scholarly journals Serum retinol binding protein 4 is negatively related to estrogen in Chinese women with obesity: a cross-sectional study

2016 ◽  
Vol 15 (1) ◽  
Author(s):  
Qian Li ◽  
Weiyun Wu ◽  
Huandong Lin ◽  
Xinxia Chang ◽  
Hua Bian ◽  
...  
Keyword(s):  
Chinese Women ◽  
Binding Protein ◽  
Cross Sectional Study ◽  
Retinol Binding Protein ◽  
Sectional Study ◽  
Serum Retinol ◽  
Cross Sectional ◽  
Retinol Binding Protein 4

scholarly journals Association Between Retinol-binding Protein and Sarcopenia in General Inpatient Older Adults: a Cross Sectional Study

2021 ◽  
Author(s):  
Kai Liu ◽  
Ying Chen ◽  
Tao Liu ◽  
Kun Zhang ◽  
Yunqian Li ◽  
...  
Keyword(s):  
Binding Protein ◽  
Multivariate Logistic Regression Analysis ◽  
Cross Sectional Study ◽  
Hospitalized Patients ◽  
Retinol Binding Protein ◽  
Sectional Study ◽  
Serum Retinol ◽  
Cross Sectional ◽  
Total Prevalence ◽  
Increased Risk

Abstract Objective: This study aims to evaluate the relationship between serum retinol binding protein levels and sarcopenia in elderly general hospitalized patients. Methods: This cross-sectional study included 682 elderly patients with Barthel-index ≥100 on admission. Sarcopenia was defined according to the recently updated Asian Sarcopenia Working Group 2019 criteria. The skeletal muscle mass index was measured by dual-energy X-ray absorptiometry. Serum prealbumin, albumin, hemoglobin, blood creatinine, alanine aminotransferase, aspartate aminotransferase, and retinol binding protein are also detected. Multivariate logistic regression analysis was used to evaluate the association between serum RBP levels and sarcopenia, and to adjust for potential confounding factors.Results:There are 105 cases of sarcopenia, 56 males and 49 females. The total prevalence of sarcopenia is 15.40% in general inpatients, of which 16.47% are males and 14.33% are females.For men and women, it was observed that the serum retinol binding protein in sarcopenia patients was significantly lower than that without sarcopenia (24.43±8.12 vs 29.98±9.91, P<0.001) and(23.27±5.13 vs 28.35±6.63, P < 0.001),The fully adjusted model showed that male and female low retinol binding protein participants had a 2.341(1.176,4.660) and 2.911(1.324-6.400) times higher risk of sarcopenia than normal retinol binding protein respectively.Conclusion: Low levels of retinol binding protein are associated with an increased risk of sarcopenia in elderly general hospitalized patients.

scholarly journals Serum levels of retinol binding protein 4 in women with different levels of adiposity and glucose tolerance

2014 ◽  
Vol 58 (7) ◽  
pp. 709-714 ◽  
Author(s):  
Eleonora Beltrame Comucci ◽  
Ana Carolina Junqueira Vasques ◽  
Bruno Geloneze ◽  
Antonio Ramos Calixto ◽  
José Carlos Pareja ◽  
...  
Keyword(s):  
Glucose Tolerance ◽  
Glycated Hemoglobin ◽  
Binding Protein ◽  
Serum Levels ◽  
Normal Glucose Tolerance ◽  
Cross Sectional Study ◽  
Retinol Binding Protein ◽  
Cross Sectional ◽  
Retinol Binding Protein 4 ◽  
Wide Range

Objective Retinol-binding protein 4 (RBP4) is an adipokine responsible for vitamin A (retinol) transportation. Studies associated RBP4 increased levels with severity of type 2 diabetes mellitus (T2DM) and insulin resistance (IR). The study aimed to quantify RBP4 serum standards in women with a wide range of body mass index (BMI) and glucose tolerance level. Subjects and methods: Cross-sectional study was performed with 139 women divided into three groups: Group 1 (lean-control, n = 45) and Group 2 (obese, n = 53) with normal glucose tolerance and group 3 (obese with T2DM, n = 41), called G1, G2 and G3. Were assessed clinical, biochemical, anthropometric and body composition parameters. Results According to data analysis, we obtained in G1 higher RBP4 levels (104.8 ± 76.8 ng/mL) when compared to G2 (87.9 ± 38 ng/mL) and G3 (72.2 ± 15.6 ng/mL) levels. Also, were found: in G1 positive correlations of RBP4 with BMI (r = 0.253), glycated hemoglobin (r = 0.378) and fasting insulin (r = 0.336); in G2 with glycated hemoglobin (r = 0.489); in G3 with glycated hemoglobin (r = 0.330), fasting glucose (r = 0.463), HOMA-IR (r = 0.481). Conclusions Although RBP4 have shown lower levels in diabetic and obese, a strong correlation with HOMA-IR index highlights that, in our study, there is growing IR when there is an increasing in RBP4 levels.

scholarly journals Relationship between childhood secondhand smoke exposure and the occurrence of hyperlipidaemia and coronary heart disease among Chinese non-smoking women: a cross-sectional study

BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e048590
Author(s):  
Kewei Wang ◽  
Yuanqi Wang ◽  
Ruxing Zhao ◽  
Lei Gong ◽  
Lingshu Wang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Secondhand Smoke ◽  
Chinese Women ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Shs Exposure

ObjectiveThe objective of this study was to evaluate the influence of secondhand smoke (SHS) exposure during childhood on type 2 diabetes mellitus, hypertension, hyperlipidaemia and coronary heart disease among Chinese non-smoking women.MethodsIn this cross-sectional study, the SHS exposure data in childhood were obtained using a questionnaire survey. Self-reported childhood SHS exposure was defined as the presence of at least one parent who smoked during childhood.ResultsOf the 6522 eligible participants, 2120 Chinese women who had never smoked were assessed. The prevalence of SHS exposure in the entire population was 28.1% (596). SHS exposure during childhood was not significant for the standard risk factors of type 2 diabetes mellitus (p=0.628) and hypertension (p=0.691). However, SHS was positively associated with hyperlipidaemia (p=0.037) after adjusting for age, obesity, education status, physical activity, alcohol consumption, current SHS exposure status, diabetes mellitus and hypertension. In addition, childhood SHS increased the occurrence of coronary heart disease (p=0.045) among non-smokers after further adjusting for hyperlipidaemia.ConclusionSHS exposure during childhood is associated with prevalent hyperlipidaemia and coronary heart disease in adulthood among non-smoking Chinese women.

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