Breastfeeding, Body Mass Index, Asthma and Atopy in Children

2003 ◽  
Vol 15 (1_suppl) ◽  
pp. S15-S17 ◽  
Author(s):  
WH Oddy ◽  
JL Sherriff

The objective of this study was to determine the relationship between breastfeeding, asthma and atopy, and any influence of child body mass index (BMI). Prospective birth cohort data were used to model the association between breastfeeding duration, BMI, asthma and atopy in children at six years. After adjustment for BMI and associated covariates, breastfeeding (per additional month of feeding) was marginally associated with decreased BMI ( p=0.083). BMI was significantly associated with current asthma ( p=<0.0005) and atopy ( p=0.055). Exclusive breastfeeding for less than four months was a risk for current asthma ( p=0.033) and atopy ( p=0.005). The early introduction of formula leads to an increase in child BMI and early asthma and atopy. Increased BMI is a risk factor for childhood asthma and atopy. These findings suggest that public health interventions to optimise breastfeeding duration and reduce overweight in children may help attenuate the community burden of wheezing illness early in life.

Nutrients ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 1751 ◽  
Author(s):  
Janina Eichler ◽  
Ricarda Schmidt ◽  
Tanja Poulain ◽  
Andreas Hiemisch ◽  
Wieland Kiess ◽  
...  

(1) Background: Parental feeding practices are related to child body mass index (BMI, kg/m2) and seem to be a consequence rather than cause of child BMI, but research so far is limited. Stability and continuity of feeding practices, probably explaining changes in food intake and child BMI, remain to be poorly examined. (2) Methods: Feeding practices (i.e., restriction, food as reward, pressure to eat, monitoring) assessed via the Child Feeding Questionnaire, child age, standardized BMI (zBMI), and socio-economic status were measured annually at multiple visits (range 2–8) in a population-based longitudinal cohort study of 1512 parents with their children aged 2 to 12 years. Stability, continuity, and bi-directionality of feeding practices and child zBMI were calculated using correlation coefficients, paired t tests, and cross-lagged panels, respectively. (3) Results: Feeding practices and child zBMI showed moderate to high stability. While continuity was high for restriction, minor temporal changes were observed for other feeding practices and child zBMI. Cross-lags indicated that child zBMI predicted restriction, pressure to eat, and monitoring, while food-rewarding predicted child zBMI only minorly. (4) Conclusions: Parents seem to adapt feeding practices to child zBMI with the exception of food-rewarding.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Charlotte V. Farewell ◽  
Ryley Donohoe ◽  
Zaneta Thayer ◽  
James Paulson ◽  
Jacinda Nicklas ◽  
...  

Abstract Background Perinatal (antenatal and postpartum) depression impacts approximately 12% of mothers. Perinatal depression can impact everyday functioning for mothers, and the relationship with, and development of, their children. The purpose of this study was to investigate depression trajectories from the antenatal period through 54-months postpartum and associations with child body mass index at 54-months postpartum. Methods This study applied latent growth modeling to the Growing Up in New Zealand study, which is a longitudinal pregnancy cohort study that provides nationally representative-level data, to investigate associations between depression at three time points (antenatal, 9-months postpartum, 54-months postpartum) and child body mass index at 54-months (n=4897). Results The average slope of depression for this sample is low and decreases over time. When child BMI was added to the model as an outcome variable, both antenatal depression (B=.25, p<.01), and the rate of change of depression across the perinatal and postpartum periods (B=.09, p<.01) were associated with child BMI at 54-months postpartum. After controlling for sociodemographic characteristics, antenatal depression, but not the slope of depression, remained significantly associated with child BMI (B=.05, p<.05). When controlling for maternal pre-pregnancy BMI the effect of antenatal depression on child BMI at 54-months was entirely attenuated (χ2 (9) = 39.60, p < .05, SRMR = 0.01, CFI = .99, RMSEA = 0.03, BIC=53213). Conclusions Our findings align with the Developmental Origins of Health and Disease theory and imply that both the physical and mental health of mothers during pregnancy may be important indicators of child growth and development outcomes. Early intervention directed towards women who have even mild depression scores during pregnancy may promote healthy child development outcomes. Additionally, given the heterogeneity of depressive symptoms over time seen in this study, multiple assessment periods across the postpartum period may be valuable to adequately address and support maternal mental health.


2021 ◽  
Author(s):  
Charlotte V. Farewell ◽  
Ryley Donohoe ◽  
Zaneta Thayer ◽  
James Paulson ◽  
Jacinda Nicklas ◽  
...  

Abstract Background: Perinatal (antenatal and postpartum) depression impacts approximately 12% of mothers. Perinatal depression can impact everyday functioning for mothers, and the relationship with, and development of, their children. The purpose of this study was to investigate depression trajectories from the antenatal period through 54-months postpartum and associations with child body mass index at 54-months postpartum.Methods: This study applied latent growth modeling to the Growing Up in New Zealand study, which is a longitudinal pregnancy cohort study that provides nationally representative level data, to investigate associations between depression at three time points (antenatal, 9-months postpartum, 54-months postpartum) and child body mass index at 54-months (n=4897).Results: The average slope of depression for this sample is low and decreases over time. When child BMI was added to the model as an outcome variable, both antenatal depression (B=.25, p<.01), and the rate of change of depression across the perinatal and postpartum periods (B=.09, p<.01) were associated with child BMI at 54-months postpartum. After controlling for sociodemographic characteristics, antenatal depression, but not postnatal depression, remained significantly associated with child BMI (B=.05, p<.05). When controlling for maternal pre-pregnancy BMI the effect of antenatal depression on child BMI at 54-months was entirely attenuated (χ² (9) = 39.60, p < .05, SRMR = 0.01, CFI = .99, RMSEA = 0.03, BIC=53213).Conclusions: Our findings align with the Developmental Origins of Health and Disease theory and imply that both the physical and mental health of mothers during pregnancy may be important indicators of child growth and development outcomes. Early intervention directed towards women who have even mild depression scores during pregnancy may promote healthy child development outcomes. Additionally, given the heterogeneity of depressive symptoms over time seen in this study, multiple assessment periods across the postpartum period may be valuable to adequately address and support maternal mental health.


2019 ◽  
Vol 19 (1) ◽  
pp. 167-171
Author(s):  
Mary Jane Botabara-Yap ◽  
Miriam R. Estrada ◽  
Edwin Balila

The epidemic of overweight is encroaching in the world today, irrespective of economic and social status and regions. It is now seen as a public health threat and one that must be taken seriously in all aspects of public health interventions. There is a need to deeper understand the relationship of lifestyle behaviors and the epidemic of overweight and obesity. This cross-sectional study investigates the lifestyle predictors (smoking, physical activity, diet, and sleeping) of overweight as measured by body mass index (BMI) and waist-to-hip ratio (WHR). A questionnaire survey was conducted among 459 samples (18 years old and above) from those who attended a health screening drive, conducted in three major regions in Peninsular Malaysia. Data were analyzed using descriptive statistics as well as regression model, with p<0.05 considered significant. The overall Body Mass Index (BMI) of the population was overweight at 24.69 while the Waist-to-Hip ratio (WHR) for female was 0.86, classified as high and for male, 0.94 which was borderline. Predictor model revealed that smoking (P<0.05, R2 - 0.38) and physical activity (P=0.02, R2 - 0.11) were predictors for body mass index while smoking P<0.05, R2 - 0.50) was a predictor of Waist-to-hip ratio. Findings showed that the problem of overweight in Malaysia is real and smoking and physical activity play a strong role and need to be considered in any public health interventions.


2015 ◽  
Vol 1 (2) ◽  
pp. 00026-2015 ◽  
Author(s):  
Melanie C. Matheson ◽  
John A. Burgess ◽  
Melisa Y.Z. Lau ◽  
Adrian J. Lowe ◽  
Lyle C. Gurrin ◽  
...  

Epidemiological data on asthma suggest a sex difference that varies with age. Hormonal effects have been suggested as a possible explanation for these differences but there is a scarcity of evidence on these relationships. Our objective was to examine the relationship between reproductive factors and asthma risk among females and to examine whether body mass index (BMI) modifies this relationship.Female participants in the 2004 fifth decade follow-up postal survey of the Tasmanian Longitudinal Health Study formed the study population. Reproductive history and data on hormonal contraceptive (HC) use were collected on 2764 females. Multiple logistic regression was used to assess the association between the reproductive factors and current asthma.The mean age of participants was 43 years and the prevalence of middle-aged current asthma was 12.8%. Females with very early menarche (≤10 years) had higher odds of middle-aged current asthma (OR 1.91, 95% CI 1.14–3.2). Pregnancy history (number of births and age at first pregnancy) were not associated with current asthma risk at 44 years. Ever having used HCs, years of use and age started using HCs were not individually associated with current asthma risk. However, body mass index significantly modified the relationship between HC use and asthma. We found increasing years of pill use was associated with a significantly increased risk of current asthma in overweight/obese women but a reduced risk in normal weight women (interaction p=0.015).Hormonal effects from use of HCs and early menarche may contribute to the sex differential in asthma risk. Our findings suggest that in obese women with a history of long-term HC use may be at an increased risk of chronic respiratory disease, and regular monitoring for asthma and asthma symptoms may be recommended.


Nutrients ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 1883 ◽  
Author(s):  
Chad A. Logan ◽  
Linda P. Siziba ◽  
Wolfgang Koenig ◽  
Prudence Carr ◽  
Hermann Brenner ◽  
...  

The objective of the study was to investigate the potential association of human milk leptin concentrations with child body mass index (BMI) and BMI trajectory patterns up to two years of age among children in the Ulm SPATZ Health Study. Leptin concentration was measured in skimmed human milk by ELISA (R&D System). Child BMI was determined at two to three days, three to four weeks, four to five months, one year, and two years of age. In SPATZ, leptin concentration at six weeks was inversely associated with child BMI at four to five weeks [beta –0.13, 95%CI –0.21;–0.05)] and at three to four months –0.12 –0.21;–0.03)]. Among infants of average BMI shortly after delivery, six week leptin was positively associated with greater increase in BMI from four to five weeks up to two years of age [0.16 (0.04;0.27)]. No associations were observed for six month leptin. Direction of association was the same in the Ulm Birth Cohort Study (UBCS), but statistically insignificant as the point estimate included the null effect value. Our results from SPATZ suggest human milk leptin may play a role in early infant growth. However, it is plausible that the lack of associations in UBCS suggest that these differences of human milk leptin composition between populations could have an impact in infant growth and development in a given population.


1970 ◽  
Vol 25 (1) ◽  
pp. 9-13
Author(s):  
S Jahan ◽  
TR Das ◽  
KB Biswas

Background and Aims: Cord blood leptin may reflect the leptinemic status of a newborn at birth more accurately than the leptin values of blood collected from other sites. The present study was undertaken to determine the relationship of cord serum leptin concentration at birth with neonatal and maternal anthropometric parameters. Materials and Methods: Blood was taken from the umbilical cord of the babies at delivery. Maternal anthropometric measurements were recorded at admission for delivery. Neonatal anthropometric measurements were recorded within 48 hours after delivery. Linear regression analysis was used to explore the relationship between cord serum leptin concentration and anthropometric parameters of the baby and the mother. Both Serum leptin and serum C-peptide levels were measured by chemiluminescence-based ELISA method. Results: The leptin concentration (ng/ml, mean±SD) in cord blood was 39.13±14.44. Cord leptin levels correlated with birth weight (r=0.673, p<0.0001), ponderal index (r=0.732, p<0.0001) but it did not correlate with maternal body mass index, gestational age (r=0.135, p=0.349) at delivery or cord serum C-peptide concentration (r=-0.049, p=0.735) or placental weight (r=0.203, p=0.157). Conclusion: There are associations between cord leptin concentration at delivery and birth weight, ponderal index (PI) of the babies but not body mass index (BMI) of the mothers. High leptin levels of the baby could represent an important feedback modulator of substrate supply and subsequently for adipose tissue status during late gestation. (J Bangladesh Coll Phys Surg 2007; 25 : 9-13)


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