Illness Identity and the Self-regulatory Model in Recovery from Early Stage Gynaecological Cancer

2001 ◽  
Vol 6 (5) ◽  
pp. 511-521 ◽  
Author(s):  
E. J. Bradley ◽  
E. Calvert ◽  
M. K. Pitts ◽  
C. W. E. Redman
Keyword(s):  
Early Stage ◽  
The Self ◽  
Gynaecological Cancer ◽  
Illness Identity ◽  
Regulatory Model

Observing patient-provider interaction as guided by the self-regulatory model of illness

2002 ◽  
Author(s):  
N. C. M. Theunissen ◽  
D. T. D. de Ridder ◽  
A. M. van Dulmen
Keyword(s):  
The Self ◽  
Regulatory Model

scholarly journals Effects of GnRH immunization on the reproductive axis and thymulin

2015 ◽  
Vol 226 (2) ◽  
pp. 93-102 ◽  
Author(s):  
Shiping Su ◽  
Xiaoxia Sun ◽  
Xiuhong Zhou ◽  
Fuigui Fang ◽  
Yunsheng Li
Keyword(s):  
Early Stage ◽  
Feedback Regulation ◽  
Reproductive Hormones ◽  
The Self ◽  
Endocrine Function ◽  
Dependent Manner ◽  
Hpg Axis ◽  
Bidirectional Regulation ◽  
Repressive Effect

The bidirectional regulation of thymulin in the reproductive-endocrine function of the hypothalamic–pituitary–gonadal (HPG) axis of rats immunized againstGnRHremains largely unclear. We explored the alterations in hormones in the HPG axis in immunized rats to dissect the repressive effect of immunization on thymulin, and to clarify the interrelation of reproductive hormones and thymulinin vivo. The results showed that, in the first 2 weeks of booster immunization, thymulin was repressed when reproductive hormones were severely reduced. The self-feedback regulation of thymulin was then stimulated in later immune stages: the rising circulating thymulin upregulated LH and FSH, including GnRH in the hypothalamus, although the levels of those hormones were still significantly lower than in the control groups. In astrocytes, thymulin produced a feedback effect in regulated GnRH neurons. However, in the arcuate nucleus (Arc) and the median eminence (ME), the mediator of astrocytes and other glial cells were also directly affected by reproductive hormones. Thus, in immunized rats, the expression of glial fibrillary acidic protein was distinctly stimulated in the Arc and ME. This study demonstrated that thymulin was downregulated by immunization againstGnRHin early stage. Subsequently, the self-feedback regulation was provoked by low circulating thymulin. Thereafter, rising thymulin levels promoted pituitary gonadotropins levels, while acting directly onGnRHneurons, which was mediated by astrocytes in a region-dependent manner in the hypothalamus.

Obesity and gynaecological cancer

2008 ◽  
Vol 14 (1) ◽  
pp. 33-37 ◽  
Author(s):  
Geoffrey Lane
Keyword(s):  
Early Stage ◽  
Squamous Carcinoma ◽  
Later Life ◽  
Gynaecological Cancer ◽  
Obese Women ◽  
Early Stage Disease ◽  
Global Epidemic ◽  
Stage Disease ◽  
Vulval Cancer ◽  
Few Data

Obesity is now considered to be a global epidemic. The problem of obesity has significant implications for the diagnosis and treatment of gynaecological cancer. The cancer most frequently associated with obesity is that of the endometrium. The risk of endometrial cancer is 2–3 times higher in overweight and obese women. Obesity also adversely affects survival in most studies. With regard to ovarian cancer the evidence is inconsistent. Obesity in young adulthood may be more important than that in later life. With regard to survival obesity has an adverse effect but not in early stage disease. Few data are available regarding cervical cancer and obesity. There is evidence that obesity is associated with adenocarcinoma rather than squamous carcinoma. Data on vulval cancer and obesity are scant.

Monitoring the Early Stage Self-Assembly of Enzyme-Assisted Peptide Hydrogels

2013 ◽  
Vol 66 (5) ◽  
pp. 572 ◽  
Author(s):  
Richard J. Williams ◽  
James Gardiner ◽  
Anders B. Sorensen ◽  
Silvia Marchesan ◽  
Roger J. Mulder ◽  
...  
Keyword(s):  
1H Nmr ◽  
Self Assembly ◽  
Early Stage ◽  
The Self ◽  
Spectroscopic Techniques ◽  
Subsequent Formation ◽  
Self Assembling ◽  
Hydrogel Formation ◽  
Assembly Kinetics ◽  
Peptide Hydrogels

The early stages of the self-assembly of peptide hydrogels largely determine their final material properties. Here we discuss experimental methodologies for monitoring the self-assembly kinetics which underpin peptide hydrogel formation. The early stage assembly of an enzyme-catalysed Fmoc-trileucine based self-assembled hydrogel was examined using spectroscopic techniques (circular dichroism, CD, and solution NMR) as well as chromatographic (HPLC) and mechanical (rheology) techniques. Optimal conditions for enzyme-assisted hydrogel formation were identified and the kinetics examined. A lag time associated with the formation and accumulation of the self-assembling peptide monomer was observed and a minimum hydrogelator concentration required for gelation was identified. Subsequent formation of well defined nano- and microscale structures lead to self-supporting hydrogels at a range of substrate and enzyme concentrations. 1H NMR monitoring of the early self-assembly process revealed trends that were well in agreement with those identified using traditional methods (i.e. HPLC, CD, rheology) demonstrating 1H NMR spectroscopy can be used to non-invasively monitor the self-assembly of peptide hydrogels without damaging or perturbing the system.

Brain injury beliefs, self-awareness, and coping: A preliminary cluster analytic study based within the self-regulatory model

2010 ◽  
Vol 20 (6) ◽  
pp. 899-921 ◽  
Author(s):  
Andrew R. Medley ◽  
Theresa Powell ◽  
Andrew Worthington ◽  
Gagandeep Chohan ◽  
Chris Jones
Keyword(s):  
Brain Injury ◽  
The Self ◽  
Analytic Study ◽  
Self Awareness ◽  
Cluster Analytic ◽  
Regulatory Model ◽  
And Coping

scholarly journals Philosophical pedagogy as critics and self- critics: german experience

Osvitolohiya ◽  
2017 ◽  
pp. 44-51
Author(s):  
Maria Kultayeva ◽  
Keyword(s):  
Mass Culture ◽  
Political Ideology ◽  
Early Stage ◽  
Social Systems ◽  
The State ◽  
The Self ◽  
Modern Education ◽  
Education Theory ◽  
The Guardian ◽  
Research Show

In the article are regarded some evolutional tendencies of philosophical pedagogy in the German theoretical tradition. The turn from the normative theories to functional-structuring ones is analyzed on the factual material of Neo-Hegelianism (E. Spranger, T. Litt) and on Adorno’s half-education theory, where the half-education is represented as a form of educational alienation und contributes its conversion to anti-education. One of the alternative theoretical variants proposed by A. Tremlis deduced from theory of the self-referent social systems. Is showed that critics and self-critics of different philosophical and pedagogical constructs is giving impulses for development of philosophical pedagogy as a reflection of the inside logic of learning and educational practices including the claims of globalization. Despite numerous publications devoted to the problem of philosophical and pedagogical comprehension of the challenges of globalization that education is challenged with, the issue is still at an early stage. Nevertheless, the analysis shows that it has already made a certain contribution to the study of real and possible pathologies for the development of modern education. The findings of the research show that the reflection of the state and problems of education in philosophical pedagogy is, at the same time, always a test of the ability of pedagogical theories to fulfill their general civilization function. The activation of its ability to self-criticism is required to cope with that. Without the above mentioned factor, it can easily integrate into political ideology or adapt to the demands of the mass culture, turning from the guardian of the humanistic potential of education into its academically trained destroyer.

scholarly journals Neuronal Signatures of Negative and Positive Schemas towards the Self and Others in Patients with Early Stage Schizophrenia

2021 ◽  
Author(s):  
Jie Shen ◽  
Guangfan Shen ◽  
Woo-Sung Kim ◽  
Uyanga Tsogt ◽  
Congcong Liu ◽  
...  
Keyword(s):  
Early Stage ◽  
The Self ◽  
Positive Schemas

scholarly journals Critica Literară Românească Din Perspectiva Metodelor De Analiză Autocolonială (1840-1939)

2019 ◽  
Vol 20 (1) ◽  
pp. 1-12
Author(s):  
David Morariu
Keyword(s):  
Early Stage ◽  
The Self ◽  
Economic Report ◽  
The West ◽  
Central Concept ◽  
Critical Discourses ◽  
The Way

AbstractThis study aims to analyze the Romanian critical discourses of the second half of the 19th century and especially of the first half of the 20th century, starting from the central concept of “self-colonization”, coined by Alexander Kiossev. The article opens with the conceptual delimiting of the phenomenon imposed by the Bulgarian theoretician and with the hypothesis that Romanian culture can be attributed to self-colonizing cultures. The demonstration of this hypothesis consists of three arguments. The critical discourses belonging to G. Ibrăileanu, E. Lovinescu and C. Dobrogeanu-Gherea highlight, firstly, some of the characteristics of this self-subordination relation. The way the first two emphasize the role of imitation, the necessity of adopting the foreign models and the way Gherea treats the dependence upon the West under an economic report, represent, briefly, the center of the first part of the demonstration. The second one brings to the fore Mihail Kogălniceanu and Titu Maiorescu’s profiles, their discourses being characterized by clumsiness and flaws so typical for a culture found in an early stage of its development. The last argument broadens the scope of the demonstration in the sense that the analysis focuses on social and economic delimiting. The purpose of this delimiting is to establish which are the areas that are more responsive to the manifestation of the self-colonizing phenomenon.

scholarly journals Transition from Self-Organized Criticality into Self-Organization during Sliding Si3N4 Balls against Nanocrystalline Diamond Films

Entropy ◽  
2019 ◽  
Vol 21 (11) ◽  
pp. 1055
Author(s):  
Bogatov ◽  
Podgursky ◽  
Vagiström ◽  
Yashin ◽  
Shaikh ◽  
...  
Keyword(s):  
Friction Force ◽  
Power Law ◽  
Early Stage ◽  
Nanocrystalline Diamond ◽  
The Self ◽  
Self Organization ◽  
Power Law Distribution ◽  
Reciprocating Sliding ◽  
Self Organized ◽  
Self Organized Criticality

The paper investigates the variation of friction force (Fx) during reciprocating sliding tests on nanocrystalline diamond (NCD) films. The analysis of the friction behavior during the run-in period is the focus of the study. The NCD films were grown using microwave plasma-enhanced chemical vapor deposition (MW-PECVD) on single-crystalline diamond SCD(110) substrates. Reciprocating sliding tests were conducted under 500 and 2000 g of normal load using Si3N4 balls as a counter body. The friction force permanently varies during the test, namely Fx value can locally increase or decrease in each cycle of sliding. The distribution of friction force drops (dFx) was extracted from the experimental data using a specially developed program. The analysis revealed a power-law distribution f-µ of dFx for the early stage of the run-in with the exponent value (µ) in the range from 0.6 to 2.9. In addition, the frequency power spectrum of Fx time series follows power-law distribution f-α with α value in the range of 1.0–2.0, with the highest values (1.6–2.0) for the initial stage of the run-in. No power-law distribution of dFx was found for the later stage of the run-in and the steady-state periods of sliding with the exception for periods where a relatively extended decrease of coefficient of friction (COF) was observed. The asperity interlocking leads to the stick-slip like sliding at the early stage of the run-in. This tribological behavior can be related to the self-organized criticality (SOC). The emergence of dissipative structures at the later stages of the run-in, namely the formation of ripples, carbonaceous tribolayer, etc., can be associated with the self-organization (SO).

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