scholarly journals Oligomannuronate prevents mitochondrial dysfunction induced by IAPP in RINm5F islet cells by inhibition of JNK activation and cell apoptosis

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Xi Liu ◽  
Qiong Li ◽  
Xiaolei Cheng ◽  
Zhichun Liu ◽  
Xiaoliang Zhao ◽  
...  
Keyword(s):  
Mitochondrial Dysfunction ◽  
Cell Apoptosis ◽  
Islet Cells ◽  
Jnk Activation

scholarly journals HDAC inhibitor, scriptaid, induces glioma cell apoptosis through JNK activation and inhibits telomerase activity

2009 ◽  
Vol 14 (8) ◽  
pp. 2151-2161 ◽  
Author(s):  
Vivek Sharma ◽  
Nitin Koul ◽  
Christy Joseph ◽  
Deobrat Dixit ◽  
Sadashib Ghosh ◽  
...  
Keyword(s):  
Hdac Inhibitor ◽  
Cell Apoptosis ◽  
Glioma Cell ◽  
Telomerase Activity ◽  
Jnk Activation

scholarly journals Glucose and Fatty Acids Synergize to Promote B-Cell Apoptosis through Activation of Glycogen Synthase Kinase 3β Independent of JNK Activation

PLoS ONE ◽  
2011 ◽  
Vol 6 (4) ◽  
pp. e18146 ◽  
Author(s):  
Katsuya Tanabe ◽  
Yang Liu ◽  
Syed D. Hasan ◽  
Sara C. Martinez ◽  
Corentin Cras-Méneur ◽  
...  
Keyword(s):  
Fatty Acids ◽  
B Cell ◽  
Cell Apoptosis ◽  
Glycogen Synthase ◽  
Glycogen Synthase Kinase ◽  
Glycogen Synthase Kinase 3Β ◽  
Jnk Activation

Liensinine perchlorate inhibits colorectal cancer tumorigenesis by inducing mitochondrial dysfunction and apoptosis

2018 ◽  
Vol 9 (11) ◽  
pp. 5536-5546 ◽  
Author(s):  
Yang Wang ◽  
Yang-Jia Li ◽  
Xiao-Hui Huang ◽  
Can-Can Zheng ◽  
Xing-Feng Yin ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Mitochondrial Dysfunction ◽  
Signaling Pathway ◽  
Cancer Cell ◽  
Cell Apoptosis ◽  
Quantitative Proteomics ◽  
Food Source ◽  
Colorectal Cancer Cell ◽  
Functional Screen ◽  
Cancer Cell Apoptosis

Functional screen and quantitative proteomics reveal that food-source liensinine induces colorectal cancer cell apoptosisviathe JNK-mitochondrial dysfunction signaling pathway.

Mitochondrial Dysfunction Contributes to Germ Cell Apoptosis via the JNK/p53/ survivin Pathway

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
May Al-Maghrebi ◽  
Fatemah Fadel ◽  
Nora Al-Kandari ◽  
Farah Khashab ◽  
Farah Al-Saleh
Keyword(s):  
Germ Cell ◽  
Mitochondrial Dysfunction ◽  
Cell Apoptosis ◽  
Germ Cell Apoptosis

Overexpression of ankyrin repeat domain 1 enhances cardiomyocyte apoptosis by promoting p53 activation and mitochondrial dysfunction in rodents

2015 ◽  
Vol 128 (10) ◽  
pp. 665-678 ◽  
Author(s):  
Liang Shen ◽  
Ci Chen ◽  
Xuan Wei ◽  
Xixian Li ◽  
Guangjin Luo ◽  
...  
Keyword(s):  
Heart Failure ◽  
Angiotensin Ii ◽  
Mitochondrial Dysfunction ◽  
Cell Apoptosis ◽  
Pressure Overload ◽  
Ankyrin Repeat ◽  
Cardiomyocyte Apoptosis ◽  
Repeat Domain ◽  
Ankyrin Repeat Domain ◽  
P53 Activation

This study demonstrated that myocardial overexpression of Ankrd1/CARP promotes angiotensin-II- and pressure-overload-induced cell apoptosis and heart failure, with these deleterious effects being at least partly mediated by the accumulation of p53 and mitochondrial dysfunction.

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