scholarly journals Biotechnological Valorization of Pectinolytics and Their Industrial Applications: A Review

2014 ◽  
Vol 9 (11) ◽  
pp. 1934578X1400901 ◽  
Author(s):  
Muhammad Irshad ◽  
Muhammad Asgher ◽  
Zahid Anwar ◽  
Aftab Ahmad
Keyword(s):  
Large Scale ◽  
Value Added ◽  
Cost Effective ◽  
Industrial Applications ◽  
Green Biotechnology ◽  
A Value ◽  
Physico Chemical ◽  
Target Yield ◽  
High Yields ◽  
Agricultural Materials

In the last several years, in serious consideration of the worldwide economic and environmental issues there has been an increasing research interest in the value of naturally occurring bio-sourced materials. Agro-industrial based biomass comprised of pectin is an inexpensive, renewable, abundant natural resource that could be utilized for large-scale and cost-effective production of natural products i.e., pectinolytics. Pectinolytics are one of the most widely distributed enzymes in bacteria, fungi and plants. From ancient times to date, many methods have been introduced to improve the optimization of pectinolytics to obtain high yields of maximal purity. To expand the range of natural bio-resources the rapidly evolving tools of biotechnology can lower the conversion costs and also enhance target yield of the product of interest. This green biotechnology presents a promising approach to convert most of the agricultural materials into a value-added product with multiple applications. Major advances have already been achieved in recent years in order to obtain high levels of purity with optimal yields. The present review begins with an overview of pectinolytics and their physico-chemical features, and their specific role with classification based on pectic materials. Information is also given on the culture influences and potential sources of pectinolytics, followed by a brief summary of various industrial and biotechnological applications and future considerations.

scholarly journals Multi-Country Scale Assessment of Available Energy Recovery Potential Using Micro-Hydropower in Drinking, Pressurised Irrigation and Wastewater Networks, Covering Part of the EU

Water ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 899
Author(s):  
Djordje Mitrovic ◽  
Miguel Crespo Chacón ◽  
Aida Mérida García ◽  
Jorge García Morillo ◽  
Juan Antonio Rodríguez Diaz ◽  
...  
Keyword(s):  
Drinking Water ◽  
Northern Ireland ◽  
Energy Recovery ◽  
Large Scale ◽  
Significant Proportion ◽  
Value Added ◽  
Cost Effective ◽  
Net Energy ◽  
Water Networks ◽  
Scale Assessment

Studies have shown micro-hydropower (MHP) opportunities for energy recovery and CO2 reductions in the water sector. This paper conducts a large-scale assessment of this potential using a dataset amassed across six EU countries (Ireland, Northern Ireland, Scotland, Wales, Spain, and Portugal) for the drinking water, irrigation, and wastewater sectors. Extrapolating the collected data, the total annual MHP potential was estimated between 482.3 and 821.6 GWh, depending on the assumptions, divided among Ireland (15.5–32.2 GWh), Scotland (17.8–139.7 GWh), Northern Ireland (5.9–8.2 GWh), Wales (10.2–8.1 GWh), Spain (375.3–539.9 GWh), and Portugal (57.6–93.5 GWh) and distributed across the drinking water (43–67%), irrigation (51–30%), and wastewater (6–3%) sectors. The findings demonstrated reductions in energy consumption in water networks between 1.7 and 13.0%. Forty-five percent of the energy estimated from the analysed sites was associated with just 3% of their number, having a power output capacity >15 kW. This demonstrated that a significant proportion of energy could be exploited at a small number of sites, with a valuable contribution to net energy efficiency gains and CO2 emission reductions. This also demonstrates cost-effective, value-added, multi-country benefits to policy makers, establishing the case to incentivise MHP in water networks to help achieve the desired CO2 emissions reductions targets.

Aligning the flow cytometric evaluation with the diagnostic need: an evidence-based approach

2017 ◽  
Vol 70 (9) ◽  
pp. 740-744 ◽  
Author(s):  
Dawn Williams-Voorbeijtel ◽  
Francisco Sanchez ◽  
Christine G Roth
Keyword(s):  
Clinical Care ◽  
Cost Savings ◽  
Value Added ◽  
Cost Effective ◽  
Just In Time ◽  
Evidence Based ◽  
Flow Cytometric ◽  
A Value ◽  
Screening Approach ◽  
Minimum Requirements

AimsElimination of non-value added testing without compromising high-quality clinical care is an important mandate for laboratories in a value-based reimbursement system. The goal of this study was to determine the optimal combination of flow cytometric markers for a screening approach that balances efficiency and accuracy.MethodsAn audit over 9 months of flow cytometric testing was performed, including rereview of all dot plots from positive cases.ResultsOf the 807 cases in which leukaemia/lymphoma testing was performed, 23 were non-diagnostic and 189 represented bronchoalveolar lavage specimens. Of the remaining 595 cases, 137 (23%) were positive for an abnormal haematolymphoid population. Review of the positive cases identified minimum requirements for a screening tube as well as analysis strategies to overcome the diagnostic pitfalls noted. It is estimated that 38% fewer antibodies would be used in a screening approach, representing an opportunity for significant cost savings.ConclusionsWe provide a framework for developing an evidence-based screening combination for cost-effective characterisation of haematolymphoid malignancies, promoting adoption of ‘just-in-time’ testing systems that tailor the evaluation to the diagnostic need.

scholarly journals Sugarcane Wax - A Par Excellent by-Product of Sugar Industry - A Review

2020 ◽  
Author(s):  
S. Mohan ◽  
L. Chithra ◽  
R. Nageswari ◽  
V. Manimozhi Selvi ◽  
M. Mathialagan
Keyword(s):  
Sugar Industry ◽  
Economic Value ◽  
Value Added ◽  
Industrial Applications ◽  
Press Mud ◽  
A Value ◽  
Cash Crops ◽  
By Products ◽  
Sugarcane Processing ◽  
Value Added Products

Sugarcane is one of the major cash crops, used for the production of sugar and ethanol. Sugarcane processing, results in many by by-products like bagasse, molasses and press mud which have economic value. Also, the by-products serve to generate many value added products. Sugarcane wax is a value added product obtained by the processing of press mud. It has pharmaceutical, agricultural and industrial applications. n-Triacontanol, Policosanol, D-003 acids and waxes are some of the products derived from the sugarcane wax. This article attempt discusses the various methods of extraction of sugarcane wax, its constituents and its characteristics and applications of the products derived from the sugarcane wax.

A Short Review on Recent Development of Laccase Immobilization on Different Support Materials

2021 ◽  
Vol 02 (01) ◽  
Author(s):  
Norsyafiqah Amalina Ahmad Jafri ◽  
◽  
Roshanida A. Rahman ◽  
Noorhalieza Ali ◽  
◽  
...  
Keyword(s):  
Large Scale ◽  
Cost Effective ◽  
Short Review ◽  
Industrial Applications ◽  
Innovative Strategies ◽  
Support Materials ◽  
High Production ◽  
Efficient Recovery ◽  
High Production Cost ◽  
Laccase Immobilization

Laccase is a bio catalytic agent and multi-copper enzyme containing oxidases that are potentially great for oxidizing large number of phenolic and non-phenolic compounds. However, drawbacks do arise when laccase use in large scale; low in stability, high production cost, non-reusability, sensitive towards denaturing and poor storage ability of free enzymes. These problems lead to the progress in laccase immobilization in order to facilitate the efficient recovery and re-use of the enzyme, thus enabling cost-effective in continuous processes. Apart from discussing on different methods in laccase immobilization such as entrapment, encapsulation and cross-linking in general, we have reviewed a recent development in laccase immobilization on different supports or carriers binding (natural and synthetic). Future works are recommended to focus on innovative strategies on the modified supports to improve the enzyme immobilization as well as sensible entrapment techniques for industrial applications.

A Reanalysis of the Effects of Teacher Replacement Using Value-Added Modeling

2013 ◽  
Vol 115 (12) ◽  
pp. 1-35
Author(s):  
Stuart S. Yeh
Keyword(s):  
Student Achievement ◽  
Large Scale ◽  
Reliability And Validity ◽  
Value Added ◽  
Cost Effective ◽  
Large Numbers ◽  
Cost Effective Approach ◽  
Need To Evaluate ◽  
Value Added Modeling ◽  
Lifetime Earnings

Background In principle, value-added modeling (VAM) might be justified if it can be shown to be a more reliable indicator of teacher quality than existing indicators for existing low-stakes decisions that are already being made, such as the award of small merit bonuses. However, a growing number of researchers now advocate the use of VAM to identify and replace large numbers of low-performing teachers. There is a need to evaluate these proposals because the active termination of large numbers of teachers based on VAM requires a much higher standard of reliability and validity. Furthermore, these proposals must be evaluated to determine if they are cost-effective compared to alternative proposals for raising student achievement. While VAM might be justified as a replacement for existing indicators (for existing decisions regarding merit compensation), it might not meet the higher standard of reliability and validity required for large-scale teacher termination, and it may not be the most cost-effective approach for raising student achievement. If society devotes its resources to approaches that are not cost-effective, the increase in achievement per dollar of resources expended will remain low, inhibiting reduction of the achievement gap. Objective This article reviews literature regarding the reliability and validity of VAM, then focuses on an evaluation of a proposal by Chetty, Friedman, and Rockoff to use VAM to identify and replace the lowest-performing 5% of teachers with average teachers. Chetty et al. estimate that implementation of this proposal would increase the achievement and lifetime earnings of students. The results appear likely to accelerate the adoption of VAM by school districts nationwide. The objective of the current article is to evaluate the Chetty et al. proposal and the strategy of raising student achievement by using VAM to identify and replace low-performing teachers. Method This article analyzes the assumptions of the Chetty et al. study and the assumptions of similar VAM-based proposals to raise student achievement. This analysis establishes a basis for evaluating the Chetty et al. proposal and, in general, a basis for evaluating all VAM-based policies to raise achievement. Conclusion VAM is not reliable or valid, and VAM-based polices are not cost-effective for the purpose of raising student achievement and increasing earnings by terminating large numbers of low-performing teachers.

An Efficient Straightforward Synthesis of Antidepressant Drug Moclobemide

2020 ◽  
Vol 5 (2) ◽  
pp. 174-1778
Author(s):  
Santoshkumar M. Potdar ◽  
Krishnakant T. Waghmode
Keyword(s):  
Present Method ◽  
Large Scale ◽  
Antidepressant Drug ◽  
Cost Effective ◽  
Reaction Conditions ◽  
Chlorobenzoic Acid ◽  
Free Condition ◽  
Solid Catalysts ◽  
Synthetic Strategy ◽  
High Yields

Efferent, new and simple synthesis for antidepressant drug moclobemide has been developed via two liner steps. Initially, morpholine treated with 60% aqueous solution of 2-bromoethylamine hydrochloride under solvent and catalyst free condition leads to a key intermediate N-(2-aminoethyl)morpholine, which subsequently treated with p-chlorobenzoic acid in presence of commercially available solid catalysts, afforded moclobemide with good yield. Mild reaction conditions, short reaction time, easy workup, cost-effective, environment friendliness and high yields are attractive advantages of the present method, so our synthetic strategy was applicable to large scale manufacturing of moclobemide every conveniently.

scholarly journals Filament profiles from WISExSCOS galaxies as probes of the impact of environmental effects

2020 ◽  
Vol 638 ◽  
pp. A75 ◽  
Author(s):  
V. Bonjean ◽  
N. Aghanim ◽  
M. Douspis ◽  
N. Malavasi ◽  
H. Tanimura
Keyword(s):  
Galaxy Evolution ◽  
Large Scale ◽  
Value Added ◽  
Gas Content ◽  
Large Scale Structures ◽  
A Value ◽  
The Galaxy ◽  
Scale Structures ◽  
Isothermal Gas ◽  
The Impact

The role played by large-scale structures in galaxy evolution is not very well understood yet. In this study, we investigated properties of galaxies in the range 0.1 <  z <  0.3 from a value-added version of the WISExSCOS catalogue around cosmic filaments detected with DisPerSE. We fitted a profile of galaxy over-density around cosmic filaments and found a typical radius of rm = 7.5 ± 0.2 Mpc. We measured an excess of passive galaxies near to the spine of the filament that was higher than the excess of transitioning and active galaxies. We also detected star formation rates (SFR) and stellar mass (M⋆) gradients pointing towards the spine of the filament. We investigated this result and found an M⋆ gradient for each type of galaxy, that is active, transitioning, and passive; we found a positive SFR gradient for passive galaxies. We also linked the galaxy properties and gas content in the cosmic web. To do so, we investigated the quiescent fraction fQ profile of galaxies around the cosmic filaments. Based on recent studies about the effect of the gas and the cosmic web on galaxy properties, we modelled fQ with a β model of gas pressure. The slope obtained in this work, β = 0.54 ± 0.18, is compatible with the scenario of projected isothermal gas in hydrostatic equilibrium (β = 2/3) and with the profiles of gas fitted in Sunyaev-Zel’dovich data from the Planck satellite.

scholarly journals Strategies to Produce Cost-Effective Third-Generation Biofuel From Microalgae

2021 ◽  
Vol 9 ◽  
Author(s):  
Nazifa Rafa ◽  
Shams Forruque Ahmed ◽  
Irfan Anjum Badruddin ◽  
M. Mofijur ◽  
Sarfaraz Kamangar
Keyword(s):  
Large Scale ◽  
Cost Minimization ◽  
Value Added ◽  
Cost Effective ◽  
Global Market ◽  
Production Costs ◽  
Biodiesel Production ◽  
Third Generation ◽  
The Cost ◽  
Generation Biofuel

Third-generation biofuel produced from microalgae is a viable solution to global energy insecurity and climate change. Despite an annual current global algal biomass production of 38 million litres, commercialization confronts significant economic challenges. However, cost minimization strategies, particularly for microalgae cultivation, have largely been excluded from recent studies. Therefore, this review provides essential insights into the technologies and economics of cost minimization strategies for large-scale applications. Cultivation of microalgae through aquafarming, in wastewater, or for biogas upgrading, and co-production of value-added products (VAPs) such as photo-bioreactors, protein, astaxanthin, and exopolysaccharides can drastically reduce biodiesel production costs. For instance, the co-production of photo-bioreactors and astaxanthin can reduce the cost of biodiesel production from $3.90 to $0.54 per litre. Though many technical challenges need to be addressed, the economic analysis reveals that incorporating such cost-effective strategies can make the biorefinery concept feasible and profitable. The cost of producing microalgal biodiesel can be lowered to $0.73kg−1 dry weight when cultivated in wastewater or $0.54L−1 when co-produced with VAPs. Most importantly, access to co-product markets with higher VAPs needs to be encouraged as the global market for microalgae-based VAPs is estimated to rise to $53.43 billion in 2026. Therefore, policies that incentivize research and development, as well as the production and consumption of microalgae-based biodiesel, are important to reduce the large gap in production cost that persists between biodiesel and petroleum diesel.

Cognitive Services in Nutrition Support Pharmacy

1994 ◽  
Vol 7 (6) ◽  
pp. 271-279
Author(s):  
James J. Murray
Keyword(s):  
Value Added ◽  
Cost Effective ◽  
Outpatient Setting ◽  
Third Party ◽  
Nutrition Support ◽  
Therapy Outcomes ◽  
Cognitive Services ◽  
A Value ◽  
Home Infusion ◽  
Opportune Time

Many new opportunities are available to the clinical pharmacist in search of an appropriate environment in which to tailor specific clinical services. This is an opportune time for pharmacists to become more creative in their practice settings and to become more involved with, and responsible for, the therapy process of patients. Cognitive services provide a value-added service to the patient, physician, and third-party payor. The value of pharmaceutical cognitive services becomes more evident in the outpatient setting. The value of cognitive services varies depending on the practice setting, demographics of the patient, and resources of the pharmacy organization. This article describes a pharmacist's experience in developing nutritional support cognitive services to patients and targeted physicians in an outpatient home infusion pharmacy. If properly developed, a well-marketed cognitive service can add tremendous revenue to a pharmacy by creating respect and loyalty from physicians and third-party payors, creating a formidable patient base. Cognitive services are not reimbursed separately at present, but future studies should show the value of these services if more pharmacists will provide cost-effective cognitive services and be able to show more positive patient therapy outcomes.

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