scholarly journals Clinico-hematological manifestations of malaria in children in Western Uttar Pradesh, India

2018 ◽  
Vol 5 (5) ◽  
pp. 1904
Author(s):  
Najia Hassan ◽  
Sonam Chalotra ◽  
Satinder Aneja
Keyword(s):  
Severe Malaria ◽  
Severe Disease ◽  
Tertiary Care ◽  
Case Fatality ◽  
Pediatric Intensive Care ◽  
Febrile Illness ◽  
Control Programme ◽  
Age Group ◽  
Tertiary Care Centre ◽  
Hematological Manifestations

Background: Globally, malaria is one of the important causes of mortality in pediatric age group.  We describe here the clinico-hematological manifestations of malaria in children in Western Uttar Pradesh.Methods: A Retrospective study was done over 8 months in pediatric ward and pediatric intensive care unit of a tertiary care centre in Greater Noida. Children below 18 years admitted with acute febrile illness with peripheral smear and / or rapid malaria antigen test positive were included in the study.  Detailed clinical, biochemical and hematological characteristics of children hospitalized with severe malaria were recorded and patients were managed according to National Vector Born Disease Control Programme Guidelines for malaria treatment.Results: Out of 115 children admitted with malaria, majority of cases were due to P. vivax (88.7%) compared to P. falciparum (5%) and Mixed infection (6%). Malaria was more common in males and in 1 to 5 years age group. Out of 115 patients, severe malaria was present in 27 (23.4%) patients, all infected with P. vivax. Among them, bleeding was present in 13.04 %, shock in 9.56%, acidosis in 9.56%, jaundice in 5.21%, seizures in 3.47%, severe anemia in 5.21%, renal impairment in 3.47%, impaired sensorium in 1.73% and pulmonary edema was present in 0.86% patients respectively.  Case fatality Rate was 1.73%, all due to severe vivax malaria.Conclusions: The study highlights that P. vivax is a common  cause of malaria in Western UP and can result in a severe disease with potential mortality.

scholarly journals Study of malaria and associated co-morbidity in children admitted with fever manifestation in a tertiary care centre

2020 ◽  
Vol 7 (8) ◽  
pp. 1705
Author(s):  
Pawan Ghanghoriya ◽  
Rahul Borkar ◽  
Monica Lazarus ◽  
Manish Ajmariya
Keyword(s):  
Severe Malaria ◽  
Severe Acute Malnutrition ◽  
Care Center ◽  
Tertiary Care ◽  
Febrile Illness ◽  
Acute Malnutrition ◽  
Age Group ◽  
Tertiary Care Centre ◽  
Medical College ◽  
Co Morbidity

Background: Children under five year of age are highly vulnerable to malaria infection and often face dire consequences such as severe malaria if they are not promptly and adequately treated with anti-malarial medications. Authors set out to evaluate malaria and associated co-morbidity among children admitted with febrile illness in tertiary care center NSCB Medical college Jabalpur, India.Methods: This prospective and analytic study focused on children admitted with fever in pediatric unit of N.S.C.B. Medical College, Jabalpur, Madhya Pradesh, India. If any co-morbidity present with malaria their manifestation was noted. Association of co-morbidity with malaria was done, and effect of co-morbidity on severity of malaria and outcome of patients was noted.Results: A total number of 1950 of children suspected to have malaria who were tested by RDT and microscopy (PSMP), out of them 100 children were positive. Mean age calculated was 7.3±4.3 years. Maximum number of severe malaria cases (40.6%) were found in 6 months to <5 years age group. Most common co-morbidity associated with malaria was anemia (53%) followed by pneumonia (36%) hepatitis (26%), diarrhea (24%), enteric fever (15%), septicemia and meningoencephalitis (10%) each, UTI (4%), and AKI (6%), while dengue (3%) and severe acute malnutrition (2%). Out of 69 cases of severe malaria 46.3% cases had two and 34.7% cases had more than two co-morbidities while in 31 cases of uncomplicated malaria 38.7% cases had two co-morbidity and only 3% had more than two co-morbidity.Conclusions: All RDT positive cases have associated co-morbidity with malaria in our study, more is the co-morbidity is longer were the duration of stay and higher the complications and even mortality. 

scholarly journals Incidence of hypertensive disorders of pregnancy and it’s maternal-fetal outcome in admitted antenatal patients in tertiary care centre, Bhilai, Chhattisgarh, India

2021 ◽  
Vol 10 (4) ◽  
pp. 1561
Author(s):  
Pooja Singh ◽  
Seema Khandasu ◽  
Rekha Ratnani
Keyword(s):  
Severe Disease ◽  
Tertiary Care ◽  
Medical Science ◽  
Case Fatality ◽  
Fetal Mortality ◽  
Medical Complication ◽  
Hypertensive Disorder ◽  
Hypertensive Disorders Of Pregnancy ◽  
Tertiary Care Centre ◽  
Hypertensive Disorders

Background: Pre-eclampsia refers to any new onset of hypertension and proteinuria after 20 weeks of gestation in a previously normotensive, non proteinuric women. Hypertension is a very common medical complication of pregnancy. It is one of the leading causes of maternal and fetal mortality and morbidity worldwide. Early detection, close surveillance and timely delivery are necessary to reduce complications and improvement in maternal and fetal health and outcome. To determine the incidence, risk factors and maternal and fetal outcomes in women with hypertensive disorders of pregnancy in all pregnant women attending Obstetrics and Gynaecology department, Shanakaracharya Institute of Medical Science, Bhilai.Methods: This is a retrospective record-based observational study conducted over a period of one year from January 2020-December 2020 after getting approval from the institutional ethical committee. Patients diagnosed with hypertensive disorders of pregnancy were evaluated and data was collected and analyzed.Results: Of the 1503 deliveries in the hospital during the period under review, 131(8.7%) were managed for hypertensive disorders of pregnancy. Pre-eclampsia was the commonest type of hypertensive disorder of pregnancy (69.3%) with the majority presenting with severe disease. Women of all age group were affected with highest incidence among 21-30years of age (69.4%). The incidence was maximum among primigravida (67.2%) compared to multipara 100 (32.8%). Intra uterine deaths were recorded among 12.2%, while a major share of fetus (41.2%) were diagnosed to have intrauterine growth retardation. Most common maternal complication in our study was abruption (7.6%), followed by HELLP (2.2%). Two maternal deaths were recorded, giving a case fatality rate of 1.5%.Conclusions: Hypertensive disorders of pregnancy are associated with high maternal and fetal morbidity and mortality. Regular antenatal follow up will help in early diagnosis and timely intervention of the cases. Also, special consideration and close surveillance of those women with early-onset disease is important. There is need for strengthening of communication and referral systems in the healthcare.

scholarly journals Severe vivax malaria trends in the last two years: a study from a tertiary care centre, Delhi, India

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Monika Matlani ◽  
Loick P. Kojom ◽  
Neelangi Mishra ◽  
Vinita Dogra ◽  
Vineeta Singh
Keyword(s):  
Severe Malaria ◽  
Disease Severity ◽  
Vivax Malaria ◽  
Severe Disease ◽  
Tertiary Care ◽  
Peripheral Blood Smear ◽  
Severe Anaemia ◽  
Significant Shift ◽  
Care Centre ◽  
Tertiary Care Centre

Abstract Background Plasmodium vivax, once considered benign species, is recently being recognised to be causing severe malaria like Plasmodium falciparum. In the present study, the authors report the trends in malaria severity in P. vivax among patients from a Delhi government hospital. The aim of the study was to understand the disease severity and the burden of severe vivax malaria. Methods A hospital based study was carried out from June 2017 to December 2018 at a tertiary care centre from Delhi, India. Patients were tested for malaria using peripheral blood smear (PBS) and/or rapid malaria antigen test (RMAT). The severe and non-severe vivax malaria categorization was done as per the WHO guidelines. Sociodemographic, clinic and paraclinical data were collected from patients and their medical records. Results Of the 205 patients, 177 (86.3%) had P. vivax infection, 22 (10.7%) had P. falciparum infection and six (2.9%) had mixed infection with both the species. Out of 177 P. vivax cases included in this study one or more manifestations of severe malaria was found in 58 cases (32.7%). Severe anaemia (56.9%), jaundice (15%) and significant bleeding (15%) were the most common complications reported in most of patients, along with thrombocytopenia. Conclusions In this study, it is evident that vivax malaria is emerging as the new severe disease in malaria patients, a significant shift in the paradigm of P. vivax pathogenesis. The spectrum of complications and alterations in the laboratory parameters in P. vivax clinical cases also indicate the recent shift in the disease severity.

scholarly journals Trends in Acute Undifferentiated Febrile Illness in Patients Seeking Treatment from a Tertiary Care Hospital of Central Kerala

2021 ◽  
Vol 8 (18) ◽  
pp. 1230-1235
Author(s):  
Reshmi Ramachandran ◽  
Jeena Ramesh ◽  
Bindhu Vasudevan
Keyword(s):  
Public Health ◽  
Disease Incidence ◽  
Tertiary Care ◽  
Age Groups ◽  
Case Fatality ◽  
Febrile Illness ◽  
Sampling Technique ◽  
P Value ◽  
Care Hospital ◽  
Age Group

BACKGROUND Acute undifferentiated febrile illness (AUFI / AFI) is one of the most common reasons for people seeking medical care globally. Investigation into the aetiology and trends in AUFI cases are valuable public health data source. Absence of such evidence-based data may result in unintended public health consequences. Present study was undertaken to address the gap in period specific trends in AUFI cases reported from the region. METHODS A record based descriptive study was done in patients treated with AUFI from January 1st, 2015 to December 31st , 2019 in Government Medical College, Ernakulam. Universal sampling technique was adopted, and the data was entered in Microsoft Excel and analysed using Epi-Info software. Line diagram was constructed to obtain the trends in AUFI cases over the five-year period. Chisquare test was applied to find out the association between age group (paediatric and others) and causative agents of AUFI. RESULTS A total of 7998 AUFI cases were included in this study. Highest number of AUFI cases (1986) was reported in the year 2017. Under five age group was the most common, 1564 (19.6 %). Majority of the AUFI were reported among males, 4947 (61.9 %). Undetermined fever was found to be the most common AUFI, 2188 (27.4 %). Dengue fever, 1993 (24.9 %) was the most diagnosed AUFI. Viral aetiology was found to be the most common, 3895 (48.7 %) in both paediatric and other age groups. No statistically significant association was found between (P-value = 0.22) age group and organisms causing AUFI. There were 121 (1.5 %) deaths reported among the AUFI cases during the five-year period. It was seen that the case fatality due to AUFI was highest (2.41 %) in the year 2019. CONCLUSIONS A lack of consistent pattern in the aetiology of AUFI cases reported over the fiveyear study period, calls for persistent vigil by the public health surveillance system in the region, to identify any impending infectious disease outbreak at the earliest. As this study is based on hospital-based surveillance record it can underestimate the disease incidence. KEYWORDS Acute Undifferentiated Febrile Illness (AUFI), Trends, Dengue, Acute Febrile Illness

Predictors of Severity of Scrub Typhus in Children Requiring Pediatric Intensive Care Admission

2021 ◽  
Author(s):  
Arpita Khemka ◽  
Mihir Sarkar ◽  
Ankika Basu ◽  
Partha Pratim Dey ◽  
Satyabrata Roy Chowdhoury ◽  
...  
Keyword(s):  
Intensive Care ◽  
Urine Output ◽  
Scrub Typhus ◽  
Tertiary Care ◽  
Case Fatality ◽  
Pediatric Intensive Care ◽  
Age Group ◽  
Intensive Care Admission ◽  
Altered Sensorium ◽  
Number Of Patients

AbstractObjective of our study was to determine the clinical characteristics and laboratory profile of scrub typhus patients requiring pediatric intensive care admission and to find out risk factors for the severity of illness. This was a cross-sectional observational study conducted on 1-month to 12-year-old children admitted with scrub typhus in a tertiary care pediatric intensive care unit (PICU). Relevant demographic, clinical, laboratory, treatment, and outcome-related data were documented. The severity of the disease was measured in the form of multiple organ dysfunction syndrome (MODS). With further correlation, and univariate and multivariate analyses, factors associated with severe disease were identified. During the study period, out of 586 PICU admission, 62 patients (10.6%) were diagnosed with scrub typhus. The mean age was 63.85 ± 52.78 months, where infants constituted 32.3% of the total population. Fever was present in 100% of the cases. Common indications of PICU admission were: respiratory distress 42 (67.7%), altered sensorium 41 (66.1%), convulsion 37 (59.7%), and shock 31 (50%). Total number of patients with MODS was 40 (64.5%). The case fatality rate was 8%. On multivariate analysis, infant age group (p = 0.02), altered sensorium (p = 0.001), reduced urine output (p = 0.02), thrombocytopenia (p = 0.001), raised C-reactive protein (p = 0.004), hyponatremia (p = 0.005), hypoalbuminemia (p = 0.01), deranged international normalized ratio (p = 0.02), and hyperferritinemia (p = 0.02) came out to be independent factors in predictability for development of MODS. Multiorgan dysfunction is a life-threatening manifestation of scrub typus in children, which necessitates PICU admission. Infant age group, presence of altered sensorium, reduced urine output, thrombocytopenia, elevated inflammatory markers, coagulopathy, hypoalbuminemia, and hyponatremia predict risk for MODS.

scholarly journals Peripartum hysterectomy: a five year review at a tertiary care centre

2017 ◽  
Vol 6 (8) ◽  
pp. 3590
Author(s):  
Deepak A. V. ◽  
K. J. Jacob ◽  
Sumi P. Maria
Keyword(s):  
Tertiary Care ◽  
Case Series ◽  
Case Fatality ◽  
Tertiary Care Centre ◽  
Retrospective Case ◽  
College Hospital ◽  
Peripartum Hysterectomy ◽  
Medical College ◽  
Obstetric Haemorrhage ◽  
Suboptimal Care

Background: Peripartum hysterectomy is a life-saving procedure resorted to when conservative measures fail to control obstetric haemorrhage. Several predisposing factors, suboptimal care and lack of infrastructure may lead to this emergency procedure. We wanted to find out factors associated with peripartum hysterectomy and the adverse maternal outcomes at our centre.Methods: A retrospective case series analysis of 40 cases of peripartum hysterectomy performed over a period of 5 years from January 2010 to December 2014 at Government Medical College Hospital, Thrissur, Kerala was done.Results: The incidence of peripartum hysterectomy was 0.29%. The most common indication for peripartum hysterectomy was hysterectomy was uterine atony (50%). Thirty-five women (88%) were between 20 and 35 years. Most of the subjects were unbooked. There were two maternal deaths (case fatality rate of 5%) following peripartum hysterectomy during this period. All the subjects required blood transfusion.Conclusions: Prompt performance hysterectomy before the patient’s clinical condition deteriorates is the key to success. The incidence of adherent placenta is increasing, so every effort should be taken to reduce the caesarean section rates globally. 

scholarly journals Detection and Enumeration of the Commonest Stool Parasites Seen in a Tertiary Care Center in South India

2013 ◽  
Vol 2013 ◽  
pp. 1-6
Author(s):  
Vani Chandrashekar
Keyword(s):  
Entamoeba Histolytica ◽  
South India ◽  
Care Center ◽  
Tertiary Care ◽  
Age Group ◽  
Tertiary Care Center ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Stool Samples

The aim of this study was to identify common stool parasites in patients attending a tertiary care centre in South India. We evaluated 2355 stool samples and parasites were detected in 7.9% of samples. 41.1% of our patients were in the 45–58-year age group. Protozoal infections were the commonest seen in 7.8% of samples. Entamoeba histolytica was the commonest protozoa (4.6%) followed by Entamoeba coli (1.2%) and Giardia (0.8%). Entamoeba histolytica and Entamoeba coli were together seen in 0.63%, and they were the commonest organisms seen in samples with multiple-organism infection. Both were equally detected in diarrheal samples.

scholarly journals Pattern of Ear Diseases among Paediatric ENT Patient: An Experience from Tertiary Care Centre, Pokhara, Nepal

2012 ◽  
Vol 32 (2) ◽  
pp. 142-145 ◽  
Author(s):  
B Sigdel ◽  
R Nepali
Keyword(s):  
Tertiary Care ◽  
Age Group ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Suppurative Otitis Media ◽  
Ear Diseases ◽  
Paediatric Age ◽  
One Year ◽  
A Prospective Study ◽  
Nose And Throat

Introduction: Ear diseases are common in children mainly due to altered anatomy of Eustachian tube which is straighter in children as compared to that in adults. However, the cause of hearing loss in children is more varied, including the etiologies. This study was done to find out the pattern of ear diseases in paediatric age group attending ear, nose and throat OPD in a tertiary care centre in Pokhara, Nepal. Materials and Methods: This is a prospective study done in paediatric patients attending ENT OPD over a period of one year from January 2010 to January 2011. The diagnoses were made on the basis of history and clinical examination. Results were expressed in numbers and percentages. Results: Out of 1632 Pediatric ENT patients, 944 had ear diseases, 59.2% were males and 40.8% females. Wax (33.4%) was the commonest diagnosis followed by Chronic suppurative otitis media (24.3%) and Acute ottitis media (13%). Conclusion: Ear diseases are most common condition in ENT OPD among paediatric age group. Wax, CSOM and ASOM were the three most common ear diseases. J. Nepal Paediatr. Soc. 32(2) 2012 142-145 doi: http://dx.doi.org/10.3126/jnps.v32i2.5673

TO DETERMINE THE PREVALENCE AND OCCURANCE OF VISUAL MORBIDITY IN PATIENTS OF PTERYGIUM ATTENDING EYE OPD IN A TERTIARY CARE CENTRE OF EASTERN INDIA

2021 ◽  
pp. 80-81
Author(s):  
Vandana Parasar ◽  
Vidyabhushan Kumar ◽  
Ankita Singh ◽  
Nilesh Mohan
Keyword(s):  
Socioeconomic Status ◽  
Tertiary Care ◽  
Living Condition ◽  
Age Group ◽  
Care Centre ◽  
Eastern India ◽  
Tertiary Care Centre ◽  
Male Preponderance ◽  
Uvb Exposure ◽  
Epidemiological Trends

To determine the prevalence and occurrence of visual morbidity in patients of pterygium attending eye opd in a tertiary care centre of Bihar. Methods: In this observational study a total of 193 patients, diagnosed with pterygium, underwent complete ocular examination by an ophthalmologist. Epidemiological trends including age, sex, occupation, effect of living condition and socioeconomic status were analyzed. Results: There is a male preponderance of 58.03%. The age incidence of the group showed that the incidence of pterygium was 10.36% in the age group of less than 30 years. It rises to a maximum of 29.53% in the age of 41-50 years and then gradually declines.. The incidence was found to be maximum among farmers(39.86%) followed by miners(31%). Conclusion: People who work outdoors are at a greater risk because they are subjected to involuntary UVB exposure. The highest exposure occurs during the two hours on either side of noon. Workers must be aware and should take appropriate measures like wearing protective glasses, caps, etc

A CLINICOEPIDEMIOLOGICAL STUDY ON PAEDERUS DERMATITIS IN A TERTIARY CARE CENTRE, CHENNAI

2021 ◽  
pp. 25-27
Author(s):  
P. Mohan ◽  
P. Revathi Guru ◽  
V. Sudha ◽  
L. Balamurugan ◽  
Pavithra Gunasekaran ◽  
...  
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Sudden Onset ◽  
The Body ◽  
Care Hospital ◽  
Age Group ◽  
Common Condition ◽  
Tertiary Care Centre ◽  
Linear Lesions ◽  
Paederus Dermatitis

Paederus dermatitis is a form of irritant contact dermatitis due to contact with certain insects of the genus Paederus presenting with mostly erythematous linear lesions of sudden onset on exposed parts of the body. To study the clinico epi Aim: demiological features in patients with Paederus dermatitis. A retrospective analysis of clinicoepidemiological Materials & Methods: features of patients affected with Paederus dermatitis who had attended the Dermatology OPD, in a tertiary care hospital between January 2018 to December 2019 was done. All the required data had been collected from the OPD records and details were tabulated and analysed. A total of 56 patients had been affected with Result: Paederus dermatitis during the study period, of which 32 were males and 24 were females. 41out of 56 (73.21%) of patients presented between the months of August and December. Most common age group affected were between 11 to 30 yrs, with front and back of neck being the most common affected sites. In 42 out of the 56 patients the lesions resolved with post inammatory hyperpigmentation. Conclusion: Paederus dermatitis is a common condition that is often misdiagnosed and hence awareness is required for the clinicians and the general public to prevent it.

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