Perceived Risk of Developing Diabetes in Early Adulthood: Beliefs about Inherited and Behavioral Risk Factors across the Life Course

2011 ◽  
Vol 17 (2) ◽  
pp. 285-296 ◽  
Author(s):  
Justin B. Dickerson ◽  
Matthew Lee Smith ◽  
Erica Sosa ◽  
E. Lisako McKyer ◽  
Marcia G. Ory
2019 ◽  
pp. 34-49
Author(s):  
Kristin Litzelman

Although caregivers are often thought of as middle-aged or older adults, cancer caregiving spans the life course. This chapter discusses the unique challenges of cancer caregiving across the life course—early adulthood (18–44 years of age); middle age (45–64 years); and older age (adults 65 years and older)—using data from the 2015 Behavioral Risk Factor Surveillance System and evidence from the extant literature. More than 4 in 10 cancer caregivers were in early adulthood. Another 4 in 10 were in middle age, and nearly 2 in 10 were in older adulthood. Normative developmental patterns differ at each life stage, with implications for supporting cancer caregivers in clinical and policy settings. Future research embracing a nuanced view of caregiving across the life course and across relationship type will enhance the ability to care for caregivers and improve cancer survivor and caregiver well-being.


Neurology ◽  
2021 ◽  
Vol 96 (17) ◽  
pp. e2212-e2219
Author(s):  
Kristine Yaffe ◽  
Eric Vittinghoff ◽  
Tina Hoang ◽  
Karen Matthews ◽  
Sherita H. Golden ◽  
...  

ObjectiveCardiovascular risk factors (CVRFs) are associated with increased risk of cognitive decline, but little is known about how early adult CVRFs and those across the life course might influence late-life cognition. To test the hypothesis that CVRFs across the adult life course are associated with late-life cognitive changes, we pooled data from 4 prospective cohorts (n = 15,001, ages 18–95).MethodsWe imputed trajectories of body mass index (BMI), fasting glucose (FG), systolic blood pressure (SBP), and total cholesterol (TC) for older adults. We used linear mixed models to determine the association of early adult, midlife, and late-life CVRFs with late-life decline on global cognition (Modified Mini-Mental State Examination [3MS]) and processing speed (Digit Symbol Substitution Test [DSST]), adjusting for demographics, education, and cohort.ResultsElevated BMI, FG, and SBP (but not TC) at each time period were associated with greater late-life decline. Early life CVRFs were associated with the greatest change, an approximate doubling of mean 10-year decline (an additional 3–4 points for 3MS or DSST). Late-life CVRFs were associated with declines in early late life (<80 years) but with gains in very late life (≥80 years). After adjusting for CVRF exposures at all time periods, the associations for early adult and late-life CVRFs persisted.ConclusionsWe found that imputed CVRFs across the life course, especially in early adulthood, were associated with greater late-life cognitive decline. Our results suggest that CVRF treatment in early adulthood could benefit late-life cognition, but that treatment in very late life may not be as helpful for these outcomes.


2021 ◽  
pp. 174569162198924
Author(s):  
Annelise A. Madison ◽  
M. Rosie Shrout ◽  
Megan E. Renna ◽  
Janice K. Kiecolt-Glaser

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidates are being evaluated, with the goal of conferring immunity on the highest percentage of people who receive the vaccine as possible. It is noteworthy that vaccine efficacy depends not only on the vaccine but also on characteristics of the vaccinated. Over the past 30 years, a series of studies has documented the impact of psychological factors on the immune system’s vaccine response. Robust evidence has demonstrated that stress, depression, loneliness, and poor health behaviors can impair the immune system’s response to vaccines, and this effect may be greatest in vulnerable groups such as the elderly. Psychological factors are also implicated in the prevalence and severity of vaccine-related side effects. These findings have generalized across many vaccine types and therefore may be relevant to the SARS-CoV-2 vaccine. In this review, we discuss these psychological and behavioral risk factors for poor vaccine responses, their relevance to the COVID-19 pandemic, as well as targeted psychological and behavioral interventions to boost vaccine efficacy and reduce side effects. Recent data suggest these psychological and behavioral risk factors are highly prevalent during the COVID-19 pandemic, but intervention research suggests that psychological and behavioral interventions can increase vaccine efficacy.


Author(s):  
Nam Jeong Jeong ◽  
Eunil Park ◽  
Angel P. del Pobil

Non-communicable diseases (NCDs) are one of the major health threats in the world. Thus, identifying the factors that influence NCDs is crucial to monitor and manage diseases. This study investigates the effects of social-environmental and behavioral risk factors on NCDs as well as the effects of social-environmental factors on behavioral risk factors using an integrated research model. This study used a dataset from the 2017 Korea National Health and Nutrition Examination Survey. After filtering incomplete responses, 5462 valid responses remained. Items including one’s social-environmental factors (household income, education level, and region), behavioral factors (alcohol use, tobacco use, and physical activity), and NCDs histories were used for analyses. To develop a comprehensive index of each factor that allows comparison between different concepts, the researchers assigned scores to indicators of the factors and calculated a ratio of the scores. A series of path analyses were conducted to determine the extent of relationships among NCDs and risk factors. The results showed that social-environmental factors have notable effects on stroke, myocardial infarction, angina, diabetes, and gastric, liver, colon, lung, and thyroid cancers. The results indicate that the effects of social-environmental and behavioral risk factors on NCDs vary across the different types of diseases. The effects of social-environmental factors and behavioral risk factors significantly affected NCDs. However, the effect of social-environmental factors on behavioral risk factors was not supported. Furthermore, social-environmental factors and behavioral risk factors affect NCDs in a similar way. However, the effects of behavioral risk factors were smaller than those of social-environmental factors. The current research suggests taking a comprehensive view of risk factors to further understand the antecedents of NCDs in South Korea.


Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Urvish K Patel ◽  
Priti Poojary ◽  
Vishal Jani ◽  
Mandip S Dhamoon

Background: There is limited recent population-based data of trends in acute ischemic stroke (AIS) hospitalization rates among young adults (YA). Rising prevalence of stroke risk factors may increase stroke rates in YA. We hypothesized that 1) stroke hospitalizations and mortality among YA are increasing over time (2000-2011), 2) besides traditional stroke risk factors, non-traditional factors are associated with stroke in YA, 3) stroke hospitalization among YA is associated with higher mortality, length of stay (LOS), and cost. Methods: In the Nationwide Inpatient Sample database (years 2000-2011), adult hospitalizations for AIS and concurrent diagnoses were identified by ICD-9-CM codes; the analytic cohort constituted all AIS hospitalizations. We performed weighted analysis using chi-square, t-test, and Jonckheere trend test. Multivariable survey regression models evaluated interactions between age group (18-45 vs. >45 years) and traditional and non-traditional risk factors, with outcomes including mortality, LOS, and cost. Models were adjusted for race, sex, Charlson’s Comorbidity Index, primary payer, location and teaching status of hospital, and admission day. Results: Among 5220960 AIS hospitalizations, 231858 (4.4%) were YA. On trend analysis, proportion of YA amongst AIS increased from 3.6% in 2000 to 4.7% in 2011 (p<0.0001) but mortality in YA decreased from 3.7% in 2000 to 2.6% in 2011, compared to 7.1% in 2000 to 4.6% in 2011 (p<0.0001) among older adults. Non-traditional, especially behavioral, risk factors were more common among YA, and LOS and cost were higher (Table). Conclusion: There was a trend for higher proportion of YA among AIS hospitalizations, though there was a decreasing mortality trend over 10 years. Behavioral risk factors were more common among YA, and there was an increased length of stay and cost. AIS in YA may require different preventive approaches compared to AIS among older adults.


Therapy ◽  
2021 ◽  
Vol 6_2021 ◽  
pp. 51-55
Author(s):  
Didigova R.T. Didigova ◽  
Evloeva D.A. Evloeva ◽  
Ugurchieva Z.O. Ugurchieva ◽  
Ugurchieva P.O. Ugurchieva ◽  
Malsagova I.Ya. Malsagova ◽  
...  

Author(s):  
NI Latyshevskaya ◽  
VV Mirochnik ◽  
LA Davydenko ◽  
AI Kireeva ◽  
AV Belyaeva

Summary. Introduction: Comprehensive risk management considering behavioral risk factors is a possible way to minimize adverse health effects of occupational factors. The purpose of the study was assess behavioral risk factors and to develop appropriate measures for preventing occupational diseases in oil refinery operators. Materials and methods: The observation groups included crude oil treatment operators of Ritek LLC in the Volgograd Region located in the subarid climatic zone. The first group consisted of 100 workers under the age of 35 while the second group consisted of 106 workers aged 36-60. Previously published studies were used to substantiate priority occupational risk factors for the operators. To assess lifestyle habits, we conducted a questionnaire-based survey and analyzed data in terms of their statistical significance and real controllability using a multidimensional confirmatory factor analysis. Results: We established that the priority occupational health risks of operators in the climatic conditions of the Volgograd Region included labor severity and intensity (3.1) and hot environment (3.2) posing a high occupational risk of disrupting the thermal state (overheating) of workers. We also identified typical behavioral risk factors, the prevalence and quantitative burden of which was age-specific. In the younger age group, bad habits and poor healthcare activity (reluctance to seek medical advice) generated the highest burdens (943 conditional units each) while in the older age group, major burdens were generated by bad habits and malnutrition (849 and 501 units, respectively). The developed mathematical model proved that a comprehensive health risk management for workers exposed to occupational hazards is feasible by correcting certain behavioral risk factors: a 10 % and 50 % decrease in the burden of bad habits and poor healthcare activity led to a 1.1 and 1.5-fold decrease in the extent of health risk, respectively. Conclusion: The study revealed the most significant behavioral risk factors affecting health of oil refinery operators and substantiated options of the most optimal interaction between the elements of the system reducing the overall risk to human health. Comprehensive health risk management based on optimal interaction of system elements (both occupational and behavioral risk factors) reduces health risks for oil refinery operators.


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