Effectiveness of zinc chloride mouthwashes on oral mucositis and weight of patients with cancer undergoing chemotherapy

Abstract Background Oral mucositis is one of the most emerging and debilitating complications of chemotherapy during the treatment period, which strongly affects the nutritional status and physical and mental condition of these patients. Zinc increased protein synthesis and improved cell membrane stability so passible effective in prevent and treat oral mucositis and promote oral health. Therefore, this study aimed to evaluate the effect of zinc chloride mouthwash on the prevention, incidence, and severity of oral mucositis in cancer patients undergoing chemotherapy. Methods The present study was a randomized control trial study. 96 patients with a cancer diagnosis selected from one oncology clinic in the west of Iran. Then they assigned randomly to the zinc chloride group and placebo group. The patients in each group should rinse their mouths every 8 h two times and each time 2 min with 7.5 ml from mouthwash. The severity of mucositis and weight loss examined blindly at the baseline and 3-week follow-up. Results The incidence and severity of oral mucositis between groups were significant higher at the end of the second (p < 0.002) and third (p < 0.001) week. The mucositis severity decreased well during the third weeks in the zinc chloride group. The difference in the weight loss was significant higher between the zinc chloride and the placebo group (p < 0.01). Conclusion Zinc chloride mouthwash was effective in preventing and reducing the severity of oral mucositis and improving weight in patients undergoing chemotherapy. Trial registration We can therefore recommend more studies examine the effects zinc chloride as preventive care at the beginning of chemotherapy to improve oral health and subsequently preventing weight loss in these patients.

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Effectiveness of Zinc Chloride Mouthwashes on Oral Mucositis and Weight of Patients with Cancer Undergoing Chemotherapy

10.21203/rs.3.rs-241778/v1 ◽

2021 ◽

Author(s):

khodayar oshvandi ◽

Seyed Yaser Vafaei ◽

Seyed Ramesh Kamallan ◽

Salman Khazaei ◽

Hossein Ranjbar ◽

...

Keyword(s):

Weight Loss ◽

Placebo Group ◽

Oral Health ◽

Oral Mucositis ◽

Zinc Chloride ◽

Mental Condition ◽

Cell Membrane Stability ◽

Patients With Cancer ◽

The Difference ◽

The University

Abstract Background: Oral mucositis is one of the most emerging and debilitating complications of chemotherapy during the treatment period, which strongly affects the nutritional status and physical and mental condition of these patients. Zinc can efficiently prevent and treat oral mucositis and promote oral health due to its increased protein synthesis and improved cell membrane stability and membrane wound healing. Therefore, this study aimed to evaluate the effect of zinc chloride mouthwash on the prevention, incidence, and severity of oral mucositis in cancer patients undergoing chemotherapy.Methods: The present study was a randomized control trial study.96 patients with a cancer diagnosis selected from one oncology clinic affiliated to the University of Medical Sciences in western Iran. Then they assigned randomly to the zinc chloride group and placebo group. The patients in each group should rinse their mouths every 8 hours two times and each time 2 min with 7.5 ml from mouthwash. The severity of mucositis and weight loss examined blindly at the baseline and 3-week follow-up.Results: The incidence and severity of oral mucositis between groups was significant at the end of the first (p < 0.026), second (p < 0.002) and third (p < 0.001) week. The mucositis severity controlled welly during the third weeks in the zinc chloride group. The difference in the weight loss was significant between the zinc chloride and the placebo group (p < 0.01).Conclusion: Zinc chloride mouthwash was effective in preventing and reducing the severity of oral mucositis and improving weight in these patients, and can be recommended for patients undergoing chemotherapy.Trial registration: We can therefore recommend zinc chloride as preventive care at the beginning of chemotherapy to improve oral health and subsequently preventing weight loss in these patients.

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Oral Status and Dementia Onset: Mediation of Nutritional and Social Factors

Journal of Dental Research ◽

10.1177/00220345211049399 ◽

2021 ◽

pp. 002203452110493

Author(s):

S. Kiuchi ◽

U. Cooray ◽

T. Kusama ◽

T. Yamamoto ◽

H. Abbas ◽

...

Keyword(s):

Weight Loss ◽

Oral Health ◽

Social Factors ◽

Evaluation Study ◽

Baseline Survey ◽

Fruit Intake ◽

Number Of Teeth ◽

Stratified Analysis ◽

Dementia Onset

Some modifiable risk factors for dementia are closely related to oral health. Although eating and speaking abilities are fundamental oral functions, limited studies have focused on the effect of malnutrition and lack of social interaction between oral health and dementia. We investigated the mediating effects of nutritional and social factors on the association between the number of teeth and the incidence of dementia. This 6-y cohort study used data from the Japan Gerontological Evaluation Study targeting older adults aged 65 y and above. The number of teeth (exposure) and covariates in 2010 (baseline survey), mediators (weight loss, vegetable and fruit intake, homeboundness, social network) in 2013, and the onset of dementia (outcome) between 2013 and 2016 were obtained. The Karlson–Holm–Breen mediation method was applied. A total of 35,744 participants were included (54.0% women). The mean age at baseline was 73.1 ± 5.5 y for men and 73.2 ± 5.5 y for women. A total of 1,776 participants (5.0%) had dementia during the follow-up period. There was a significant total effect of the number of teeth on the onset of dementia (hazard ratio, 1.14; 95% CI, 1.01–1.28). Controlling for nutritional and social mediators, the effect of the number of teeth was reduced to 1.10 (95% CI, 0.98–1.25), leaving an indirect effect of 1.03 (95% CI, 1.02–1.04). In the sex-stratified analysis, the proportion mediated by weight loss was 6.35% for men and 4.07% for women. The proportions mediated by vegetable and fruit intake and homeboundness were 4.44% and 4.83% for men and 8.45% and 0.93% for women, respectively. Furthermore, the proportion mediated by social networks was 13.79% for men and 4.00% for women. Tooth loss was associated with the onset of dementia. Nutritional and social factors partially mediated this association.

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Abstract P199: Keep Moving, Your Health Depends On It: Impact Of Improved Physical Activity And Weight Loss In A Wellness Program

Circulation ◽

10.1161/circ.129.suppl_1.p199 ◽

2014 ◽

Vol 129 (suppl_1) ◽

Author(s):

Ebenezer T Oni ◽

Ehimen Aneni ◽

Maribeth Rouseff ◽

Thinh Tran ◽

Henry Guzman ◽

...

Keyword(s):

Physical Activity ◽

Blood Pressure ◽

Weight Loss ◽

Intervention Program ◽

South Florida ◽

Metabolic Equivalents ◽

Baseline Weight ◽

The Mean ◽

The Difference

Negative impact of CVD as the leading cause of death in the US is worsened by the significant burden of obesity and associated morbidity and concerns about the growing population inactivity. The American Heart Association has emphasized worksite-based interventions to improve CV health. We evaluated the benefits of improved physical activity(PA) and weight loss(WL) among employees of the Baptist Health South Florida enrolled in a wellness intervention program. Methods: Employees with two or more Cardio-metabolic risk factors , such as total cholesterol ≥ 200 mg/dl, systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg, hemoglobin A1C ≥ 6.5%, and body mass index (BMI) ≥ 30 were enrolled in an intervention program themed “My unlimited potential”. Interventions were focused on diet and PA modifications. We defined improved physical activity as the difference in the metabolic equivalents (METs) at 12 weeks follow-up and at baseline. WL (lbs) was the difference in weight at follow-up. The relationship between WL and changes in METs was explored in an ordered logistic regression. Results: Overall 203 (48±10 years, 78% females) employees were enrolled with a retention rate of 89% (n=181) at 12 weeks follow-up. At baseline the median weights was 211 lbs., and mean METs- 8.6, while at follow-up the median weight was 200 lbs, and the mean METs 11. At 12 weeks follow up 38% had significant WL (lost >5% of baseline weight). The median WL was 8.4 (IQR 4.8-13.0) lbs and the mean change in METs was 2.4±1.8. Median WL increased with increasing tertiles of METs change; tertile1- 6.5(4-11) lbs., tertile2- 9(6-13)lbs. tertile3- 11(7-15)lbs. Increased PA was related to increased WL across BMI categories adjusting for age, gender and baseline weight. Conclusion: This study points strongly toward the benefit of increasing PA among other lifestyle modification interventions in controlling weight. Although further follow-up of this population to evaluate sustainability of change is needed, our results clearly relate improved PA and health.

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Efficacy of a Traditional Herbal Formula, Banha-Sasim-Tang in Functional Dyspepsia Classified as Excess Pattern

Frontiers in Pharmacology ◽

10.3389/fphar.2021.698887 ◽

2021 ◽

Vol 12 ◽

Author(s):

Yun Hee Kim ◽

Jun Young Kim ◽

O-Jin Kwon ◽

So Young Jung ◽

Jin-Yong Joung ◽

...

Keyword(s):

Placebo Group ◽

Functional Dyspepsia ◽

Control Group ◽

Medication Regimen ◽

Clinical Trial Registration ◽

Vas Score ◽

Treatment Administration ◽

The Difference

This study evaluated the efficacy and safety of Banha-sasim-tang (BST) in patients with functional dyspepsia (FD). BST (Banxia-xiexin-tang in traditional Chinese medicine and Hange-shashin-to in Kampo medicine) is traditionally prescribed for the treatment of dyspepsia with epigastric stiffness and gastric fullness in China, Japan, and Korea. Patients with FD were randomly administered an oral dose (10 g) of BST syrup or placebo, twice a day for 4 weeks. The primary outcome was the symptom checklist part of the Nepean dyspepsia index (NDI). The secondary outcomes were the quality of life (QoL) part of the NDI, functional dyspepsia-related QoL (FD-QoL), and visual analog scale (VAS). A total of 60 patients with FD were screened, and 50 were randomized into BST group (n = 25) and placebo group (n = 25). Two patients in the placebo group withdrew before the start of the treatment. Administration of BST syrup resulted in improvement in the symptom-related NDI score in the BST group compared with that in the control group; however, the difference was not significant. BST syrup significantly improved “fullness after eating” index of NDI at follow-up time point (2.88 ± 2.65 vs 4.78 ± 2.69, p = 0.0081). In the total score of the QoL section of the NDI and FD-QoL scales, there was no significant improvement in the BST group compared to that in the placebo group. With regard to improvement in overall FD symptoms, the VAS scale showed improvement in both groups, but the difference was not significant. Interestingly, follow-up investigation showed a significantly beneficial effect of BST on FD symptoms, when compared to placebo. Significant improvement observed in VAS score (39.60 ± 22.29 vs 52.17 ± 20.55, p = 0.048). This indicated that the effect of BST lasted even after the completion of the medication regimen. Overall, our data suggest that while BST showed no significant improvement in the symptom-related NDI score and the QoL related scores in NDI and FD-QoL after 4 weeks of treatment, it effectively improved the VAS score and fullness after eating-related symptoms in the follow-up visit.Clinical Trial Registration:https://cris.nih.go.kr; Identifier KCT 0002013

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Bariatric endoscopy procedure type or follow-up: What predicted success at 1 year in 962 obese patients?

Endoscopy International Open ◽

10.1055/a-1007-1769 ◽

2019 ◽

Vol 07 (12) ◽

pp. E1691-E1698 ◽

Cited By ~ 2

Author(s):

Gontrand Lopez-Nava ◽

Ravishankar Asokkumar ◽

Angel Rull ◽

Fernandez Corbelle ◽

Lucia Beltran ◽

...

Keyword(s):

Weight Loss ◽

Logistic Regression ◽

Body Weight Loss ◽

Total Body Weight ◽

University Hospital ◽

Bariatric Endoscopy ◽

Weight Loss Outcomes ◽

The Difference ◽

Procedure Type

Abstract Background and study aims It is uncertain if the difference in weight loss outcomes between different endoscopic bariatric therapies (EBTs) is technique-related or multidisciplinary team (MDT) follow-up-related. We hypothesized that at 1 year, the weight loss is determined more by adherence to MDT follow-up than by procedure type. We aimed to compare 1 year weight loss outcomes of four different EBTs at a single center with a standardized MDT follow-up. Patients and methods We prospectively collected and retrospectively analyzed outcomes in 962 patients (female-691, 71.2 %; mean age, 44.8 ± 10.6 years, mean BMI, 37.8 ± 5.9 Kg/m2) treated with Intragastric balloons (IGBs) or endoscopic gastroplasty (EG) at HM Sanchinarro University Hospital between March 2012 to January 2017. The procedures were performed by the same endoscopist and followed up by the same MDT. We compared the percentage total body weight loss (%TWBL) at 1 year. We performed linear and logistic regression to identify predictive factors for weight loss and follow-up adherence at 1 year. Results Four hundred and eighty-one IGBs (Orbera-80.9 %; ReShape Duo-19.1 %), and 481 EG (Apollo ESG-51.3 %; Primary obesity surgery endoluminal-POSE-48.6 %) were performed. Only 480 patients (IGB- 45 %; EG- 55 %) completed 1 year follow-up. Among them, Apollo ESG achieved significantly higher TBWL (19.5 ± 13 %, P = 0.035), %TBWL (17.4 ± 10.2 %, P = 0.025), and ≥ 20 % TBWL (36.7 %, P = 0.032). However, in linear regression after adjusting for variables, only higher initial BMI (B = 0.31, P < 0.001) and higher percentage follow-up attendance (B = 0.24, P < 0.001) significantly predicted %TBWL at 1 year in the completion group but not the procedure type (B = 0.02, P = 0.72). In logistic regression, we observed female sex (P = 0.01), high initial BMI (P < 0.001), endoscopic gastroplasty (P = 0.04), and high 1-month %TBWL (P < 0.001) significantly predicted follow-up completion at 1 year. Conclusions Weight loss at 1 year is dependent on MDT follow-up rather than procedure type. Endoscopic gastroplasty promoted follow-up adherence more than IGBs.

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EFIKASI TAMSULOSIN PADA BENIGN PROSTATIC HYPERPLASIA DENGAN RETENSIO URINE AKUT YANG MENJALANI TRIAL WITHOUT CATHETER

Indonesian Journal of Urology ◽

10.32421/juri.v16i2.337 ◽

1970 ◽

Vol 16 (2) ◽

Author(s):

Khoirul Kholis ◽

Soetojo Soetojo ◽

Tarmono Djojodimedjo ◽

Widodo J P

Keyword(s):

Placebo Group ◽

Urinary Retention ◽

Acute Urinary Retention ◽

Chi Square ◽

Urine Retention ◽

Post Test ◽

Chi Square Test ◽

Trial Without Catheter ◽

The Difference

Objective: To evaluate the efficacy of tamsulosin on BPH patients with acute urinary retention on trial without catheter (TWOC). Materials & method: This study was a post test only-placebo group design comparing residual urine in BPH patients with acute urinary retention on TWOC between groups administered with tamsulosin and placebo. The efficacy of both groups with tamsulosin and placebo on the 3rd and 14th day was analyzed using Chi Square test while the efficacy of administration of tamsulosin and placebo on the 3rd and 14th day was analized using Mc Nemar test. Results: This study showed that there was still urinary retention in 7 patients (58,3%) and 4 patients (44,4%) shared recovery within 3 days of tamsulosin administration, while 5 patients (41,7%) still had urinary retention compared to 5 patients (55,6%) who showed recovery in the placebo group. The difference was insignificant with p=0,670. Patients who dropped out from TWOC on the 3rd day and given tamsulosin until the 14th day showed urinary retention in 4 patients (44,4%) and recovery in 3 patients (100%) while all samples who were given placebo showed urinary retention 5 patients (55,6%). The difference was insignificant with p=0,205. Follow up for 3 days in Tamsulosin groups which have urine retention in this study, 3 patients became free for urine retention and the other 4 patients still had urine retention. But in this study, no difference in efficacy with p=1,025. In placebo groups with urinary retention before the 3rd day of administration still showed urinary retention after the 14th day. Conclusion: There was no statistical differences on the success of TWOC, between groups administered with 0,2 mg of tamsulosin and placebo group, neither on the 3rd day nor on the 14th day. There was reduction of recatheterization because of failure of TWOC with patients who were given tamsulosin for 14 days.

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A reális és irreális testsúlycélok motivációs szerepe a fogyásban.

Orvosi Hetilap ◽

10.1556/650.2021.32128 ◽

2021 ◽

Vol 162 (28) ◽

pp. 1119-1128

Author(s):

Dóra Perczel-Forintos ◽

Ildikó Kohlné Papp ◽

Gabriella Vizin ◽

Márton Kiss-Leizer

Keyword(s):

Weight Loss ◽

Eating Behavior ◽

Social Consequences ◽

Behavioral Approach ◽

Cognitive Behavioral ◽

Excess Body Weight ◽

Behavioral Weight Loss ◽

The Difference ◽

Successful Weight Loss

Összefoglaló. Bevezetés: Az elhízás korunk egyik legnagyobb kihívása, hiszen a többletsúly számos krónikus betegség kockázati tényezője, és fontos pszichés és szociális következményei vannak. A kezelésben bizonyítottan hatékony a kognitív viselkedésterápiás testsúlycsökkentő program, amelynek során alapvető fontosságú a reális célsúly meghatározása, ugyanis az irreális elvárások megakadályozhatják a hosszú távú sikeres testsúlykontrollt. Célkitűzés: Prospektív kutatásunk kérdése, hogy az elérhető fogyást milyen mértékben befolyásolják a testsúlycélok a kognitív viselkedésterápiás testsúlycsökkentő program során. Feltételeztük, hogy a testsúlycsökkentő csoport résztvevői irreális fogyási elvárásokkal érkeznek, melyek azonban reálisabbá válnak a program végére, és megmaradnak az utánkövetés idejére. Emellett feltételeztük, hogy a testsúlycsökkentő program során az evési magatartás pozitív irányban fog változni. Módszer: A 24 hetes testsúlycsökkentő programban 63, az egyéves utánkövetésben pedig 49 felnőtt vett részt. A résztvevők antropometriai mutatói mellett (testtömeg, testmagasság) az evési magatartást és a testsúlycélokat a Háromfaktoros Evési Kérdőívvel, illetve a Célok és Relatív Testsúlyok Kérdőívvel mértük fel. Eredmények: A résztvevők közel 90%-a elérte a professzionális testsúlycsökkentő módszerek esetében elvárható legalább 5–10%-os fogyást, az evési magatartás pozitív irányban változott, testsúlycéljaik reálisabbak lettek. A fogyás szignifikáns, fordított kapcsolatban volt az aktuális és az álomsúly, az aktuális és a vágyott, valamint az aktuális és az elfogadható testsúly közötti eltéréssel. Következtetés: A kognitív viselkedésterápia széles körben alkalmazható, hatékony testsúlycsökkentő módszer, amelynek sikerében fontos szerepet játszanak a reálisan kitűzött testsúlycélok. Orv Hetil. 2021; 162(28): 1119–1128. Summary. Introduction: Obesity has become one of the most challenging issues, as the excess body-weight is a risk factor for numerous chronic diseases and has serious psychological and social consequences. The cognitive behavioral approach to weight loss had been shown an effective treatment, in which realistic weight target setting is essential, because unrealistic expectations can hinder the effort for a successful long-term weight management. Objective: The objective of our prospective study was to investigate as to how weight loss is influenced by realistic and unrealistic weight targets in a cognitive behavioral weight loss program. We hypothesized that the participants come with unrealistic weight loss expectations, which become more realistic by the end of the program and remain realistic for the follow-up. In addition, a positive change was expected in the eating behavior of the participants during the program. Method: The program was completed by 63 people, 49 subjects participated in the 1-year follow-up. Anthropometric data were obtained and the participants were asked to fill in the Three-Factor Eating Questionnaire – Revised 21 items and the Goals and Relative Weights Questionnaire. Results: According to the results, the program is effective, since nearly 90% of the participants reached at least 5–10% weight loss as expected by professional weight loss methods. Besides weight loss there were positive changes in the participants’ eating behavior; weight targets became more realistic. Weight loss was inversely related to the difference between actual and dream, actual and desired as well as between actual and acceptable weight. Conclusion: Our results in accordance with previous studies show that cognitive behavioral weight loss programs can be effective; however, setting up realistic weight targets can be crucial in successful weight loss. Orv Hetil. 2021; 162(28): 1119–1128.

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The Role of Trigonella, Cichorium, and Foeniculum Herbal Combination in the Treatment of Cancer-Induced Anorexia/Cachexia: A Quasi-Experimental Study

International Journal of Cancer Management ◽

10.5812/ijcm.102515 ◽

2020 ◽

Vol 13 (8) ◽

Author(s):

Amirreza Famil-Dardashti ◽

Ali Hajigholami ◽

Shirinsadat Badri ◽

Afsaneh Yekdaneh ◽

Azadeh Moghaddas

Keyword(s):

Quality Of Life ◽

Experimental Study ◽

Weight Loss ◽

Placebo Group ◽

Weight Gain ◽

Combination Group ◽

Anthropometric Indices ◽

Quasi Experimental

Background: Anorexia and cachexia are one of the major problems in patients suffering from advanced malignancies. Objectives: This study aimed at evaluating the efficacy of herbal combination containing Fenugreek, Fennel, and Chicory supplementation to the high-dose megestrol for the treatment of cancer-induced cachexia and anorexia. Methods: This quasi-experimental study was performed on 47 adult patients with advanced malignancy; they experienced anorexia and weight loss over the 2 past months and referred to a university-affiliated hospital (Omid) in Isfahan, Iran. Patients who had met the inclusion criteria were assigned to take either herbal combination or placebo tablets in addition to megestrol (160 mg daily) for a 2-month follow-up. All patients’ demographic information, weight changes, anthropometric indices, as well as the quality of life criteria were recorded at the baseline and after the duration of follow-up. Results: Patients in the herbal combination group experienced a mean weight gain of 1.5 kg, while patients in the placebo group had an average weight loss of 0.6 kg. Anthropometric indices including triceps skinfold thickness, mid-arm muscle circumference index, and grip strength were significantly improved in the herbal combination group. The other evaluated criteria such as quality of life, functional assessment of anorexia/cachexia therapy (FAACT), and some factors of Anderson criteria were significantly improved in the herbal combination group than the placebo group. Conclusions: Given the ameliorated results of the herbal combination supplementation in terms of weight gain and appetite improvement, as well as physical and quality of life enhancement, it seems that the herbal combination can be used as an adjunctive treatment for the management of patients suffering from cancer-induced cachexia and anorexia.

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Effect of 5 + 2 Intermittent Fasting Mode on Body Weight of Chinese Overweight/Obese Adults Under Meal Replacement Mode: A Randomized Controlled Study

Current Developments in Nutrition ◽

10.1093/cdn/nzaa063_017 ◽

2020 ◽

Vol 4 (Supplement_2) ◽

pp. 1619-1619

Author(s):

Wei Chen ◽

Fei Liu ◽

Xiaodong Shi

Keyword(s):

Weight Loss ◽

Loss Rate ◽

Intermittent Fasting ◽

Average Weight ◽

Meal Replacement ◽

Weight Loss Rate ◽

Significant Difference ◽

The Difference ◽

Ordinary Diet

Abstract Objectives 5 + 2 intermittent fasting is a safe and effective method for weight loss (eat normally for 5 days, and give 1/4 of the required calorie for the other 2 consecutive days in 1 week). However, because of the obvious hunger and poor energy control, it is difficult to implement the plan. This study hypothesis that based on the 5 + 2 intermittent fasting mode, replacing the ordinary diet with an equivalent energy meal replacement product can reduce the sense of hunger and improve the implementation capability by adjusting nutrition composition and ratio. Methods This study was a parallel randomized control design. A total of 100 participants were included, and they were randomly divided into meal replacement (MR) group and ordinary diet (OD) group according to the random number table method for a total of 12-week observation. At baseline, height, body weight (BW), grip strength (GS), blood pressure (BP), heart rate (HR), laboratory-related indicators, and body composition (BC) were measured. Follow-up was performed at week 4, 8, and 12, and BW, GS, waist circumference (WC), hip circumference (HC), BP, HR, BC, hunger, satiety, and dietary satisfaction scores were measured. Laboratory indicators were retested at week 12. Physical exercise was not forced during observation. Results After 12 weeks, the MR group lost 5.1 ± 3.31 kg, and the average weight loss rate was 6.6%. It was significant difference to the baseline (P < 0.0001). The OD group lost 4.89 ± 4.5 kg, and the average weight loss rate was 6.1% (P < 0.0001). There was no significant difference in weight loss between two groups (P = 0.114). The reduction in BMI between two groups was increased with the observation time, and the difference between two groups gradually increased, but the difference was not significant at week 12 (P = 0.668). Compared to the baseline, differences in visceral fat area and body fat ratio between my two groups were significant (P < 0.0001). There were no significant differences in HR, BP, GS, WC, HC, blood lipid and blood glucose, hunger, satiety, and dietary satisfaction scores between the two groups at each follow-up. Conclusions The effect of 5 + 2 intermittent fasting mode on weight loss was significant without physical exercise. Safety and efficacy of weight loss in MR group were equivalent to OD group, but meal replacement was more convenient for those who could not prepare their own meals. Funding Sources None.

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Re-Increased Male Suicide Rates in the Recovery Phase Following the Great East Japan Earthquake

Crisis ◽

10.1027/0227-5910/a000656 ◽

2020 ◽

Vol 41 (6) ◽

pp. 422-428 ◽

Cited By ~ 1

Author(s):

Masatsugu Orui

Keyword(s):

Social Connectedness ◽

Recovery Phase ◽

Great East Japan Earthquake ◽

Temporary Housing ◽

Period Analysis ◽

Suicide Rates ◽

Male Suicide ◽

The Social ◽

The Difference

Abstract. Background: Monitoring of suicide rates in the recovery phase following a devastating disaster has been limited. Aim: We report on a 7-year follow-up of the suicide rates in the area affected by the Great East Japan Earthquake, which occurred in March 2011. Method: This descriptive study covered the period from March 2009 to February 2018. Period analysis was used to divide the 108-month study period into nine segments, in which suicide rates were compared with national averages using Poisson distribution. Results: Male suicide rates in the affected area from March 2013 to February 2014 increased to a level higher than the national average. After subsequently dropping, the male rates from March 2016 to February 2018 re-increased and showed a greater difference compared with the national averages. The difference became significant in the period from March 2017 to February 2018 ( p = .047). Limitations: Specific reasons for increasing the rates in the recovery phase were not determined. Conclusion: The termination of the provision of free temporary housing might be influential in this context. Provision of temporary housing was terminated from 2016, which increased economic hardship among needy evacuees. Furthermore, disruption of the social connectedness in the temporary housing may have had an influence. Our findings suggest the necessity of suicide rate monitoring even in the recovery phase.

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