scholarly journals Environmental Arsenic Contamination and its Effect on Dental Caries Experience in School Children

2017 ◽  
Vol 8 (1-2) ◽  
pp. 21-25
Author(s):  
Manju R. ◽  
Amitha M. Hegde ◽  
Anisha Keshan
Keyword(s):  
Arsenic Exposure ◽  
Caries Experience ◽  
Control Group ◽  
Study Group ◽  
Hair Samples ◽  
Icdas Ii ◽  
Chronic Arsenic Exposure ◽  
The Mean ◽  
And Control ◽  
Possible Cause

Aims and Objectives: To assess the effect of exposure to arsenic by drinking water and caries prevalence in children. Material and Methods: A total of 200 children between 10 to 14 years of age, 100 each from study village (Hutti, Raichur district, Karnataka) and control village (Sanduru, Bellary district, North Karnataka) were included in the study. Water samples from both the villages were analyzed for arsenic levels. Arsenic levels were determined in the hair and nail samples from the subjects to assess chronic arsenic exposure. Caries experience was measured by the DMFT/deft index and the severity of caries was measured by modified ICDAS-II index. Results: The mean concentration of arsenic in the study group was found to be 2.44 ppm in the hair samples and 2.72 ppm in the nail samples as compared to 0.12 ppm in both hair and nail samples in the control group. These values were statistically significant ( p < 0.001). The mean DMFT score in the control group was 0.99 and in the study group was 2.45, which was statistically significant ( p < 0.05) using SPSS version 21. Conclusion: Chronic arsenic exposure could be a possible cause for the increased caries experience in children in the study group.

scholarly journals True and Pseudo Cholinesterase levels in short and long-term of pesticides exposures

2020 ◽  
pp. 9-12
Author(s):  
Mohammed Abdul Rahman ◽  
Raghunatha Rao D ◽  
Vasantha L
Keyword(s):  
Whole Blood ◽  
Acute Poisoning ◽  
Mean Value ◽  
Serum Cholinesterase ◽  
Control Group ◽  
Study Group ◽  
Chronic Poisoning ◽  
The Mean ◽  
The Difference ◽  
And Control

The present study is aimed to study and analyze the true and pseudo Cholinesterase levels in the subjects exposed to pesticides during short term by intentional or accidental intake and long term exposure due to their occupation were studied at Department of Biochemistry, SVS medical college and hospital mahbubnagar district. Whole blood cholinesterase levels and Pseudo cholinesterase levels were estimated. 150 people were taken as controls who had no medical illness and a total number of 300 cases of pesticide poisoning were selected, aged between 20 to 55 years, which consist of 150 acute poisoning and 150 chronic poisoning subjects in Mahbubnagar district, were taken as case study, the detailed case history and the type of organophosphorus pesticide taken were recorded. Mean and standard deviation (S.D) of all variables were calculated and compared with those of controls. Statistical significance was assessed and P-value <0.05 were considered significant.           During acute poisoning the mean value of Whole blood cholinesterase/True cholinesterase (U / L) in acute poisoning cases on first day was 1.267± 0.612 on 3th day was 1.651±0.647, on 7th day was 2.221±0.684 and at the end of 6 months was 3.970±0.404.The difference between the study group and control group (4.0 ± 0.39) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in acute poisoning cases on first day was 2213.05 ± 1749.81, on 3th day was 2862.3 ± 2025.6, on 7th day was 4008.4 ± 2355.9 and at the end of 6 months was 7708.34 ± 880.72.The difference between the study group and control group (7991.97 ± 1276.5) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. During chronic poisoning (exposure) the mean value of Whole blood cholinesterase (U/L) in controls is 4.0 ± 0.39 as compared to 3.019 ± 0.848 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in controls was 7991.97 ± 1276.5 as compared to 6214 ± 1189 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant.

Evaluation of Salivary Sialic Acid Levels in Acute Lymphoblastic Leukemic Children and Its Correlation with Dental Caries Experience

2013 ◽  
Vol 37 (3) ◽  
pp. 309-313 ◽  
Author(s):  
S Joshi ◽  
AM Hegde ◽  
K Rai ◽  
S Shetty
Keyword(s):  
Sialic Acid ◽  
Dental Caries ◽  
Linear Relationship ◽  
Caries Experience ◽  
Control Group ◽  
Study Group ◽  
Saliva Collection ◽  
The Mean

Aim- The aim of present study was to evaluate the salivary sialic acid levels in Acute Lymphoblastic Leukemic (ALL) children and to correlate it with dental caries experience. Method- A total of 120 children aged 4-10yrs were divided into 4 groups of 30 each. Dental caries experience was recorded followed by un-stimulated saliva collection. Results- The mean salivary sialic acid levels of the study group were much higher when compared with the control group, which was statistically significant. A linear relationship between salivary sialic acid levels and dental caries in leukemic children was observed. Conclusion - The findings of our study conclude that salivary sialic acid levels may have a potent activity in dental caries process and can be used as a useful marker in cancer.

Increased Mean Platelet Volume in Patients With Aortic Stenosis

2010 ◽  
Vol 17 (6) ◽  
pp. E17-E20 ◽  
Author(s):  
Ercan Varol ◽  
Akif Arslan ◽  
Habil Yucel ◽  
Mehmet Ozaydin ◽  
Dogan Erdogan ◽  
...  
Keyword(s):  
Aortic Stenosis ◽  
Platelet Activation ◽  
Mean Platelet Volume ◽  
Matched Control ◽  
Control Group ◽  
Study Group ◽  
Platelet Volume ◽  
Echocardiographic Examination ◽  
The Mean ◽  
And Control

Background: Systemic thromboembolism is a serious complication in patients with aortic stenosis (AS). Previous studies have demonstrated that platelet activation occurs in patients with AS. The aim of this study was to assess the mean platelet volume (MPV), an indicator of platelet activation in patients with AS. Patients and Methods: The study group consisted of 43 patients with AS. An age-, gender-, and body mass index−matched control group consisted of 35 healthy volunteers. All patients and control participants underwent echocardiographic examination. We measured the serum MPV values in patients and control participants. Results: Mean platelet volume was significantly higher among patients with AS when compared with the control group (8.7 ± 1.0 vs 7.9 ± 0.9 fL, respectively; P = .001). Conclusion: We have shown that MPV was significantly elevated in patients with AS compared to control participant.

Cytomorphometric and Morphological Analysis in Women with Trichomonas vaginalis Infection: Micronucleus Frequency in Exfoliated Cervical Epithelial Cells

2015 ◽  
Vol 59 (3) ◽  
pp. 258-264 ◽  
Author(s):  
Zehra Safi Oz ◽  
Banu Doğan Gun ◽  
Mustafa Ozkan Gun ◽  
Sukru Oguz Ozdamar
Keyword(s):  
Epithelial Cells ◽  
Trichomonas Vaginalis ◽  
Control Group ◽  
Study Group ◽  
Control Groups ◽  
The Mean ◽  
The Difference ◽  
Group 2 ◽  
And Control ◽  
Group 1

Objectives: The aim of this study was to explore the cytomorphometric and morphological effects of Trichomonas vaginalis in exfoliated epithelial cells. Study Design: Ninety-six Pap-stained cervical smears were divided into a study group and two control groups as follows: T. vaginalis cases, a first control group with inflammation, and a second control group without inflammation. Micronucleated, binucleated, karyorrhectic, karyolytic, and karyopyknotic cells and cells with perinuclear halos per 1,000 epithelial cells were counted. Nuclear and cellular areas were evaluated in 70 clearly defined cells in each smear using image analysis. Results: The frequencies of morphological parameters in the T. vaginalis cases were higher than the values of the two control groups, and the difference among groups was found to be significant (p < 0.05). The nuclear and cytoplasmic areas of epithelial cells were diminished in patients with trichomoniasis. The mean nucleus/cytoplasm ratio in T. vaginalis patients was higher than the value in the control groups, and the difference between the study group and control group 1 was significant. However, there was no statistically significant increase between the study group and control group 2. Conclusions:T. vaginalis exhibited significant changes in the cellular size and nuclear structure of the cells. The rising frequency of micronuclei, nuclear abnormalities, and changing nucleus/cytoplasm ratio may reflect genotoxic damage in trichomoniasis.

TNF-α and intPLA2 genes' polymorphism in anorexia nervosa

2004 ◽  
Vol 16 (6) ◽  
pp. 290-294 ◽  
Author(s):  
Agnieszka Slopien ◽  
Filip Rybakowski ◽  
Monika Dmitrzak-Weglarz ◽  
Piotr Czerski ◽  
Joanna Hauser ◽  
...  
Keyword(s):  
Anorexia Nervosa ◽  
Gene Polymorphism ◽  
Control Group ◽  
Study Group ◽  
Intron 1 ◽  
Tnf Α ◽  
The Mean ◽  
Polymerase Chain ◽  
And Control ◽  
Necrosis Factor

Objective:The aim of this study was the assessment of −308G/A tumor necrosis factor (TNF)-α gene polymorphism and intPLA2 gene polymorphism in patients with anorexia nervosa (AN) and healthy controls.Subjects:We studied 91 non-related patients with AN and 144 healthy women (blood donors and students). The mean age of women from study group was 18.22 years (SD ± 3.13 years) and from control group was 31.71 years (SD ± 8.22).Methods:Gene polymorphisms were studied with the use of polymerase chain reaction-restriction fragment length polymorphism method. TNF-α gene polymorphism consists of G/A substitution in −308 promoter region. IntPLA2 gene polymorphism is related to intron 1, in which restrictive region is found and recognized by BanI enzyme.Results:We did not obtain statistically significant differences in the frequency of genotypes and alleles of −308G/A TNF-α polymorphism between the study and control groups (genotypes: P = 0.106, alleles: P = 0.076). We did analogous analysis in the restrictive and bulimic subgroups. We did not observe statistically relevant differences in the frequency of genotypes (P = 0.700) and alleles (P = 0.305). We did not obtain statistically relevant difference in the frequency of genotypes and alleles of intPLA2 gene between the study group and controls (genotypes: P = 0.300, alleles: P = 0.331). We did analogous analysis in both subgroups of AN. We did not observe statistically relevant differences in the frequency of genotypes (P = 0.344) and alleles (P = 0.230).Conclusions:There was no statistically relevant trend for the association between TNF-α polymorphism and AN. We did not find association between studied polymorphism of intPLA2 gene and risk of AN.

scholarly journals Effect of Foetal Movement Counting on Prenatal Attachment and Maternal Worries among Primigravidas- A Longitudinal Study

2021 ◽  
Author(s):  
Jignya Vinodbhai Asari ◽  
Anjali Pushkar Tiwari
Keyword(s):  
Longitudinal Study ◽  
Control Group ◽  
P Value ◽  
Study Group ◽  
Prenatal Attachment ◽  
Study Results ◽  
Significant Difference ◽  
The Mean ◽  
Foetal Movement ◽  
And Control

Introduction: Pregnant woman experience various physical, emotional, and hormonal changes that may cause anxiety. The anxiety and worries can be decreased by sharing information about the developing child, like foetal body movement. Aim: To assess effect of Foetal Movement Counting (FMC) on prenatal attachment and maternal worries among primigravida mothers. Materials and Methods: A longitudinal study was carried out among primigravida mothers of selected Hospitals of Central Gujarat using proforma of Cranley’s maternal foetal attachment scale and Cambridge worry scale. The study was conducted from March 2019 to July 2020. Eighty participants were recruited by convenient sampling 40 in each study group and control group. The study group were provided with foetal movement chart and the participants were asked to record foetal movements for seven consecutive days, twice a day for 20 minutes. Post assessment of prenatal attachment and maternal worries was done using tools of data collection for both study and control group. Chi- square test was used to test the significance (p-value <0.05). Results: The study results revealed that in study group mean score for prenatal attachment was 79.43 at the start and improved to 101.25 (p-value <0.001) after seven days of FMC. In control group, the mean score for prenatal attachment did not show significant difference pre-test and post-test (74.20 vs 74.85, p-value=0.077). In study group, the mean Cambridge worry scale score was 36.55 which came down to 20.28 (p-value <0.001) after seven days, while in control group it was 41.38 at the beginning and 41.30 after seven days (p-value=0.998). Conclusion: Foetal Movement Counting was found to improve maternal foetal attachment and reduce maternal worries. FMC can be routinely and effectively promoted among the pregnant population to help them achieve a positive pregnancy experience and outcome.

scholarly journals The Relationship Between Intraabdominal Hypertension and Preeclampsia

2016 ◽  
pp. 5
Author(s):  
Mesut A. Ünsal ◽  
Ülkü İnce ◽  
Sevil Cengiz ◽  
S. Caner Karahan ◽  
Turhan Aran
Keyword(s):  
Statistical Significance ◽  
Intraabdominal Pressure ◽  
Control Group ◽  
Abdominal Pressure ◽  
Study Group ◽  
Abdominal Hypertension ◽  
Intraabdominal Hypertension ◽  
The Mean ◽  
And Control ◽  
The Relationship

<p><strong>OBJECTIVE:</strong> We aimed to measure abdominal pressure and placental levels of malondialdehyde in patients with preeclampsia and investigate the relationship between intraabdominal pressure and clinical features of preeclampsia.<br /><strong>STUDY DESIGN:</strong> Study was conducted at a tertiary referral clinic. Study group consisted of patients with preeclampsia and control group consisted of normotensive pregnant women. Both placental malondialdehyde and intraabdominal pressure levels were studied in all patients. Intraabdominal pressure was assessed indirectly via a Foley bladder catheter both antepartum and postpartum period. Statistical comparisons among groups were made using the Mann-Whitney U test, independent T test and Chi-square test. Statistical significance was set as p&lt;0.05.<br /><strong>RESULTS:</strong> Study and control group consisted of 35 pregnant patients. The mean patients’ age, gravidity, parity, weight and BMI were not different between study and control groups. In the study group, Caesarean, preterm delivery and abdominal hypertension rate were significantly higher whereas the mean neonatal birth weight was lower. The mean antepartum and postpartum intraabdominal pressure levels were significantly higher in study group. The mean intraabdominal pressure was highest in patients with oliguria (19.8±1.8 cmH2O). Abdominal hypertension was detected in 30 (86%) patients in study group and in 3 (9%) patients in control group. The mean placental malondialdehyde level was significantly higher in patients with intraabdominal hypertension.<br /><strong>CONCLUSION:</strong> Abdominal hypertension rate is very high in patients with preeclampsia. Abdominal hypertension may have an additional role in preeclampsia.</p>

scholarly journals The effect and safety of placental blood drainage as a part of active management of third stage of labour in spontaneous vaginal delivery

2019 ◽  
Vol 8 (5) ◽  
pp. 1977
Author(s):  
Nidhi Gupta ◽  
Mohita Agarwal ◽  
Saroj Singh ◽  
Parul Gangwar
Keyword(s):  
Blood Loss ◽  
Uttar Pradesh ◽  
Active Management ◽  
Control Group ◽  
Study Group ◽  
Medical College ◽  
Third Stage ◽  
Placental Blood ◽  
The Mean ◽  
And Control

Background: In placental cord drainage facilitates placental delivery in both vaginal and caesarean section deliveries. The present study was done to evaluate the effect and safety of placental blood drainage as a part of active management of third stage of labour to reduce the duration and blood loss during third stage of labour.Methods: The study was conducted in department of Obstetrics and, SN Medical College, Agra, Uttar Pradesh, India on 400 term pregnant women, with single live intrauterine fetus in cephalic presentation, without any complication. They were randomly divided into to study and control group. Study group: It comprised of 200 Gynaecology cases, underwent active management of third stage of labour with placental blood drainage. Control group: It comprised of 200 cases, underwent active management of third stage of labour (AMTSL) alone. Duration and blood loss during third stage were noted.Results: The mean duration of third stage of labour was 3.61±0.972mins in study group and 8.15±1.711mins in control group. The mean blood loss during third stage of labour was 168.14±76.703ml and 287.40±85.808ml in study and control group respectively.Conclusions: Duration of third stage, blood loss during third stage, and hemoglobin deference between pre and post-delivery were reduced significantly in study group than control group.

Oral Health Status in Autism Patients Children in Iraq

2021 ◽  
Vol 19 (6) ◽  
pp. 54-60
Author(s):  
Raghad R. Al-Zaidi
Keyword(s):  
Oral Health ◽  
Dental Caries ◽  
Oral Care ◽  
Mean Value ◽  
Permanent Teeth ◽  
Caries Experience ◽  
Control Group ◽  
Study Group ◽  
Significant Difference ◽  
And Control

Background: The autism spectrum disorder (ASD) has been introduced as one of the complicated developmental disabilities impairing communication and behavioral, intellectual as well as social functioning describes diverse symptoms, such as difficulties in communication skills and social interactions. The present research has been performed to assess seriousness of the dental caries in conjunction with the oral cleanliness amongst children suffering from autism in comparison with a control group according to age groups and gender. Materials and Methods: This research involved 30 children aged 3-14 years (male, female) who suffered from autism and attended autism centers in Welfare Children Teaching Hospital in Baghdad province, Iraq, were selected for the study compared to 30 healthy children with the same age group. Plaque (PlI), Decayed, missing, and filled surfaces (dmfs, DMFS), calculus (CI) as well as Gingival (GI) indices have been applied for measuring the status of oral health for these two groups. The data of our research has been analyzed by SPSS 26. Results: The entire autism group was caries active. For primary dentition, a lower dmfs values were recorded for study in comparison with the controls, differences have been not significant in dmfs, while for permanent dentition, a higher DMFS values were recorded for study in comparison with the control group with statistically significant concerning DMFS (P < 0.05). Moreover, caries experience (DS and DMFS) among both genders were higher in the study group in comparison with the controls with a significant difference in female only. Total mean value of PlI in the study group has been greater than the controls with no statistically significant difference. In addition, total mean value of GI in the study group has been lower than the controls with no statistically significant difference. Furthermore, correlation coefficient between the caries experience of primary and permanent teeth with PlI and GI among study and control group showed no significant correlations seen in the study and control groups, all of them were positively correlated except (ds) with (GI) in control group which was negatively correlated with no significant correlation. Conclusion: children with ASD had higher dental caries severity regarding permanent teeth compared to normal subjects, plaque higher in autistic group than control group. Dental care planners must design preventing strategies for avoiding caries; procedures for oral care as well as educational programs for oral care and promotion for addressing diverse challenges facing the oral care in ASD.

scholarly journals Effectiveness of Solifenacin for Managing of Bladder Spasms in Patients With Urethroplasty

2017 ◽  
Vol 11 (5) ◽  
pp. 1580-1587 ◽  
Author(s):  
Xu Feng Peng ◽  
Xiang Guo Lv ◽  
Hong Xie ◽  
Ying Long Sa ◽  
Yue Min Xu ◽  
...  
Keyword(s):  
Term Therapy ◽  
Control Group ◽  
Study Group ◽  
Control Groups ◽  
Short Term ◽  
Suprapubic Cystostomy ◽  
Urine Extravasation ◽  
Vas Scores ◽  
The Mean ◽  
And Control

To evaluate the efficacy and safety of solifenacin in the treatment of bladder spasms after urethroplasty. Patients underwent urethroplasty were randomly assigned to the study group ( n = 165) and the control group ( n = 150). Patients in the study group were treated with solifenacin for 7 days. Patients in the control group were placebo. Each group was further divided into four subgroups: paracentetic suprapubic cystostomy subgroup, traditional suprapubic cystostomy subgroup, former suprapubic cystostomy subgroup, and urethral catheter subgroup. A visual analogue scale (VAS) was used to measure the severity of bladder spasms. The mean duration of spasms, the frequency of spasms, and the incidences of urine extravasation and radiating pain were recorded each day. There were no significant differences in the VAS scores and mean duration of bladder spasms between the study and control groups . However, there was a significantly lower VAS score in the patients taking solifenacin in the paracentetic suprapubic cystostomy subgroup ( p < .05). A similar tendency was noted in the mean duration of bladder spasms in this subgroup. In a comparison of the daily and nightly frequency of spasms within the four subgroups, a significant improvement was noted in the control group within 5 days. A similar difference was not noted within 6 days in the study group. The short-term therapy with solifenacin is an effective and safe method for decreasing the frequency of bladder spasms after urethroplasty. Patients undergoing paracentetic suprapubic cystostomy might be the only subset to benefit from this treatment.

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