A Novel C21 Cyclopentenone Derivative from Cipadessa Cinerascens
2015 ◽
Vol 10
(8)
◽
pp. 1934578X1501000
A new C21 cyclopentenone derivative, Cipacyclonone (1), was isolated from the leaves of Cipadessa cinerascens. Its structure was elucidated on the basis of spectroscopic analysis, including extensive 1D- and 2D-NMR techniques. Compound 1 showed strong cytotoxicity activity against HL-60 and A-549 cell lines, with IC50 values of 1.2 and 3.0 μM, respectively.