Bioavailability and metabolic effects in humans of n-3 polyunsaturated fatty acids and conjugated linoleic acid after consumption of naturally enriched cow milk

2012 ◽  
Author(s):  
Emilio Ros
Keyword(s):  
Fatty Acids ◽  
Linoleic Acid ◽  
Polyunsaturated Fatty Acids ◽  
Conjugated Linoleic Acid ◽  
Metabolic Effects ◽  
Cow Milk

Changes in delayed type hypersensitivity, egg antibody content and immune cell fatty acid composition of layer birds fed conjugated linoleic acid, n-6 or n-3 fatty acids

2004 ◽  
Vol 84 (2) ◽  
pp. 221-228 ◽  
Author(s):  
R. K. Selvaraj ◽  
G. Cherian
Keyword(s):  
Fatty Acids ◽  
Immune Response ◽  
Fatty Acid ◽  
Linoleic Acid ◽  
Polyunsaturated Fatty Acids ◽  
Conjugated Linoleic Acid ◽  
Oxidation Products ◽  
Thigh Muscle ◽  
Delayed Type Hypersensitivity ◽  
Lipid Oxidation Products

The effects of polyunsaturated fatty acids on delayed type hypersensitivity (DTH), egg yolk antibody content, immune tissue fatty acid profile and lipid oxidation products of layer birds were investigated. One hundred and twenty layer birds were fed diets containing conjugated linoleic acid (CLA) + animal fat (Diet I), sunflower oil (Diet II), canola + flax oil (Diet III) or fish oil (Diet IV). The total added lipid content of the diet was 3%. Birds fed Diets III and IV had higher content of n-3 fatty acids in lymphocyte and splenocytes. Thiobarbituric reactive substances were higher (P < 0.05) in the breast and thigh muscle of Diet IV fed birds. Serum and yolk anti-BSA antibody contents were higher (P < 0.05) in birds fed Diets III and IV. DTH was decreased (P < 0.05) in birds fed Diets IV and III. The number of lymphocyte CD4+ and CD8+ cells and spleen mononuclear cell CD4+, CD8+ and IgM+ cells did not differ (P > 0.05) between treatment groups. Feeding n-3 fatty acids increased antibody-mediated immune response, while n-6 fatty acids and CLA increased cell-mediated immune response. Key words: Conjugated linoleic acid, polyunsaturated fatty acids, delayed type hypersensitivity, immunoglobulins

Effects of Enrichment with Polyunsaturated Fatty Acids (Omega-3 and Conjugated Linoleic Acid) on Consumer Liking of Beef Aged for 7 or 21 d Evaluated at Different Locations

2014 ◽  
Vol 79 (11) ◽  
pp. S2377-S2382 ◽  
Author(s):  
María Pérez-Juan ◽  
Carolina E. Realini ◽  
Marta Barahona ◽  
Maria Victoria Sarriés ◽  
Maria del Mar Campo ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Linoleic Acid ◽  
Polyunsaturated Fatty Acids ◽  
Conjugated Linoleic Acid ◽  
Omega 3

scholarly journals Conjugated Linoleic Acid: A Functional Food?

2003 ◽  
Vol 16 (3) ◽  
pp. 215-220 ◽  
Author(s):  
N. D'Orazio ◽  
C. Ficoneri ◽  
G. Riccioni ◽  
P. Conti ◽  
T.C. Theoharides ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Milk Fat ◽  
Functional Food ◽  
Well Being ◽  
Metabolic Effects ◽  
Cow Milk ◽  
Dry Fractionation ◽  
Obesity And Diabetes ◽  
Fatty Acids Metabolism

Scientific interest in conjugated linoleic acid (CLA) started in 1987 when Michael Pariza's team of Wisconsin University observed its inhibitory effects on chemically induced skin tumors in mice. Numerous studies have since examined CLA's role in cancer, immune function, oxidative stress, atherosclerosis, lipid and fatty acids metabolism, bone formation and composition, obesity, and diabetes. Still it's not clear yet either through which mechanisms CLA produces its numerous metabolic effects. We now know that CLA contents in cow milk fat can be enriched through dry fractionation, but this knowledge doesn't allow sufficient certainty to qualify this nutrient, as a functional food, capable of increasing well being and reducing the risk of disease.

scholarly journals The effect of polyunsaturated fatty acids, including conjugated linoleic acid, on calcium absorption and bone metabolism and composition in young growing rats

2003 ◽  
Vol 90 (4) ◽  
pp. 743-750 ◽  
Author(s):  
Owen Kelly ◽  
Siobhan Cusack ◽  
Christopher Jewell ◽  
Kevin D. Cashman
Keyword(s):  
Fatty Acids ◽  
Linoleic Acid ◽  
Polyunsaturated Fatty Acids ◽  
Conjugated Linoleic Acid ◽  
Bone Metabolism ◽  
Calcium Absorption ◽  
Ex Vivo ◽  
Prostaglandin E ◽  
Mrna Levels ◽  
Growing Rats

The effect of polyunsaturated fatty acids (PUFA), in particular conjugated linoleic acid (CLA), on Ca and bone metabolism is unclear. In a 2 × 2 factorial design study, forty male 4-week-old rats were fed a control diet containing 70 g added fat (soyabean oil (SBO;n–6 PUFA-rich diet) or menhaden oil–safflower oil (MSO;n−3 PUFA-rich diet))/kg diet with 0 or 10 g CLA/kg for 8 weeks.Ex vivoprostaglandin E2biosynthesis by bone organ culture was significantly higher (P<0·001) in rats consuming SBO compared with MSO, irrespective of CLA. Addition of the CLA treatment to either diet further lowered (P<0·05)ex vivoprostaglandin E2production. Neither PUFA type nor CLA altered circulating or femoral mRNA levels of osteocalcin (a marker of bone formation) or insulin-like growth factor-I (a mediator of bone metabolism). While urinary pyridinium crosslinks levels (markers of bone resorption) were unaffected by CLA irrespective of PUFA type, they were significantly higher (P<0·05) in rats consuming SBO compared with MSO irrespective of CLA. Net fractional (%) and absolute (mg) Ca absorption were significantly (P<0·01 andP<0·05 respectively) higher in CLA-supplemented than unsupplemented animals fed on then−3 PUFA-rich diet, whereas CLA had no effect in animals fed then–6 PUFA-rich diet. There was no effect of CLA supplementation on bone mineral mass. In conclusion, CLA supplementation over 8 weeks appeared to enhance Ca absorption in young growing rats fed ann−3 PUFA-rich diet, but had no measurable effect on bone metabolism or bone mass over this time frame.

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