scholarly journals Severe vivax malaria trends in the last two years: a study from a tertiary care centre, Delhi, India

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Monika Matlani ◽  
Loick P. Kojom ◽  
Neelangi Mishra ◽  
Vinita Dogra ◽  
Vineeta Singh
Keyword(s):  
Severe Malaria ◽  
Disease Severity ◽  
Vivax Malaria ◽  
Severe Disease ◽  
Tertiary Care ◽  
Peripheral Blood Smear ◽  
Severe Anaemia ◽  
Significant Shift ◽  
Care Centre ◽  
Tertiary Care Centre

Abstract Background Plasmodium vivax, once considered benign species, is recently being recognised to be causing severe malaria like Plasmodium falciparum. In the present study, the authors report the trends in malaria severity in P. vivax among patients from a Delhi government hospital. The aim of the study was to understand the disease severity and the burden of severe vivax malaria. Methods A hospital based study was carried out from June 2017 to December 2018 at a tertiary care centre from Delhi, India. Patients were tested for malaria using peripheral blood smear (PBS) and/or rapid malaria antigen test (RMAT). The severe and non-severe vivax malaria categorization was done as per the WHO guidelines. Sociodemographic, clinic and paraclinical data were collected from patients and their medical records. Results Of the 205 patients, 177 (86.3%) had P. vivax infection, 22 (10.7%) had P. falciparum infection and six (2.9%) had mixed infection with both the species. Out of 177 P. vivax cases included in this study one or more manifestations of severe malaria was found in 58 cases (32.7%). Severe anaemia (56.9%), jaundice (15%) and significant bleeding (15%) were the most common complications reported in most of patients, along with thrombocytopenia. Conclusions In this study, it is evident that vivax malaria is emerging as the new severe disease in malaria patients, a significant shift in the paradigm of P. vivax pathogenesis. The spectrum of complications and alterations in the laboratory parameters in P. vivax clinical cases also indicate the recent shift in the disease severity.

25-Hydroxy vitamin D levels in chronic urticaria and its correlation with disease severity from a tertiary care centre in South India

2014 ◽  
Vol 52 (6) ◽  
Author(s):  
Laxmisha Chandrashekar ◽  
Medha Rajappa ◽  
Malathi Munisamy ◽  
Palghat Hariharan Ananthanarayanan ◽  
Devinder Mohan Thappa ◽  
...  
Keyword(s):  
Vitamin D ◽  
Disease Severity ◽  
Chronic Urticaria ◽  
South India ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Vitamin D Levels ◽  
25 Hydroxy Vitamin D

scholarly journals Clinico-hematological manifestations of malaria in children in Western Uttar Pradesh, India

2018 ◽  
Vol 5 (5) ◽  
pp. 1904
Author(s):  
Najia Hassan ◽  
Sonam Chalotra ◽  
Satinder Aneja
Keyword(s):  
Severe Malaria ◽  
Severe Disease ◽  
Tertiary Care ◽  
Case Fatality ◽  
Pediatric Intensive Care ◽  
Febrile Illness ◽  
Control Programme ◽  
Age Group ◽  
Tertiary Care Centre ◽  
Hematological Manifestations

Background: Globally, malaria is one of the important causes of mortality in pediatric age group.  We describe here the clinico-hematological manifestations of malaria in children in Western Uttar Pradesh.Methods: A Retrospective study was done over 8 months in pediatric ward and pediatric intensive care unit of a tertiary care centre in Greater Noida. Children below 18 years admitted with acute febrile illness with peripheral smear and / or rapid malaria antigen test positive were included in the study.  Detailed clinical, biochemical and hematological characteristics of children hospitalized with severe malaria were recorded and patients were managed according to National Vector Born Disease Control Programme Guidelines for malaria treatment.Results: Out of 115 children admitted with malaria, majority of cases were due to P. vivax (88.7%) compared to P. falciparum (5%) and Mixed infection (6%). Malaria was more common in males and in 1 to 5 years age group. Out of 115 patients, severe malaria was present in 27 (23.4%) patients, all infected with P. vivax. Among them, bleeding was present in 13.04 %, shock in 9.56%, acidosis in 9.56%, jaundice in 5.21%, seizures in 3.47%, severe anemia in 5.21%, renal impairment in 3.47%, impaired sensorium in 1.73% and pulmonary edema was present in 0.86% patients respectively.  Case fatality Rate was 1.73%, all due to severe vivax malaria.Conclusions: The study highlights that P. vivax is a common  cause of malaria in Western UP and can result in a severe disease with potential mortality.

scholarly journals Clinico-laboratory profile of severe Plasmodium vivax malaria in a tertiary care centre in Kolkata

2013 ◽  
Vol 3 (1) ◽  
pp. 53 ◽  
Author(s):  
Sayantan Ray ◽  
Manjari Saha ◽  
Debojyoti Sarkar ◽  
Arunansu Talukdar ◽  
Amitava Chakraborty
Keyword(s):  
Plasmodium Vivax ◽  
Vivax Malaria ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Plasmodium Vivax Malaria ◽  
Laboratory Profile

scholarly journals Comparison of Clinical Profile between P. vivax and P. falciparum Malaria in Children: A Tertiary Care Centre Perspective from India

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Jagdish Prasad Goyal ◽  
Aarti M. Makwana
Keyword(s):  
Tertiary Care ◽  
Peripheral Blood Smear ◽  
Western India ◽  
Care Centre ◽  
Inclusion Criteria ◽  
Tertiary Care Centre ◽  
Medical College ◽  
Significant Difference ◽  
Malaria Antigen ◽  
Low Incidence

Background. Malaria is a one of the leading causes of morbidity and mortality in tropical countries. Plasmodium vivax (P. vivax) is usually thought to be causing benign malaria with low incidence of complications as compared to Plasmodium falciparum (P. falciparum). Methods. This retrospective observational study included malaria patients who were admitted to K.T. Children Hospital and P.D.U. Government Medical College, Rajkot, a tertiary care teaching hospital, Gujarat, western India, during the period January 2012 to December 2012. Inclusion criteria were patients in whom either P. falciparum or P. vivax was positive on rapid malaria antigen test and peripheral blood smear. Patients showing mixed infections were excluded from study. Results. A total of 79 subjects (mean age 5.4±3.6 years) were included in the study. It consisted of 47 P. vivax and 32 P. falciparum cases. The P. vivax cases consisted of 33 (70.2%) males and 11 (19.8%) females while P. falciparum cases consisted of 14 (43.8%) males and 18 (56.2%) females. One patient of each P. vivax and P. falciparum expired. There was no statistical significant difference found between complications such as anemia, thrombocytopenia, liver and renal dysfunction, ARDS, and cerebral malaria between P. vivax and P. falciparum. Conclusion. We conclude that P. vivax monoinfection tends to have as similar course and complications as compared to malaria due to P. falciparum monoinfection.

ANAEMIA AND MALARIA: A STUDY FROM MADHYA PRADESH

2021 ◽  
pp. 74-75
Author(s):  
Parag Gupta ◽  
Lal Pranay Singh
Keyword(s):  
Falciparum Malaria ◽  
Vivax Malaria ◽  
Health Centre ◽  
Tertiary Care ◽  
P Value ◽  
Mosquito Vector ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Medical College ◽  
History Of

Background: Malaria is common despite interventions directed to mosquito vector control and treatment of symptomatic cases. In areas where malaria is hyperendemic, such as the study area, a high percentage of the population may harbor the Plasmodium parasite in their blood. The current study was planned to assess the prevalence of malaria and anemia. Methods: A total number of 150 cases were studied for a period of 2 years from Aug 2013 to Sept 2015. Haematological parameters of 150 patients, including 100 malaria-infected and 50 non-malaria infected, who were admitted at the rural tertiary care centre with history of fever were analysed. Patients who were diagnosed as malaria were included in the study. Cases were selected from the the rural health centre of Index Medical College. Results: The median of Hb in patients with falciparum malaria (11.5 g/dL) was signicantly lower than those with vivax malaria (11.9 g/dL) and nonmalaria (13.8 g/dL) groups (P value=<0.0001). Thirty Five (35%) of patients with falciparum malaria; Thirty Two (32%) of patients with vivax malaria; and Thirteen (26%) of patients with non-malaria groups had anaemia. Conclusion: Malaria is common in patients of anaemia. The prevalence of both are positively correlated and both are associated with increased morbidi

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