Decorosides A and B, Cytotoxic Flavonoid Glycosides from the Leaves of Rhododendron decorum
2014 ◽
Vol 9
(4)
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pp. 1934578X1400900
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Keyword(s):
Bioassay and NMR-guided fractionation of the methanolic extract of Rhododendron decorum leaves resulted in the isolation of two new flavonoid glycosides, 5,7-dihydroxy-6,8-dimethyldihydroflavanone-7-O-α-L-arabinopyranosyl(l→6)-β-D-glucopyranoside (decoroside A, 1) and its 3-hydroxy congener (decoroside B, 2), along with five known compounds myricitrin (3), afzelin (4), (-)-epicatechin (5), (+)-catechin (6), and ampeloptin (7). The structures of the isolated compounds were elucidated by extensive interpretation of their spectral data. Biological evaluation using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay revealed promising cytotoxic activities of these compounds against different cancer cell lines.
2018 ◽
Vol 8
(3)
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pp. 159
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Keyword(s):
2020 ◽
Vol 17
(11)
◽
pp. 1330-1341
Keyword(s):
2016 ◽
Vol 17
(1)
◽
pp. 137-142
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Keyword(s):