Maternal antibiotic use and child asthma: is the association causal?

Introduction: Healthcare associated infections and antimicrobial use are common among residents of long-term care facilities. Faced to the lack of standardized data, the European Centre for Disease Prevention and Control funded a project with the aim of estimating prevalence of infections and antibiotic use in European long-term care facilities. Aim: The aim of the authors was to present the results of the European survey which were obtained in Hungary. Method: In Hungary, 91 long-term care facilities with 11,823 residents participated in the point-prevalence survey in May, 2013. Results: The prevalence of infections was 2.1%. Skin and soft tissues infections were the most frequent (36%), followed by infections of the respiratory (30%) and urinary tract (21%). Antimicrobials were mostly prescribed for urinary tract infections (40.3%), respiratory tract infections (38.4%) and skin and soft tissue infections (13.2%). The most common antimicrobials (97.5%) belonged to the ATC J01 class of “antibacterials for systemic use”. Conclusions: The results emphasise the need for a national guideline and education for good practice in long-term care facilities. Orv. Hetil., 2014, 155(23), 911–917.

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Testing for resistance: Point-of-care testing as a communicational tool in antibiotic prescribing

Communication & Medicine ◽

10.1558/cam.32191 ◽

2018 ◽

Vol 14 (3) ◽

pp. 229-240

Author(s):

Johanna Lindell

Keyword(s):

Point Of Care ◽

Rapid Test ◽

Antibiotic Use ◽

Treatment Recommendation ◽

Antibiotic Prescribing ◽

Communicative Practices ◽

Effective Strategies ◽

Reactive Protein ◽

Point Of Care Test ◽

Test Result

As antibiotic resistance becomes a growing health emergency, effective strategies are needed to reduce inappropriate antibiotic use. In this article, one such strategy – communicative practices associated with the C-reactive protein point-of care test – is investigated. Building on a collection of 31 videorecorded consultations from Danish primary care, and using conversation analysis, this study finds that the rapid test can be used throughout the consultation to incrementally build the case for a nonantibiotic treatment recommendation, both when the test result is forecast and reported. The study also finds that the format of reports of elevated results differs from that of ‘normal’ results, resulting in a subtle shift of authority from doctor to test.

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Efficiency of β-glucan utilisation in fish culture

Tạp chí Khoa học và Công nghệ Biển ◽

10.15625/1859-3097/19/4a/14583 ◽

2019 ◽

Vol 19 (4A) ◽

pp. 167-174

Author(s):

Do Huu Hoang

Keyword(s):

Human Health ◽

Stress Resistance ◽

Antibiotic Use ◽

Fish Culture ◽

Growth Promoter ◽

Sustainable Aquaculture ◽

Major Benefit

In the last three decades aquaculture is a rapidly developing sector worldwide and antibiotics are used popularly as growth promoter. Antibiotic use was banned because research proved that antibiotic has caused many effects on environment and human health. Therefore, finding antibiotic alternatives is the first priority. The most prospect products today are probiotic and prebiotic. β-glucan is one of the immunostimulants which showed a variety of benefits to the health of many aquaculture species. In this paper only the results of β-glucan, a kind of prebiotic supplied in aquaculture, were summarized. The major benefit of β-glucan are to boost growth, to reduce mortality, to enhance tolerance or stress resistance to environmental or pathogen challenges. Although the applications of β-glucan are popular worldwide, its use in aquaculture in Vietnam is still limited. This paper provides an important reference for β-glucan utilisation which may help to develop a sustainable aquaculture in Vietnam.

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Is perioperative antibiotic necessary in straightforward implant placement procedures?

Journal of Oral Implantology ◽

10.1563/aaid-joi-d-19-00282 ◽

2020 ◽

Author(s):

Elçin Bedeloğlu ◽

Mustafa Yalçın ◽

Cenker Zeki Koyuncuoğlu

Keyword(s):

Clavulanic Acid ◽

Dental Implant ◽

Prophylactic Antibiotic ◽

Antibiotic Use ◽

Implant Failure ◽

Control Group ◽

Implant Placement ◽

Significant Difference ◽

Amoxicillin Clavulanic Acid ◽

Experimental Group

The purpose of this non-random retrospective cohort study was to evaluate the impact of prophylactic antibiotic on early outcomes including postoperative pain, swelling, bleeding and cyanosis in patients undergoing dental implant placement before prosthetic loading. Seventy-five patients (45 males, 30 females) whose dental implant placement were completed, included to the study. Patients used prophylactic antibiotics were defined as the experimental group and those who did not, were defined as the control group. The experimental group received 2 g amoxicillin + clavulanic acid 1 h preoperatively and 1 g amoxicillin + clavulanic acid twice a day for 5 days postoperatively while the control group had received no prophylactic antibiotic therapy perioperatively. Data on pain, swelling, bleeding, cyanosis, flap dehiscence, suppuration and implant failure were analyzed on postoperative days 2, 7, and 14 and week 12. No statistically significant difference was detected between the two groups with regard to pain and swelling on postoperative days 2, 7, and 14 and week 12 ( p >0.05), while the severity of pain and swelling were greater on day 2 compared to day 7 and 14 and week 12 in both groups ( p =0.001 and p <0.05, respectively). Similarly, no significant difference was found between the two groups with regard to postoperative bleeding and cyanosis. Although flap dehiscence was more severe on day 7 in the experimental group, no significant difference was found between the two groups with regard to the percentage of flap dehiscence assessed at other time points. Within limitations of the study, it has been demonstrated that antibiotic use has no effect on implant failure rates in dental implant surgery with a limited number of implants. We conclude that perioperative antibiotic use may not be required in straightforward implant placement procedures. Further randomized control clinical studies with higher numbers of patients and implants are needed to substantiate our findings.

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