scholarly journals A New Classification of Function and Disability in China

2012 ◽  
Vol 24 (5) ◽  
pp. 779-798 ◽  
Author(s):  
Jama L. Purser ◽  
Qiushi Feng ◽  
Zeng Yi ◽  
Helen Hoenig
Keyword(s):  
Older Adults ◽  
Physical Performance ◽  
Environmental Predictors ◽  
New Classification ◽  
Chinese Older Adults ◽  
Rural Living ◽  
Healthy Longevity ◽  
Prevalent Subtype ◽  
Performance Limitations ◽  
And Performance

Objectives: To develop a new classification method to describe incidence and prevalence of function and disability and their predictors in Chinese older adults. Methods: Data were obtained from 16,020 older adults in the 2002 wave of Chinese Longitudinal Healthy Longevity Survey (CLHLS). The subtypes of function and disability were defined by combining physical performance (PP) tests and self-reported assessments of activities of daily living (ADL). Results: The most prevalent subtype involved PP limitations without ADL dependency. Rural living made it more likely that an individual with physical performance limitations would be independent in ADL, whereas city residence made dependence in ADL more likely, regardless of whether performance limitations were present. Discussion: Self-reported and performance-based tools can be used in combination to estimate conceptually different subtypes of function and disability, with different epidemiological rates of incidence and different social, medical, and environmental predictors.

scholarly journals Orofacial Pain Symptoms Among Chinese Older Adults in the Last Year of Life

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 32-32
Author(s):  
Yaolin Pei ◽  
Xiang Qi ◽  
Xi Chen ◽  
Bei Wu
Keyword(s):  
Older Adults ◽  
Joint Pain ◽  
Orofacial Pain ◽  
Lower Socioeconomic Status ◽  
Chinese Older Adults ◽  
Healthy Longevity ◽  
Lower Socioeconomic ◽  
Natural Teeth ◽  
Jaw Joint ◽  
Pain Symptoms

Abstract The aims of this study were to examine the prevalence of orofacial pain symptoms and its associated factors in Chinese older adults in the last year of life. We retrospectively followed 1,646 participants (60 years or older) in the last year of life to death from the Chinese Longitudinal Healthy Longevity Survey (CLHLS). The 6-month prevalence of toothache and jaw joint pain or facial pain for older adults in the last year of life to death were 14.1% and 4.5%, respectively. Older adults who had lower socioeconomic status, were smokers, and had any chronic disease tended to have orofacial pain symptoms. This study generated interesting but counterintutive findings that Chinese older adults who brusehed their teeth at least daily and those who had at least one natural teeth were more likely to have orofacial pain. It is important to include dental care as a part of end-of-life medical treatment.

scholarly journals Apolipoprotein E Genotype, Meat, Fish, and Egg Intake in Relation to Mortality Among Older Adults: A Longitudinal Analysis in China

2021 ◽  
Vol 8 ◽  
Author(s):  
Xurui Jin ◽  
Shangzhi Xiong ◽  
Changzheng Yuan ◽  
Enying Gong ◽  
Xian Zhang ◽  
...  
Keyword(s):  
Older Adults ◽  
Apolipoprotein E ◽  
Cox Regression ◽  
Population Based ◽  
Fish Intake ◽  
Chinese Older Adults ◽  
Healthy Longevity ◽  
All Cause Mortality ◽  
Diet Pattern ◽  
Interactive Relationship

Introduction: The interactions between apolipoprotein E (APOE) genotype and diet pattern changes were found significant in several trials, implying that APOE gene may modify the effect of animal protein-rich food on health outcomes. We aim to study the interaction of APOE genotype with the effect of meat, fish and egg intake on mortality.Methods: This population-based study enrolled 8,506 older adults (mean age: 81.7 years, 52.3% female) from the Chinese Longitudinal Healthy Longevity Study. The intake frequency of meat, fish and egg was assessed by 3-point questions at baseline. Cox regression was conducted to calculate the hazard ratios for all-cause mortality of intake levels of meat, fish and egg. The analyses were stratified by APOE genotype and sex. The analyses were performed in 2020.Results: In the multivariable-adjusted models, meat and fish intake was associated with all-cause mortality (high vs. low intake: meat: HR: 1.14, 95% CI: 1.01, 1.28; fish: HR: 0.83, 95% CI: 0.73, 0.95). APOE genotype have significant interactions with meat and fish intake (Ps < 0.05). Compared with low fish intake, high fish intake was associated with lower risk of mortality (HR: 0.74, 95% CI: 0.56–0.98) only among the APOE ε4 carriers. High meat intake was significantly associated with higher risks of mortality (HR: 1.13, 95% CI: 1.04–1.25) only among the APOE ε4 non-carriers. The interactive relationship was restricted among the male. No significant findings were observed between egg and mortality among carriers or non-carriers.Conclusions: Among Chinese older adults, the significance of associations of mortality with reported meat or fish intake depended on APOE-E4 carriage status. If validated by other studies, our findings provide evidence for gene-based “precision” lifestyle recommendations.

scholarly journals The Association between Allostatic Load and Mortality among Chinese Older Adults: The Chinese Longitudinal Health and Longevity Study

2020 ◽  
Author(s):  
Tianhang Zhang ◽  
Lijing Yan ◽  
Huashuai Chen ◽  
Haiyu Jin ◽  
Chenkai Wu
Keyword(s):  
Older Adults ◽  
Allostatic Load ◽  
Adverse Outcomes ◽  
Cox Models ◽  
Chinese Older Adults ◽  
Healthy Longevity ◽  
Increased Risk ◽  
Significant Difference ◽  
All Cause Mortality ◽  
Wear And Tear

Abstract Background Allostatic load, as multiple biomarker measures of ‘wear and tear’ on physiological systems, has shown some promise that high burden of AL is associated with increased risk of adverse outcomes, but little attention has been paid to China with largest aging population in the world. This study is to examine the association between allostatic load (AL) and all-cause mortality among Chinese adults aged at least 60 years. Methods Data were from 2,439 participants in the Chinese Longitudinal Healthy Longevity Survey. The final analytic sample consisted of 1,519 participants. Cox models were used to examine the association between AL and mortality among men and women, separately. Analysis were also adjusted for potential confounders including age, ethnicity, education, and marital status, smoking and exercise. Results In the fully adjusted model, males with a medium AL burden (score: 2–4) and high AL burden (score: 5–9) had a 34% and 128% higher hazard of death, respectively, than those with a low AL burden (score: 0–1). We did not find significant difference between females with different levels of AL burden. Discussion Higher AL burden was associated with increased all-cause mortality among Chinese men aged at least 60 years. However, we did not find strong evidence about Allostatic load was associated with specific causes of death over the same follow-up period among women. In conclusion Intervention programs targeting modifiable components of the AL burden may help prolong lifespan for older adults, especially men, in China.

Tooth Loss, Denture Use, and Cognitive Impairment in Chinese Older Adults: A Community Cohort Study

2021 ◽  
Author(s):  
Hai-Lian Yang ◽  
Fu-Rong Li ◽  
Pei-Liang Chen ◽  
Xin Cheng ◽  
Chen Mao ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Confidence Interval ◽  
Tooth Loss ◽  
Potential Interaction ◽  
Hazard Ratio ◽  
Chinese Older Adults ◽  
Healthy Longevity ◽  
Natural Teeth ◽  
State Examination

Abstract Background Evidence regarding the associations of tooth loss and denture use with incident cognitive impairment is inconclusive in older adults, and few prospective studies have examined the potential interaction between tooth loss and denture use in these specific populations. Methods Data were assessed from 17 079 cognitively normal older adults aged ≥65 years, participating in the Chinese Longitudinal Healthy Longevity Survey. The outcome of interest was cognitive impairment (assessed by the Chinese version of Mini-Mental State Examination). The number of natural teeth and status of denture use were collected by a structural questionnaire. Results A total of 6456 cases of cognitive impairment were recorded during 88 627 person-years of follow-up. We found that compared with participants with 20+ teeth, those with 10–19, 1–9, and 0 teeth had increased risks of incident cognitive impairment (p-trend < .001). Participants without dentures also had a higher risk of incident cognitive impairment, compared with those who wore dentures. Effect modification by denture use was observed (p-interaction = .010). Specifically, among those without dentures, the adjusted hazard ratio (95% confidence interval) for participants with 10–19, 1–9, and 0 teeth were 1.19 (1.08, 1.30), 1.28 (1.17, 1.39), and 1.28 (1.16, 1.41), respectively, as compared to those with 20+ teeth. In contrary, among denture users, detrimental effect was only observed among those with 0 teeth (hazard ratio 1.14, 95% confidence interval: 1.16, 1.41). Conclusions In Chinese older adults, maintaining 20+ teeth is important for cognitive health; denture use would attenuate the detrimental effects of tooth loss, especially for partial tooth loss, on cognitive impairment.

scholarly journals DISPARITIES IN DEPRESSION AMONG CHINESE OLDER ADULTS WITH NEURODEGENERATIVE DISEASES

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S879-S879
Author(s):  
Zhichao Hao ◽  
qingyi Li ◽  
Nicole Ruggiano
Keyword(s):  
Older Adults ◽  
Neurodegenerative Diseases ◽  
Incidence Rate ◽  
Research Policy ◽  
Activity Level ◽  
Policy And Practice ◽  
Chinese Older Adults ◽  
Healthy Longevity ◽  
Negative Impacts ◽  
Self Reported Health Status

Abstract Depression is a major health issue among older adults, and it exerts negative impacts on them physically and mentally. In turn, various factors facilitate or impede the occurrence of depression, socially, economically and culturally. At the same time, neurodegenerative diseases have become a leading cause of death and disability worldwide. In China, the incidence rate of Parkinson’s disease among older adults aged 65 and older is 1.7%, which means 100,000 new cases occur each year, more than 2.5 million in total. Meanwhile, 3.21% of incidence rate, more than 8 million older adults aged 65 and older with Alzheimer’s Disease and Related Dementia (AD/RD) makes China become the largest and fastest-growing area of AD/RD in the world. Around 2050, Chinese older adults with AD/RD will exceed 20 million. However, little is known about the extent that to which older adults with Parkinson’s or AD/RD in China will suffer from depression. This study was conducted on the latest wave (2011-2014) of the Chinese Longitudinal Healthy Longevity Survey (CLHLS, 1998-2014). The sample included 334 Chinese older adults aged 65 and older with neurodegenerative diseases (Parkinson’s or AD/RD). A univariate and binomial hierarchical logistic regression were performed. Result showed that 13.5% (n = 45) participants reported depression. Several covariates were significantly correlated with the occurrence of depression, including: co-residence of interviewee, activity level, level of chronic diseases, self-reported health status and Instrumental Activity of Daily Life. Implications for research, policy, and practice are discussed.

Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism, Lower Extremity Strength, and Physical Performance in Older Adults

2019 ◽  
Vol 99 (8) ◽  
pp. 998-1009
Author(s):  
Kurt Shuler ◽  
Joseph F Sucic ◽  
Susan Ann Talley ◽  
Allon Goldberg
Keyword(s):  
Older Adults ◽  
Lower Extremity ◽  
Physical Performance ◽  
Correlation Coefficients ◽  
Interaction Effects ◽  
Converting Enzyme ◽  
Cross Sectional ◽  
Lower Extremity Strength ◽  
Ace Genotype ◽  
And Performance

AbstractBackgroundEvidence for associations between the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene and physical performance is conflicting. Furthermore, investigations of relationships between lower extremity strength and physical performance have usually not considered the role of the ACE genotype, and it is unclear whether there are variations in relationships between lower extremity strength and physical performance among ACE genotypes in older adults.ObjectiveThe objectives of this study were to investigate associations between the ACE I/D polymorphism and physical performance and to determine whether relationships between lower extremity strength and physical performance vary among ACE genotypes in older adults.DesignThis was a cross-sectional observational study.MethodsCommunity-dwelling adults (N = 88) who were at least 60 years old completed physical performance and lower extremity strength tests. After DNA was extracted from saliva, ACE I/D polymorphism genotyping was done. The Spearman rank order correlation coefficient was used to examine associations between lower extremity strength and physical performance within ACE genotype subgroups. Analysis of covariance and linear regression were used to examine ACE genotype and ACE genotype × lower extremity strength interaction effects in relation to physical performance.ResultsGenotype-specific correlation coefficients exhibited substantial variation among ACE genotype subgroups; however, differences did not attain statistical significance. Statistically significant genotype × lower extremity strength interaction effects in relation to physical performance were detected.LimitationsThe cross-sectional design precludes inferring causal relationships between strength and performance. The small sample size contributed to limited power to detect additional interaction effects and to detect statistically significant differences between correlation coefficients among ACE genotype subgroups.ConclusionsThe ACE I/D polymorphism is, interactively with lower extremity strength, associated with physical performance. Genotype-specific correlation coefficients and ACE genotype × lower extremity strength interaction effects on physical performance are consistent with variations in relationships between lower extremity strength and performance among ACE genotype subgroups.

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