Early Results from a Choice Based Conjoint Analysis Assessing Patient Preferences for Selected Features of Erythropoietic Agents.

Blood ◽  
2004 ◽  
Vol 104 (11) ◽  
pp. 5307-5307
Author(s):  
Susan C. Bolge ◽  
John M. Fastenau ◽  
Jamie B. Howell ◽  
Catherine T. Piech ◽  
Jane A. Donohue
Keyword(s):  
Patient Preferences ◽  
Comparative Trial ◽  
Clinical Information ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Early Results ◽  
Transfusion Requirements ◽  
Self Administered Questionnaire ◽  
Anemia Treatment

Abstract Background: Understanding patients’ preferences regarding treatment features is important, as they may not be aligned with those of providers. Epoetin alfa (EPO) and darbepoetin alfa (DARB) are two erythropoietic agents indicated for the treatment of chemotherapy-related anemia (CRA) to increase hemoglobin (Hb) levels and reduce transfusion requirements. These outcomes are associated with fatigue reduction and improved quality of life (QoL), but the degree of improvement and current dosing schedules for both agents may vary. Preliminary results from a comparative trial suggest EPO provides a greater early and overall Hb rise compared to DARB at the commonly prescribed doses (EPO 40,000 units weekly vs. DARB 200 mcg every two weeks) (Proc Am Soc Clin Oncol.2004;23:763 (8153)). Objective: To assess patient preferences for two attributes, effectiveness and convenience, associated with the use of erythropoietic agents. Methods: A cross-sectional study of adults (age 18+) with solid tumor cancers and anemia is on going. 500 planned participants are being recruited through 50 oncologists’ offices across the U.S. Information is collected via a self-administered questionnaire that is divided into two parts. The first, completed by the provider, captures clinical information; the second, completed by patients records their knowledge, experience and preferences regarding anemia and its treatments, including resource use, QoL and productivity. This preliminary analysis focuses on the choice based conjoint (CBC) section of the questionnaire that assesses effectiveness, defined as time to a noticeable relief of fatigue, and convenience, defined as number of provider visits during an 8-week period. Each attribute has three levels (4, 6, and 8 weeks or visits). Results: 276 provider/patient-matched questionnaires have been received. 264 providers and 237 patients have completed the CBC section (96% and 86% response rates, respectively). 80% of providers view time to a noticeable relief of fatigue as being more important to patients than frequency of visits when choosing a medication to treat anemia. Similarly, patients also view time to a noticeable relief of fatigue as being the more important characteristic of anemia medications (1.8 times more important than frequency of visits). For time to a noticeable relief of fatigue, patients prefer an early onset (4 over 6 over 8 weeks). For convenience, patients prefer 8 over 6 over 4 visits during an 8-week period. Conclusion: Providers and patients both view effectiveness as a more important attribute of anemia treatment over convenience. While patients prefer relief of fatigue as soon as possible, interestingly, their preference to see providers more frequently rather than less may be contrary to some providers’ beliefs.

scholarly journals Vision-related Quality of Life in Patients With Glaucoma: the Role of Illness Perceptions

2021 ◽  
Author(s):  
Qiqi Zhang ◽  
Wenzhe Zhou ◽  
Di Song ◽  
Yanqian Xie ◽  
Hao Lin ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Illness Perceptions ◽  
Linear Regression Analysis ◽  
Illness Perception ◽  
Clinical Information ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Illness Perception Questionnaire ◽  
Related Quality

Abstract Purpose: To explore the predictive effect of illness perceptions on vision-related quality of life (VRQoL) in Chinese glaucoma patients.Methods: In this cross-sectional study, 97 patients with glaucoma completed the Brief Illness Perception Questionnaire (BIPQ), the Glaucoma Quality of Life-15 (GQL-15), and a questionnaire with sociodemographic and clinical information. Correlation analysis and hierarchical linear regression analysis were performed.Results: The BIPQ total score was positively correlated with the scores of the total GQL-15 and its four dimensions. Chronic comorbidities, type of glaucoma, best-corrected visual acuity (BCVA), mean defect (MD) of visual field in the better eye, and identity in the BIPQ were the critical predictors of VRQoL. Illness perceptions independently accounted for 7.8% of the variance in the VRQoL of glaucoma patients.Conclusions: Patients with stronger illness perceptions who perceive themselves as having more glaucoma symptoms are likely to experience worse VRQoL. Illness perceptions in glaucoma patients deserve clinical attention, and further studies are needed to examine whether cognitive interventions targeting illness perceptions can improve VRQoL.

scholarly journals Communication and access to information in assessing the quality of multiprofessional care of patients

2010 ◽  
Vol 8 (3) ◽  
pp. 303-307
Author(s):  
Leny Vieira Cavalheiro ◽  
Paola Bruno de Araújo Andreoli ◽  
Nadia Sueli de Medeiros ◽  
Telma de Almeida Busch Mendes ◽  
Roselaine Oliveira ◽  
...  
Keyword(s):  
Quality Of Care ◽  
Healthcare Professionals ◽  
Clinical Information ◽  
Relevant Information ◽  
Cross Sectional Study ◽  
Model Group ◽  
Cross Sectional ◽  
Multiprofessional Team ◽  
Under Performing

ABSTRACT Objective: To assess the quality of a multiprofessional healthcare model for in-hospital patients by means of two performance indicators (communication and knowledge about the case). Methods: A cross-sectional study assessed the knowledge that professionals had about the clinical information of patients and the use of communication strategies by the team. Healthcare professionals were interviewed during their work period. Seven occupational categories were interviewed. A total of 199 medical charts were randomly selected for interviews, and 312 professionals of different categories were interviewed. The sample comprised mostly nurses and physical therapists in the charts that were interviewed. Results: There were no statistically significant differences between the expected performing model group and the under-performing model group for sex, location and job. In the under-performing model group, a larger number of professionals correlated with less knowledge. Communication was improved when nurses had the relevant information about interdisciplinary care (97.4%), appropriate use of the Plan of Care form (97.0%), and formalized discussions with physicians (88.2%). In the expected performing model group, it was observed that the higher the number of healthcare professionals involved, the higher the communication levels. Conclusions: This model of care based on case knowledge and multiprofessional team communication performance indices allowed to assess quality of care. This assessment is measurable and there is the possibility of establishing the quality of care delivered.

scholarly journals The knowledge and perceptions regarding antibiotic stewardship of the interns rotating at the Bloemfontein Academic Complex

2021 ◽  
Vol 63 (1) ◽  
Author(s):  
Anke Archer ◽  
Marna Blom ◽  
Renette De Lange ◽  
Esther Jansen van Vuuren ◽  
Theunis E. Kellerman ◽  
...  
Keyword(s):  
Antibiotic Treatment ◽  
Antibiotic Stewardship ◽  
Cost Effective ◽  
Cross Sectional Study ◽  
Medical Doctors ◽  
Cross Sectional ◽  
E Coli ◽  
Knowledge Based ◽  
Self Administered Questionnaire

Background: Antibiotic resistance (ABR) is a global problem with the overuse of antibiotics accelerating this process. Antibiotic stewardship aims to optimise antibiotic treatment to enable cost-effective therapy and improve patients’ outcome whilst limiting ABR. The study aimed to evaluate intern medical doctors’ knowledge and perceptions about antibiotic stewardship and their perceptions regarding education on relevant topics.Methods: This was a cross-sectional study on interns rotating at Bloemfontein Academic Complex. An anonymous, self-administered questionnaire was completed. The questionnaire recorded demographic information, perception and knowledge of antibiotic stewardship, and the quality of education as perceived by the interns.Results: Of the 120 possible participants, 92 (76.7%) responded to all or part of the questionnaire. The median age of the respondents was 25 years, and 56.7% of the respondents were female. The mean score for the knowledge-based case scenarios was 5.4 out of 10. Only 4.4% participants could manage a drip site infection correctly, whilst 18.5% could treat Escherichia coli (E. coli) bacteraemia. The interns perceived that they have a lack of training and preparedness in certain areas of prescribing antibiotics. Though 77.2% of the interns had received education on starting antibiotic treatment, 29.3% claimed to be unsure when to start antibiotic therapy. Interns indicated that formal lectures (81.3%) and bedside tutorials (86.7%) have a high educational value.Conclusion: Intern medical doctors do not have sufficient knowledge to establish antibiotic stewardship but have a desire for improvement. The results identified specific areas where better antibiotic training is required.

scholarly journals The Impact of Pediatric Epilepsy on Children and Families: A Multicenter Cross-Sectional Study

2018 ◽  
Vol 14 (1) ◽  
pp. 323-333 ◽  
Author(s):  
Ahmed Hussein Subki ◽  
Abdel Moniem Mukhtar ◽  
Rakan Salah Al-Harbi ◽  
Abdulaziz Khaled Alotaibi ◽  
Faisal Ghazi Mosaad ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cross Sectional Study ◽  
Pediatric Epilepsy ◽  
Children And Families ◽  
Cross Sectional ◽  
The Family ◽  
The Mean ◽  
The Impact ◽  
Self Administered Questionnaire

Background and Objectives: Epilepsy is considered one of the most prevalent causes of morbidity in children. The aim of this study is to determine how epilepsy impacts the lives of children with epilepsy and their families. Methods: A translated version of the “Impact of Pediatric Epilepsy Scale” (IPES) questionnaire was completed by the 80 mothers of children with epilepsy, recruited at three hospitals in Jeddah, Saudi Arabia This is a validated self-administered questionnaire used to assess the impact of epilepsy on the lives of the child and family, as well as the quality of life (QoL) of the child. Results: The mean age of children epilepsy was 6.32 years (SD = 3.22). The mean IPES score was 6.28 (SD = 8.42) and the mean child’s QoL was 2.85 (SD= 0.83). 87.5% of the mothers rated their child’s QoL as low. IPES score was significantly associated with cause of seizure (β=0.259; 95%-CI= 0.263 - 10.334; p = 0.039). Child’s QoL was significantly associated with frequency of seizure (β=0.251; 95%-CI= 0.016 - 0.568; p= 0.039) and child’s nationality (β=-0.270; 95%-CI -0.252, -0.013; p= 0.031). Conclusions: Pediatric epilepsy may have a greater impact on the lives of the child and the family when it is not comorbid with cerebral palsy. Quality of life tends to be lower for non-Saudi children, and children with more frequent seizures. Therefore, these groups may need more support in managing the impact that epilepsy has on their daily functioning and quality of life.

scholarly journals Health indicators associated with poor sleep quality among university students

2014 ◽  
Vol 48 (6) ◽  
pp. 1085-1092 ◽  
Author(s):  
Márcio Flávio Moura de Araújo ◽  
Roberto Wagner Júnior Freire de Freitas ◽  
Adman Câmara Soares Lima ◽  
Dayse Christina Rodrigues Pereira ◽  
Maria Lúcia Zanetti ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Undergraduate Students ◽  
Clinical Laboratory ◽  
Demographic Data ◽  
Health Indicators ◽  
Cross Sectional Study ◽  
Poor Sleep ◽  
Cross Sectional ◽  
Self Administered Questionnaire

Objective To associate the sleep quality of Brazilian undergraduate students with health indicators. Method A cross-sectional study was developed with a random sample of 662 undergraduate students from Fortaleza, Brazil. The demographic data, Pittsburgh Sleep Quality Index and health data indicators (smoking, alcoholism, sedentary lifestyle, nutritional condition and serum cholesterol) were collected through a self-administered questionnaire. Blood was collected at a clinical laboratory. In order to estimate the size of the associations, a Poisson Regression was used. Results For students who are daily smokers, the occurrence of poor sleep was higher than in non-smokers (p<0.001). Prevalence rate values were nevertheless close to 1. Conclusion The likelihood of poor sleep is almost the same in smokers and in alcoholics.


scholarly journals Health status and quality of life in patients with severe hemophilia A: A cross-sectional survey

2019 ◽  
Vol 11 (2) ◽  
Author(s):  
Majid Davari ◽  
Zahra Gharibnaseri ◽  
Roya Ravanbod ◽  
Abolfazl Sadeghi
Keyword(s):  
Quality Of Life ◽  
Hemophilia A ◽  
Clinical Information ◽  
Cross Sectional Study ◽  
Adult Patients ◽  
Severe Hemophilia ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
The Mean

Among different groups of hemophiliacs, those suffering from Severe Hemophilia A (SHA) are most vulnerable to the complications of the disease. This study investigated the Health-Related Quality of Life (HR-QoL) among adult patients with SHA. A cross-sectional study was designed to gather demographic and clinical information from adult patients with SHA. Patients with inhibitors were excluded. The remaining were asked to complete the HR-QoL questionnaire after being examined for joint health using the Hemophilia Joint HealthScore (HJHS). The HR-QoL and joint conditions were measured in 38 patients. The mean EQ-5D value scores were 0.46 (SD=0.23) while the mean Visual Analogous Scale score was 50 (SD=18.7). The clinical examination of patients indicated that the HJHS were as follows: eight patients had a score of 55-75, 12 patients had a score of 40-55, 7 of them (25-40) and 11 patients had a score of 10-25. The results obtained from this study showed that HR-QoL in hemophilia patients was considerably low. Pain, anxiety/depression, and motion limitations were the main causes of the disutility for these patients respectively.

scholarly journals Leg cramps, its associated factors and quality of life among pregnant mothers: A cross-sectional study in a Malaysian suburban health clinic

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 1600-1608
Author(s):  
Sharifah Najwa Syed Mohamad ◽  
Saharuddin Ahmad ◽  
Hizlinda Tohid
Keyword(s):  
Quality Of Life ◽  
Cross Sectional Study ◽  
Health Clinic ◽  
Sectional Study ◽  
Cross Sectional ◽  
Assessment And Treatment ◽  
Convenience Sampling ◽  
Self Administered Questionnaire ◽  
Pregnant Mothers

Leg cramps (LCs) are common in pregnancy and may affect pregnant mothers' quality of life (QoL). However, studies to show this impact are still lacking. Thus, this study aimed to evaluate the association of LCs with QoL among pregnant mothers. The magnitude and characteristics of LCs were assessed too. A cross-sectional study was conducted at a government health clinic in Hulu Langat, Selangor involving 99 mothers in their second or third trimesters, recruited through convenience sampling between March and April 2018. This study used a developed bilingual (Bahasa Malaysia and English) self-administered questionnaire on leg cramps profile, as well as the bilingual self-administered SF-12v2, to assess their QoL. About 71.7% experienced LCs during this pregnancy. About half experienced LCs once to twice a week and 63.4% had moderately painful LCs. Only 26.7% had severely painful LCs and 12.7% had the next-day soreness in all or most of the time. Gestational age (P=0.001) and booking Body Mass Index (BMI) (p=0.022) were significantly associated with LCs, but not their QoL (p=0.712 for PCS and p=0.118 for MCS). Generally, LCs were common among these pregnant mothers. However, LCs appear to be brief, infrequent, and mild which did not significantly affect their QoL. Nevertheless, LCs should not be disregarded, as a subgroup of them experienced severe LCs with the next day soreness who may need further assessment and treatment.

scholarly journals Clinicians’ Perceived Understanding of Biostatistical Results in the Medical Literature: A Cross-Sectional Study

Medicina ◽  
2019 ◽  
Vol 55 (6) ◽  
pp. 227
Author(s):  
Kurubaran Ganasegeran ◽  
Alan Swee Hock Ch’ng ◽  
Mohd Fadzly Amar Jamil ◽  
Irene Looi
Keyword(s):  
Statistical Methods ◽  
Medical Literature ◽  
Clinical Information ◽  
Cross Sectional Study ◽  
Evidence Based ◽  
Sectional Study ◽  
Cross Sectional ◽  
Information Exploration ◽  
Based Medicine ◽  
Self Administered Questionnaire

Background and objectives: The continuum of evidence-based medicine (EBM) depends solely on clinicians’ commitment to keep current with the latest clinical information. Exploration on clinicians’ understanding of biostatistical results in the medical literature is sparse to date. This study aimed to evaluate clinicians’ perceived understanding of biostatistical results in the medical literature and the factors influencing them. Materials and Methods: A cross-sectional study was conducted among 201 clinicians at the Seberang Jaya Hospital, a cluster-lead research hospital in Northern Malaysia. A self-administered questionnaire that consisted of items on sociodemographics, validated items on clinicians’ confidence level in interpreting statistical concepts, perceived understanding of biostatistics, and familiarity with different statistical methods were used. Descriptive, univariate, and multivariate analyses were conducted. Results: Perceived understanding of biostatistical results among clinicians in our sample was nearly 75%. In the final regression model, perceived understanding was significantly higher among clinicians who were able to interpret p-values with complete confidence (AOR = 3.0, 95% CI 1.1–8.1), clinicians who regularly encounter measures of central tendencies (AOR = 2.3, 95% CI 1.1–5.2), and clinicians who regularly encounter inferential statistics (AOR = 2.2, 95% CI 1.1–4.5) while appraising the medical literature. Conclusions: High perceived understanding was significantly associated with clinicians’ confidence in interpreting statistical concepts and familiarity with different statistical methods. Our findings form a platform to understand clinicians’ ability to appraise rigorous biostatistical results in the medical literature for the retrieval of evidence-based data to be used in routine clinical practice.

scholarly journals Prevalence and Clinical Features of FOG in Chinese PD Patients, a Multicenter and Cross-Sectional Clinical Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Jing Gan ◽  
Weiguo Liu ◽  
Xuebing Cao ◽  
Anmu Xie ◽  
Wentao Li ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Features ◽  
Freezing Of Gait ◽  
Clinical Information ◽  
Binary Logistic Regression ◽  
Cross Sectional Study ◽  
Unique Contribution ◽  
Cross Sectional ◽  
Wide Range

Objectives: Freezing of gait (FOG) is generally considered as an independent symptom of Parkinson's disease (PD) with a complex pathophysiology. There is a wide range of associated clinical features of FOG reported from different studies without consistent conclusion. Thus, a multicenter, cross-sectional study was designed to investigate the prevalence and clinical features of FOG together with its unique contribution quality of life in Chinese PD patients.Methods: Eight hundred and thirty eight PD patients were consecutively recruited into this study from 12 hospital centers in six provinces in China. Clinical information, including motor and neuropsychological features as well as pharmacological details, was collected.Results: Of 827 PD patients, 245 (29.63%) reported FOG. The prevalence of FOG was strongly correlated with modified H-Y stages and symptomatic duration (p &lt; 0.01). 84.90% freezers experienced FOG during turning and 88.98% experienced when initiating the first step. Compared with non-freezers, freezers reported longer disease duration (7.73 ± 5.44 vs. 4.69 ± 3.94, p &lt; 0.000), higher frequent PIGD phenotype (61.22 vs. 35.91%, p &lt; 0.000), higher scores of UPDRS III (32.85 ± 15.47 vs. 22.38 ± 12.89, p &lt; 0.000), HAMA (10.99 ± 7.41 vs. 7.59 ± 6.47, p &lt; 0.000), HAMD (15.29 ± 10.29 vs. 10.58 ± 8.97, p &lt; 0.000) and lower MMSE score (25.12 ± 5.27 vs. 26.63 ± 3.97, p &lt; 0.000), and higher daily levodopa dosage (432.65 ± 264.31 vs. 319.19 ± 229.15, p &lt; 0.000) with less frequent initial use of dopaminergic agonist (8.57 vs. 14.78%, p &lt; 0.05). Using binary logistic regression, the associated factors of FOG might be non-tremor dominant onset (OR = 3.817, p &lt; 0.000), the presence of anxiety (OR = 2.048, p &lt; 0.000) and imbalance (OR = 4.320, p = 0.012). Freezers had poorer quality of life than non-freezers and FOG impacted PDQ-8 independently.Conclusion: Nearly one third of the PD patients experienced FOG. Its frequency increased with PD progression and FOG reduced independently the quality of life. Non-tremor dominant, disease progression, and anxiety were risk factors of FOG.

scholarly journals Lifestyle and risk behaviors for chronic noncommunicable diseases among healthcare undergraduates in Midwest, Brazil

2021 ◽  
Vol 26 (7) ◽  
pp. 2911-2920
Author(s):  
Luciana Zaranza Monteiro ◽  
Andrea Ramirez Varela ◽  
Bruno Alves de Lira ◽  
Suliane Beatriz Rauber ◽  
Juliana Oliveira de Toledo ◽  
...  
Keyword(s):  
University Students ◽  
Risk Behaviors ◽  
Cross Sectional Study ◽  
Demographic Variables ◽  
Noncommunicable Diseases ◽  
Cross Sectional ◽  
Undergraduate University Students ◽  
Perception Of Health ◽  
Self Administered Questionnaire

Abstract This study aimed to assess the lifestyle of undergraduate university students, and to investigate the prevalence of risk behaviors for chronic noncommunicable diseases. This cross-sectional study took place in Brasilia, with 2.163 healthcare undergraduates. We used a self-administered questionnaire for demographic variables, social class, behavioral data, self-perception of health and self-reported diseases. Given a total of 2.163 students, 69.3% were female, 65.4% were 20-29 years, men smoked more cigarettes (p < 0.01) and used more alcohol than women. We found significant differences in the consumption of beans (p < 0.04) and full-fat milk (p < 0.01) between females and males. Women also had more sedentary lifestyles (p < 0.01) and showed higher prevalences of overweight (33.8%) and obesity (5.0%). Students who did not engage in physical activity were more morbidities, overweight (p = 0.03), consumed more soft drinks (p < 0.01) and meat with excess fat (p = 0.01). University students were found to have unhealthy lifestyles. There is an urgent need for both a formulation and implementation of public health policies to promote health and improve student quality of life (QoL).

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