scholarly journals Current trends and therapies in orchialgia management

2021 ◽  
Vol 13 ◽  
pp. 175628722110264
Author(s):  
Kevin Campbell ◽  
Larry Lipshultz

The management of pain is a complex condition that will be encountered by most practicing clinicians. In the genitourinary community, testicular pain may be classified as acute or chronic. Initial evaluation of chronic groin and scrotal content pain (CGSCP) begins with a detailed history and physical examination to elucidate the presenting pathology. Multiple therapy algorithms have been proposed with no definitive consensus; however, most begin with conservative intervention and medical management prior to advancing to more invasive procedures. Surgical approaches may range from reconstruction, as in vasovasostomy for post-vasectomy pain syndrome, to excision of the offending agent, as in epididymectomy. This review seeks to focus on chronic pain in the genitourinary community and review techniques of pain management in the current intervention for orchialgia, as well as identify future methods of treatment.

Author(s):  
Navil F. Sethna ◽  
Pradeep Dinakar ◽  
Karen R. Boretsky

As part of multidisciplinary management of paediatric chronic pain, interventional pain management techniques can play an important role when pain is unrelieved by conventional treatment modalities. Many procedures and indications are extrapolated from adult studies, and evidence for long-term efficacy in paediatric populations is limited. Interventions range from injection techniques with local anaesthetic and/or corticosteroids to neuraxial blockade with implanted catheters. Paediatric case series have reported benefit in selected patients with complex regional pain syndrome and cancer-related pain.


2020 ◽  
Vol 20 (4) ◽  
pp. 707-716
Author(s):  
Calum Murray ◽  
Samantha Harrison ◽  
Andreas Goebel ◽  
Hannah Twiddy

AbstractObjectivesComplex regional pain syndrome (CRPS) is a rare chronic pain condition for which no curative treatment exists. Patients in tertiary centres are often required to make decisions about treatment options. This study was conducted to explore how prior attendance of a pain management program might alter patients’ decision making processes.MethodsThis qualitative study uses focus groups to gather patient views on an immunosuppressant drug treatment (mycophenolate) for the management of CRPS. Participants were allocated to one of three focus groups based on their treatment journey; Group 1 (n=3) were involved in a recent mycophenolate drug trial; Group 2 (n=5) were neither involved in the trial nor attended a Pain Management Programme (PMP); Group 3 (n=6) were not involved in the trial but had attended a PMP. Outcomes were considered within the framework of Leventhal’s Common Sense Model (CSM) in relation to the decision making process.ResultsThematic analysis identified differing themes for each group. Group 1: (1) Medication as a positive form of treatment, (2) The trial/drug and (3) Pacing. Group 2: (1) Medication as form of treatment, (2) Other forms of support/treatment and (3) Side effects of mycophenolate. Group 3: (1) Varied view of medication, (2) Consideration of other forms of support and (3) Side effects.ConclusionsAttendance on a PMP might provide patients with skills to better manage uncertainty when faced with various treatment options. Leventhal’s model goes some way to explaining this. The specific importance of, and benefit from understanding pacing when commencing an effective drug treatment for chronic pain became apparent.


Author(s):  
A. A. Voropaev ◽  
M. Yu. Gerasimenko ◽  
G. E. Ivanova

Background. The relevance of the work is associated with the high prevalence and socio-economic significance of chronic pain. The number of analgesics consumed in the world is estimated in the tens of tonns. Hardware effects, including neurosurgical interventions, are not always effective and are associated with many side effects of complications. Existing therapeutic and surgical approaches to the treatment of chronic pain require additions. In this regard, the information and structural theory of pain was developed, revealing the information processes occurring in the Central nervous system against the background of chronic pain, as well as the theory of psychological types and information metabolism. In this case, it is easier not to look for the right solution, but to create a mechanism that will come up with a method for finding the right solution. A neural network is one of the ways to implement artificial intelligence (AI). It studies methods for building algorithms that can learn independently. This is necessary if there is no clear solution to any problem. Aims: based on the comparison of data from neuropsychological, clinical and neurophysiological studies, as well as mathematical (neural network) modeling of chronic pain, to identify information and structural justification and practical application of psychoalgology. Methods. A total of A total of 105 patients diagnosed with Dorsopathy (M54.4; M51.1, M54.1) were studied. 50 men and 55 women, men: average age 49 0.5 years; women: average age 52 1.6 years. Assessment of the level of reactive and personal anxiety using the adapted SpielbergerHanin questionnaire, the SAN test, and the assessment of vegetative status using the vegetative questionnaire by A.M. Wein. Neuroimaging research: CT, MRI of the brain and spine for diagnostic purposes. The neurophysiological study consisted of EEG, TCD, duplex scanning of the craniocervical junction vessels. For a more detailed assessment, a neural network analyzer of lumbar pain was used, which allows predicting its course. Results. A clinical and neurophysiological study of patients with back pain revealed that, along with other disorders of cerebral neurodynamics, a large role is played by lateralization of cerebral neurodynamics (asymmetry), which is manifested by more pronounced changes in the EEG in the contralateral hemisphere. When studying the subjective state of patients, two main types of disorders were distinguished: the type of associated and the type of non-associated mental disorders. As a result of the analysis of mathematical (neural network) algorithms of pain syndromes, clinical and neurophysiological studies, new principles of chronization of the pathological process with the transformation of the pain syndrome into an independent psychological disease were formulated. ALGIC DISEASE is characterized by a pronounced clinical polymorphism due to complex information-structural interactions of dominant and subdominant zones and characterized by: 1) heterogeneity and chaotic spatial parameters of pain in relation to the zones of innervation of nociogenic structures; 2) non-topological time parameters of peripheral and Central sensitization with increased pain from instant to prolonged; 3) mutual suppression, displacement, migration of pain centers; 4) changing the monocausal dependence of the polycausal pain syndrome with the possibility of a reverse process in the process of regional integrative measures with a multidisciplinary approach; 5) the relationship of chronic pain with pronounced cognitive, emotional and vegetative reactions. Conclusions. Based on the information and structural theory of pain, the results of research and the proposed psychoalgological approach, the principles of building a rehabilitation program for patients with chronic pain are formulated, which consists in a complex effect on nociogenic structures of types 1, 2 and 3 in combination with the modification of patient behavior through individually selected psychotherapeutic techniques.


2013 ◽  
Vol 7 (5) ◽  
pp. 402-413 ◽  
Author(s):  
Susanne A. Quallich ◽  
Cynthia Arslanian-Engoren

Past investigations of chronic testicular pain provide a sparse representation of the men with this condition and lack key details to aid our understanding of this important men’s health condition. As a chronic pain syndrome, more research is necessary to understand the phenomenon of chronic testicular pain and the pain experience of these men. This integrative literature review provides a summary of the current state of the science of chronic testicular pain in men, identifies the gaps in our knowledge, and provides recommendations to address this knowledge gap.


2021 ◽  
Vol 5 ◽  
pp. 5-13
Author(s):  
A.M. Morozov ◽  
◽  
A.N. Sergeev ◽  
V.A. Kadykov ◽  
S.V. Zhukov ◽  
...  

At the present time, approximately 80% patients experience postoperative pain which is the leading entity in the overall structure of chronic pain. The aim of this article is investigation of reasons and risk factors underlying its development. Based on the information provided in domestic and international sources in open databases, analysis of these problems has been carried out. Selection of adequate therapy is particularly important against the background of the need for long-term intake of strong analgesics or the impossibility of pain management due to the neurogenic aetiology of the disease. In this connection, it is necessary to study factors predisposing patients to development of chronic postoperative pain and resort to prevention measures in order to reduce the risk of pain syndrome development.


2018 ◽  
Vol 1 (21;1) ◽  
pp. E207-E214 ◽  
Author(s):  
Dr. Stephen Thorp

Background: Chronic pain is a major public health problem resulting in physical and emotional pain for individuals and families, loss of productivity, and an annual cost of billions of dollars. The lack of objective measures available to aid in diagnosis and evaluation of therapies for chronic pain continues to be a challenge for the clinician. Objectives: Functional magnetic resonance imaging (fMRI) is an imaging technique that can establish regional areas of interest and examine synchronous neuronal activity in functionally related but anatomically distinct regions of the brain, known as functional connectivity. Study Design: The present investigation examines changes in functional connectivity in 4 common pain syndromes: chronic back pain (CBP), fibromyalgia, diabetic neuropathy, and complex regional pain syndrome (CRPS). Setting: This is a review of the current understanding of functional connectivity. Methods: Utilizing functional imaging, patients with these conditions have been shown to have significant structural and functional differences when compared to healthy controls. Results: Functional connectivity, therefore, has the potential to assist in diagnostic classification of different pain conditions, predict individual responses to specific therapeutic interventions, and serve as a gateway for personalized medicine. Indirect activation of brain activity can be seen by the blood flow to the brain at specific sites, with chronic pain patients having increased brain activity. Limitations: The present investigation is limited in that few studies have examined this relatively new modality. Conclusions: Knowing and observing the brain’s activity as related to pain gives pain patients an opportunity to decrease pain-related brain activity and decrease severe chronic pain. This modality can be used along with interventional pain management techniques in order to provide optimum pain relief. Key words: Functional connectivity, fMRI, chronic pain, chronic back pain, fibromyalgia, diabetic neuropathy, chronic regional pain syndrome


Author(s):  
V. I. Moroz ◽  
M.. B. Balaeva ◽  
A. V Naumov ◽  
N. O. Khovasova

This article describes a clinical case of a patient with chronic pain syndrome on the background of osteoarthritis, with a history of joint replacement. The reason for hospitalization was a fall, after which a constant pain syndrome persisted and a neuropathic component joined, which the patient could not stop with anything.As a result of a comprehensive geriatric assessment, the patient was diagnosed with frailty and the following geriatric syndromes: mild dependence on outside help, chronic pain syndrome, balance disorders, falls, stress urinary incontinence. Non-drug methods of treatment and complex therapy (gabapentin + B vitamins + uridine) and antiosteoporetic therapy were recommended, against which the intensity of the pain syndrome decreased to a mild degree (according to the VAS scale of 2 points at the time of discharge) and a decrease in neuropathy copatterns was noted.


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