scholarly journals Energy expenditure and physical activity in COPD by the DLW method and an accelerometer

2021 ◽  
pp. 00407-2020
Author(s):  
Hideaki Sato ◽  
Hidetoshi Nakamura ◽  
Yuki Nishida ◽  
Toru Shirahata ◽  
Sanehiro Yogi ◽  
...  

Although weight loss suggests poor prognosis of COPD, only a few studies have examined total energy expenditure (TEE) or physical activity level (PAL) using the doubly labeled water (DLW) method. We evaluated TEE and PAL using the DLW method together with a triaxial accelerometer to elucidate the relationships between TEE, PAL and clinical parameters leading to a practical means of monitoring COPD physical status.This study evaluated 50- to 79-year-old male patients with mild to very severe COPD (n=28) or at risk for COPD (n=8). TEE, activity energy expenditure for 2 weeks, and basal metabolic rate were measured by DLW, an accelerometer, and indirect calorimetry, respectively. All patients underwent pulmonary function, chest-computed tomography, 6-min walk, body composition and grip strength (GS) tests. Relationships between indices of energy expenditure and clinical parameters were analysed. Bland-Altman analysis was used to examine the agreement of TEE and PAL between the DLW method and the accelerometer.TEE and PAL using DLW in the total population were 2273±445 kcal·day−1 and 1.80±0.20, respectively. TEE by DLW was correlated well with that from the accelerometer and GS (p<0.0001), and PAL by DLW correlated well with that from the accelerometer (p<0.0001), GS and 6-min walking distance (p<0.001) among various clinical parameters. The accelerometer, however, underestimated TEE (215±241 kcal·day−1) and PAL (0.18±0.16), with proportional biases in both indices.TEE and PAL can be estimated by the accelerometer in patients with COPD if systematic errors and relevant clinical factors such as muscle strength and exercise capacity are accounted for.

2019 ◽  
Vol 25 (2) ◽  
pp. 116-120
Author(s):  
Luiz Antonio dos Anjos ◽  
Bruna de Andrade Messias da Silva ◽  
Vivian Wahrlich

ABSTRACT Objective: To assess the physical activity level (PAL) and the total daily energy expenditure (EE-TDEE) in a sample of ≥60y subjects from Niterói, Rio de Janeiro, Brazil. Methods: A convenience sample of 88 subjects recruited from recreational physical activity programs wore an accelerometer around the waist for seven consecutive days for at least 10h/day. Minute-by-minute EE was estimated from the counts per minute (CPM) data, and the daily sum yielded the TDEE. PAL (TDEE/BMR) with BMR calculated with the FAO/WHO predictive equation and a population-specific equation. Body composition was assessed by DXA. Results: Mean age (SD) was 69.2 (5.8) years, the prevalence of overweight and obesity was 36.4 and 25.0%, respectively, and excess body fat was 39.8%. The subjects spent 600min/day engaged in sedentary activities (CPM<100). Men engaged in 30min of moderate-to-vigorous physical activity (CPM≥1,952) daily, on average. The subjects were active on 34.5 and 18.0% of the weekdays and weekend days with a 1,400 steps/day difference between these days. TDEE was 1,731.5 (348.7) and 1,356.3 (223.7) kcal/day depending on the BMR prediction equation used. Mean PAL was lower than the maintenance level. Conclusions: The high prevalence of sedentary activities and the low percentage of subjects who met the physical activity recommendations indicate that physical activity programs must be adjusted so that the enrolled subjects can meet the physical activity recommendations, preferably with the activities objectively monitored. Population-specific equations improve the final estimation of TDEE and PAL. Level of Evidence I; Diagnostic studies - Investigating a diagnostic test.


2003 ◽  
Vol 62 (3) ◽  
pp. 645-650 ◽  
Author(s):  
Klaas R. Westerterp

Activity intensity is a potential determinant of activity-induced energy expenditure. Tri-axial accelerometery is the most objective measurement technique for the assessment of activity intensity, in combination with doubly-labelled water for the measurement of energy expenditure under free-living conditions. Data on the effects of subject characteristics, including body size and age, and exercise training on the relationship between activity intensity and daily energy expenditure are reviewed. Average daily metabolic rate and non-basal energy expenditure are positively related to body size. The duration and intensity of physical activities do not need to be equivalent to the energy spent on activity. Obese subjects spend more energy on physical activity but can perform fewer activities, especially high-intensity (weight-bearing) activities, because of their higher body weight. Physical activity generally declines gradually from about 60 years of age onwards. Most subjects >80 years have an activity level well below the level defined for sedentary middle-aged adults. Spending relatively more time on low-intensity activities has a negative effect on the mean physical activity level. To obtain a higher physical activity level does not necessarily imply high-intensity activities. In an average subject 25% of the activity-induced energy expenditure may be attributed to high-intensity activities. Exercise training, as a form of high-intensity activity, affects the physical activity level more in younger subjects than in elderly subjects.


1996 ◽  
Vol 91 (2) ◽  
pp. 241-245 ◽  
Author(s):  
N. I. J. Paton ◽  
M. Elia ◽  
S. A. Jebb ◽  
G. Jennings ◽  
D. C. MacAllan ◽  
...  

1. Our objectives were to measure total energy expenditure, the daily variation in total energy expenditure and the physical activity level in a group of HIV-positive subjects using the bicarbonate-urea method. The study also aimed to assess the practicalities of using the bicarbonate-urea technique in free-living conditions. 2. Total energy expenditure was measured with the bicarbonate-urea method over 2 consecutive days (1 day in one subject) in 10 male patients with HIV infection (median CD4 count = 30). Resting energy expenditure was measured by indirect calorimetry. Physical activity level (total energy expenditure/resting energy expenditure) was calculated from these measurements and from activity diaries. 3. Resting energy expenditure was found to be 7.46 ± 0.87 MJ/day, 5% higher than predicted values. Total energy expenditure was 10.69 ± 1.95 MJ/day with an intra-individual day-to-day variation of 6 ± 6%. The measured physical activity level was 1.42 ± 0.14, higher than the diary estimate of 1.34 ± 0.16 (P = 0.029), and there were large inter-method differences in individual values. The subcutaneous infusion of bicarbonate was well tolerated and did not seem to restrict normal activities. 4. Total energy expenditure was not elevated in the group of HIV-positive subjects when compared with reference values for normal subjects. The physical activity level of the patients in this study was lower than that measured using other techniques in healthy young men, but was compatible with that expected for people leading a sedentary lifestyle. Reductions in physical activity in patients with HIV are likely to contribute to the wasting process and physical activity level may thus be a clinically useful measure. This study has also provided the first tracer estimate of the day-to-day variation in total energy expenditure. The bicarbonate-urea method represents an important new investigative tool for measuring total energy expenditure which has previously only been possible within the confines of a whole-body calorimeter or using the expensive doubly labelled water method.


2003 ◽  
Vol 90 (3) ◽  
pp. 643-649 ◽  
Author(s):  
Margriet S. Westerterp-Plantenga ◽  
Annelies H. C. Goris ◽  
Erwin P. Meijer ◽  
Klaas R. Westerterp

Habitual meal frequency was assessed as a possible function of components of energy expenditure (EE) in human subjects. Fifty-six subjects participated (four categories differing in body composition): ten older women (fat-free mass (FFM) 42·0 (sd 6·3) kg, aged 59 (sd 2) years, BMI 27·5 (sd 6·9) kg/m2), fifteen younger women (FFM 45·5 (sd 5·2) kg, aged 34 (sd 10) years, BMI 21·9 (sd 2·3) kg/m2), twelve older men (FFM 56·8 (sd 5·9) kg, aged 62 (sd 4) years, BMI 25·7 (sd 3·3) kg/m2) and nineteen younger men (FFM 63·9 (sd 7·5) kg, aged 23·1 (sd 3·9) years, BMI 22·9 (sd 1·8) kg/m2). Measurements consisted of habitual meal frequency by validated food-intake diaries, physical activity by tri-axial accelerometers and resting EE by a ventilated hood system. Habitual meal frequency was expressed as a function of resting EE (including resting EE as a function of FFM), and of activity-induced EE, using regression analysis. FFM differed according to gender and age categories (P < 0·01). Physical activity level was higher in the younger men than in the other categories (P < 0·05). No relationship of meal frequency with the variables assessed was observed in subjects with a low FFM (the women). In the subjects with a medium FFM (the older men), meal frequency was positively related to resting EE (r2 0·4, P < 0·05), but not to the residuals of resting EE as a function of FFM, and inversely related to activity-induced EE (r2 0·3, P < 0·05). Resting EE explained 40% of the variation in meal frequency; adding activity-induced EE increased this to 60%. In the subjects with a high FFM (the younger men), meal frequency was inversely related to resting EE (r2 0·8, P < 0·0001) and to the residuals of resting EE as a function of FFM (P = 0·03), and positively related to activity-induced EE (r2 0·6, P < 0·0001). Resting EE explained 85% of the variation in meal frequency; adding activity-induced EE increased this to 89%. Habitual meal frequency was a function of components of EE, namely resting EE and activity-induced EE, only in subjects with a medium to high FFM (men). FFM-related differences in these relationships suggest a role of physical activity.


1997 ◽  
Vol 127 (2) ◽  
pp. 299-305 ◽  
Author(s):  
Nancy F. Butte ◽  
Lourdes Barbosa ◽  
Salvador Villalpando ◽  
William W. Wong ◽  
E. O. Smith

1999 ◽  
Vol 2 (3a) ◽  
pp. 335-339 ◽  
Author(s):  
Marleen A. Van Baak

AbstractEnergy expenditure rises above resting energy expenditure when physical activity is performed. The activity-induced energy expenditure varies with the muscle mass involved and the intensity at which the activity is performed: it ranges between 2 and 18 METs approximately. Differences in duration, frequency and intensity of physical activities may create considerable variations in total energy expenditure. The Physical Activity Level (= total energy expenditure divided by resting energy expenditure) varies between 1.2 and 2.2–2.5 in healthy adults. Increases in activity-induced energy expenditure have been shown to result in increases in total energy expenditure, which are usually greater than the increase in activity-induced energy expenditure itself. No evidence for increased spontaneous physical activity, measured by diary, interview or accelerometer, was found. However, this does not exclude increased physical activity that can not be measured by these methods. Part of the difference may also be explained by the post-exercise elevation of metabolic rate.If changes in the level of physical activity affect energy balance, this should result in changes in body mass or body composition. Modest decreases of body mass and fat mass are found in response to increases in physical activity, induced by exercise training, which are usually smaller than predicted from the increase in energy expenditure. This indicates that the training-induced increase in total energy expenditure is at least partly compensated for by an increase in energy intake. There is some evidence that the coupling between energy expenditure and energy intake is less at low levels of physical activity. Increasing the level of physical activity for weight loss may therefore be most effective in the most sedentary individuals.


2005 ◽  
Vol 93 (2) ◽  
pp. 199-203 ◽  
Author(s):  
Klaas R. Westerterp ◽  
Guy Plasqui ◽  
Annelies H. C. Goris

Although water is an important nutrient, there are no recommended intake values. Here, water intake, energy intake, physical activity and water loss was measured over 1 week in summer and in winter. Subjects were healthy volunteers, forty-two women and ten men, mean age of 29 (sd 7) years and mean BMI 21·8 (sd 2·2) kg/m2. Water intake was measured with a 7 d food and water record. Physical activity level (PAL) was observed as the ratio of total energy expenditure, as measured with doubly labelled water, to resting energy expenditure as measured in a respiration chamber. Water loss was measured with the deuterium elimination method. Water loss was highly reproducible and ranged from 0·20 to 0·35 l/MJ, independent of season and activity level, with higher values in women. Water loss was related to water and energy intake in summer (r 0·96, P<0·0001 and r 0·68, P<0·001, respectively) as well as in winter (r 0·98, P<0·0001 and r 0·63, P<0·01, respectively). Water loss was, for men, higher in subjects with a higher physical activity in summer (r 0·94, P<0·0001) and in winter (r 0·70, P<0·05). Normalizing water loss for differences in energy expenditure by expressing water loss in litres per MJ resulted in the same value for men in summer and winter. For women, physical activity-adjusted values of water loss were higher, especially in summer. In men, water turnover was determined by energy intake and physical activity, while seasonal effects appeared through energy expenditure. Women showed a higher water turnover that was unrelated to physical activity.


2012 ◽  
Vol 113 (10) ◽  
pp. 1530-1536 ◽  
Author(s):  
Robert Ojiambo ◽  
Kenn Konstabel ◽  
Toomas Veidebaum ◽  
John Reilly ◽  
Vera Verbestel ◽  
...  

One of the aims of Identification and Prevention of Dietary- and Lifestyle-Induced Health Effects in Children and Infants (IDEFICS) validation study is to validate field measures of physical activity (PA) and energy expenditure (EE) in young children. This study compared the validity of uniaxial accelerometry with heart-rate (HR) monitoring vs. triaxial accelerometry against doubly labeled water (DLW) criterion method for assessment of free-living EE in young children. Forty-nine European children (25 female, 24 male) aged 4–10 yr (mean age: 6.9 ± 1.5 yr) were assessed by uniaxial ActiTrainer with HR, uniaxial 3DNX, and triaxial 3DNX accelerometry. Total energy expenditure (TEE) was estimated using DLW over a 1-wk period. The longitudinal axis of both devices and triaxial 3DNX counts per minute (CPM) were significantly ( P < 0.05) associated with physical activity level (PAL; r = 0.51 ActiTrainer, r = 0.49 uniaxial-3DNX, and r = 0.42 triaxial Σ3DNX). Eight-six percent of the variance in TEE could be predicted by a model combining body mass (partial r2 = 71%; P < 0.05), CPM-ActiTrainer (partial r2 = 11%; P < 0.05), and difference between HR at moderate and sedentary activities (ModHR − SedHR) (partial r2 = 4%; P < 0.05). The SE of TEE estimate for ActiTrainer and 3DNX models ranged from 0.44 to 0.74 MJ/days or ∼7–11% of the average TEE. The SE of activity-induced energy expenditure (AEE) model estimates ranged from 0.38 to 0.57 MJ/day or 24–26% of the average AEE. It is concluded that the comparative validity of hip-mounted uniaxial and triaxial accelerometers for assessing PA and EE is similar.


2005 ◽  
Vol 8 (7a) ◽  
pp. 940-952 ◽  
Author(s):  
Anna Ferro-Luzzi

AbstractObjectiveIn anticipation of the revision of the 1985 Food and Agricultural Organization/World Health Organization/United Nations University (FAO/ WHO/UNU) Expert Consultation Report on ‘Energy and Protein Requirements’, recent scientific knowledge on the principles underlying the estimation of energy requirement is reviewed.DesignThis paper carries out a historical review of the scientific rationale adopted by previous FAO/WHO technical reports on energy requirement, discusses the concepts used in assessing basal metabolic rate (BMR), energy expenditure, physical activity level (PAL), and examines current controversial areas. Recommendations and areas of future research are presented.ConclusionsThe database of the BMR predictive equations developed by the 1985 FAO/WHO/UNU Expert Consultation Report on Energy and Protein Requirements needs updating and expansion, applying strict and transparent selection criteria. The existence of an ethnic/tropical factor capable of affecting BMR is not supported by the available evidence. The factorial approach for the calculation of energy requirement, as set out in the 1985 report, should be retained. The estimate should have a normative rather than a prescriptive nature, except for the allowance provided for extra physical activity for sedentary populations, and for the prevention of non-communicable chronic diseases. The estimate of energy requirement of children below the age of 10 years should be made on the basis of energy expenditure rather than energy intake. The evidence of the existence of an ethnic/tropical factor is conflicting and no plausible mechanism has as yet been put forward.


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