scholarly journals Dietary intake of fish, omega-3, omega-6 polyunsaturated fatty acids and vitamin D and the prevalence of psychotic-like symptoms in a cohort of 33 000 women from the general population

2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Maria Hedelin ◽  
Marie Löf ◽  
Marita Olsson ◽  
Tommy Lewander ◽  
Björn Nilsson ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Vitamin D ◽  
General Population ◽  
Polyunsaturated Fatty Acids ◽  
Dietary Intake ◽  
Omega 3 ◽  
Omega 6 ◽  
3 Omega

Suplementação de Ácidos Graxos Poli-insaturados de cadeia longa durante a gestação e fatores associados ao desenvolvimento infantil

2021 ◽  
Vol 11 (1) ◽  
pp. e5736
Author(s):  
Tanuzy de Almeida Souza ◽  
Leila Magda Rodrigues Almeida ◽  
Cinthia Soares Lisboa
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Child Growth ◽  
Primary Role ◽  
Omega 3 ◽  
Before And After ◽  
Omega 6 ◽  
The Central Nervous System ◽  
3 Omega ◽  
Long Chain

O objetivo deste estudo é descrever os benefícios do consumo dos ácidos graxos poli-insaturados durante a gestação e fatores associados no desenvolvimento infantil. Trata-se de uma revisão bibliográfica integrativa, a partir da análise de artigos científicos indexados nas bases de dados MedLine, Scielo, Science Direct e Google acadêmico, com recorte temporal de dez anos (2010-2020). Os descritores utilizados foram: ácido graxopoli-insaturados de cadeia longa; ômega 3; ômega 6; gestante e lactente, no idioma português e inglês, com o auxílio do operador boleano “AND”. Os resultados da pesquisa, após os critérios de inclusão e exclusão, obtiveram um total de 12 artigos. Os estudos demonstraram que os ácidos graxos poli-insaturados de cadeia longa (LCPUFA), tais como os das séries ômega 3 e ômega 6, em especial ácido docosahexaenóico e ácido eicosapentaenóico são fundamentais para o crescimento e desenvolvimento infantil, e tem função primordial na formação e no funcionamento do sistema nervoso central e da retina, e melhora do peso ao nascer. Além disso, os LCPUFA atuam nas gestantes reduzindo riscos de prematuridade, possui função antiinflamatória e antioxidante, reduz o estresse oxidativo, e controla os sintomas depressivos pré e pós-gestação. Conduto, são necessários mais estudos que abordem as quantidades adequadas para o período gestacional favorável à saúde materno-infantil.AbstractThis study aims to describe the benefits of consuming polyunsaturated fatty acids during pregnancy and the associated factors in child development. This is an integrative bibliographic review, based on the analysis of scientific articles indexed in the MedLine, Scielo, Science Direct and Google academic databases, with a ten-year period (2010-2020). The descriptors used were: Long chain fatty polyunsaturated acid; Omega 3; Omega 6; pregnant woman and infant in Portuguese and English, with the assistance of the Boolean operator “AND”. The results of the research, after the inclusion and exclusion criteria, obtained a total of 12 articles. Studies have shown that long-chain polyunsaturated fatty acids (LCPUFA), such as those from the omega 3 and omega 6 series, especially docosahexaenoic acid and eicosapentaenoic acid, are essential for child growth and development, and have a primary role in the formation and in the functioning of the central nervous system and the retina and improves birth weight. In addition, in pregnant women it works by reducing the risk of prematurity. The LCPUFA have an anti-inflammatory and antioxidant function, reduce oxidative stress, and control depressive symptoms before and after pregnancy. However, further studies are needed to address the appropriate quantities for the gestational period favorable to the mother-child health.Keywords: Polyunsaturated fatty acid; Omega 3; Omega 6; Pregnant; Infant.ResumenEl objetivo de este estudio es describir los beneficios de consumir ácidos grasos poliinsaturados durante el embarazo y los factores asociados en el desarrollo infantil. Se trata de una revisión bibliográfica integradora, basada en el análisis de artículos científicos indexados en las bases de datos académicas MedLine, Scielo, Science Direct y Google, con un período de diez años (2010-2020). Los descriptores utilizados fueron: ácido graso poliinsaturado de cadena larga; omega 3; omega 6; embarazada y lactante, en portugués e inglés, con la ayuda del operador booleano “AND”. Los resultados de la investigación, luego de los criterios de inclusión y exclusión, obtuvieron un total de 12 artículos. Los estudios han demostrado que los ácidos grasos poliinsaturados de cadena larga (AGPICL), como los de las series omega 3 y omega 6, especialmente el ácido docosahexaenoico y el ácido eicosapentaenoico, son esenciales para el crecimiento y desarrollo infantil y tienen un papel principal en la formación y en el funcionamiento del sistema nervioso central y la retina, y mejora del peso al nacer. Además, los AGPICL actúan en mujeres embarazadas reduciendo el riesgo de prematurez, tienen una función antiinflamatoria y antioxidante, reducen el estrés oxidativo y controlan los síntomas depresivos antes y después del embarazo. Sin embargo, se necesitan más estudios para abordar las cantidades apropiadas para el período gestacional favorable a la salud de la madre y su hijo.Palabras Clave: Ácido graso poliinsaturado; Omega 3; Omega 6; Embarazada; Infante.

Reverse association of omega-3/omega-6 polyunsaturated fatty acids ratios with carotid atherosclerosis in patients on hemodialysis

2016 ◽  
Vol 249 ◽  
pp. 65-69 ◽  
Author(s):  
Norio Umemoto ◽  
Hideki Ishii ◽  
Daisuke Kamoi ◽  
Toru Aoyama ◽  
Takashi Sakakibara ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Carotid Atherosclerosis ◽  
Omega 3 ◽  
Omega 6 ◽  
3 Omega

scholarly journals Effects of Dietary n–3 and n–6 Polyunsaturated Fatty Acids in Inflammation and Cancerogenesis

2021 ◽  
Vol 22 (13) ◽  
pp. 6965
Author(s):  
Kamila P. Liput ◽  
Adam Lepczyński ◽  
Magdalena Ogłuszka ◽  
Agata Nawrocka ◽  
Ewa Poławska ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Saturated Fatty Acids ◽  
Epidemiological Studies ◽  
Omega 3 ◽  
Metabolic Disturbances ◽  
Cancer Models ◽  
Omega 6 ◽  
3 Omega

The dietary recommendation encourages reducing saturated fatty acids (SFA) in diet and replacing them with polyunsaturated fatty acids (PUFAs) n–3 (omega–3) and n–6 (omega–6) to decrease the risk of metabolic disturbances. Consequently, excessive n–6 PUFAs content and high n–6/n–3 ratio are found in Western-type diet. The importance of a dietary n–6/n–3 ratio to prevent chronic diseases is linked with anti-inflammatory functions of linolenic acid (ALA, 18:3n–3) and longer-chain n–3 PUFAs. Thus, this review provides an overview of the role of oxylipins derived from n–3 PUFAs and oxylipins formed from n–6 PUFAs on inflammation. Evidence of PUFAs’ role in carcinogenesis was also discussed. In vitro studies, animal cancer models and epidemiological studies demonstrate that these two PUFA groups have different effects on the cell growth, proliferation and progression of neoplastic lesions.

scholarly journals Circulating and Dietary Omega‐3 and Omega‐6 Polyunsaturated Fatty Acids and Incidence of CVD in the Multi‐Ethnic Study of Atherosclerosis

2013 ◽  
Vol 2 (6) ◽  
Author(s):  
Marcia C. de Oliveira Otto ◽  
Jason H. Y. Wu ◽  
Ana Baylin ◽  
Dhananjay Vaidya ◽  
Stephen S. Rich ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Omega 3 ◽  
Ethnic Study ◽  
Omega 6

scholarly journals Polyunsaturated Fatty Acids: Impact on Health and Disease Status

2021 ◽  
Vol 2 (2) ◽  
pp. 12
Author(s):  
Samina Akbar ◽  
Muhammad Zeeshan Bhatti ◽  
Rida Fatima Saeed ◽  
Asma Saleem Qazi
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Disease Status ◽  
Epidemiological Studies ◽  
Lipid Lowering ◽  
Therapeutic Effects ◽  
Omega 3 ◽  
Beneficial Effects ◽  
Omega 6 ◽  
Health And Disease

Over the last decades, the polyunsaturated fatty acids (PUFAs) have been largely explored not only for their nutritional value but also for the numerous biological functions and therapeutic effects. The serum and erythrocyte levels of PUFAs depend on the genetic control of metabolism as well as the dietary intake and are considered to reflect the health and disease status of an individual. Two families of PUFAs, omega-3 (n-3) and omega-6 (n-6), have gained much attention because of their involvement in the production of bioactive lipid mediators and therefore, a balanced omega-6/omega-3 ratio is crucial in maintaining the overall health of an individual. Omega-3 PUFAs, notably eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3) have been shown to exert beneficial effects, possibly due to their lipid-lowering, anti-inflammatory, anti-hypertensive and cardioprotective effects, whereas omega-6 fatty acids such as arachidonic acid (ARA, 20:4n-6) exhibit the opposite properties. Even though, numerous epidemiological studies and clinical interventions have clearly established the effectiveness of omega-3 PUFAs in various pathological conditions including dyslipidemia, obesity, diabetes, cancer, cardiovascular and neurodegenerative diseases, some controversies do exist about the beneficial effects of omega-3 PUFAs and need to be clarified. Larger clinical trials with extended follow-up periods are required along with a careful dose selection, in order to confirm the clinical significance and efficacy of omega-3 PUFAs as therapeutic agents.

scholarly journals Erythrocyte omega-3, omega-6 and trans fatty acids in relation to risk of preeclampsia among women delivering at harare maternity hospital, Zimbabwe

2007 ◽  
pp. 37-50
Author(s):  
K Mahomed ◽  
MA Williams ◽  
IB King ◽  
S Mudzamiri ◽  
GB Woelk
Keyword(s):  
Fatty Acids ◽  
Confidence Interval ◽  
Odds Ratio ◽  
Trans Fatty Acids ◽  
Positive Association ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Omega 6 ◽  
3 Omega ◽  
Risk Of Preeclampsia

We sought to examine the association between maternal erythrocyte omega-3, omega-6 and trans fatty acids and risk of preeclampsia. We conducted a case-control study of 170 women with proteinuric, pregnancy-induced hypertension and 185 normotensive pregnant women who delivered at Harare Maternity Hospital, Harare, Zimbabwe. We measured erythrocyte omega-3, omega-6 and trans fatty acid as the percentage of total fatty acids using gas chromatography. After multivariate adjustment for confounding factors, women in the highest quartile group for total omega-3 fatty acids compared with women in the lowest quartile experienced a 14% reduction in risk of preeclampsia (odds ratio 0.86, 95% confidence interval 0.45 to 1.63). For total omega-6 fatty acids the odds ratio was 0.46 (95% confidence interval 0.23 to 0.92), although there was suggestion of a slight increase in risk of preeclampsia associated with high levels of arachidonic acid. Among women in the highest quartile for arachidonic acid the odds ratio was 1.29 (95% confidence interval 0.66 to 2.54). A strong statistically significant positive association of diunsaturated fatty acids with a trans double bond with risk of preeclampsia was observed. Women in the upper quartile of 9-cis 12-trans octadecanoic acid (C(18:2n6ct)) compared with those in the lowest quartile experienced a 3-fold higher risk of preeclampsia (odds ratio = 3.02, 95% confidence interval 1.41 to 6.45). Among women in the highest quartile for 9-trans 12-cis octadecanoic acid (C(18:2n6tc)) the odds ratio was 3.32 (95% confidence interval 1.55 to 7.13). Monounsaturated trans fatty acids were also positively associated with the risk of preeclampsia, although of much reduced magnitude. We observed a strong positive association of trans fatty acids, particularly diunsaturated trans fatty acids, with the risk of preeclampsia. We found little support for the hypothesized inverse association between omega-3 fatty acids and preeclampsia risk in this population. Polyunsaturated fatty acids, particularly omega-3 fatty acids, were comparatively lower in Zimbabwean than among US pregnant women. Given the limited inter-person variation in omega-3 fatty acids among Zimbabwean women, our sample size may be too small to adequately assess the relation in this population.

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