of diabetes and the preventive measures in patients receiving statin therapy.

scholarly journals Liver Damage Associated withPolygonum multiflorumThunb.: A Systematic Review of Case Reports and Case Series

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Xiang Lei ◽  
Jing Chen ◽  
Jingtian Ren ◽  
Yan Li ◽  
Jingbo Zhai ◽  
...  
Keyword(s):  
Systematic Review ◽  
Liver Damage ◽  
Liver Toxicity ◽  
Case Reports ◽  
Case Series ◽  
Polygonum Multiflorum ◽  
Medical Databases ◽  
Chinese Patent ◽  
Relevant Factors

Objective. To summarize the characteristics and analysis of relevant factors and to give references for prevention and further study of liver damage associated withPolygonum multiflorumThunb. (HSW), we provide a systematic review of case reports and case series about liver damage associated with HSW.Methods. An extensive search of 6 medical databases was performed up to June 2014. Case reports and case series involving liver damage associated with HSW were included.Results. This review covers a total of 450 cases in 76 articles. HSW types included raw and processed HSW decoction pieces and many Chinese patent medicines that contain HSW. Symptoms of liver damage occur mostly a month or so after taking the medicine, mainly including jaundice, fatigue, anorexia, and yellow or tawny urine. Of the 450 patients, two cases who received liver transplantation and seven who died, the remaining 441 cases recovered or had liver function improvement after discontinuing HSW products and conservative care.Conclusion. HSW causes liver toxicity and may cause liver damage in different degrees and even lead to death; most of them are much related to long-term and overdose of drugs. Liver damage associated with HSW is reversible, and, after active treatment, the majority can be cured. People should be alert to liver damage when taking HSW preparations.

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