Endodontic Therapy and Surgical Excision of a Chronic Suppurative Osteomyelitic Lesion in a Horse: A Case Report

1996 ◽  
Vol 13 (4) ◽  
pp. 145-148 ◽  
Author(s):  
Steven D. Baerg ◽  
David A. Russell ◽  
Laura M. LeVan ◽  
Carl A. Kirker-Head
Keyword(s):  
Eating Habits ◽  
Surgical Excision ◽  
Maxillary Incisor ◽  
Surgical Removal ◽  
Mandibular Incisor ◽  
Surgical Extraction ◽  
History Of ◽  
Functional Position

A 22 year old thoroughbred gelding was presented for evaluation and treatment of chronic dental disease. The horse had a history of quidding and abnormal bit behavior. Intraoral examination revealed signs of chronic generalized gingival inflammation and severe dental caries affecting the maxillary and mandibular incisor teeth. Treatment was provided on two separate visits over an interval of four months. The first visit consisted of the surgical extraction of three unrestorable incisor teeth and restoration of six carious maxillary incisor teeth. The second visit consisted of conventional endodontic therapy on the remaining mandibular incisor teeth and the surgical removal of a chronic suppurative osteomyelitic lesion. Immediate and long term improvements in eating habits were noted. Three month follow-up examinations following completion of treatment have shown the teeth to be in functional position, the restorations intact, and the surgical site well healed.

Extramedullary Plasmacytoma of The Frontal Sinus: A Case Report

FACE ◽  
2021 ◽  
pp. 273250162110536
Author(s):  
Joshua Harrison ◽  
Samantha Marley ◽  
Shawhin Shahriari ◽  
Christian Bowers ◽  
Anil Shetty
Keyword(s):  
Frontal Sinus ◽  
Surgical Excision ◽  
Extramedullary Plasmacytoma ◽  
High Rate ◽  
Solitary Plasmacytoma ◽  
Case Presentation ◽  
Long Term Follow Up ◽  
History Of

We report a rare case of an extramedullary plasmacytoma (EMP) in the frontal sinus with an indolent clinical presentation. Although a history of trauma was absent, the initial diagnosis was a mucocele, based on the radiological findings. Upon surgical excision, the patient was found to have an EMP. EMP, a form of solitary plasmacytoma, has a significantly high rate of conversion to multiple myeloma. This mandates long-term follow-up, even after successful radiotherapy and/or resection. While radiation therapy is generally considered a first line treatment for EMP, surgical intervention may provide optimal treatment in complicated cases. This case presentation highlights the prognosis of patients diagnosed with EMP.

scholarly journals Thirteen-year follow-up of parasellar intravascular papillary endothelial hyperplasia successfully treated by surgical excision: case report

2015 ◽  
Vol 15 (4) ◽  
pp. 384-391 ◽  
Author(s):  
Sook Young Sim ◽  
Yong Cheol Lim ◽  
Keun Soo Won ◽  
Kyung Gi Cho
Keyword(s):  
Surgical Excision ◽  
Subtotal Resection ◽  
Intravascular Papillary Endothelial Hyperplasia ◽  
Long Term Follow Up ◽  
History Of ◽  
Papillary Endothelial Hyperplasia ◽  
The Right ◽  
Frontal Skull Base

Intracranial intravascular papillary endothelial hyperplasia (IPEH) is very rare, and to our knowledge long-term follow-up results have not been previously published. An 11-year-old boy presented with a 6-month history of progressive visual impairment in the right eye. Magnetic resonance imaging revealed a well-enhanced, large parasellar mass involving the cavernous sinus, right frontal skull base, and ethmoid and sphenoid sinuses. Frontotemporal craniotomy and subtotal resection were performed, and the diagnosis of IPEH was confirmed. The mass increased in size during the following 3 months. A second operation was performed via frontotemporal craniotomy combined with a transsphenoidal approach, and gross-total resection of the tumor was achieved. Adjuvant radiotherapy (5040 cGy) and chemotherapy with interferon were administered. The patient's visual symptoms improved, and there was no recurrence during a 13-year follow-up period. The results of this case indicate that intracranial IPEH can recur with subtotal resection; however, optimal resection with multimodal adjuvant treatment can control the disease for many years, if not permanently.

Natural History of Adult-Onset Laryngeal Papillomatosis following Multiple Cidofovir Injections

2006 ◽  
Vol 115 (3) ◽  
pp. 175-181 ◽  
Author(s):  
Ana Nusa Naiman ◽  
Darius Abedipour ◽  
Sonia Ayari ◽  
Elizabeth Fresnel ◽  
Bruno Coulombeau ◽  
...  
Keyword(s):  
Complete Remission ◽  
Surgical Excision ◽  
Intralesional Injection ◽  
Adult Onset ◽  
Laryngeal Papillomatosis ◽  
Long Term Follow Up ◽  
History Of ◽  
A Prospective Study

Objectives: A prospective study was performed to assess the intermediate and long-term efficacy of intralesional cidofovir therapy associated with surgical excision in laryngeal papillomatosis in adults. Methods: Endoscopy with intralesional injection of cidofovir 5 mg/mL was performed 3 times at 4-week intervals. The concentration was later increased to 7.5 mg/mL and the interval between injections shortened to 2 weeks. Further treatment was performed at 3 or 6 months, depending on the evolution of the papillomas. After complete remission, the treatment was stopped and the patients were reviewed every 6 months. Results: Nineteen patients completed the protocol, with a mean of 4.5 injections each. Complete remission was obtained in 17 cases (89%) after a mean of 3.8 procedures. Remission was stable after a mean follow-up of 24 months (range, 8 to 57 months). With higher cidofovir concentrations at shorter intervals, patients needed fewer injections to achieve remission (mean, 2.1 versus 4.7 injections). Conclusions: The effectiveness of intralesional cidofovir therapy in adult-onset recurrent respiratory papillomatosis was impressive. Once obtained, complete remission was stable on intermediate or long-term follow-up. The concentration and the interval between injections seemed to influence the number of injections necessary to achieve remission.

scholarly journals A Rare Case of Giant Mesenteric Lipoblastoma in a 6-Year-Old Child and Review of the Literature

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Maria Enrica Miscia ◽  
Gabriele Lisi ◽  
Giuseppe Lauriti ◽  
Angela Riccio ◽  
Dacia Di Renzo ◽  
...  
Keyword(s):  
Benign Tumor ◽  
Malignant Tumors ◽  
Surgical Excision ◽  
Review Of The Literature ◽  
Imaging Studies ◽  
Long Term Follow Up ◽  
Rare Benign Tumor ◽  
History Of

Giant mesenteric lipoblastoma is a rare benign tumor arising from the adipocytes. It can mimic malignant tumors, and its diagnosis is difficult before surgery. Imaging studies could lead the diagnosis but not confirm it. Those tumors arising in the abdomen are usually larger and can cause symptoms of compression. Surgical excision is the treatment of choice, and a long-term follow-up is necessary to detect local recurrences. Only a few cases of lipoblastomas arising from the mesentery are reported in literature. We present a case of a rare giant lipoblastoma arising from the mesentery of a 6-year-old girl, with a history of postprandial abdominal pain.

MRI findings and surgical treatment of a carpal synovial cyst in a dog

2020 ◽  
Vol 8 (2) ◽  
pp. e001059
Author(s):  
Caitlin Tzounos ◽  
Olivier Taeymans ◽  
Rob Quinn ◽  
Georg Haimel
Keyword(s):  
Clinical Signs ◽  
Surgical Excision ◽  
Synovial Cyst ◽  
Joint Space ◽  
Mri Findings ◽  
Thoracic Limb ◽  
History Of ◽  
Mri Characteristics

A male neutered pug aged 3 years and 3 months presented with a 4-month history of persistent left thoracic limb lameness, which was associated with a firm swelling on the palmerolateral aspect of the carpus. MRI confirmed a fluid-filled structure, which appeared to be associated with the joint space. The structure was surgically excised. Histopathology confirmed a true synovial cyst. Follow-up by telephone and email with the owner 18 months after surgery confirmed the patient was clinically well, with complete resolution of the lameness and no recurrence of swelling. This report discusses the MRI characteristics and successful treatment of a carpal synovial cyst causing lameness in the absence of osteoarthritis. There was long-term resolution of clinical signs with surgical excision of the cyst.

scholarly journals Fracture of the anconeal process in two cats

2010 ◽  
Vol 23 (02) ◽  
pp. 124-127 ◽  
Author(s):  
K. Hurter ◽  
N. Medl
Keyword(s):  
Clinical Outcome ◽  
Radiographic Evaluation ◽  
Surgical Removal ◽  
Bony Avulsion ◽  
History Of

SummaryTwo adult Domestic Shorthaired cats were presented with acute forelimb lameness. In one case, there was a history of trauma. A fracture of the anconeal process was diagnosed on the flexed mediolateral radiographs of the elbow in both cats. The fracture was accompanied by a bony avulsion of the tricipital tendon in one animal. Both cats underwent surgical removal of the fractured anconeal process. Follow-up radiographic evaluation was available for one cat six months after treatment; radiographs showed evidence of osteoarthritis. The long-term clinical outcome, based on owner telephone follow-up conducted four and nine years postoperatively, was considered to be satisfactory.

scholarly journals MULTIPLE SURGERIES AND LONG-TERM ENDOCRINE FOLLOW-UP IN MEN 2A SYNDROME

2015 ◽  
Vol 2 (4) ◽  
pp. 204-209
Author(s):  
Rene Baloescu ◽  
Mara Carsote ◽  
Simona Elena Albu ◽  
Ana Valea
Keyword(s):  
Large Family ◽  
Surgical Removal ◽  
Gene Testing ◽  
Endocrine Profile ◽  
History Of ◽  
Partial Thyroidectomy ◽  
One Year ◽  
Close Relatives

MEN2A (Multiple Endocrine Neoplasia type 2) syndrome, an autosomal dominant condition, requires multiple surgeries in order to prevent or treat different tumours that are related to RET proto-oncogene mutations. Early intervention is most useful in cases with prior genetic confirmation. This is a case report presenting a long medical history of a female suffering of MEN2A syndrome. A 44-year-old woman, with a large family history of different endocrine cancers but no gene testing, is diagnosed at the age of 31 with a thyroid nodule of 1.7 centimeters (cm) which is removed by a partial thyroidectomy. Medullary thyroid cancer (MTC) is confirmed and calcitonin is found high. Total thyroidectomy is performed without consecutive normalization of calcitonin and secondary persistent post-operatory hypoparathyroidism. 6 months later a right laparoscopic adrenalectomy is performed for a pheochromocytoma (Pheo) of 5.2 cm. Despite normal levels of metanephrines and normetanephrines, a left adrenal tumor of 1.5 cm is discovered one year later. One decade later, the blood calcitonin progressively increased and 41 lymph nodes from latero-cervical areas and central neck compartment were removed. 14 of them had MTC metastases. 8 months later, typical endocrine profile suggested a Pheo and laparoscopic left adrenalectomy is performed with chronic adrenal insufficiency needing lifelong hydrocortisone and fludrocortisone replacements. The MEN2A syndrome-related multiple surgeries are correlated with long-term endocrine follow-up in challenging cases such as ours requiring a multi-disciplinary approach. The lack of gene mutation identification during childhood or at close relatives delays the diagnosis and thus the potential curative surgical removal of the thyroid and adrenal tumours with a more severe prognosis.

The natural history of pituitary apoplexy: long term follow-up study

2019 ◽  
Author(s):  
Ayesha Shaikh ◽  
Natasha Shrikrishnapalasuriyar ◽  
Giselle Sharaf ◽  
David Price ◽  
Maneesh Udiawar ◽  
...  
Keyword(s):  
Natural History ◽  
Pituitary Apoplexy ◽  
Follow Up Study ◽  
Long Term Follow Up ◽  
History Of

Long-term systolic blood pressure and all-cause mortality in heart failure with preserved ejection fraction: an analysis of the TOPCAT trial

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
P Huang ◽  
C Liu
Keyword(s):  
Heart Failure ◽  
Blood Pressure ◽  
Ejection Fraction ◽  
Funding Source ◽  
Preserved Ejection Fraction ◽  
Risk Of Mortality ◽  
All Cause Mortality ◽  
History Of

Abstract Background Lower systolic blood pressure (SBP) at admission or discharge was associated with poor outcomes in patients with heart failure and preserved ejection fraction (HFpEF). However, the optimal long-term SBP for HFpEF was less clear. Purpose To examine the association of long-term SBP and all-cause mortality among patients with HFpEF. Methods We analyzed participants from the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) study. Participants had at least two SBP measurements of different times during the follow-up were included. Long-term SBP was defined as the average of all SBP measurements during the follow-up. We stratified participants into four groups according to long-term SBP: <120mmHg, ≥120mmHg and <130mmHg, ≥130mmHg and <140mmHg, ≥140mmHg. Multivariable adjusted Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CI) for all-cause mortality associated with SBP level. To assess for nonlinearity, we fitted restricted cubic spline models of long-term SBP. Sensitivity analyses were conducted by confining participants with history of hypertension or those with left ventricular ejection fraction≥50%. Results The 3338 participants had a mean (SD) age of 68.5 (9.6) years; 51.4% were women, and 89.3% were White. The median long-term SBP was 127.3 mmHg (IQR 121–134.2, range 77–180.7). Patients in the SBP of <120mmHg group were older age, less often female, less often current smoker, had higher estimated glomerular filtration rate, less often had history of hypertension, and more often had chronic obstructive pulmonary disease and atrial fibrillation. After multivariable adjustment, long-term SBP of 120–130mmHg and 130–140mmHg was associated with a lower risk of mortality during a mean follow-up of 3.3 years (HR 0.65, 95% CI: 0.49–0.85, P=0.001; HR 0.66, 95% CI 0.50–0.88, P=0.004, respectively); long-term SBP of <120mmHg had similar risk of mortality (HR 1.03, 95% CI: 0.78–1.36, P=0.836), compared with long-term SBP of ≥140mmHg. Findings from restricted cubic spline analysis demonstrate that there was J-shaped association between long-term SBP and all-cause mortality (P=0.02). These association was essentially unchanged in sensitivity analysis. Conclusions Among patients with HFpEF, long-term SBP showed a J-shaped pattern with all-cause mortality and a range of 120–140 mmHg was significantly associated with better outcomes. Future randomized controlled trials need to evaluate optimal long-term SBP goal in patients with HFpEF. Funding Acknowledgement Type of funding source: Foundation. Main funding source(s): China Postdoctoral Science Foundation Grant (2019M660229 and 2019TQ0380)

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