Adult pancreatic cavernous hemangioma: case presentation of a benign tumor with a complex composition

Abstract Background Pancreatic cavernous hemangioma is an extremely rare benign tumor that is difficult to diagnose on an imaging examination, and its histopathological examination has rarely been reported. Case presentation Herein, we present the case of a 63-year-old man who was admitted to the hospital due to left upper abdominal pain and defecation unformed for more than 2 years. None of the positive results obtained from the physical examination could explain his symptoms. The imaging examination indicated a multilocular cyst with septa in the head of the pancreas. The patient underwent a pancreaticoduodenectomy, and the pathologic diagnosis was pancreatic cavernous hemangioma. The histopathological examination showed that the lesion was positive for benign vascular markers, such as CD31, CD34 and F8, and negative for lymphocyte markers, such as D2–40. Moreover, it was also positive for ERG and cytokeratin markers, CAM5.2 and AE1/AE3, indicating the complexity of its components, and Ki-67 negativity revealed its benign nature. Conclusions Pancreatic cavernous hemangioma has a complex composition that may be reflected not only in the imaging examination but also in the immunohistochemical detection, and it may achieve a good outcome by surgical excision.

Download Full-text

Nodular fasciitis on the zygomatic region: a rare presentation

Anais Brasileiros de Dermatologia ◽

10.1590/abd1806-4841.20132474 ◽

2013 ◽

Vol 88 (6 suppl 1) ◽

pp. 89-92 ◽

Cited By ~ 3

Author(s):

Ilner de Souza e Souza ◽

Mayra Carriijo Rochael ◽

Rogério Estevam Farias ◽

Roberto Bezerra Vieira ◽

Janaina Silva Tirapelle Vieira ◽

...

Keyword(s):

Benign Tumor ◽

Histopathological Examination ◽

Excisional Biopsy ◽

Nodular Fasciitis ◽

Rare Presentation ◽

Ki 67 ◽

Immunohistochemical Markers ◽

The Face ◽

Rare Location ◽

High Cellularity

Nodular fasciitis is a benign tumor, resulting from reactive proliferation composed of fibroblastic/myofibroblastic cells. Due to its rapid growth and high cellularity it may be mistaken for sarcoma. Despite the possibility of spontaneous regression, excision is the treatment of choice. A 24-year-old female patient presented with a nodule on the zygomatic region with 3 months of evolution. Excisional biopsy was performed. Histopathological examination associated with immunohistochemical markers HHF35, AML and Ki-67 allowed diagnostic confirmation. The main relevance of the case presented is its rare location, suggesting its inclusion among the differential diagnoses of tumor lesions on the face.

Download Full-text

Primary epithelioid rhabdomyosarcoma of the stomach: a case report and review of literature

Diagnostic Pathology ◽

10.1186/s13000-019-0917-y ◽

2019 ◽

Vol 14 (1) ◽

Author(s):

Yangkun Wang ◽

Pei Guo ◽

Zhishang Zhang ◽

Runde Jiang ◽

Zuguo Li

Keyword(s):

Tumor Cells ◽

Unusual Case ◽

Histopathological Examination ◽

Gastroesophageal Junction ◽

Rare Tumor ◽

Review Of Literature ◽

Ki 67 ◽

Case Presentation ◽

Cytoplasmic Content ◽

Mitotic Figures

Abstract Background Epithelioid rhabdomyosarcoma is a rare tumor that generally occurs in the bladder, the parotid gland, or the skin of the neck. We describe an unusual case of primary epithelioid rhabdomyosarcoma of the stomach and review the literature. Case presentation A 64-year-old woman presented with a lesion at the gastroesophageal junction. Histopathological examination showed irregularly sized round cells with low cytoplasmic content and eccentric nuclei. Mitotic figures were present. Fibrovascular septa and areas of necrosis were observed between tumor cells. Tumor cells were strongly positive for MyoD1, desmin, and myogenin, and weakly positive for actin, CD56, and PGP9.5. The ki-67 index was ≥90%. Conclusions Primary epithelioid rhabdomyosarcoma of the stomach is extremely rare. Better awareness of this entity is necessary for early diagnosis and treatment.

Download Full-text

Ovarian Hemangioma: a rare entity

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20182023 ◽

2018 ◽

Vol 7 (6) ◽

pp. 2490

Author(s):

Mona Dahal ◽

Paricha Upadhyaya ◽

Purbesh Adhikari ◽

Diksha Karki ◽

Niraj Regmi

Keyword(s):

Abdominal Pain ◽

Cavernous Hemangioma ◽

Cystic Lesion ◽

Radical Surgery ◽

Histopathological Examination ◽

Correct Diagnosis ◽

Lower Abdominal Pain ◽

Surgical Excision ◽

Vascular Tumors ◽

Rare Entity

Ovarian hemangiomas are uncommon benign vascular tumors of ovary. Most of them are asymptomatic and detected incidentally during surgery. Authors report a case of 41 years female, parity 2; with complain of lower abdominal pain for 6 months. Ultrasonography showed a cystic lesion at right adnexa with a heterogeneously echogenic component within and devoid of internal vascularity. Laparoscopic right adnexal cystectomy was done, which on histopathological examination demonstrated features of cavernous hemangioma replacing the ovarian parenchyma. As surgical excision is treatment of choice, correct diagnosis is essential to avoid unnecessary radical surgery and treatment.

Download Full-text

Lymphangiofibrolipomatous hamartomaous polyp of tonsil

BMJ Case Reports ◽

10.1136/bcr-2019-230030 ◽

2019 ◽

Vol 12 (8) ◽

pp. e230030

Author(s):

Sejal Mehta ◽

Shilpy Jha ◽

Amit Kumar Adhya ◽

Suvradeep Mitra

Keyword(s):

Foreign Body ◽

Benign Tumor ◽

Histopathological Examination ◽

Surgical Excision ◽

Disease Recurrence ◽

Foreign Body Sensation ◽

Normal Tissues ◽

Complete Surgical Excision ◽

Body Sensation ◽

Benign Tumours

Benign tumours of the tonsils are rare. Majority of these lesions are diagnosed as squamous papilloma. Hamartoma is a benign tumor-like malformation. Hamartoma in tonsils is unique and only a few anecdotal cases are reported until now. Tonsillar hamartoma usually presents as unilateral or bilateral polyp with clinical features of dysphagia or foreign body sensation. Histopathologically, normal tissues are noted in a haphazard or disorganised way. We hereby present a case of 31-year-old male patient with tonsillar hamartomatous polyp presenting with the symptom of a foreign body sensation in the throat. The diagnosis of this entity and its distinction from other clinico-pathological mimickers require histopathological examination and awareness. A complete surgical excision is curative without any evidence of disease recurrence.

Download Full-text

TRICHILEMMAL CYST OF THE THIRD FINGERTIP: A CASE REPORT

Hand Surgery ◽

10.1142/s0218810414720113 ◽

2014 ◽

Vol 19 (01) ◽

pp. 131-133 ◽

Cited By ~ 3

Author(s):

Cenk Melikoglu ◽

Fikret Eren ◽

Barış Keklik ◽

Cem Aslan ◽

Mustafa Sutcu ◽

...

Keyword(s):

Case Report ◽

Histopathological Examination ◽

Surgical Excision ◽

Skin Lesions ◽

Hair Follicles ◽

Nodular Lesion ◽

Case Presentation ◽

The Third ◽

Trichilemmal Cyst ◽

Common Skin

Introduction: Trichilemmal cysts (TCs) are common skin lesions that occur in hairy areas. A TC involving a fingertip has not been previously described in the literature. We herein report a case of a TC occupying a fingertip region. Case presentation: A 43-year-old woman presented with a 1.5 × 1.5 cm nodular lesion on the third fingertip. The lesion was completely excised, and histopathological examination revealed a TC. Conclusion: TCs may involve atypical locations, such as fingertips, where there are no hair follicles. After surgical excision, a careful histopathological examination should be performed to differentiate TCs from proliferating pilar tumors.

Download Full-text

Intramuscular Cavernous Hemangioma of Medial Rectus Muscle in Paediatric Age Group

Case Reports in Ophthalmological Medicine ◽

10.1155/2017/1076404 ◽

2017 ◽

Vol 2017 ◽

pp. 1-3

Author(s):

Anuj Mehta ◽

Shalini Butola ◽

Mayuresh Naik ◽

Sangeeta Abrol ◽

Anju Kumari

Keyword(s):

Cavernous Hemangioma ◽

Histopathological Examination ◽

Rectus Muscle ◽

Surgical Excision ◽

Medial Rectus ◽

Paediatric Age ◽

Size Firm ◽

Minimal Contrast ◽

The Right ◽

Local Examination

An 11-year-old male child presented with a mass on the nasal aspect of the right eye that has been there for the last 2 years. Extraocular movements were decreased in the right eye on levoversion, levoelevation, and levodepression. Local examination revealed a bluish mass with irregular surface and ill-defined margins located in the medial rectus muscle. The mass was 10 × 20 mm in size, firm, nodular, nontender, nonpulsatile, noncompressible, and nonreducible. MRI of the orbit revealed a well-defined mass of approximately 23 × 13 mm along the medial rectus (MR) muscle. It was hyperintense on T2W images with very minimal contrast enhancement. A provisional diagnosis of hemangioma or lymphangioma with intralesional haemorrhage was made. During surgical excision, the mass was found to be encapsulated by MR fibres. The MR fibres were separated, and the mass measuring 20 × 8 × 6.5 mm was removed and sent for histopathology. The histopathological examination revealed an intramuscular cavernous hemangioma.

Download Full-text

Neuroendocrine tumor arising from the greater omentum treated with laparoscopic tumor resection: a case report

Surgical Case Reports ◽

10.1186/s40792-021-01217-4 ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Taichi Terai ◽

Kenji Nakagawa ◽

Kota Nakamura ◽

Shunsuke Doi ◽

Kohei Morita ◽

...

Keyword(s):

Neuroendocrine Tumor ◽

Histopathological Examination ◽

Tumor Resection ◽

Ventral Side ◽

Greater Omentum ◽

Preoperative Imaging ◽

Ki 67 ◽

Case Presentation ◽

First Case ◽

Omental Tumor

Abstract Background Primary omental tumors are extremely rare. Herein, we report the first case of a primary omental neuroendocrine tumor (NET). Case presentation A 59-year-old woman was referred to our hospital for the treatment of an 18-mm tumor located at the ventral side of the duodenum. No other tumor was detected. The preoperative imaging diagnosis was omental tumor. A laparoscopic tumor resection was performed. Histopathological examination revealed that the tumor consisted of cuboidal cells with eosinophilic, granular cytoplasm showing trabecular or ribbon architecture. No other component was seen. The mitotic count was of 5 per 10 high-power fields. Immunohistochemical staining was positive for chromogranin A, synaptophysin, and CD56. Her Ki-67 index was 5%. These results led to the diagnosis of grade 2 omental NET. The patient was discharged on the 3rd postoperative day without any complications and did not develop any recurrence for 3 years. Conclusions We encountered a very rare case of omental NET. Complete resection is recommended with minimally invasive surgery for the diagnosis of NET.

Download Full-text

Congenital orbital teratoma: A case report

Journal of Neonatal Surgery ◽

10.47338/jns.v9.523 ◽

2020 ◽

Vol 9 ◽

pp. 9

Author(s):

Ahmed Raza ◽

Asma Mushtaq ◽

Seema Qayyum ◽

Fiza Azhar ◽

Ahmad Imran ◽

...

Keyword(s):

Histopathological Examination ◽

Cystic Teratoma ◽

Surgical Excision ◽

Unusual Site ◽

Case Presentation ◽

Neonatal Life ◽

Complete Surgical Excision ◽

Sacrococcygeal Region ◽

The Right ◽

Unilateral Proptosis

Background: Teratoma originates from all three germinal layers and commonly found at the sacrococcygeal region. The orbit is an unusual site of occurrence, but they grow rapidly and cause massive proptosis. Case Presentation: A 9-day-old female neonate presented with marked unilateral proptosis of the right eye. Imaging workup gave a suspicion of a complex mass with internal hemorrhage or a teratoma. Modified exenteration was performed. Histopathological examination revealed mature cystic teratoma. Conclusion: Orbital teratoma presents with marked disfiguring proptosis in neonatal life. Prompt complete surgical excision is curative in the case of mature lesions.

Download Full-text

Benign Lymphoepithelial Cyst: An Unusual Cause of Parotid Swelling in Two Immunocompetent Patients

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2019.577 ◽

2019 ◽

Vol 7 (13) ◽

pp. 2142-2145

Author(s):

How Kit Thong ◽

Primuharsa Putra Sabir Husin Athar ◽

Wan Muhaizan Wan Mustaffa

Keyword(s):

Histopathological Examination ◽

Surgical Excision ◽

Case Presentation ◽

Important Differential Diagnosis ◽

Immunodeficiency Virus ◽

Lymphoepithelial Cysts ◽

Parotid Swelling ◽

Slow Growing ◽

Immunocompetent Patients ◽

Hiv Negative

BACKGROUND: Lymphoepithelial cysts, which are benign and slow-growing tumours, usually involve the head and neck regions. Benign lymphoepithelial cysts (BLECs) are the most common cause of parotid swelling in human immunodeficiency virus (HIV)-positive patients and are less common in immunocompetent patients. CASE PRESENTATION: Here, we present two cases of immunocompetent patients with long-standing, progressively enlarging parotid swelling. Postoperative histopathological examination of these patients revealed features of BLEC. CONCLUSION: Wide surgical excision is the gold standard for treatment and recurrences is rare. These cases are of particular interest because of the rarity of BLEC in HIV-negative patients and highlight an important differential diagnosis of parotid swelling.

Download Full-text

Cerebral Phaeohyphomycosis: A Rare Case from South India

Iranian Journal of Neurosurgery ◽

10.32598/irjns.6.3.7 ◽

2020 ◽

Vol 6 (3) ◽

pp. 155-160

Author(s):

M. G. Sabarinadh ◽

◽

Josey T Verghese ◽

Suma Job ◽

◽

...

Keyword(s):

Clinical Symptoms ◽

Histopathological Examination ◽

Surgical Excision ◽

Dematiaceous Fungi ◽

Diagnostic Dilemma ◽

Case Presentation ◽

Fungal Brain Abscess ◽

Magnetic Resonance Imaging Mri ◽

Symptoms And Signs ◽

Cns Lesions

Background and Importance: Cerebral phaeohyphomycosis is a rare but frequently fatal clinical entity caused by dematiaceous fungi like Cladophialophora bantiana. Fungal brain abscess often presents with subtle clinical symptoms and signs, and present diagnostic dilemma due to its imaging appearance that may be indistinguishable from other intracranial space-occupying lesions. Still, certain imaging patterns on Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) help to narrow down the differential diagnosis and initiate prompt treatment of these infections. Case Presentation: A 48-year-old immunocompetent man presented with right-sided hemiparesis and hemisensory loss and a provisional diagnosis of stroke was made. The radiological evaluation suggested the possibility of a cerebral abscess. Accordingly, surgical excision of the lesion was performed and the histopathological examination of the specimen revealed the etiology as phaeohyphomycosis. The patient was further treated with antifungals and discharged when general conditions improved. Conclusion: Fungal Central Nervous System (CNS) infections present diagnostic challenges and should be considered while interpreting ring-enhancing CNS lesions in immunocompetent patients. Surgical resection and antifungal treatment should be considered in all patients with cerebral phaeohyphomycosis.

Download Full-text