Patient Engagement and Patient-Centred Care in the Management of Advanced Chronic Kidney Disease and Chronic Kidney Failure

Chronic Kidney Failure describes as the gradual loss of kidney functionand it is irreversible, to replace the loss of kidney function a therapy tokidney function is needed, which is hemodialysis. The objective of thisresearch is to know the levels of ureu and creatinine serum for prehemodialysis and post hemodialysis at RSU Royal Prima Medan. Themethods that are being used for this research is descriptive with 54 patientsas samples. The results of this research is loss of urea and creatinine serumlevel, with the average of urea level for pre hemodialysis is 128.11 mg/dL,and the average of urea level for post hemodialysis is 43.26 mg/dL with1,8% patient with low urea level, 50% with normal urea level, and 48.2%with high urea level. The average of creatine level for pre hemodialysis is11.56 mg/dL, and the average of creatine levels is 4.3 mg/dL, with all of thepatient still have a high creatinine levels. The conclusion is there is drop forboth urea and creatinen serum level, but the urea level for half of the patientdid not go down to normal, and for the creatinine level there is none of thepatient creatinine level that go down to normal.

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EFEKTIFITAS MENGUNYAH PERMEN KARET TERHADAP XEROSTOMIA PADA PASIEN CHRONIC KIDNEY DISEASE YANG MENJALANI HEMODIALISA DI RUMAH SAKIT AWAL BROS BATAM TAHUN 2019

Ners Journal ◽

10.52999/nersjournal.v1i2.68 ◽

2021 ◽

Vol 1 (2) ◽

Author(s):

PUTRI

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Kidney Failure ◽

Chronic Kidney Failure ◽

World Health ◽

Uncontrolled Hypertension ◽

Chewing Gum ◽

Electrolyte Balance ◽

Waste Products ◽

Number Of Patients

Chronic kidney failure or chronic kidney disease is a progressive deviation, kidney function that can not recover, where the body's ability to maintain metabolic balance, fluid and electrolytes, resulting in uremia. This condition is caused by chronic glomerulonephritis, pyelonephritis, uncontrolled hypertension, hereditary lesions, vascular abnormalities, urinary tract obstruction, diabetes, and infections. Today, chronic kidney disease is a disease whose prevalence continues to increase. World Health Organization (WHO) released data on growth in the number of patients with chronic kidney failure in 2013 increased by 50% from the previous year and in America the incidence of chronic kidney failure increased by 50% in 2014 and every year 200,000 Americans undergo hemodialysis Hemodialysis is one way to remove metabolic waste products in the form of a solution and water that is in the blood through a semipermeable membrane or called a dialyzer. The working principle of fluid transfer in hemodialysis is diffusion, osmosis, ultrafiltration and convection. Changes in fluid and electrolyte balance in Chronic Kidney Failure patients result in changes in salivary composition and flow (Fan, Zhang, Luo, Niu & Gu, 2013). In addition to changes in salivary composition and flow, patients with chronic renal failure also experience changes in dry mouth (xerostomia) due to increased ureum concentrations in the blood (Fan et al., 2013). Chewing Gum Xylitol is a candy that no artificial sweeteners activity of chewing gum, low-sugar two eggs approximately 10 minutes to 3x / day for 2 weeks would lead to mechanical stimulation and chemical that can move reflex saliva to stimulate the receptor that is monitored by the trigeminal nerve (V) and facial nerve (VII) as a taste. Sympathetic nerve stimulation will accelerate the secretion of all salivary glands in large quantities which can reduce the sensation of thirst that appears . From the results of research using the method of comparison in get , look the frequency of xerostomia before the intervention mostly dominated by xerostomia weight of 67% and the visible frequency of xerostomia after intervention largely dominated by xerostomia mild 67% , Based on the output "Test Statistics" in table 4.4 above, known p-value is 0,000. Because the value of 0.003 is smaller than <0.05, it can be concluded that "H0 is rejected", or in other words there is "Effectiveness of Chewing Gum Against Xerostomia in Chronic Kidney Disease Patients Who Underwent Hemodialysis at Batam Bros Initial Hospital in 2020

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P1835PREDICTION OF CHRONIC OF KIDNEY FAILURE BASED ON ARTIFICIAL INTELLIGENCE SYSTEM USING THE FUZZY DECISION TREE ALGORITHM

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfaa142.p1835 ◽

2020 ◽

Vol 35 (Supplement_3) ◽

Author(s):

Rifaldy Fajar ◽

Prihantini Jupri

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Decision Tree ◽

Kidney Failure ◽

Laboratory Tests ◽

Chronic Kidney Failure ◽

Decision Tree Algorithm ◽

Fuzzy Decision ◽

Fuzzy Decision Tree ◽

Tree Algorithm

Abstract Background and Aims Chronic kidney disease is one type of disease that can cause death. Until now, chronic kidney failure has no antidote, so this disease cannot be cured but can be slowed down or stopped its development. Early diagnosis of this disease will help to prevent these fatal consequences. To diagnose this disease, several laboratory tests are needed in which the results of these tests will be calculated and concluded the results by a doctor or medical practitioner. The development of science and technology, especially in the field of computers will help the work of doctors to analyze the results of laboratory tests become easier and faster. In this study, a prediction attempt is made using the Fuzzy Decision Tree classification algorithm, which is expected to obtain high accuracy results. Method This study uses the Chronic Kidney Disease (CKD) dataset taken from the UCI Machine Learning Repository. Data was collected from the hospital for approximately two months. This dataset covers a total of 400 samples with numerical attributes totaling 11 columns and nominal totaling 14 columns. Data samples were provided as many as 400 rows with 250 samples being the ckd group (positive for chronic kidney failure) and 150 samples for the notckd group (chronic kidney failure). But after going through the preprocessing stage, data that can be used amounted to 158 rows with 43 samples are the ckd group (positive chronic kidney failure) and 115 samples of the notckd group (negative chronic kidney failure). Results The trial was conducted using several predetermined thresholds and the most optimal accuracy was 98.3%, which showed a fairly high degree of accuracy. Conclusion Thus, it can be concluded that the Fuzzy Decision Tree algorithm can be said to be able to predict chronic kidney failure with a very good results.

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Influence of acute and chronic kidney failure in rats on the disposition and pharmacokinetics of ZYAN1, a novel prolyl hydroxylase inhibitor, for the treatment of chronic kidney disease-induced anemia

Xenobiotica ◽

10.1080/00498254.2016.1278287 ◽

2017 ◽

Vol 48 (1) ◽

pp. 37-44 ◽

Cited By ~ 4

Author(s):

Harilal Patel ◽

Amit Arvind Joharapurkar ◽

Vrajesh Bhaskarbhai Pandya ◽

Vishal Jagjivanbhai Patel ◽

Samadhan Govind Kshirsagar ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Kidney Failure ◽

Chronic Kidney Failure ◽

Prolyl Hydroxylase ◽

Prolyl Hydroxylase Inhibitor

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Individual patient variability with the application of the kidney failure risk equation in advanced chronic kidney disease

PLoS ONE ◽

10.1371/journal.pone.0198456 ◽

2018 ◽

Vol 13 (6) ◽

pp. e0198456 ◽

Cited By ~ 2

Author(s):

Christopher McCudden ◽

Ayub Akbari ◽

Christine A. White ◽

Mohan Biyani ◽

Swapnil Hiremath ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Kidney Failure ◽

Advanced Chronic Kidney Disease ◽

Risk Equation ◽

Failure Risk

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RELATIONSHIP BETWEEN TREATMENT ADHERENCE AND PROGRESSION OF DIABETIC NEPHROPATHY

Jurnal Muara Sains, Teknologi, Kedokteran dan Ilmu Kesehatan ◽

10.24912/jmstkik.v5i1.7991 ◽

2021 ◽

Vol 5 (1) ◽

pp. 65

Author(s):

Jimmy Chua ◽

Yohanes Firmansyah ◽

William Gilbert Satyanegara ◽

Alexander Halim Santoso ◽

Ernawati Su

Keyword(s):

Chronic Kidney Disease ◽

Diabetic Nephropathy ◽

Kidney Disease ◽

Kidney Failure ◽

Significant Relationship ◽

Chronic Kidney Failure ◽

P Value ◽

Risk Category ◽

Chi Square ◽

Routine Treatment

In 2006, the Indonesian Renal Registry (Pernefri) shows about 12,5% of people in Indonesia suffer from chronic kidney disease. The most common cause of chronic kidney disease in 2018 in Indonesia is 39% by renal hypertension and 22% by Diabetic Nephropathy. This cross-sectional study was conducted at "RT" Hospital in Jakarta from 2018 to 2019. The Independent variable in this research was comorbid hypertension and obedience treatment, whereas dependent variables were risk category for kidney deterioration progression and the causal relationship tested with Pearson Chi-Square and Fisher exact as an alternative test. The study included 26 respondents, with 17 (65.4%) patients having hypertension in diabetic nephropathy. Eighty percent of respondents who did not routinely seek treatment in the hypertension group had progression from kidney failure to the Deep Red (Highest Risk) category. Fisher Exact statistical test analysis in the group with a history of comorbidities in the form of hypertension found no significant relationship between non-routine treatment with the progression of chronic kidney failure in the Highest-Very Highest Risk category (p-value = 0.515). Still, a large risk was found in the non-group routine treatment with a chance of 1.33 (0.962 - 1.848) times to have the progression of chronic kidney failure in the category of Highest-Very Highest Risk. Can be concluded that controlling blood pressure and treatment proven to slow worsening kidney function in nephropathy diabetic, even though no significant relationship has been found due to lack of sample. Keywords: diabetic nephropathy; hypertension; prognosis AbstrakPerhimpunan Nefrologi Indonesia (Pernefri) tahun 2006 merilis data penderita gagal ginjal kronis di Indonesia sebesar 12,5%. Etiologi terbesar gagal ginjal kroniks menurut Indonesian Renal Registry tahun 2018 adalah penyakit ginjal hipertensi sebesar 39% dan nefropati diabetic sebesar 22%. Potong lintang pada pasien di RS”RT” Jakarta tahun 2018-2019. Variabel bebas dalam penelitian ini adalah komorbid hipertensi dan kepatuhan berobat, sedangkan variable tergantung dalam penelitian ini berupa kategori risiko progresifitas perburukan ginjal serta hubungan sebab akibat diuji dengan Peason Chi Square dan uji alternatif Fisher Exact Test. Penelitian berlangsung mengikutsertakan 26 responden, dengan prevalensi hipertensi pada pasien nefropati diabetik sebesar 17 (65,4%). Delapan puluh persen responden yang tidak rutin berobat pada kelompok hipertensi memiliki progresifitas penyakit gagal ginjal hingga kategori Deep Red (Highest Risk). Analisa uji statistik Fisher Exact pada kelompok dengan riwayat penyakit penyerta berupa hipertensi didapatkan tidak hubungan yang bermakna antara tidak rutin berobat dengan progresifitas penyakit gagal ginjal kronis kategori Highest-Very Highest Risk (p-value = 0,515) tetapi secara besar risiko didapatkan bahwa kelompok yang tidak rutin berobat memiliki risiko 1,33 (0,962 – 1,848) kali untuk memiliki progresifitas penyakit gagal ginjal kronis kategori Highest-Very Highest Risk. Dapat disimpulkan bahwa engontrol tekanan darah dan rutinitas berobat dapat memperlambat perburukan fungsi ginjal akibat komplikasi lanjut dari nefropati diabetikum, walaupun belum didapatkan hubungan yang bermakan dikarenakan kurangnya besar sampel pada penelitian ini.

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Induction of Chronic Kidney Failure in a Long-Term Peritoneal Exposure Model in the Rat: Effects on Functional and Structural Peritoneal Alterations

Peritoneal Dialysis International ◽

10.3747/pdi.2008.00272 ◽

2010 ◽

Vol 30 (5) ◽

pp. 558-569 ◽

Cited By ~ 12

Author(s):

François Vrtovsnik ◽

Annemieke M. Coester ◽

Deirisa Lopes–Barreto ◽

Dirk R. de Waart ◽

Allard C. Van der Wal ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Kidney Failure ◽

Wistar Rats ◽

Chronic Kidney Failure ◽

Disease Stage ◽

Exposure Model ◽

Peritoneal Membrane ◽

Peritoneal Function

BackgroundA long-term peritoneal exposure model has been developed in Wistar rats. Chronic daily exposure to 3.86% glucose based, lactate buffered, conventional dialysis solutions is possible for up to 20 weeks and induces morphological abnormalities similar to those in long-term peritoneal dialysis (PD) patients. The possible effects of kidney failure in this model are unknown. The aim was to analyze the effects of chronic kidney failure on peritoneal function and morphology, alone and in combination with PD exposure, in a well-established, long term, peritoneal exposure model in the rat.Methods40 male Wistar rats were randomly assigned into four experimental groups: no nephrectomy, no peritoneal exposure (sham; n = 8); nephrectomy, no peritoneal exposure (Nx; n = 12); no nephrectomy, with peritoneal exposure (PD; n = 8); and nephrectomy, with peritoneal exposure (NxPD; n = 12). The nephrectomy consisted of a one-step 70% nephrectomy. The peritoneal exposure groups were infused once daily for 16 weeks with a 3.86% glucose-based dialysis solution. Development of chronic kidney disease was monitored during the experiment. Peritoneal function and morphological assessment of the peritoneal membrane were performed at the end of the experiment.ResultsDuring follow-up the nephrectomized groups developed uremia with remarkable renal tubular dilatation and glomerular sclerosis in the renal morphology. Functionally, uremia (Nx) and PD exposure (PD) alone showed faster small solute transport and a decreased ultrafiltration capacity, which were most pronounced in the combination group (NxPD). The presence of uremia resulted in histological alterations but the most severe fibrous depositions and highest vessel counts were present in the PD exposure groups (PD and NxPD). Significant relationships were found between the number of vessels and functional parameters of the peritoneal vascular surface area.ConclusionIt is possible to induce chronic kidney failure in our existing long-term peritoneal infusion model in the rat. The degree of impairment of kidney function after 16 weeks is comparable to chronic kidney disease stage IV. Uremia per se induces both functional and morphological alterations of the peritoneal membrane. An additive effect of these alterations is present with the addition of chronic kidney failure to the model. The latter makes the present long-term model important in better understanding the pathophysiology of the peritoneal membrane in PD.

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Cuidados paliativos na doença renal crônica: uma revisão integrativa

Enfermagem em Foco ◽

10.21675/2357-707x.2013.v4.n2.516 ◽

2013 ◽

Vol 4 (2) ◽

pp. 75

Author(s):

Kely Regina Da Luz ◽

Pablo Henrique Schmitt ◽

Mara Ambrosina De Oliveira Vargas ◽

Jaime Alonso Caravaca Morera ◽

Julia Valeria De Oliveira Vargas Bitencourt ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Palliative Care ◽

Renal Failure ◽

Chronic Renal Failure ◽

Kidney Disease ◽

Renal Insufficiency ◽

Kidney Failure ◽

Chronic Renal Insufficiency ◽

Chronic Kidney Failure ◽

Palliative Care Team

Resumo: Revisão integrativa com artigos publicados de 2006 a 2012, constituindo-se como objetivo sintetizar a contribuição de pesquisas realizadas sobre os cuidados paliativos voltados para os pacientes com doença renal crônica, com os descritores “falência renal crônica, insuficiência renal crônica e cuidado paliativo”. Emergiram questões relacionadas à interação entre a equipe de cuidados paliativos e a equipe da nefrologia. Sinalizado que mesmo que os cuidados paliativos seja uma temática recente no currículo de Nefrologia, são cuidados que devem ser instituídos precocemente na evolução da doença renal crônica. Reforçado a valorização da autonomia e o desenvolvimento de competências em cuidados paliativos.Palavras-chave: Insuficiência Renal Crônica. Cuidado paliativo. Enfermagem.Palliative Care In Chronic Kidney Disease: An Integrative ReviewAbstrat: An integrative review with articles published from 2006 to 2012, aimed at synthesizing the contribution of research on palliative care focused on patients with chronic kidney disease, with the descriptors “ Chronic Kidney Failure, Chronic Renal Insufficiency, and palliative care.” Emerged issues related to the interaction between the palliative care team and the nephrology team. We highlighted that even though the palliative care is a recent topic in the Nephrology’s curriculum, the care should be instituted earlier in the course of chronic kidney disease. Reinforcing the value of the autonomy and the development of skills in palliative care.Keywords: Chronic Renal Failure. Palliative care. Nursing.Cuidados Paliativos En La Enfermedad Renal Crónica: Una Revisión IntegrativaResumen: Revisión integrativa con artículos publicados de 2006 a 2012, con el objetivo de sintetizar la contribución de investigaciones realizadas sobre los cuidados paliativos dirigidos para los pacientes con enfermedad renal crónica, con los descriptores “fallo renal crónico, insuficiencia renal crónico y cuidado paliativo”. Emergieron cuestiones relacionadas a la interacción entre el equipo de cuidados paliativos y el equipo de nefrología. Señalizando que aunque los cuidados paliativos sean una temática reciente en el currículum de Nefrología, son cuidados que deben ser instituidos precozmente en la evolución de la enfermedad renal crónica, reforzando la valorización de la autonomía y el desarrollo de competencias en cuidados paliativos.Palabras clave: Insuficiencia renal crónica, Cuidado paliativo, Enfermagem.

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Spectrum of Complications of Patients with Chronic Kidney Disease on Maintenance Continuous Ambulatory Peritoneal Dialysis: An Experience of Tertiary Nephrology Center in Najaf City-Iraq

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2021.7274 ◽

2021 ◽

Vol 9 (B) ◽

pp. 1529-1534

Author(s):

Evan Noori ◽

Rawaa Hadi ◽

Yasir Sharba ◽

Zahraa Fathi Sharba

Keyword(s):

Chronic Kidney Disease ◽

Peritoneal Dialysis ◽

Kidney Disease ◽

Kidney Failure ◽

Chronic Kidney Failure ◽

Infectious Complications ◽

Cross Sectional ◽

Dialysis Unit ◽

Open Operation ◽

Significant Difference

BACKGROUND: Chronic kidney disease (CKD), also called chronic kidney failure, is described as gradual loss of kidney function. CKD can progress to end-stage kidney failure, which is fatal without artificial filtering (dialysis) or kidney transplant. Peritoneal dialysis (PD) has a widespread renal replacement therapy with great acceptance because of simplicity, flexibility, and independence. AIM: The aim of this study was to evaluate the complications of continuous ambulatory PD (CAPD) in patients with CKD. METHODS: A cross-sectional study, involved 140 patients, aged between 18 and 80 years old and suffered from CKD under maintenance CAPD in the dialysis unit of the renal center. All data regarding the sociodemographic profile of the patient, vitals, etiological diagnosis, frequency and duration of dialysis, and dialysis-related complications were taken. RESULTS: In the current study, there is a significant difference in the distribution of complications among gender where the female patients had a higher incidence of both infectious and non-infectious complications. The study also reported that there is much lower rate of complications among patients on laparoscope operation in compared with the open operation. In addition, patients with open abdomen PD developed the complications earlier than those with laparoscope maintenance CAPD. CONCLUSION: Peritoneal infection is the most prevalent complication among the other complications in the current study. There is much lower rate of complications among patients on PD in compared with hemodialysis and on laparoscope in compared with the open operation.

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