scholarly journals Antibacterial and anti-Trichomonas Vaginalis effects of Rosa Damascena mill petal oil (a persian medicine product), aqueous and hydroalcoholic extracts

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fatemeh Saghafi ◽  
Farzaneh Mirzaie ◽  
Elham Gorji ◽  
Razieh Nabimeybodi ◽  
Mehdi Fattahi ◽  
...  
Keyword(s):  
Trichomonas Vaginalis ◽  
Rosa Damascena ◽  
Inhibition Activity ◽  
Antibacterial Effects ◽  
Hydroalcoholic Extract ◽  
Persian Medicine ◽  
Rose Oil ◽  
Group B ◽  
Medicine Product

Abstract Background Oils in traditional medicine are important products and used routinely for therapeutic purposes. Rose oil (Rosa damascene Mill), a product of Persian medicine, is advised for the treatment of Infectious diseases related to the female genitourinary tract. In the present study, R. damascena petal oil, aqueous, and hydroalcoholic extracts were evaluated for their in vitro antibacterial and anti-Trichomonas vaginalis effects. Methods Anti-trichomonas activity evaluation of extracts and oil were assayed by the Homocytometery method. Their antibacterial effects against Escherichia coli, methicillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa, and clinically isolated Group B Streptococcus were assayed by broth microdilution in 96-well plates. Results The MIC of hydroalcoholic and aqueous extracts ranged from 25-50 and 25-100 mg/ml, respectively. Rose oil at all administered doses failed to show any antibacterial activity. Conclusion All extracts and oil concentrations showed some degree of growth inhibition activity on T. vaginalis; however, hydroalcoholic extract was more efficient.

Phytochemical analysis of olive flowers' hydroalcoholic extract and in vitro evaluation of tyrosinase, elastase and collagenase inhibition activity

Fitoterapia ◽  
2020 ◽  
Vol 143 ◽  
pp. 104602 ◽  
Author(s):  
Apostolis Angelis ◽  
Panagiotis Mavros ◽  
Panagiota Efstathia Nikolaou ◽  
Sofia Mitakou ◽  
Maria Halabalaki ◽  
...  
Keyword(s):  
Phytochemical Analysis ◽  
Inhibition Activity ◽  
Hydroalcoholic Extract ◽  
In Vitro Evaluation ◽  
Collagenase Inhibition

scholarly journals Antibacterial Effects of Hydroalcoholic and Aqueous Extracts of Two Medicinal Plants in Comparison with Popular Antibiotics: An In Vitro Study

2020 ◽  
Vol 22 (4) ◽  
Author(s):  
Sadra Ansaripour ◽  
Niloofar Safaei ◽  
Najme Bagheri
Keyword(s):  
Acinetobacter Baumannii ◽  
In Vitro Study ◽  
Diffusion Method ◽  
Aqueous Extracts ◽  
Broth Microdilution ◽  
Antibacterial Effects ◽  
Disk Diffusion Method ◽  
Hydroalcoholic Extract ◽  
Mean Diameter

Background: Acinetobacter baumannii is considered a dangerous and drug-resistant hospital-acquired infection. Nowadays, there has been an increasing interest in the use of herbal drugs. Objectives: This in vitro study was conducted to determine the antimicrobial effects of Rumex acetosella L. and Cucurbita maxima L. on Acinetobacter baumannii in comparison with popular antibiotics. Methods: In this experimental study, after extraction, the antibacterial effects of extracts were determined based on MIC and MBC using broth microdilution. The effects of different concentrations of the extracts on A. baumannii growth were also investigated by the disk diffusion method. The results were compared with choice antibiotics. Results: The results of the study indicated that in broth microdilution, the MIC and MBC of the hydroalcoholic extract of C. maxima and the aqueous extract of R. acetosella were equal (64 and 128 µg/mL, respectively). The MIC and MBC of the hydroalcoholic extract of R. acetosella and the aqueous extract of C. maxima were 128 and 256 µg/mL, respectively, which indicated the weaker effects of these extracts. In the disk diffusion method, the greatest mean diameter of inhibition zone was obtained for R. acetosella extracts (24.83 ± 0.29 and 21.83 ± 0.29 mm for hydroalcoholic and aqueous extracts, respectively). Also, the lowest mean diameter was obtained for C. maxima extracts (10.33 ± 0.58 and 8 mm for hydroalcoholic and aqueous extracts, respectively). Conclusions: This study showed the potent antibacterial effects of R. acetosella and C. maxima. They were even more potent than commonly used antibiotics. Therefore, the plants can be used as antimicrobial agents, as well as pharmaceutical supplements and alternative therapies.

scholarly journals Inhibitory effect of hydroalcoholic extract of Cestrum Nocturnum on α-amylase activity

2018 ◽  
Vol 6 (03) ◽  
pp. 52-54
Author(s):  
Anil Kamboj
Keyword(s):  
Amylase Activity ◽  
Inhibitory Effect ◽  
Vital Role ◽  
Postprandial Hyperglycemia ◽  
Inhibition Activity ◽  
Hydroalcoholic Extract ◽  
Aerial Parts ◽  
Ic50 Value ◽  
Natural Inhibitors

Inhibition of α- amylase play a vital role in the clinical management of postprandial hyperglycemia. Although, powerful synthetic inhibitors are available, natural inhibitors are potentially safer. The present study was carried out to evaluate α- amylase inhibition activity from hydroalcoholic extracts from aerial parts of Cestrum nocturnum. Hydroalcoholic extract was prepared by Soxhletation Method. The extract showed strong inhibition towards α- amylase activity and IC50 value were 45.9 μg. This In vitro studies indicate the potential of C. nocturnum in the development of effective anti-diabetic agents.

scholarly journals In vitro Anti-candida Activity of Different Saudi Honeys and Honey Mixed with Taifi Rose Oil

2019 ◽  
Vol 16 (04) ◽  
pp. 779-787 ◽  
Author(s):  
Anan Kalakattawi ◽  
Sana G. Al Attas ◽  
Sherif Edris ◽  
Ahmed Z. Abdel Azeiz ◽  
Ahmad F. AlGuthami ◽  
...  
Keyword(s):  
Mass Spectrometry Analysis ◽  
Vaginal Candidiasis ◽  
Therapeutic Drug ◽  
Rosa Damascena ◽  
Disease Treatment ◽  
Spectrometry Analysis ◽  
Geographic Origins ◽  
Wide Range ◽  
Rose Oil

ABSTRACT: Candida albicans is a common human yeast that infect several epithelial tissues including vagina. The increase of drug-resisting C. albicans encouraged the researchers to find alternative treatment. Honey medical signatures such as bactericidal, antifungal and anti-candida made it a possible candidate for disease treatment. In addition, rose essential oil possesses a wide range of biochemical activities in folkloric medicine including anti-microbial activities. The present research utilizes honey alone or in conjunction with Taifi rose (Rosa damascena) oil as anti-candida agent to treat vaginal candidiasis. Three local monof oral honeys from different flower sources and/or geographic origins were tested with four concentrations (50, 80 and 95%), while two concentrations of the Taifi rose oil (1 and 2%). anti-candida activity of honey alone or in conjunction with Taifi rose oil was determined as well as phenolic and flavonoids contents were determined. Also, GC-MS analysis of volatile oils and alkaloids were evaluated. The results of this study indicated that acidity is within the allowed range for commercialization and long-lasting storage. All honeys tested inhibited completely the C. albicans growth at concentrations 80% and 95% either incubation after 48 or 72 h. Also, only Markh and Manuka honeys were completely inhibited C. albicans growth at 50% concentration. Also, C. albicans growth inhibited completely at 2% Taifi rose oil after the incubation periods of 48 and 72 h. The phenolic compounds and flavonoids were analysed by mass spectrometry analysis which revealed the Markh honey showed the presence of gallic acid and quercetin that proved to have antifungal activity. It could be concluded that mixed Markh honey and Taifi rose oil treatment was capable to inhibit C. albicans growth completely. Further research is required to determine the anti-candida activity of the mixture of Markh honey and Taifi rose oil in the human body as a new therapeutic drug to treat vaginal candidiasis.

Efficacy of Punica granatum extract on in vitro and in vivo control of Trichomonas vaginalis

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
GT El Sherbini ◽  
KM Ibrahim ◽  
ET El Sherbini ◽  
NM Abdel Hady ◽  
TA Morsy
Keyword(s):  
Trichomonas Vaginalis ◽  
Punica Granatum

Factor II Related Antigen and Antithrombin III Levels as Indicators of Liver Failure in Consumption Coagulopathy

1982 ◽  
Vol 47 (03) ◽  
pp. 218-220 ◽  
Author(s):  
P Sié ◽  
E Letrenne ◽  
C Caranobe ◽  
M Genestal ◽  
B Cathala ◽  
...  
Keyword(s):  
Liver Failure ◽  
Antithrombin Iii ◽  
Coagulation Factors ◽  
Consumption Coagulopathy ◽  
Blood Coagulation Factors ◽  
Factor Ii ◽  
At Iii ◽  
Group A ◽  
Group B

SummaryIn order to detect impaired synthesis of blood coagulation factors associated to consumption coagulopathy, a simultaneous evaluation of factor II-related antigen (II rAg) and of antithrombin III (AT III) was carried out in 16 patients affected with severe defibrination. An in vitro preliminary study on plasma and serum demonstrated that the levels of II rAg and of AT III, assessed by the Laurell technique with Behring antisera, were not reduced by the coagulation process. The patients were, a posteriori, classified into two groups according to the absence (group A) or the presence (group B) of factors predisposing to liver failure such as metastasis, cirrhosis, and prolonged shock. II rAg and AT III levels are significantly correlated; they are in the normal range in group A but reduced in group B. Thus II rAg or AT III level determinations are useful markers in the detection of liver failure associated to the consumption phenomenon. These results also suggest that part of the decreased AT III levels reported in severe cases of disseminated intravascular coagulation may be the consequence of an associated liver failure.

Comparative Study to Evaluate the Surface Detail Reproduction of Dental Stone after Immersion in Various Different Disinfectant Solutions, Under Stereomicroscope 10 X Magnification –An In-Vitro Study

2017 ◽  
Vol 9 (3) ◽  
Author(s):  
Rathika Rai ◽  
M. A. Easwaran ◽  
K. T. Dhivya
Keyword(s):  
Sodium Hypochlorite ◽  
In Vitro Study ◽  
Control Group ◽  
Immersion Method ◽  
Significant Difference ◽  
Surface Irregularities ◽  
Disinfectant Solution ◽  
Surface Detail ◽  
Group B

Aim: To evaluate the surface detail reproduction of dental stone this is immersed in different disinfectant solution and studied under stereomicroscope. Methodology: Total number of 30 specimens of dental stone (Type III) were made with measurements of 1.5cm diameter and 1cm height .This samples are divided in to 3 groups group A,B,C. were A is immersed in Distilled water which was taken as control group ;B is immersed in 2% Glutaraldehyde and C is immersed in 5%sodium hypochlorite. Each specimen were immersed in the disinfectant solution for 15 minutes and dried under room temperature for 24 hrs. After 24 hrs each specimens are studied under stereomicroscope for surface details. Result: The results showed no significant difference in the surface irregularities and porosities for a group 1 and group 2 except group 3 which showed significant increase in the porosities, surface irregularities and erosions after disinfection with 5% NaHOCl by immersion method. Conclusion: The surface detail reproduction capacity of die stone was adversely affected when 5% Sodium hypochlorite was used as disinfectant solution when compare d to control group and 2% Glutaraldehyde

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