scholarly journals Flatness of the Meckel cave may cause primary trigeminal neuralgia: a radiomics-based study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Jinzhi Lin ◽  
Yong Zhang ◽  
Wuming Li ◽  
Jianhao Yan ◽  
Yiquan Ke
Keyword(s):  
Trigeminal Neuralgia ◽  
Morphological Characteristics ◽  
Healthy Controls ◽  
Unaffected Side ◽  
3D Slicer ◽  
Affected Side ◽  
Left And Right ◽  
The Right ◽  
Primary Trigeminal Neuralgia ◽  
3.0T Mri

Abstract Background Neurovascular contact (NVC) is the main cause of primary trigeminal neuralgia (PTN); however, cases of PTN without NVC are still observed. In this study, the Meckel cave (MC) morphology in PTN were analyzed by radiomics and compared to healthy controls (HCs) to explore the cause of PTN. Methods We studied the 3.0T MRI data of 115 patients with PTN and 46 HCs. Bilateral MC was modeled using the 3D Slicer software, and the morphological characteristics of MC were analyzed using the radiomics method. Results The right side incidence rate in the PTN group was higher than the left side incidence. By analyzing the flatness feature of MC, we observed that the affected side of the PTN was lower than that of the unaffected side, the right MC of the PTN and HC was lower than that of the left MC, the MC of the affected side of the left and right PTN without bilateral NVC was lower than that of the unaffected side. Conclusions By providing a method to analyze the morphology of the MC, we found that there is an asymmetry in the morphology of bilateral MC in the PTN and HC groups. It can be inferred that the flatness of the MC may be a cause of PTN.

scholarly journals Flatness of the Meckel Cave May Cause Primary Trigeminal Neuralgia: a Radiomics-based Study

2021 ◽  
Author(s):  
Jinzhi Lin ◽  
Yong Zhang ◽  
Wuming Li ◽  
Jianhao Yan ◽  
Yiquan Ke
Keyword(s):  
Trigeminal Neuralgia ◽  
Incidence Rate ◽  
Morphological Characteristics ◽  
Healthy Controls ◽  
Unaffected Side ◽  
Affected Side ◽  
Left And Right ◽  
The Right ◽  
Primary Trigeminal Neuralgia ◽  
3.0T Mri

Abstract Background: Neurovascular contact (NVC) is the main cause of primary trigeminal neuralgia (PTN); however, cases of PTN without NVC are still observed. In this study, the Meckel cave (MC) morphology in PTN were analyzed by radiomics and compared to healthy controls (HCs) to explore the cause of PTN.Methods: We studied the 3.0T MRI data of 115 patients with PTN and 46 HCs. Bilateral MC was modeled using the 3Dslicer software, and the morphological characteristics of MC were analyzed using the radiomics method.Results: The right side incidence rate in the PTN group was higher than the left side incidence. By analyzing the flatness feature of MC, we observed that the affected side of the PTN was lower than that of the unaffected side, the right MC of the PTN and HC was lower than that of the left MC, the MC of the affected side of the left and right PTN without bilateral NVC was lower than that of the unaffected side.Conclusions: By providing a method to analyze the morphology of MC, we found that there is asymmetry in the morphology of bilateral MC in the PTN and HC groups. It can be inferred that the flatness of MC may be a cause of PTN.

Altered brain network centrality in patients with trigeminal neuralgia: a resting-state fMRI study

2019 ◽  
Vol 61 (1) ◽  
pp. 67-75 ◽  
Author(s):  
Pei-Wen Zhu ◽  
You Chen ◽  
Ying-Xin Gong ◽  
Nan Jiang ◽  
Wen-Feng Liu ◽  
...  
Keyword(s):  
Trigeminal Neuralgia ◽  
Brain Activity ◽  
Characteristic Curve ◽  
Brain Regions ◽  
Brain Network ◽  
Network Activity ◽  
Degree Centrality ◽  
Healthy Controls ◽  
Postcentral Gyrus ◽  
The Right

Background Neuroimaging studies revealed that trigeminal neuralgia was related to alternations in brain anatomical function and regional function. However, the functional characteristics of network organization in the whole brain is unknown. Purpose The aim of the present study was to analyze potential functional network brain-activity changes and their relationships with clinical features in patients with trigeminal neuralgia via the voxel-wise degree centrality method. Material and Methods This study involved a total of 28 trigeminal neuralgia patients (12 men, 16 women) and 28 healthy controls matched in sex, age, and education. Spontaneous brain activity was evaluated by degree centrality. Correlation analysis was used to examine the correlations between behavioral performance and average degree centrality values in several brain regions. Results Compared with healthy controls, trigeminal neuralgia patients had significantly higher degree centrality values in the right lingual gyrus, right postcentral gyrus, left paracentral lobule, and bilateral inferior cerebellum. Receiver operative characteristic curve analysis of each brain region confirmed excellent accuracy of the areas under the curve. There was a positive correlation between the mean degree centrality value of the right postcentral gyrus and VAS score (r = 0.885, P < 0.001). Conclusions Trigeminal neuralgia causes abnormal brain network activity in multiple brain regions, which may be related to underlying disease mechanisms.

scholarly journals Lateralized deficits in arousal processing after insula lesions: behavioral and autonomic evidence

2021 ◽  
Author(s):  
Olga Holtmann ◽  
Marcel Franz ◽  
Constanze Moenig ◽  
Jan-Gerd Tenberge ◽  
Insa Schlossmacher ◽  
...  
Keyword(s):  
Emotion Processing ◽  
Complex Structure ◽  
Large Body ◽  
Insular Cortex ◽  
Affective Processing ◽  
Healthy Controls ◽  
Left And Right ◽  
Emotional Deficits ◽  
Valence And Arousal ◽  
The Right

A large body of evidence ascribes a pivotal role in emotion processing to the insular cortex. However, the complex structure and lateralization of emotional deficits following insular damage are not understood. Here, we investigated emotional ratings of valence and arousal and skin conductance responses (SCR) to a graded series of emotionally arousing scenes in patients with left (n = 10) or right (n = 9) insular damage and in healthy controls (n = 18). We found a significant reduction in overall SCRs, arousal ratings and valence extremity scores in right-lesioned patients, as compared to left-lesioned patients and healthy controls. Additional analyses of correlations between subjective arousal ratings resp. SCR and normative arousal ratings revealed that both lesion groups had evaluative and physiological difficulties to discover changes in stimulus arousal. Although no group differences emerged on overall ratings of valence, analysis of correlations between subjective and normative valence ratings displayed markedly reduced accuracy in right-lesioned patients, as compared to left-lesioned patients and healthy controls. Our findings support the hypothesis that the left and right insulae subserve different functions in emotion processing, potentially due to asymmetrical representations of autonomic information in the left and right human forebrain. The right insula may serve as integral node for sympathetic arousal and cognitive affective processing.

Nerve atrophy and a small cerebellopontine angle cistern in patients with trigeminal neuralgia

2009 ◽  
Vol 110 (4) ◽  
pp. 633-637 ◽  
Author(s):  
Seong-Hyun Park ◽  
Sung-Kyoo Hwang ◽  
Sun-Ho Lee ◽  
Jaechan Park ◽  
Jeong-Hyun Hwang ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Trigeminal Neuralgia ◽  
Trigeminal Nerve ◽  
Cerebellopontine Angle ◽  
Cross Sectional Area ◽  
Sectional Area ◽  
Unaffected Side ◽  
Cross Sectional ◽  
Affected Side ◽  
The Mean

Object The aim of this study was to provide information to help confirm the diagnosis of trigeminal neuralgia (TN) using MR imaging. Methods The authors evaluated atrophy of the trigeminal nerve, the cross-sectional area of the cerebellopontine angle (CPA) cistern, and the length of the cisternal segment of the trigeminal nerve on the affected side in 26 consecutive patients with TN who were treated using Gamma Knife surgery. Results The mean volume of the trigeminal nerve on the affected side was significantly smaller than the mean volume of the trigeminal nerve on the unaffected side (p < 0.001). Nerve atrophy was present in 25 patients (96.2%) on the affected side and in 1 patient on the unaffected side. The mean cross-sectional area of the CPA cistern on the affected side (188.5 mm2) was significantly smaller than the mean volume on the unaffected side (232.8 mm2) in 25 of the 26 patients (p = 0.001). The mean length of the cisternal segment of the trigeminal nerve on the affected side (7.9 mm) was significantly shorter than the mean length on the unaffected side (9.6 mm) in 25 of the 26 patients (p = 0.001). Conclusions Among the patients with TN, there was a statistically significant difference in the MR imaging findings of the affected side compared with the unaffected side of the trigeminal nerve. Atrophy of the trigeminal nerve and a small CPA cistern in patients with TN provides additional markers for the diagnosis of TN and helps confirm the diagnosis based on clinical examination.

scholarly journals Plicae Palmatae on MR in Uterus Didelphys: the Incidence and Morphological Characteristics

2021 ◽  
Vol 2 (6) ◽  
pp. 01-03
Author(s):  
Wang Xiaoying
Keyword(s):  
Three Dimensional ◽  
Morphological Characteristics ◽  
Reproductive Age ◽  
Mr Images ◽  
Uterus Didelphys ◽  
Significant Difference ◽  
Cervical Disease ◽  
Left And Right ◽  
The Right ◽  
Plicae Palmatae

Objective: To investigate the incidence of plicae palmatae in uterus didelphys and its morphological characteristics on MR imaging. Methods: We retrospectively collected 37 consecutive female pelvic MR images diagnosed with uterus didelphys between August 2012 and November 2020. Patients with the following conditions were excluded: (a) repeated examination; (b) poor image quality; (c) cervical disease. Axial and coronal T2-weight images and axial three-dimensional (3D) volumetric isotropic T2-weighted acquisition (VISTA) were used to evaluate the ridge of plicae palmatae (RPP). A multiplanar reformation of the cervical axis from 3D-VISTA sequence was performed to measure the height and width of RPP. Non-normal variables based on the Kruskal-Wallis H test was used for statistical analysis. A two-tailed test where P < 0.05 was considered statistically significant. Results: Twenty-six cases were finally included in the statistics. The average age was 25.7±9.0 years (range, 10-45 years). RPP was observed on both cervices in 16 patients (61.5%), only on the left cervix in 3 patients (11.5%), and only on the right cervix in 4 patients (15.4%). There were 3 cases with no RPP observed in any of their cervix (11.5%).All RPP appear symmetrically on the anterior and posterior walls of the cervix. There was no statistically significant difference in height, width, and height/width of the RPP in the left and right cervix (p＞0.05). Conclusions: RPP is encountered in 88.5% patients with duplicated uterine cervices in our cohort. This incidence is similar to that reported in women with normal uterus of reproductive age.

scholarly journals The Morphology of Patella changed significantly after Soft Tissue Correction for children with Recurrent Patella Dislocation

2020 ◽  
Author(s):  
Jinghui Niu ◽  
Qi Qi ◽  
Kuo Hao ◽  
Wei Lin ◽  
Kang Piao ◽  
...  
Keyword(s):  
Patellar Dislocation ◽  
Morphological Characteristics ◽  
Recurrent Dislocation ◽  
Patella Dislocation ◽  
Transverse Diameter ◽  
Unaffected Side ◽  
Femoral Trochlea ◽  
Affected Side ◽  
Wiberg Index

Abstract Background: Although morphological improvement of femoral trochlea has been investigated in children with patellar dislocation after surgery, whether the patellar shape changed under the same condition is still unknown. The purpose of the study was to investigate the changes of patella morphology in transverse plane following surgical correction of recurrent patella dislocation in children.Methods: A total of 22 patients with a mean age of 9.9 years (7 to 12) were included. All had unilateral recurrent patella dislocation. The knees with recurrent patellar dislocation were treated with medial patellar retinaculum plasty and defined as the affected side. The contralateral knees with no symptom of patellar instability were considered as the unaffected side. All patients were treated between October 2014 and August 2018. Axial CT (Computed Tomography) scans were undertaken in all patients to assess the patella morphological characteristics on a particular axial image preoperatively and at the final follow-up.Results: There were not significant differences about patellar transverse diameter, thickness and Wiberg angle between affected side and unaffected side before surgery and at the last follow-up respectively ( The mean follow-up period: 28.0 ± 3.3 months). However, before surgery, the Wiberg-index in the affected side (0.74 ± 0.06) was significantly different from that in the unaffected side (0.64 ± 0.04). At the last follow-up, the Wiberg-index in the affected side (0.67 ± 0.05) and the unaffected side (0.65 ± 0.04) were not significantly different. Also, in the affected side, the Wiberg-index at the last follow-up was significantly lower than that before surgery (P < 0.05). The Wiberg-index in the unaffected side was not significantly different before surgery and at the last follow-up. Conclusion: The patella morphology can change significantly after surgical procedures in children with patellar recurrent dislocation whose epiphysis is not closed.

Dentoalveolar Growth Inhibition Induced by Bone Denudation on Palates: A Study of Two Isolated Cleft Palates with Asymmetric Scar Tissue Distribution

1999 ◽  
Vol 36 (5) ◽  
pp. 450-456 ◽  
Author(s):  
Hiroyuki Ishikawa ◽  
Hiroshi Iwasaki ◽  
Haruka Tsukada ◽  
Soowon Chu ◽  
Shinji Nakamura ◽  
...  
Keyword(s):  
Laser Doppler Flowmetry ◽  
Scar Tissue ◽  
Laser Doppler ◽  
Asymmetric Distribution ◽  
Unaffected Side ◽  
Measuring Device ◽  
Doppler Flowmetry ◽  
Affected Side ◽  
Deciduous Molar ◽  
The Right

Objective: This report presents two cases of isolated cleft palate with asymmetric distribution of postsurgical scar tissue determined by laser Doppler flowmetry. To determine the effect of mucoperiosteal denudation of the bone on maxillary alveolar growth, the analysis of dentoalveolar structures compared the affected side to the unaffected side of each case. Method: Two Japanese girls with isolated cleft palates were examined. Both subjects had undergone pushback operations (a modified version of the procedure of Wardill) for palatal repair at 18 months of age. Palatal blood flow was examined by laser Doppler flowmetry when the girls were 12 years old to determine the extent of postsurgical scar tissue over the denuded bone. To analyze the maxillary dentoalveolar structures three dimensionally, the whole surface of the upper dental cast was measured and recorded by an optical measuring device when the girls were 7 years old. Results and Conclusions: Analysis via flowmetry showed that the palatal scar tissue area was limited to the anterior tooth region on the right (unaffected) side but extended posteriorly to the premolar region on the left (affected) side in both subjects. The two girls had similar dentoalveolar structures, with the dental and alveolar arches deflected lingually at the deciduous molar area on the affected side. There were no differences in the buccolingual inclination of deciduous molars or in the vertical growth of the alveolar processes between the affected and unaffected sides. In both girls, bone denudation in the premolar region appeared to result in less than 3 mm of displacement of the teeth palatally, with no change in lingual inclination. Any effects of scar tissue on the vertical development of the alveolus were not substantiated.

scholarly journals The Infrared Radiation Temperature Characteristic of Acupoints of Mammary Gland Hyperplasia Patients

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Juanjuan Zheng ◽  
Yi Zhao ◽  
Yafang Wang ◽  
Shengfang Hu ◽  
Ping Lu ◽  
...  
Keyword(s):  
Infrared Radiation ◽  
Temperature Characteristic ◽  
Mammary Glands ◽  
Radiation Temperature ◽  
Thermal Imager ◽  
Healthy Controls ◽  
Significant Difference ◽  
Left And Right ◽  
The Right ◽  
Infrared Thermal Imager

Objective. To ascertain pathological information on hyperplasia of mammary glands (HMG) of patients via the infrared radiation temperature of acupoints.Method. Patients with HMG and healthy controls were tested using an infrared thermal imager.Results. In controls, no significant difference in temperature was observed between points with the same name (P>0.05). The temperature of all tested points was found to be higher in the group with HMG than in that of the healthy controls, except for the left and right Zusanli (ST36). The temperature of the right Rugen (ST18), Guanyuan (CV4), Qihai (CV6), and Hegu (LI4) reached a statistically significant heightened level (P=0.046~P<0.001). The temperature of the Zusanli (ST36) and Hegu (LI4) present on the right side was significantly higher than that of the left (P=0.001andP=0.004, resp.), while the temperature of the left Youmen (KI21) was significantly higher than that of the right (P=0.008).Conclusion. The temperature of the bilateral acupoints in healthy controls was symmetrical, and the raised temperatures observed of the Rugen (ST18), Guanyuan (CV4), Qihai (CV6), and Hegu (LI4) acupoints of HMG patients and the imbalance of the temperature of the bilateral acupoints Zusanli (ST36), Youmen (KI21), and Hegu (LI4) carried special pathological information about HMG disease.

scholarly journals Neuroanatomical Correlates of Macrolinguistic Aspects in Narrative Discourse in Unilateral Left and Right Hemisphere Stroke: A Voxel-Based Morphometry Study

2021 ◽  
pp. 1-16
Author(s):  
Fernanda Schneider ◽  
Karine Marcotte ◽  
Amelie Brisebois ◽  
Sabrine Amaral Martins Townsend ◽  
Anderson Dick Smidarle ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Right Hemisphere ◽  
Superior Temporal Gyrus ◽  
Matter Density ◽  
Narrative Discourse ◽  
Healthy Controls ◽  
Voxel Based Morphometry ◽  
Gray Matter Density ◽  
Left And Right ◽  
The Right

Background A growing body of literature has demonstrated the importance of discourse assessment in patients who suffered from brain injury, both in the left and right hemispheres, as discourse represents a key component of functional communication. However, little is known about the relationship between gray matter density and macrolinguistic processing. Purpose This study aimed to investigate this relationship in a group of participants with middle–low to low socioeconomic status. Method Twenty adults with unilateral left hemisphere ( n = 10) or right hemisphere ( n = 10) chronic ischemic stroke and 10 matched (age, education, and socioeconomic status) healthy controls produced three oral narratives based on sequential scenes. Voxel-based morphometry analysis was conducted using structural magnetic resonance imaging. Results Compared to healthy controls, the left hemisphere group showed cohesion impairments, whereas the right hemisphere group showed impairments in coherence and in producing macropropositions. Cohesion positively correlated with gray matter density in the right primary sensory area (PSA)/precentral gyrus and the pars opercularis. Coherence, narrativity, and index of lexical informativeness were positively associated with the left PSA/insula and the superior temporal gyrus. Macropropositions were mostly related to the left PSA/insula and superior temporal gyrus, left cingulate, and right primary motor area/insula. Discussion Overall, the present results suggest that both hemispheres are implicated in macrolinguistic processes in narrative discourse. Further studies including larger samples and with various socioeconomic status should be conducted. Supplemental Material https://doi.org/10.23641/asha.14347550

scholarly journals Anatomic Variations of Mandibular Condyles in Brazilian Specimens

2018 ◽  
Vol 35 (03) ◽  
pp. 194-197
Author(s):  
Roberta Fonseca ◽  
Luana Schetino ◽  
Janice da Silva ◽  
Camila Almeida-Leite
Keyword(s):  
Image Acquisition ◽  
Morphological Characteristics ◽  
Anatomical Landmarks ◽  
Anatomic Variations ◽  
Rigid Support ◽  
Extensive Surface ◽  
Left And Right ◽  
The Right

Objective To describe the morphological characteristics and asymmetries between the left and right mandibular condyles in Brazilian cadaveric specimens. Material and Methods Thirty-two jaws were placed on a rigid support for image acquisition of the frontal and lateral views. The shapes of the mandibular condyles were classified, and measurements of the distance between the anatomical landmarks in the lateral and frontal views were performed. Results Mandibular length and width were not different between the right and left sides. Regarding the shapes of the mandibular condyles, the rounded type was the most frequent, followed by marked medial slope; flattened; overhanging lateral and medial slopes; downward flattening of both slopes and their merger in a single, extensive surface; and deformity and marked lateral slope with flaring and flattening. Asymmetry between the left and right mandibular condyles was present in 40% of the specimens. Conclusion The anatomy of mandibular condyles varies greatly, and this knowledge can avoid misdiagnosis by image examination of the anatomic variations.

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