scholarly journals Validation and comparison of clinical prediction rules for invasive candidiasis in intensive care unit patients: a matched case-control study

Critical Care ◽  
2011 ◽  
Vol 15 (4) ◽  
pp. R198 ◽  
Author(s):  
Elizabeth D Hermsen ◽  
Michelle K Zapapas ◽  
Melissa Maiefski ◽  
Mark E Rupp ◽  
Alison G Freifeld ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Invasive Candidiasis ◽  
Case Control Study ◽  
Case Control ◽  
Clinical Prediction ◽  
Prediction Rules ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

scholarly journals Factors Predicting Cardiac Arrest in the Intensive Care Unit: A Matched Case-Control Study

2021 ◽  
Author(s):  
Wentao Sang ◽  
Yuhui Pan ◽  
Xue Zhao ◽  
Shuo Wu ◽  
Wen Zheng ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Cardiac Arrest ◽  
Intensive Care ◽  
Case Control Study ◽  
Vital Signs ◽  
Case Control ◽  
Time Points ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

Abstract Background: Early detection and intervention of disease deterioration are the keys to reducing the incidence of preventable intensive care unit cardiac arrest (ICU-CA). We aimed to investigate the ICU-CA predictive factors, including vital signs and laboratory indicators, and to analyze the performance of trends value of those factors on predicting ICU-CA. Methods: We conducted a matched case-control study at Qilu Hospital of Shandong University. Data on adult patients in ICU who suffered a cardiac arrest (CA) were retrospectively collected from 2016 to 2019, including vital signs and laboratory indicators at 48, 36, 24, 12, and 8 hours before ICU-CA. These cases were matched (ward, sex, and admission data) with controls (no ICU-CA) at a 1:2 ratio. Univariable logistic regression was used for statistical comparisons between cases and controls, and multivariate logistic regression was used to investigate the independent associations of indicators and their tendency with ICU-CA at given time points. The area under receiver operating characteristic (AUROC) was used to evaluate the predictive performance on ICU-CA.Results: Of 6164 ICU patients, 1042 patients suffered an ICU-CA during the 3 years. After careful screening, a total of 427 patients were included as the cases in the study, and 790 patients were included as controls. The vital signs and laboratory indicators at 8h before cardiac arrest, such as heart rate (HR), respiratory rate (RR), systolic blood pressure (SBP), oxygen saturation (SaO2), hemoglobin (HGB), potassium (K+), sodium (Na+), lactic acid (Lac), and pH all can predict the ICU-CA. The mean value, maximum value, minimum value, and range of these indicators were related to the occurrence of ICU-CA, and the trend values were more accurate than the current value for the variability in laboratory indicators. Conclusions: The ability of trends value of laboratory indicators for predicting ICU-CA was more accurate than the value at given time points for the variability in laboratory indicators. Adding trends of laboratory indicators may increase the accuracy of models designed to detect critical illness in ICU. Trial registration: ClinicalTrials.gov Identifier: NCT04670458.

Risk Factors for Staphylococcus aureus Acquisition in the Neonatal Intensive Care Unit: A Matched Case-Case-Control Study

2017 ◽  
Vol 39 (1) ◽  
pp. 46-52 ◽  
Author(s):  
Matthew C. Washam ◽  
Andrea Ankrum ◽  
Beth E. Haberman ◽  
Mary Allen Staat ◽  
David B. Haslam
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Staphylococcus Aureus ◽  
Intensive Care ◽  
Neonatal Intensive Care ◽  
Case Control Study ◽  
Case Control ◽  
Entire Cohort ◽  
Matched Case ◽  
Control Study

OBJECTIVETo determine risk factors independent of length of stay (LOS) for Staphylococcus aureus acquisition in infants admitted to the neonatal intensive care unit (NICU).DESIGNRetrospective matched case–case-control study.SETTINGQuaternary-care referral NICU at a large academic children’s hospital.METHODSInfants admitted between January 2014 and March 2016 at a level IV NICU who acquired methicillin resistant (MRSA) or susceptible (MSSA) S. aureus were matched with controls by duration of exposure to determine risk factors for acquisition. A secondary post hoc analysis was performed on the entire cohort of at-risk infants for risk factors identified in the primary analysis to further quantify risk.RESULTSIn total, 1,751 infants were admitted during the study period with 199 infants identified as having S. aureus prevalent on admission. There were 246 incident S. aureus acquisitions in the remaining at-risk infant cohort. On matched analysis, infants housed in a single-bed unit were associated with a significantly decreased risk of both MRSA (P=.03) and MSSA (P=.01) acquisition compared with infants housed in multibed pods. Across the entire cohort, pooled S. aureus acquisition was significantly lower in infants housed in single-bed units (hazard ratio,=0.46; confidence interval, 0.34–0.62).CONCLUSIONSNICU bed design is significantly associated with S. aureus acquisition in hospitalized infants independent of LOS.Infect Control Hosp Epidemiol 2018;39:46–52

Do nurse navigators bring about fewer patient hospitalisations?

2019 ◽  
Vol 33 (1) ◽  
pp. 51-62 ◽  
Author(s):  
Louisa G. Gordon ◽  
Amy J. Spooner ◽  
Natasha Booth ◽  
Tai-Rae Downer ◽  
Adrienne Hudson ◽  
...  
Keyword(s):  
Intensive Care ◽  
Case Control Study ◽  
Length Of Hospital Stay ◽  
Case Control ◽  
Care Quality ◽  
Content Type ◽  
Healthcare Needs ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

Purpose Nurse navigators (NNs) coordinate patient care, improve care quality and potentially reduce healthcare resource use. The purpose of this paper is to undertake an evaluation of hospitalisation outcomes in a new NN programme in Queensland, Australia. Design/methodology/approach A matched case-control study was performed. Patients under the care of the NNs were randomly selected (n=100) and were matched to historical (n=300) and concurrent (n=300) comparison groups. The key outcomes of interest were the number and types of hospitalisations, length of hospital stay and number of intensive care unit days. Generalised linear and two-part models were used to determine significant differences in resources across groups. Findings The control and NN groups were well matched on socio-economic characteristics, however, groups differed by major disease type and number/type of comorbidities. NN patients had high healthcare needs with 53 per cent having two comorbidities. In adjusted analyses, compared with the control groups, NN patients showed higher proportions of preventable hospitalisations over 12 months, similar days in intensive care and a smaller proportion had overnight stays in hospital. However, the NN patients had significantly more hospitalisations (mean: 6.0 for NN cases, 3.4 for historical group and 3.2 for concurrent group); and emergency visits. Research limitations/implications As many factors will affect hospitalisation rates beyond whether patients receive NN care, further research and longer follow-up is required. Originality/value A matched case-control study provides a reasonable but insufficient design to compare the NN and non-NN exposed patient outcomes.

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